معرفی
Gabriel Neurohr serves as Assistant Professor in the Department of Biology at ETH Zurich, Switzerland, where he leads research on the physiological consequences of cell size dysregulation. His work bridges fundamental cell biology with implications for aging and cancer, investigating how deviations from species-specific cell size norms disrupt cellular homeostasis.
Academic training includes a BSc in Biochemistry from ETH Zurich (2003-2006), PhD at Barcelona's Center for Genomic Regulation (2008-2012), and postdoctoral fellowship at MIT's Koch Institute (2013-2020). His research program addresses four core questions: (1) functional size limits of cells, (2) size-senescence relationships, (3) macromolecule-volume coordination, and (4) density-dependent functional impacts, employing genetic, live-imaging, and computational approaches in yeast and mammalian systems.
Recent publications reveal a methodological evolution toward quantitative analysis, with machine-learning-enhanced imaging (2023) complementing mechanistic studies linking genome instability to size-induced senescence (2023). His 2024 work establishes cell enlargement as a primary driver of senescence through cytoplasmic dilution and organelle dysfunction, demonstrating conserved principles across eukaryotes.
Major recognitions include:
- SNF Eccellenza Fellowship (2020-2025)
- EMBO Long Term Fellowship (2013-2014)
- ETH Medal for Master's excellence (2008)
Neurohr's lab develops innovative tools like holotomography-based vacuole quantification while maintaining focus on fundamental size-regulation mechanisms. He teaches advanced courses on biomolecular condensates and cellular matter properties, mentoring through ETH's structured graduate programs. Current work explores therapeutic targeting of size-dependent senescence pathways in age-related diseases.
