جست‌وجوی استاد و پژوهشگر

Trond Vidar Hansenمشاهده پروفایل

استاد

• Organic Chemistry
• Biochemistry
• Pharmacology
• +۳ مورد دیگر

Trond Vidar Hansen is a Professor at the Department of Pharmacy, University of Oslo , and leads the LIPCHEM research group . He collaborates with institutions including the University of Bergen and Vestlandets Innovasjonsselskap through the VITADEL project, which recently received NOK 5,000,000 in verification support from the Research Council of Norway. His research focuses on the synthesis and biological evaluation of specialized pro-resolving lipid mediators derived from omega-3 fatty acids, with applications in inflammation resolution, neuroinflammation, and drug development. University : University of Oslo Department : Department of Pharmacy Research Group : LIPCHEM Collaborations : University of Bergen, Vestlandets Innovasjonsselskap Research Interests : H Hansen's work centers on the organic synthesis of bioactive lipid derivatives, particularly pro-resolving mediators from omega-3 polyunsaturated fatty acids. His team investigates their roles in inflammatory disease models , neuroinflammation , and PPAR receptor activation , aiming to develop therapeutic agents for conditions like chronic pain, diabetes, and neurodegenerative disorders. The research integrates stereoselective chemistry , biochemical profiling , and pharmacological evaluation to validate these mediators' clinical potential. Recent Awards : 2025: NOK 2,000,000 verification support from Research Council of Norway 2025: Co-leader of NOK 5,000,000 VITADEL project Publications : His articles (2015–2024) reveal a focus on stereoselective synthesis of resolvins, protectins, and maresins, with applications in anti-inflammatory and neuroprotective therapies . Key subfields include omega-3 metabolite profiling , PPAR agonist design , and biosynthetic pathway elucidation , often utilizing human cell models and mouse disease models . Collaborative projects emphasize commercialization of academic research and translational medicine .

Anne Berit C. Samuelsenمشاهده پروفایل

دانشیار

• Polysaccharide Chemistry
• Pharmacognosy
• Carbohydrate Polymers
• +۴ مورد دیگر

Anne Berit C. Samuelsen serves as Associate Professor at the Department of Pharmacy, University of Oslo, where she also holds the position of Head of Education. Her academic foundation includes a Cand.pharm. degree and Dr.scient. doctorate, establishing her expertise in pharmaceutical sciences. Her research centers on polysaccharides from natural sources—particularly higher plants, cereals, and fungi (Basidiomycota)—with specialized focus on β-glucans. Key interests include carbohydrate chemistry, pharmacognosy, and the development of biopolymer-based pharmaceutical applications. Her work bridges fundamental structural characterization with practical drug delivery solutions, notably through liposome coating technologies and immunomodulatory compound development. Recent publications reveal a strong trajectory in fungal polysaccharide research, particularly with Pleurotus eryngii and Albatrellus ovinus species. Her team employs advanced techniques like diffusion-ordered NMR spectroscopy to analyze polysaccharide structures while investigating biological activities related to immune receptor binding (Dectin-1, Toll-like receptors) and therapeutic applications. This work demonstrates consistent output in high-impact journals including Carbohydrate Polymers and ACS Applied Bio Materials . She actively contributes to academic instruction through courses such as FARM1150 (Pharmaceutically Oriented Biochemistry), FARM3100 (Pharmacognosy), and FARM5200 (Use of Biopolymers in Pharmaceuticals). Her leadership extends to the Bioactive Natural Substances and Health Effects (BioNatH) research group and the Glyconor Consortium, where she investigates natural product applications for health improvement.

• TGF-β family signaling
• Multiple myeloma
• Cancer research
• +۷ مورد دیگر

Toril Holien is Professor at the Department of Biomedical Laboratory Science, Faculty of Natural Sciences, Norwegian University of Science and Technology (NTNU). Her research centers on TGF-β family signaling in multiple myeloma and other cancers, dissecting how ligands such as TGF-β, activins, BMPs and GDFs modulate SMAD-dependent transcription and apoptosis. She leads a vibrant group that welcomes graduate and visiting students, and she has co-authored >50 peer-reviewed papers since 2008. Research Interests Transforming growth factor-β (TGF-β) superfamily signaling in cancer Multiple myeloma biology and therapy resistance SMAD1/5-mediated apoptosis and c-MYC repression Tumor microenvironment, angiogenesis and dissemination Bone morphogenetic proteins (BMPs) and bone disease in myeloma Translational use of photodynamic therapy and extracorporeal photopheresis Her recent publications reveal a translational trajectory spanning in-vitro mechanistic studies, pre-clinical mouse models and early-phase clinical trials. A dominant theme is the exploitation of BMP/SMAD signaling to overcome myeloma cell survival, alongside biomarker-driven prediction of drug sensitivity. Scientific Recognition Principal Investigator on multiple national and international projects Extensive collaboration network evidenced by multi-institutional publications Invited reviews in Cytokine & Growth Factor Reviews and other high-impact journals Advising & Grants Current PhD students: Md Abu Hanif (Edan), Eli Svorkdal Hess Current master’s students: Iben Qiu Yang Brøgger, Fenne Pien Breukink Former graduates: Ingrid Quist-Løkken (PhD/MD 2025), Clara Andersson-Rusch (PhD 2024), Oddrun Elise Olsen (PhD 2017 & 2020) Hosts Erasmus and visiting trainees annually Her laboratory is embedded within NTNU’s translational cancer research environment, offering cutting-edge facilities for cell biology, molecular profiling and animal models.

• Marine Biotechnology
• Natural Products Chemistry
• Metabolomics
• +۳ مورد دیگر

Espen Holst Hansen is a Professor of Marine Biotechnology and Deputy Head of Research at the UiT The Arctic University of Norway 's Norwegian Fisheries College . His work focuses on marine natural product discovery and chemical characterization of bioactive compounds from Arctic plants, animals, and microorganisms, with applications in drug development and nutraceuticals. Using advanced techniques like mass spectrometry and chromatography , Hansen leads projects such as the SuReMetS initiative (Sustainable Resources for Metabolic Syndrome management) and contributes to the MAR-BIO platform for Arctic bioprospecting. His research spans metabolomics , antimicrobial compound isolation , and marin bioprospecting for pharmaceutical and industrial applications. Recent publications highlight his work on kinase inhibitors from Arctic hydrozoans, novel antibacterial compounds from marine fungi, and bioactive lipids from diatoms. Collaborations include institutions like Frontiers Media and Nature Publishing Group . Hansen also teaches BIO-2606 General and Marine Biotechnology at UiT.

• Antimicrobial peptides
• Antibiofilm agents
• Marine bioprospecting
• +۷ مورد دیگر

Ataur Rahman is a Postdoctoral Research Fellow in Analytical Chemistry and Microbiology at the Department of Chemistry, UiT The Arctic University of Norway. He is actively working on the NFR-funded CandRAS (Competence and education in land-based production of salmon in recirculation aquaculture systems) project linked to NFH, Nofima and Tromsø Aquaculture Research Station (Havbruksstasjonen i Tromsø). Dr. Rahman's research focuses on discovering and developing novel antimicrobial compounds from marine resources, particularly those with potential to combat antibiotic resistance and biofilm formation. His work spans water chemistry (TOC, DOC, DOM), metabolomics, proteomics, salmon, RAS (Recirculating Aquaculture Systems), and aquaculture applications. His extensive publication record demonstrates expertise in chemical synthesis of antimicrobial peptides, heterocyclic compounds with membranolytic properties, and marine-derived antibiofilm agents. Dr. Rahman's research shows a clear progression from fundamental marine bioprospecting to applied therapeutic development, with particular emphasis on structure-activity relationships and toxicity profiling of novel antimicrobial compounds. Dr. Rahman is a member of the Marine Bioprospecting research group and the Chemical Synthesis and Analysis team at Realfagbygget C418. His collaborative work spans multiple institutions including NFH, Nofima, and Tromsø Aquaculture Research Station, reflecting the interdisciplinary nature of his research at the intersection of chemistry, microbiology, and aquaculture.

Pål Rongvedمشاهده پروفایل

استاد

• Medicinal Chemistry
• Drug Discovery and Design
• Antibiotic Resistance
• +۱۰ مورد دیگر

Pål Rongved is a Professor in Medicinal Chemistry at the Department of Pharmacy, University of Oslo , with a career spanning academia and industry. His research focuses on medicinal chemistry , antibiotic resistance , AML therapy , and metal-chelating drug design . Key affiliations: Director at Patias Innovation Ltd , Innovation Advisor roles (2003-2011), and EU COST network ZINC-NET (2012–present). Education: Dr. Philos. (2000), Cand.scient. in Organic Chemistry (1981), Master of Arts (1978), all from University of Oslo. His research interests integrate drug discovery , organic synthesis , and bioactive compound development across: Antibiotics (linked to the ZinChel project) Antiviral agents targeting SARS-CoV AML therapies (acute myeloid leukemia) LXR receptor modulators for metabolic diseases Aquaporin regulation via zinc complexing agents Scientific contributions include zinc-chelating compounds to reverse carbapenem resistance , cyclodextrin-based solubility enhancement for drugs, and oxysterol mimics for nuclear receptor modulation. Collaborations span Adjutec Pharma AS , CIME , and SYNPHASE .

• Organic Chemistry
• Biocatalysis
• Asymmetric Synthesis
• +۳ مورد دیگر

Elisabeth Egholm Jacobsen is an Associate Professor in the Department of Chemistry at NTNU, specializing in organic chemistry and biocatalysis. Her research focuses on synthesizing biologically active molecules using enzyme-catalyzed methods, particularly enantiomerically pure drugs via kinetic resolution or asymmetric synthesis. She has led EU projects like GreenCAM (2019–2022) and contributes to the European Society of Applied Biocatalysis (ESAB), serving as Treasurer since 2023. Jacobsen teaches organic chemistry courses for technology students and advanced organic synthesis laboratory modules. Her work emphasizes green chemistry and collaborative projects with institutions like the University of Bucharest. She has mentored numerous master’s students and co-authored over 50 peer-reviewed publications, covering topics from biocatalytic synthesis to educational methodologies. Education: Cand. scient. (1994), M.Sc. in Biotechnology (1999), Ph.D. in Organic Chemistry (2004, NTNU). Career: Senior Engineer (2004), Associate Professor (2005–present). Collaborations include the Systems Biocatalysis project (concluded 2017) and multiple EU-funded initiatives. She is a Scientific Committee Member of ESAB and actively engages in catalysis research, environmental applications, and educational technology. Key research themes include chemo-enzymatic protocols for β-blockers, Ru-based catalysts for lactic acid conversion, and biocomposite materials. Her teaching innovations include digital resources like WileyPLUS and instructional videos for laboratory courses. Jacobsen’s contributions bridge organic chemistry, biocatalysis, and sustainable chemical engineering, reflecting her commitment to advancing both scientific and pedagogical practices.

• Natural Products Chemistry
• Medicinal Chemistry
• Antimicrobial Resistance
• +۳ مورد دیگر

Professor Johan Mattias Isaksson leads the UiT NMR Laboratory and manages the Norwegian NMR Platform (NNP) node and the SmallStruct analytical platform at the Department of Pharmacy, UiT The Arctic University of Norway . He teaches Medicinal Chemistry (FAR-2301) , Advanced Pharmaceutical Chemistry (FAR-3301) , and NMR Spectroscopy (KJE-3303/8303) , integrating cutting-edge methods into his courses. His research focuses on natural products chemistry and medicinal chemistry , leveraging marine organisms (e.g., Arctic fungi, bacteria, sponges) to discover antibacterial and anticancer agents . His work combines NMR spectroscopy , metabolomics , and computational modeling to characterize compound structures and interactions with biomembranes . Recent studies highlight his team's discovery of novel antibacterial sesterterpenes (2025), dUTPase inhibitors for cancer (2024), and σ-factor engineering approaches in Actinoplanes sp. (2024). He also develops membrane model systems to study multi-resistant bacteria via techniques like microscale thermophoresis and Vibrational Circular Dichroism . Professor Isaksson collaborates with international researchers and contributes to projects like Lead-to-drug development of amphipathic scaffolds (LEADScAMR) and bacterial membrane mimetics . His publications span journals such as Journal of Natural Products , Marine Drugs , and Journal of Medicinal Chemistry , emphasizing marine biotechnology and antimicrobial resistance solutions.

Tom Luk R Michoelمشاهده پروفایل

استاد

• Bioinformatics
• Computational Biology
• Machine Learning
• +۳ مورد دیگر

Tom Luk R Michoel is a Professor at the Computational Biology Unit within the Department of Informatics at the University of Bergen. His research focuses on bioinformatics, computational biology, and machine learning applied to understanding gene regulation and causal relationships in biological systems. He teaches in both the Bachelor and Master programs in Informatics, including courses like BINF301 and MNF130. Research Interests: Michoel’s work explores how genetic variation influences gene expression and disease mechanisms. He develops machine learning algorithms to infer causal gene regulatory networks from large-scale genomic data, emphasizing causal inference over mere correlations. His recent projects include analyzing plasma protein networks linked to cardiovascular disease and applying Bayesian networks to understand gene-disease associations. Publications: His most recent work (2025) focuses on causal protein networks in myocardial infarction risk and network-driven frameworks for coronary artery disease studies. He also contributes to methodological advancements like integrating graph neural networks with metabolic models. Current Activities: Michoel leads the development of tools like Findr.jl for network inference and teaches short courses on causal inference in drug discovery. His lab collaborates on projects involving single-cell analysis, multi-tissue genomics, and systems pharmacology.

Jeannette Nilsenمشاهده پروفایل

پژوهشگر ارشد

• Biochemistry
• Pharmacology
• Biomedical Engineering
• +۳ مورد دیگر

Jeannette Nilsen is a Postdoctoral Fellow at the Department of Pharmacology, University of Oslo (UiO). Her research focuses on protein engineering, pharmacology, and biomedical applications, particularly involving albumin and the neonatal Fc receptor (FcRn) interactions. Current Position: Postdoctoral Fellow Institution: University of Oslo Department: Pharmacology Email: jeannette.nilsen@medisin.uio.no Her work explores mechanisms of plasma half-life extension, mucosal drug delivery, and albumin-based therapeutics. Recent publications highlight collaborations with international researchers on FcRn-targeted nanosystems, engineered albumin fusions, and their applications in diabetes, hemophilia, and cancer treatments. Key trends in her research include pH-dependent albumin binding , transmucosal delivery , and optimizing biologics via FcRn affinity . All 15 articles emphasize interdisciplinary approaches bridging biochemistry, immunology, and pharmacology.

Ruth Brenkمشاهده پروفایل

استاد

• Structure-Based Drug Design
• Computational Chemistry
• Drug Discovery
• +۹ مورد دیگر

Ruth Brenk is a Professor at the Department of Biomedicine, Faculty of Medicine, University of Bergen (UiB), and an associated member of the Computational Biology Unit. She leads the Brenk Lab, which focuses on advancing structure-based drug design through the integration of computational and experimental approaches. Research Interests: Her work centers on improving methods for structure-based drug design, particularly targeting enzymes with biological significance. Key areas include RNA-ligand interactions (especially riboswitches as antibiotic targets), protein-ligand interactions in conserved binding sites, and druggability prediction for both protein and RNA targets. Her lab emphasizes the synergy between theoretical modeling and experimental validation. Recent Publications Trend: Analysis of her latest publications (2021–2025) reveals a strong focus on antibiotic discovery, particularly against Pseudomonas aeruginosa via FabF/FabB inhibition using fragment screening and X-ray crystallography. There is a growing emphasis on RNA as a drug target, including tools like DrugPred_RNA and participation in the TargetRNA EU network. Her work also explores metalloenzyme inhibitors and the quality of screening libraries (e.g., EU-OPENSCREEN). Scientific Awards: While no personal awards are listed, her research group has achieved recognition, including a prize for the second-best oral presentation at the 34th Molecular Modeling Workshop 2020 awarded to group member Illimar Rekand. Advising and Grants: Ruth Brenk actively mentors multiple PhD candidates and postdoctoral researchers. She leads significant funded projects, including the EU Horizon-funded TargetRNA MSCA network, a Centre for Digital Life Norway project on responsible innovation in drug discovery for antibiotics and COPD, and work on Ribotacs funded through EU-OPENSCREEN. These projects highlight her leadership in interdisciplinary, collaborative research. Labs and Teams: The Brenk Lab is part of the 'Structural Biology and Drug Discovery' research unit at UiB. The lab collaborates closely with researchers from the Department of Chemistry, including Nathalie Reuter and Bengt-Erik Haug, and participates in international consortia such as EU-OPENSCREEN and Digital Life Norway.

Terje Johansenمشاهده پروفایل

استاد

• Autophagy
• Selective autophagy
• Cell biology
• +۵ مورد دیگر

Terje Johansen is a Professor of Biochemistry and Cell Biology at UiT The Arctic University of Norway. He serves as research group leader for the Autophagy Research Group and scientific leader of the Proteomics and Metabolomics core facility (PRiME) at UiT. His primary research focus is on mechanistic basic research within selective autophagy. Professor Johansen's research interests span across multiple areas of cellular biology with emphasis on: Autophagy and selective autophagy mechanisms Cell signaling pathways Biochemical regulation of cellular processes Cancer research related to autophagy pathways Neurodegenerative disease mechanisms Gene regulation in cellular stress responses His recent publications (2021-2025) demonstrate a strong focus on selective autophagy mechanisms, particularly examining ATG8 protein interactions, LIR motif functions, and the role of autophagy in cellular stress responses, cancer, and neurodegenerative conditions. His work often involves interdisciplinary approaches combining molecular biology, biochemistry, and computational methods. Professor Johansen has received recognition for his contributions to autophagy research through numerous high-impact publications in prestigious journals such as Nature Communications, Molecular Cell, Autophagy, and Journal of Cell Biology. He is actively involved in teaching at UiT, offering courses including: MBI-2001 Biokjemi (Biochemistry) MBI-2012 Molecular Cell Biology - Cell Structure MBI-3004 The Biology of Cancer MBI-3012 Advanced Methods in Experimental Biomedicine MBI-8007 Molecular and Clinical Aspects of Cancer - Block I Professor Johansen leads the Autophagy Research Group and is involved in multiple research projects including "Mitophagy Mechanisms in Cancer Drug Resistance" and previously led "Autophagy-regulated Signalosomes in Cellular Stress and Disease Pathways" (2016-2021).

Ivan Violaمشاهده پروفایل

استاد

• Medical Visualization
• Molecular Visualization
• Data Visualization
• +۳ مورد دیگر

Ivan Viola is a Professor at the University of Bergen's Department of Informatics. His research focuses on medical and molecular visualization, with a particular emphasis on biomedical applications such as fetal ultrasound analysis, protein interactions, and biomolecular dynamics. He leads the VisGroup, developing tools like COZOID for protein-protein interaction analysis and The Vitruvian Baby for fetal ultrasound standardization. His work spans interdisciplinary collaborations, integrating computer science with biology and medicine. Key contributions include advancements in visualization techniques for physiological data, molecular dynamics simulations, and real-time data processing. He has published extensively in top journals and conferences, addressing challenges in data exploration, abstraction, and interactive visualization. Viola's research impacts fields such as prenatal diagnostics, drug discovery, and medical imaging, with tools like Watergate for water trajectory analysis and cellVIEW for multi-scale biomolecular rendering. His projects emphasize user-driven design and the development of intuitive visualization solutions for complex scientific data.

• Antimicrobial peptides
• Marine bioprospecting
• Drug resistance mechanisms
• +۲ مورد دیگر

Hymonti Dey is an Associate Professor at the Norwegian Fisheries College, part of UiT The Arctic University of Norway . Her research focuses on marine-derived antimicrobial peptides , novel heterocyclic antibiotic scaffolds , and mechanisms of bacterial resistance and biofilm formation . She has published extensively in biochemical and pharmaceutical journals, with recent work appearing in Journal of Peptide Science and Frontiers in Microbiology . Her research spans: Design and optimization of marine peptide analogues Hydantoin and barbiturate-based antimicrobial development Combination therapies for enhanced antibiotic efficacy Investigating bacterial resistance mechanisms Current trends in her publications emphasize membranolytic properties , structure-activity relationships , and applications against drug-resistant pathogens . Dey collaborates extensively with researchers like Tor Haug and Hans-Matti Blencke on projects related to marine bioprospecting. She is affiliated with the Marine Bioprospecting research group and contributes to advancing antimicrobial solutions through natural product-inspired design.

Julie Elisabeth Heggelundمشاهده پروفایل

پژوهشگر

• Immunology
• Structural Biology
• Antibiotic Resistance
• +۳ مورد دیگر

Dr. Julie Elisabeth Heggelund is a researcher at the Department of Immunology and Transfusion Medicine (Oslo University Hospital/University of Oslo). She works on interdisciplinary projects including celiac disease immunology and antibiotic resistance mechanisms , using structural biology techniques like X-ray crystallography and phage display. Her research focuses on: Gluten-antibody interactions in celiac disease Membrane proteins in multidrug-resistant tuberculosis (FRIPRO project) Structural analysis of bacterial toxins (cholera, ETEC) Recent publications (2025-2012) span autoimmune diseases , infectious disease mechanisms , and structural enzymology . She received the Brainpower Award 2021 (consolation prize) for science communication. Academic background: PhD in Structural Biology (UiO, 2015) MSc in Molecular Biosciences (UiO, 2011) BSc in Molecular Biology (UiO, 2009) Teaching roles include: Lecturer for Biochemistry 1 (KJM1140, 2019/2022) and group teaching in structural biology, biochemistry, and macromolecular analysis.