جستجوی استاد راهنمای دانشگاهی

Didier Trono is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL), where he leads the Laboratory of Virology and Genetics (LVG) within the School of Life Sciences. Formerly, from 2004 to 2012, he served as the founding dean of EPFL's Faculty of Life Sciences, orchestrating its development and growth during this formative period. Trono received his medical education at the University of Geneva, followed by clinical training in pathology, internal medicine, and infectious diseases in Geneva and at Massachusetts General Hospital in Boston. His scientific career began at the Whitehead Institute of MIT, and in 1990 he was recruited by the Salk Institute of San Diego to launch an AIDS research center. After seven years in the United States, he returned to Europe and eventually joined EPFL. Dr. Trono's research has evolved significantly over his career. Initially focusing on virus-host interactions, he studied pathogens like HIV and Hepatitis B virus, creating HIV-derived genetic transfer tools that are now successfully used in gene therapy. For approximately the last fifteen years, his research has centered on epigenetics, particularly exploring the impact of retroelements and their control mechanisms on development and physiology of higher organisms, including humans. His laboratory investigates how transposable elements and KRAB zinc finger proteins regulate gene expression, with important implications for understanding cancer biology and developing new diagnostic and therapeutic approaches. Analysis of his recent publications (2022-2024) reveals a strong focus on transposable elements, KRAB zinc finger proteins, and their roles in gene regulation and cancer. His work combines molecular biology, genomics, and bioinformatics approaches to understand how these ancient viral remnants have been co-opted by the host genome to regulate development and cellular functions. The research spans basic molecular mechanisms to potential clinical applications in cancer diagnosis and therapy, with some recent work also addressing SARS-CoV-2 and immune responses. Throughout his career, Professor Trono has mentored numerous PhD students, including Bojkowska Karolina, Brandão Sanches Vong Martins Filipe Amândio, Bulliard Yannick, Coluccio Andrea, Corsinotti Andrea, Coudray Alexandre, De Tribolet-Hardy Jonas Caspar, and Dorschel Iris Arianna. His laboratory has received significant funding to support research at the intersection of virology, genetics, and epigenetics, contributing to EPFL's reputation as a leading institution in life sciences research. The Trono Laboratory continues to be at the forefront of research on retroelements and their regulatory mechanisms, maintaining a vibrant research environment that bridges fundamental biological questions with potential medical applications, particularly in cancer research and precision medicine.

• Epigenetics
• Retroelements
• Transposable elements
• +۵ مورد دیگر

Pascal Frossard is a Full Professor at the Department of Electrical Engineering in the School of Engineering (STI) at EPFL, with a courtesy appointment in the School of Computer and Communication Sciences. He founded and directs the LTS4 laboratory since 2003, co-leads the EPFL AI Center and Swiss Data Science Center, and serves as Associate Dean for Research at STI. Research Focus: Machine Learning, Graph Signal Processing, AI Applications in Healthcare, Computer Vision Academic Leadership: IEEE Fellow, ELLIS Fellow, Conference Chair roles Key Projects: Digital Pathology for Oncology, Cardiac Digital Twins, Robust Machine Learning Research Interests: His work bridges signal processing, machine learning, and applied mathematics, emphasizing biomedical applications. Recent research includes adversarial robustness in classifiers, network representation learning, and 360-degree video analysis. Scientific Awards: IEEE Fellow ELLIS Fellow Leadership in IEEE technical committees Advising & Grants: Supervised 20+ PhD students and postdocs. Secured major grants from PHRT, Hasler Foundation, FNS-Sinergia, Armasuisse, Google, and Cisco.

• Machine Learning
• Data Science
• Graph Signal Processing
• +۶ مورد دیگر

Pierre Vandergheynst is a Full Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) in the Department of Electrical Engineering, with a courtesy appointment in Computer and Communication Sciences. He serves as EPFL’s Vice-Provost for Education since 2015 and leads the Signal Processing Laboratory 2 (LTS2). His research spans harmonic analysis, sparse approximations, mathematical data processing, and applications in signal/image processing, computer vision, machine learning, and graph-based data analysis. PhD in Mathematical Physics (1998), Université catholique de Louvain Postdoctoral Researcher at EPFL (1998-2001) Assistant Professor at EPFL (2002-2007) His research explores geometry/symmetry in high-dimensional data, redundant dictionaries for dimensionality reduction, and computational harmonic analysis on manifolds. Recent work focuses on protein structure modeling, geometric deep learning, and graph-based signal processing. Key article trends include graph neural networks for protein analysis, geometric deep learning in neuroscience, and structured knowledge priors in neural models. His 2023-2025 publications emphasize interpretable AI, long-range dependencies in graphs, and molecular representation learning. Scientific Awards: IEEE Signal Processing Magazine Best Paper Award (2023) Signal Processing Society Best Paper Award (2022) Apple ARTS Award (2007) De Boelpaepe Prize, Royal Academy of Sciences of Belgium (2009-2010) He has supervised over 30 PhD theses and contributed to foundational work in graph signal processing, compressive sensing, and geometric deep learning. His lab develops tools for data science on non-Euclidean structures, with applications in medicine, astronomy, and wireless systems.

• Data Science
• Machine Learning
• Computational Harmonic Analysis
• +۶ مورد دیگر

Prof. Knut Drescher is an Associate Professor at the Biozentrum, University of Basel , leading a research group focused on bacterial biofilms , swarming , and microbial multicellularity . Previously, he served as a Professor of Biophysics and Max Planck Research Group Leader at Philipps-Universität Marburg (2015-2021) and conducted postdoctoral research at Princeton University. Research Interests: Physical and biological mechanisms of biofilm formation Cell-cell interactions in microbial communities Antibiotic resistance in biofilms Hydrodynamics of bacterial swarms Evolution of cooperation in multispecies biofilms Development of bioimaging software (BiofilmQ, BacStalk) Scientific Awards: 2023: SNSF Consolidator Grant 2019: Heinz Maier-Leibnitz Prize (DFG), VAAM Research Prize, IUPAP Young Scientist Prize 2016: ERC Starting Grant Advising & Grants: Advises PhD and Master's students in microbiology, biophysics, and bioinformatics Secured major grants from ERC , HFSP , and DFG

• Bacterial Biofilms
• Microbial Multicellularity
• Biophysics
• +۵ مورد دیگر

Lucas Paoli is a Researcher and Course Instructor at École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. He leads the Paoli Lab (Microbiome Immunity and Ecology) within the Global Health Institute (GHI) under the School of Life Sciences (SV). His roles include scientific collaboration and teaching responsibilities in life sciences engineering. Paoli holds a PhD in Microbiome Research from ETH Zürich (2018-2023), an M.Phil. in Environmental Policy from the University of Cambridge (2017-2018), and an M.Sc. in Ecology and Evolution from École normale supérieure (2015-2017). Research Focus: His work bridges microbial immunity and ecology, investigating how microbes defend against viral infections across ecosystems like oceans and human microbiomes. Techniques include global-scale metagenomics and functional genomics to study immune strategies and ecological interactions. Key themes involve microbial community dynamics, viral defense mechanisms, and the impact of environmental factors on microbial immunity. Lab & Education: The Paoli Lab explores microbiome-immunity interactions with a focus on ecological contexts. Paoli supervises PhD students in Life Sciences Engineering. His research outputs span microbial ecology, metagenomic tool development, and marine microbiome studies. Contact: lucas.paoli@epfl.ch, AAB 1 39, +41 21 693 16 99.

• Microbiome Research
• Microbial Immunity
• Ecological Genomics
• +۴ مورد دیگر

Dr. Igor V. Pivkin is a Full Professor at the Institute of Computing within the Faculty of Informatics at the Università della Svizzera italiana (USI) in Lugano, Switzerland. His academic journey includes degrees from Novosibirsk State University (B.Sc./M.Sc. Mathematics), Brown University (M.Sc. Computer Science and Ph.D. Applied Mathematics), and postdoctoral research at MIT's Department of Materials Science and Engineering. His research focuses on multiscale/multiphysics modeling , numerical methods , and large-scale simulations of biological and physical systems. Key areas include biophysics, cellular/molecular biomechanics, stochastic modeling, and coarse-grained molecular simulations. He leverages high-performance computing (HPC) and particle-based methods to address complex biological phenomena. His work spans diverse applications, from understanding cellular mechanosensitivity and biofilm engineering to modeling cancer cell behavior and red blood cell dynamics in the spleen. His contributions bridge computational science, biotechnology, and biomedical research. He has published extensively in top-tier journals, with recent work advancing automated biofilm analysis, deep learning for microbial classification, and systems biology approaches to metal bioleaching. His lab collaborates on interdisciplinary projects, emphasizing computational innovation for real-world biological challenges.

• Multiscale Modeling
• Multiphysics Modeling
• Biophysics
• +۷ مورد دیگر

Simone Fior is a Lecturer at the Department of Environmental Systems Science , ETH Zürich , focusing on ecological genetics and plant adaptation. Their research integrates genomic, quantitative genetics, and ecological field experiments, particularly on Dianthus (Caryophyllaceae) along altitudinal and climatic gradients. Recent work explores climate-induced range shifts, local adaptation, and genomic responses to environmental changes. Professional experience includes roles at ETH Zürich since 2013 (Senior Assistant, Postdoc) and prior positions at the Edmund Mach Foundation (2009-2012) and University of Insubria (2007-2008). Education spans a PhD in Plant Biology (University of Milan, 2007) and an MSc in Natural Sciences (University of Milan, 2003). Simone co-organizes the Bioinformatics for Adaptation Genomics Winter School . Key research areas include adaptive divergence , polygenic adaptation , climate change biology , and phylogenomics . Articles emphasize genomic selection signatures, functional-structural modeling, and ecological-genetic interactions. Notable collaborations involve Jake Alexander, Alex Widmer, and interdisciplinary teams at ETH Zurich.

• Ecological Genetics
• Plant Adaptation
• Population Genomics
• +۵ مورد دیگر

Jian Peng is an Assistant Professor in the Department of Computer Science at the University of Illinois at Urbana-Champaign. His research focuses on computational biology, machine learning, and their applications to protein structure prediction, drug design, and molecular modeling. He has contributed to advancements in antibody engineering, protein-ligand docking, and generative models for biological systems. Key research areas include: Machine Learning for Molecular Modeling Protein Structure Prediction Antibody and Peptide Design Genomics and Single-Cell Analysis Structure-Based Drug Discovery His work emphasizes integrating deep learning techniques with biological datasets to address challenges in precision medicine, drug development, and systems biology. Notable achievements include developing the FastFold system to accelerate AlphaFold training and pioneering flow-based methods for antibody design. Awards include the Overton Prize (2020), recognizing contributions to computational biology. His research has been published in top journals and conferences, spanning topics from protein mutation prediction to geodesic-based immune complex modeling.

• Machine Learning
• Bioinformatics
• Computational Biology
• +۵ مورد دیگر

Dr. Andre Kahles is a Lecturer in the Department of Computer Science at ETH Zürich, specializing in biomedical informatics. His research focuses on computational methods for analyzing large-scale genomic and transcriptomic data, with applications in cancer genomics, metagenomics, and precision medicine. He has contributed to the development of tools such as SplAdder for alternative splicing analysis, MetaGraph for petascale genomic data exploration, and SECEDO for subclone detection in cancer genomes. His work bridges algorithmic innovation with biological insights, addressing challenges in single-cell analysis, genome graph alignment, and multi-omics integration. Key research themes include: Developing scalable algorithms for processing nanopore sequencing and metagenomic data Characterizing somatic mutations and non-coding drivers in cancer genomes Advancing genome graph-based alignment and annotation methods Integrating multi-omics data for clinical decision-making and tumor profiling His publications span topics like RNA-seq analysis, chromothripsis in cancers, and global urban microbiome tracking through the MetaSUB consortium. Kahles has collaborated on landmark projects including the Pan-Cancer Analysis of Whole Genomes (PCAWG) and the Tumor Profiler Study.

• Bioinformatics
• Genomics
• Cancer Genomics
• +۷ مورد دیگر

Ueli Grossniklaus is an Ordinary Professor at the University of Zurich within the Faculty of Mathematical and Natural Sciences , affiliated with the Department of Plant and Microbiology . His work focuses on plant developmental biology, particularly epigenetic and genetic mechanisms governing reproduction and adaptation. Key Courses: Epigenetics, Plant Biology Workshop, Group Seminars on Current Research Laboratory Techniques: Advanced methods in plant cell mechanics, transcriptomics, and genome editing Research Interests span plant epigenetics, reproductive biology, and the interplay between environmental stress and genetic regulation. He investigates: Mechanistic control of gametogenesis and fertilization Epigenetic contributions to plant adaptation Evolutionary implications of asexual reproduction Biophysical forces in plant cell growth Publication Trends (2025–2018) reveal expertise in: Arabidopsis and fern model systems Epigenetic regulation (DNA methylation, histone dynamics) Apomixis and hybrid seed failure mechanisms Biomechanics of pollen tubes and carnivorous plants Genome editing tools (CRISPR) and long-read sequencing Scientific Collaborations include interdisciplinary projects on: Microfluidic devices for plant cell analysis Gene drive ecology and ethics 3D imaging of plant reproductive structures Advising and Grants focus on mentoring through research internships in developmental biology, genetics, and systems biology. His lab engages in: Epigenetic response to environmental stress Cell wall mechanics in reproduction Computational modeling of plant growth Laboratory Teams integrate plant biologists, bioengineers, and computational scientists to study: Mechanistic gene regulation Evolutionary developmental biology Microrobotics for cellular force measurement

• Plant Developmental Biology
• Epigenetics
• Plant Genetics
• +۵ مورد دیگر

Professor Sebastian Hiller is a Full Professor at the Biozentrum of the University of Basel, Switzerland, where he leads a research group focused on structural biology and biophysics. His laboratory specializes in using nuclear magnetic resonance (NMR) spectroscopy to elucidate the structures and functions of proteins and their interactions at the atomic level. His research spans several key areas including molecular chaperones and protein folding mechanisms, outer membrane protein biogenesis in bacteria, and kinase signaling pathways. Notably, his group has made significant contributions to understanding how chaperones like trigger factor function, the mechanisms of outer membrane protein assembly through the Bam complex, and dynamic kinase interactions. Their work has direct implications for neurodegenerative diseases and antibiotic development. The Hiller lab's recent publications demonstrate a strong focus on NMR methodology development, protein folding dynamics, and structural mechanisms of antibiotic action. Their research on darobactin's mechanism of action against Gram-negative bacteria represents a significant advance in antibiotic discovery. The group frequently publishes in high-impact journals including Nature, Science, and Nature Communications. ICMRBS Founder's Medal (2018) EMBO Young Investigator (2014) ERC starting grant (2011) SNSF professorship (2010) SNSF scholarship for young researchers (2008) Professor Hiller supervises numerous PhD students and postdoctoral researchers, with many alumni having secured prestigious positions in academia and industry. His laboratory maintains strong collaborations across multiple institutions and has received significant funding through ERC grants and other competitive mechanisms. The Hiller group also operates advanced NMR facilities that serve the broader research community at the University of Basel.

• Structural Biology
• NMR Spectroscopy
• Protein Folding
• +۴ مورد دیگر

Prof. Enkelejda Miho is a Professor of Digital Life Sciences at the School of Life Sciences, FHNW, leading the aiHealthLab. Her work bridges computer science/AI with life sciences, focusing on drug discovery, personalized medicine, and immunology. She holds roles as Team Leader at aiHealthLab and Group Leader at the Swiss Bioinformatics Institute. Research Interests : She applies machine learning to analyze immune repertoires, antibody engineering, and autoimmunity diagnostics. Her lab develops computational tools like the RWD-Cockpit for real-world data analysis and synthetic antibody-antigen models (Absolut!) to advance biotherapeutics. Her work on dengue immunity and monoclonal gammopathies highlights translational applications. Key Projects : The aiHealthLab focuses on AI-driven diagnostics and therapeutics. Her contributions include AI frameworks for antibody specificity prediction, age-related immune repertoire changes, and large-scale network analysis of antibody repertoires. Labs/Teams : Leads aiHealthLab and collaborates with the Swiss Bioinformatics Institute, integrating computational and experimental immunology.

• Digital Life Sciences
• Medical Informatics
• Artificial Intelligence in Healthcare
• +۴ مورد دیگر

Dr. Sung Sik Lee serves as a Lecturer in the Department of Materials at ETH Zurich, Switzerland. Affiliated with ScopeM (Scientific Center for Optical and Electron Microscopy), he develops microfluidic platforms for real-time cellular analysis at the HPM C 52.2 facility (Otto-Stern-Weg 3, Zürich). His research bridges engineering and biology to investigate cellular responses to mechanical and chemical stimuli. His primary research domains include: Microfluidics : Design of microfabricated devices for cell stretching, particle separation, and dynamic stimulation Cellular Aging : Mechanisms of chromosome loss and nuclear pore complex reorganization in yeast models Nanotoxicology : Impact of nanoplastics on macrophage inflammation and intestinal barrier integrity Advanced Imaging : Application of holotomography and Raman spectroscopy for label-free cellular analysis His work consistently targets translational applications in disease modeling and diagnostics. Analysis of his 50+ publications reveals strong interdisciplinary integration, particularly the convergence of machine learning with microscopy (e.g., automated vacuole quantification in yeast) and the development of open-access resources like MicrobioRaman. Recent trends emphasize nanoparticle-cell interactions and microfluidic solutions for inflammatory conditions including IBD and acute kidney injury. Dr. Lee actively contributes to ScopeM's mission of advancing microscopy techniques, maintaining collaborations across ETH Zurich's research ecosystem. His laboratory focuses on microfluidic device fabrication, cellular mechanotransduction studies, and biophysical characterization of particles and cells, with ongoing projects extending through 2025.

• Microfluidics
• Cell Biology
• Biophysics
• +۴ مورد دیگر

Prof. Dr. Marek Basler is an Associate Professor of Infection Biology at the Biozentrum, University of Basel , leading a research group focused on the Type VI Secretion System (T6SS) in bacterial pathogens. His work bridges structural biology, molecular microbiology, and computational analysis to unravel the mechanisms of this contractile nanomachine. PhD in Microbiology (2007, Institute of Microbiology, CAS, Prague) Postdoctoral Fellow (2007–2013, Harvard Medical School) Assistant Professor (2013–2018) and Associate Professor (since 2018) at Biozentrum His research explores the structure, assembly, and therapeutic potential of the T6SS, a critical virulence factor in pathogens like Pseudomonas aeruginosa . Key themes include bacterial defense strategies , intermicrobial competition , and host-pathogen interactions . Recent projects highlight T6SS roles in antibiotic resistance and horizontal gene transfer . The most recent publications (2025–2024) reveal novel insights into T6SS activation by environmental stress , toxin diversity , and host cell targeting . Trends span microbial ecology , nanomachine dynamics , and computational modeling of bacterial interactions. Scientific Awards : EMBO Membership (2023) ERC Consolidator Grant (2019) EMBO Gold Medal (2018) Friedrich Miescher Award (2018) EMBO Young Investigator (2015) His lab (Basler Lab) utilizes state-of-the-art microscopy , biochemical techniques , and live-cell simulations (e.g., BacFighT6 ). Collaborations span institutions like Harvard Medical School and NCCR-AntiResist , with future work targeting antibacterial therapies .

• Type VI Secretion System (T6SS)
• Bacterial Virulence
• Structural Biology of Nanomachines
• +۵ مورد دیگر

Sara Magliacane is an Assistant Professor at the University of Amsterdam and a Research Scientist at the MIT-IBM Watson AI Lab . She leads research at the intersection of causality and machine learning , focusing on improving AI robustness, generalization, and safety through causal reasoning. Her work spans causal representation learning , causal discovery , and causality-inspired ML in domains like reinforcement learning and dynamical systems. PhD in Artificial Intelligence (2017), VU Amsterdam MSc in Computer Engineering (2011), Politecnico di Milano/Torino BSc in Computer Engineering (2008), Università degli Studi di Trieste Her research explores causal variable identification from high-dimensional data (e.g., images, sequences) and causal graph discovery for domain adaptation. Methods include CITRIS , FANS-RL , and SNAP , with applications in embodied AI and biomedical data. The group emphasizes theoretical guarantees and scalable algorithms for real-world systems. Recent work trends include temporal causal modeling , intervention-efficient learning , and nonstationary reinforcement learning . Publications cover topics like causal discovery in partially observed settings , causal graph pruning , and sample-efficient concept learning , often combining neurosymbolic approaches with deep learning. Scientific Awards : ELLIS Scholar Sara supervises PhD students across universities (UvA, University of Pisa) and collaborates with institutions like TU Delft , Harvard , and IBM Research . She co-organizes workshops at premier conferences (NeurIPS, ICML, AISTATS) and teaches causality courses at the University of Amsterdam and Harvard Data Science Initiative. Her lab, Amsterdam Machine Learning Lab (AMLab) , investigates causal structure in embodied agents , safe reinforcement learning , and hybrid dynamical system modeling . The group maintains active partnerships with institutions such as MIT-IBM Watson AI Lab , Qualcomm , and Adyen .

• Causality
• Causal Representation Learning
• Causal Discovery
• +۴ مورد دیگر