معرفی
Dr. Sung Sik Lee serves as a Lecturer in the Department of Materials at ETH Zurich, Switzerland. Affiliated with ScopeM (Scientific Center for Optical and Electron Microscopy), he develops microfluidic platforms for real-time cellular analysis at the HPM C 52.2 facility (Otto-Stern-Weg 3, Zürich). His research bridges engineering and biology to investigate cellular responses to mechanical and chemical stimuli.
His primary research domains include:
- Microfluidics: Design of microfabricated devices for cell stretching, particle separation, and dynamic stimulation
- Cellular Aging: Mechanisms of chromosome loss and nuclear pore complex reorganization in yeast models
- Nanotoxicology: Impact of nanoplastics on macrophage inflammation and intestinal barrier integrity
- Advanced Imaging: Application of holotomography and Raman spectroscopy for label-free cellular analysis
Analysis of his 50+ publications reveals strong interdisciplinary integration, particularly the convergence of machine learning with microscopy (e.g., automated vacuole quantification in yeast) and the development of open-access resources like MicrobioRaman. Recent trends emphasize nanoparticle-cell interactions and microfluidic solutions for inflammatory conditions including IBD and acute kidney injury.
Dr. Lee actively contributes to ScopeM's mission of advancing microscopy techniques, maintaining collaborations across ETH Zurich's research ecosystem. His laboratory focuses on microfluidic device fabrication, cellular mechanotransduction studies, and biophysical characterization of particles and cells, with ongoing projects extending through 2025.
