معرفی
Mark D Bevan is the Rose, James, Sarah & Max Meltzer Professor of Neuroscience at Northwestern University's Feinberg School of Medicine. He earned his PhD in 1993 from the University of Manchester, England. His laboratory focuses on the basal ganglia circuits critical for voluntary movement and associative learning, with particular emphasis on Parkinson's disease, Huntington's disease, obsessive-compulsive disorder, and addiction pathophysiology.
Research interests center on:
- Defining principles of basal ganglia operation in health and disease
- Developing corrective or neuroprotective therapies for movement disorders
- Investigating subthalamic nucleus dysfunction in Parkinson's and Huntington's
- Neural circuit dynamics and plasticity in motor control systems
- Dopaminergic regulation of basal ganglia pathways
His publication pattern shows consistent focus on basal ganglia circuitry, with recent work emphasizing:
- Movement optimization through subthalamic nucleus activity (2024)
- Early dysfunction in Huntington's disease models (2022)
- Parkinsonian network dynamics (2020)
- Therapeutic modulation of neural circuits (2018-2019)
Honors and Awards:
- Javits Neuroscience Investigator Award, NIH-NINDS (2012)
He leads the Mark Bevan Lab and is core faculty at the Northwestern University Institute of Neuroscience (NUIN). The lab currently has positions for postdoctoral researchers investigating Huntington's disease mechanisms.
