جست‌وجوی استاد و پژوهشگر

• Parkinson's disease etiology and experimental therapeutics
• Developmental neurotoxicology of drugs of abuse
• Fetal dopamine neuron development
• +۵ مورد دیگر

Jack W. Lipton , PhD, serves as Chair and Professor of Translational Neuroscience at Michigan State University's College of Human Medicine. He directs the Lipton Lab at the Grand Rapids Research Center and holds a joint appointment with the MSU Neuroscience Program. Education: UC Berkeley (B.A. Psychology), UCLA (Ph.D. Behavioral Neuroscience) Prior institutions: Rush University Medical Center, University of Cincinnati Dr. Lipton's research spans two major domains: neurodegenerative disease and developmental neurotoxicology . His Parkinson's disease work focuses on: Alpha-synuclein pathology Gene therapy approaches Deep brain stimulation Neural transplantation Developmental studies examine: MDMA/cocaine effects on fetal dopamine neurons Neurite sprouting mechanisms Behavioral consequences of prenatal exposure Long-term CNS changes from drugs of abuse Key funding sources include: NIH (continuous since 1993) National Institute on Drug Abuse National Institute on Neurological Disorders Michael J. Fox Foundation Recent publications demonstrate expertise in: Alpha-synuclein fibril modeling Saliva-based diagnostics Neurotrophic factor genetics Aged animal model systems Scientific leadership includes: Director, Division of Neuropharmacology (UC 2004-2009) Founder, MSU Department of Translational Neuroscience Director, MSU Early Detection Program Chair, MSU Translational Science and Molecular Medicine Current initiatives focus on: Biomedical disaster preparedness University research analytics Saliva testing infrastructure Translational science leadership

Onur Basakمشاهده پروفایل

استادیار

• Neuroscience
• Developmental Biology
• Stem Cell Biology
• +۳ مورد دیگر

Onur Basak is an Assistant Professor at Utrecht University, affiliated with the University Medical Center Utrecht (UMCU), where he leads the "Single cell biology of neural cell identity" research group within the Brain Cancer strategic program. His research focuses on deciphering the mechanisms generating and maintaining human brain cellular diversity to understand brain function, cognitive dysfunction, and malignant growth. His primary research domains include Neuroscience , Developmental Biology , and Stem Cell Biology , with specialized focus on Brain Cancer Research and Organoid Technology . He employs cutting-edge methodologies like single-cell profiling and human brain organoid models to investigate neural cell identity specification, bridging fundamental developmental processes with pathological conditions such as neurodegenerative diseases and cancer. Analysis of his recent publications reveals a dominant trend in modeling neurological diseases through advanced organoid systems and dissecting neural development mechanisms. Key thematic threads include ALS/FTD pathology, synaptic dysfunction, brain regeneration pathways, and habenula development, all leveraging single-cell resolution techniques and innovative organoid-on-chip platforms for disease modeling and therapeutic target identification. Scientific Awards: None mentioned in available sources. Advising and Grants: While specific student names or grant details are absent from the provided text, his leadership of an active research group suggests supervision of graduate students and involvement in competitive funding mechanisms related to brain cancer and neural development research at Utrecht University. He directs the "Single cell biology of neural cell identity" research group, which operates at the intersection of regenerative medicine and neuro-oncology, utilizing human cerebral organoids and single-cell technologies to model brain development and disease processes within Utrecht University's strategic Brain Cancer program infrastructure.

Yijing Suمشاهده پروفایل

استادیار

• Gene Expression
• Neuroscience
• Adult Neurogenesis
• +۶ مورد دیگر

Yijing Su, Ph.D. is an Assistant Professor of Oral Medicine in the Department of Oral Medicine at the University of Pennsylvania School of Dental Medicine. Her research laboratory investigates the intricate mechanisms governing gene expression in a cell type-, brain regional-, tissue- and species-specific manner under physiological and pathological conditions. Dr. Su's research interests focus on fundamental neuroscience questions with particular emphasis on adult hippocampal neurogenesis, single-cell transcriptomics, and epigenetic regulation of neural development. Her work bridges molecular biology, neuroscience, and computational approaches to understand how gene expression patterns shape brain development, function, and disease across species. She employs cutting-edge techniques including deep single-soma RNA sequencing, organoid models, and transcription factor analysis to explore neural mechanisms from embryonic development through adulthood. Analysis of Dr. Su's publication record reveals a strong research trajectory focusing on neural development, particularly in the hippocampus and cortical regions. Her work spans comparative studies across species, human-specific neural features, and disease modeling using advanced organoid technologies. Her research has increasingly incorporated single-cell resolution approaches to understand cellular heterogeneity in neural tissues, with applications to understanding Alzheimer's disease and other neurological conditions. Dr. Su actively recruits postdoctoral candidates, graduate students from various departments, and research assistants (including undergraduate and post-BS students) for her laboratory. Her lab appears to be well-positioned to investigate fundamental questions about neural development and function using state-of-the-art genomic and cellular approaches.

Isabelle Cloez-Tayaraniمشاهده پروفایل

مدرس

• Neuroscience
• Autism Spectrum Disorders
• Nicotinic Acetylcholine Receptors
• +۳ مورد دیگر

Dr. Isabelle Cloez-Tayarani is a faculty member at the Institut Pasteur in Paris, France. She serves as a Lecturer in the Development and Plasticity of the Nervous System course, a five-week intensive program combining laboratory and lecture formats for advanced graduate and PhD students. Institutional affiliation: Institut Pasteur Academic role: Lecturer Her research focuses on neuroscience and neurodevelopmental disorders , particularly using human-induced pluripotent stem cells (iPSCs) to model autism spectrum disorders (ASD). Key areas include: Investigation of SHANK3 mutations and their impact on cortical neuron spinogenesis Analysis of Contactin gene variants (CNTN5/CNTN6) associated with auditory hypersensitivity in ASD Study of nicotinic acetylcholine receptors (α7 and α4β2 subtypes) in memory and addiction mechanisms Her recent publications emphasize neurodevelopmental modeling through human-mouse chimeric systems and in utero transplantation techniques. While she has not been explicitly mentioned as receiving awards in the provided texts, her work spans topics including: Neuronal connectivity and synaptic plasticity Neuroimmune interactions in inflammatory conditions Receptor dynamics in neurodegenerative contexts Dr. Cloez-Tayarani's research frequently involves collaborations with investigators like Thomas Bourgeron (genetics of ASD) and Uwe Maskos (nicotinic receptor signaling), and she has contributed to understanding how environmental factors and genetic mutations interact in neurodevelopmental pathology.

• Alzheimer's Disease
• Neurodegenerative Disorders
• Molecular Neuroscience
• +۶ مورد دیگر

Dr. Fiona Kerr is a Lecturer in the School of Applied Sciences at Edinburgh Napier University, specializing in neurodegenerative disease research with a focus on Alzheimer's disease mechanisms. Her work integrates molecular biology, Drosophila models, and clinical biomarker discovery to investigate pathways involving GSK-3, Nrf2, and tau phosphorylation. Affiliation: School of Applied Sciences, Edinburgh Napier University Contact: F.Kerr@napier.ac.uk | +44 131 455 3807 Her research centers on Alzheimer's disease pathogenesis, particularly examining: Role of GSK-3 in amyloid-beta toxicity and tau phosphorylation Nrf2-Keap1 pathway dysregulation in neurodegeneration Metabolic interventions (glucose transport, dietary restriction) Environmental factors like iron-oxide nanoparticles in Parkinson's pathology Development of peripheral biomarkers for early diagnosis Analysis of her publications reveals consistent use of Drosophila models to dissect molecular mechanisms, with recent work shifting toward therapeutic targeting of oxidative stress pathways. Her studies frequently demonstrate how inhibiting specific kinases or activating protective transcription factors can rescue neurotoxicity, suggesting novel treatment avenues. Scientific recognition includes: Alzheimer's Research UK funding for Nrf2 dysregulation studies RS Macdonald Charitable Trust grant investigating iron nanoparticles in Parkinson's Biochemical Society scholarship supporting summer research Dr. Kerr actively supervises research projects and collaborates with institutions including King's College London (Lovestone lab) and UCL. Her work bridges basic molecular research with translational applications, particularly in identifying druggable targets within the Nrf2 pathway. Current projects examine anthropogenic nanoparticles in neurodegenerative disease and novel effectors of Nrf2 dysregulation.

Jefferson Knightمشاهده پروفایل

استاد

• Protein-Membrane Interactions
• Single-Molecule Biophysics
• Insulin Secretion Mechanisms
• +۳ مورد دیگر

Jefferson Knight is a Professor in the Department of Chemistry at the University of Colorado Denver's College of Liberal Arts and Sciences. He serves as Faculty Director of the Office of Undergraduate Research and Creative Activities, demonstrating his commitment to student research development. His academic appointments span both teaching and research, with a focus on biochemistry and biophysical chemistry. Dr. Knight earned his B.S. in Chemistry from the University of North Carolina in 2000, followed by a Ph.D. in Pharmacology from Yale University in 2006. His postdoctoral training was completed in the laboratory of Prof. Joseph Falke at the University of Colorado Boulder, where he developed single-molecule fluorescence microscopy methods for studying protein-membrane interactions. His research program focuses on molecular interactions of proteins and lipid membranes, particularly those involved in insulin secretion. His laboratory investigates how membrane-targeting proteins dock to lipid membranes through specific recognition of lipid headgroups, electrostatic interactions, hydrophobic insertion, and protein-protein interactions. A major emphasis is understanding how defects in these processes may contribute to type II diabetes. His lab employs a diverse toolkit including fluorescence resonance energy transfer, single-molecule fluorescence microscopy, protein purification, and various spectroscopic techniques. Analysis of his recent publications reveals a consistent focus on synaptotagmins and synaptotagmin-like proteins (Slps), with particular attention to their C2 domains and membrane binding mechanisms. His work spans fundamental biophysical characterization to educational research, demonstrating both depth in his specialty and breadth in application. Recent trends show increasing collaboration with other researchers and expansion into diabetes-related mechanisms. Dr. Knight actively mentors undergraduate and graduate students in his laboratory, with numerous students listed as co-authors on publications. His educational contributions include developing innovative biochemistry curricula that integrate threshold concepts with information literacy skills. His lab provides research opportunities for students across multiple disciplines including Chemistry, Biochemistry, Biology, and Engineering. The Knight Laboratory maintains active collaborations within CU Denver and with external institutions, creating a vibrant research environment focused on understanding the molecular mechanisms of regulated exocytosis and membrane trafficking. His work bridges fundamental biophysics with physiological relevance to diabetes research.

• Neuroscience
• Neurodegenerative Diseases
• Neural Circuits
• +۴ مورد دیگر

Dr. Sabine Krabbe is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn. Her research focuses on neural circuits mediating adaptive learning and decision-making, particularly in relation to emotional/metabolic states and neurodegenerative diseases like Parkinson's. She employs advanced techniques such as single-cell activity measurements, optogenetics, and pharmacogenetics in mouse models. Her work explores how internal states (e.g., fear, hunger) modulate brain networks involving the ventral midbrain, striatum, and amygdala. She investigates pathological neuronal activity in early Parkinson's disease, linking it to cognitive and psychiatric symptoms preceding motor decline. Her lab also studies synaptic connectivity, neuronal diversity, and plasticity mechanisms using anatomical and molecular methods. Research trends include fear learning circuits , dopaminergic/GABAergic neuron interactions , neuroimaging in neurodegeneration , and cross-species behavioral comparisons . Key methodologies involve miniature microscopes , 3-photon imaging , and BRISC synaptic mapping . No scientific awards are mentioned in the provided text. Her lab actively participates in collaborative neuroscience initiatives and shares findings via open-access platforms. Current projects address how brain networks integrate internal states, pathological mechanisms in Parkinson's, and the role of neuromodulation in adaptive behavior.

• Behavioral Neuroscience
• Learning and Memory
• Neuroscience
• +۳ مورد دیگر

Dr. Jessica Leake is a researcher at the School of Psychology, The University of Sydney, and a member of the Charles Perkins Centre. She earned her Bachelor of Science with First Class Honours and the University Medal in Psychology from the University of New South Wales, followed by a PhD in behavioural neuroscience at the University of Sydney. Her research focuses on the interaction between positive and negative experiences in memory regulation, emphasizing the hippocampus and amygdala's roles in fear memory mechanisms. Education : BSc (First Class Honours, University Medal) in Psychology, UNSW; PhD in Behavioural Neuroscience, University of Sydney. Her work spans memory consolidation, neural ensemble activity, and the impact of context and time on fear acquisition. Recent publications highlight molecular substrates of conditioned fear and impairments in goal-directed action in Alzheimer’s models. She has secured grants from the Brain and Mind Centre and School of Psychology for projects like "Visualizing fear memories in the LH" and "The impact of social learning on fear memory development." Scientific Awards & Grants : 2025 Brain and Mind Centre/Engagement Collaborative Grants School of Psychology/Psychology ECR Pathways Funding

Mark D Bevanمشاهده پروفایل

استاد

• Neuroscience
• Basal Ganglia Research
• Parkinson's Disease
• +۳ مورد دیگر

Mark D Bevan is the Rose, James, Sarah & Max Meltzer Professor of Neuroscience at Northwestern University's Feinberg School of Medicine. He earned his PhD in 1993 from the University of Manchester, England. His laboratory focuses on the basal ganglia circuits critical for voluntary movement and associative learning, with particular emphasis on Parkinson's disease, Huntington's disease, obsessive-compulsive disorder, and addiction pathophysiology. Research interests center on: Defining principles of basal ganglia operation in health and disease Developing corrective or neuroprotective therapies for movement disorders Investigating subthalamic nucleus dysfunction in Parkinson's and Huntington's Neural circuit dynamics and plasticity in motor control systems Dopaminergic regulation of basal ganglia pathways His publication pattern shows consistent focus on basal ganglia circuitry, with recent work emphasizing: Movement optimization through subthalamic nucleus activity (2024) Early dysfunction in Huntington's disease models (2022) Parkinsonian network dynamics (2020) Therapeutic modulation of neural circuits (2018-2019) Honors and Awards: Javits Neuroscience Investigator Award, NIH-NINDS (2012) He leads the Mark Bevan Lab and is core faculty at the Northwestern University Institute of Neuroscience (NUIN). The lab currently has positions for postdoctoral researchers investigating Huntington's disease mechanisms.

Lefteris Zachariaمشاهده پروفایل

دانشیار

• Pharmacology
• Drug Development
• Estradiol Metabolite Biology
• +۹ مورد دیگر

Lefteris Zacharia is an Associate Professor at the University of Nicosia , School of Life and Health Sciences, Department of Health Sciences. He combines academic expertise with industry experience in pharmacology, drug development, and regulatory affairs. BSc in Biochemistry from Denison University (1998) PhD in Pharmacology from University of Pittsburgh School of Medicine (2002) MBA from Katz Graduate School of Business, University of Pittsburgh (2007) His research focuses on estradiol metabolite biology in Alzheimer’s disease, pre-eclampsia, and ischemia-reperfusion injury, alongside investigating inflammation resolution in cancer and cardiovascular diseases. He also explores peritoneal adhesions and nicotine metabolism inhibition for smoking cessation. Recent publications emphasize animal models for cognitive impairment, adrenergic receptor targeting in neurodegeneration, and in vitro systems for metastatic cancer research. His work bridges translational pharmacology and clinical applications . He has participated in European Union grants as principal investigator and NIH grants as co-investigator, with an h-index of 24 and over 1400 citations.

• Neurodevelopmental Disorders
• Neural Stem Cell Biology
• Brain Organoids
• +۴ مورد دیگر

Bennett G. Novitch is a Professor in the Department of Neurobiology at the David Geffen School of Medicine, UCLA. His research focuses on neurodevelopmental mechanisms in health and disease, particularly through brain organoid models of neuropsychiatric disorders and neurodevelopmental pathologies. Education : PhD in Biological Chemistry (Harvard), MMSc in Medical Sciences (Harvard Medical School), BS in Biological Sciences (University of Vermont), Postdoc in Biochemistry/Neurobiology (Columbia University) His research spans neural progenitor regulation , spinal cord development , motor neuron specification , organoid modeling , and Hedgehog/Notch signaling . Current projects include NIH-funded initiatives on neurodevelopmental disorders and HIV-associated neurocognitive impairment. Key publication trends show organoid modeling (15+ papers), neural progenitor regulation (12+ papers), spinal cord patterning (10+ papers), Hedgehog signaling (8+ papers), and transcriptional control (7+ papers). Notable collaborations include work with Samantha Butler, Ranmal Samarasinghe, and Kathrin Plath. He holds multiple NIH grants including: R01NS089817 (2015-2021): Cortical Growth Regulation R01NS085227 (2015-2021): Respiratory Motor Neuron Development R01DA051897 (2020-2025): HIV-Associated Neurocognitive Disorders R01MH130061 (2022-2026): Brain Organoid Neurodevelopment R01MH132651 (2023-2028): High-Throughput Neuropsychiatric Phenotyping His lab investigates neural development mechanisms using human stem cell models, with particular emphasis on motor neuron specification , radial glia dynamics , and transcriptional regulators like Foxp1 and Prdm16.

Stanley Watson Jrمشاهده پروفایل

استاد پژوهشی

• Neuroscience
• Gene Expression
• Psychiatric Disorders
• +۳ مورد دیگر

Stanley Watson Jr. is a Research Professor at the Michigan Neuroscience Institute within the University of Michigan . His research focuses on neuroscience , gene expression , and transcription factor dynamics in psychiatric disorders like schizophrenia and bipolar disorder. Recent publications highlight his work on: Cell-type specific gene expression reductions in interneurons Multiomic profiling of transcription factor binding in human brain tissue Long-term effects of early life stress on myelin-related gene expression Development of brain-specific functional gene set databases (Brain.GMT) Collaborations with Huda Akil and others have produced high-impact studies in journals like Nature Neuroscience and Genome Research . His work also explores stress resilience mechanisms and environmental enrichment effects using rodent models.

• Ophthalmology
• Retinal Surgery
• Vitreoretinal Disease
• +۵ مورد دیگر

Rajeev S. Ramchandran, M.D., M.B.A. is an Associate Professor in the Department of Ophthalmology at the University of Rochester School of Medicine and Dentistry, specializing in Retina & Vitreous Services at the Flaum Eye Institute. He is a board-certified ophthalmologist with extensive clinical experience in retinal surgeries, laser therapy, intravitreal injections, and medical retina care. His research interests span multiple domains including telemedicine applications in ophthalmology, diabetic retinopathy screening protocols, retinal imaging technology, health policy and economics, and international ophthalmology. Dr. Ramchandran has developed significant expertise in implementing teleophthalmology programs to improve diabetic retinopathy surveillance in primary care settings and urban low-income populations. Analysis of his recent publications reveals a strong focus on retinal imaging technology development, teleophthalmology program evaluation, and the intersection of eye care with broader health systems. His work demonstrates consistent contributions to improving access to eye care in rural communities and underserved populations through innovative telemedicine solutions. John M. Brophy Award (2013) Operations Faculty Award (2013) Beta Sigma Gamma Honor Society member (2013) Distinction in Research during medical school (2003) Summa Cum Laude graduate from University of Pennsylvania (1998) Phi Beta Kappa member (1998) Dr. Ramchandran actively contributes to clinical education and has participated in numerous research collaborations across disciplines including oncology, pulmonology, and neuroscience. His laboratory work has included significant contributions to understanding vascular biology, ciliogenesis mechanisms, and molecular pathways in retinal disease. He maintains an active clinical practice serving patients in the Rochester area, Finger Lakes Region, and Western New York.

• Biomedicine
• Neurosciences
• Cell Biology
• +۵ مورد دیگر

Enrico Tongiorgi is a Full Professor at the Department of Life Sciences , University of Trieste , with a focus on Biomedicine and Neurosciences . He leads the Cellular and Developmental Neurobiology research group and serves as a member of doctoral study boards including Molecular Biomedicine and Neurosciences and Cognitive Sciences . His work spans pharmacological interventions for Rett Syndrome , molecular mechanisms of BDNF (Brain-Derived Neurotrophic Factor) in neurodevelopment, and drug screening for neurodegenerative disorders. Research Interests : Neurosciences, Cell Biology, Developmental Biology, Pharmacology, Biomedical Engineering, and Neurodegenerative Disease Therapeutics. Key Publications : Focus on BDNF signaling, mirtazapine's neuroprotective effects, and computational approaches to Rett Syndrome drug discovery. Scientific Collaborations include involvement in the Drug Screening Center ProRett and projects like Repurposing Mirtazapine in Rett Syndrome . His research integrates in vitro models, pharmacogenomics, and neurotrophic factor studies to address translational challenges in neurodevelopmental and neurodegenerative disorders.

• Comparative Anatomy
• Cell Biology
• Developmental Biology
• +۳ مورد دیگر

Prof. Gabriele Baj is an Associate Professor at the Department of Life Sciences, University of Trieste. He is a member of multiple Boards of Studies for academic programs including Neuroscience, Functional Genomics, and Biological Sciences. His research bridges Comparative Anatomy, Cell Biology, and Developmental Biology with a focus on Neuroscience and Mitochondrial Biology. His work investigates oxinflammatory mechanisms in neurodevelopmental disorders like Rett Syndrome, emphasizing mitochondrial dysfunction and inflammasome activation. Additional research areas include biotechnology applications in photodynamic therapy, cardiac tissue modeling, and synaptic plasticity regulation via receptor trafficking. Recent publications highlight trends in Neuroscience, Cell Biology, and Biotechnology. Key themes are mitochondrial abnormalities in Rett Syndrome, intestinal organoid modeling for gliadin interactions, and mechanobiology studies on cell-substrate dynamics. Prof. Baj actively participates in multidisciplinary research projects such as Dissecting the oxinflammatory mechanisms involved in Rett Syndrome (active) and ALL-MICRO (active), funded by entities like Beneficentia Stiftung and the European Commission.