جست‌وجوی استاد و پژوهشگر

Brian Oxhornمشاهده پروفایل

دانشیار

• Nursing Education
• Healthcare Administration
• Nursing Simulation
• +۳ مورد دیگر

Brian Oxhorn, PhD, MSN, RN is the Dean and Associate Professor at Roseman University's College of Nursing. Prior roles include Director of the Simulation and Skills Laboratory (2012–present) and Assistant Professor (2012–2015). His career spans critical care nursing, emergency nursing, and academic administration. He holds a BS in Nursing (1992, University of Nevada-Reno), PhD in Pharmacology (2002, same institution), and a postdoctoral fellowship at the University of Connecticut (2003). His MSN in Nursing Education was earned at Drexel University (2005). Dr. Oxhorn's research focuses on nursing education innovation, simulation-based training, and healthcare administration. Key areas include: Development of high-fidelity simulation curricula for mental health competencies Pharmacology-driven signaling pathways in endothelial cells Policy analysis in health systems management His publications emphasize simulation efficacy (e.g., 2016 study on mental health skills) and foundational pharmacology work on caspase signaling (2001–2003). Presentations highlight simulation implementation strategies in nursing education. Awards include the 2003 George G. Bierkamper Outstanding Pharmacology Graduate Student Award. Leadership roles span AACN (2012–present), Nevada State Grassroots Liaisons (2022–present), and multiple national nursing organizations. Advising contributions include collaborative work on simulation studies. His Simulation and Skills Laboratory at Roseman supports innovative clinical training methodologies.

Hamid Akbarshahiمشاهده پروفایل

دانشیار

• Respiratory Immunopharmacology
• Asthma Exacerbation Mechanisms
• Viral-Induced Inflammation
• +۳ مورد دیگر

Hamid Akbarshahi is an Associate Professor and Researcher in Respiratory Medicine at Lund University. He leads the Respiratory Immunopharmacology Research team and supervises research in Translational Respiratory Medicine. His work focuses on asthma exacerbation mechanisms, viral-induced inflammation, and allergen interactions in airways. Research Interests: His studies explore cytokine regulation (IL-33, IL-1β), TLR signaling pathways, and the impact of house dust mite (HDM) and rhinovirus interactions on airway inflammation. He investigates lung transplantation outcomes, particulate matter effects on cardiovascular systems, and translational models of asthma/COPD exacerbations. Collaborations: Active collaborations span immunology, pulmonology, and environmental health. Recent projects include studying ECMO-supported lung transplants and PM2.5-induced neuroinflammation. Awards: No specific awards listed, but his work contributes to UN SDGs 3 (Good Health) and 11 (Sustainable Cities). Grants/Projects: Supervises 3 ongoing projects including MECRIS (mediastinal cryobiopsy studies), statin/bisphosphonate effects on pulmonary fibrosis, and immune mechanisms in SARS-CoV-2/asthma interactions.

Erin Cramمشاهده پروفایل

دانشیار

• Cell Biology
• Mechanotransduction
• Cell Migration
• +۳ مورد دیگر

Erin Cram is the Associate Dean for Research and an Associate Professor in the Department of Biology at Northeastern University's College of Science. She holds leadership roles in strategic research planning, grant support, and fostering interdisciplinary collaboration. Her research focuses on cell migration and mechanotransduction in Caenorhabditis elegans , particularly how mechanical forces influence cell behavior and tissue function. She collaborates with Chemical Engineers to enhance drug compound production in Catharanthus roseus . Dr. Cram earned her BS in Biology from UNC Chapel Hill, a PhD in Molecular Cell Biology from UC Berkeley, and completed postdoctoral studies at Princeton University. She is committed to mentoring early-career faculty and advancing student research excellence through roles like Director of Graduate Studies in Biology. Her work bridges cell biology and engineering, with notable contributions to understanding reproductive system mechanics and plant biotechnology. Her lab's innovations include developing imaging tools and protocols for mechanotransduction studies. Education: Bachelor's of Science in Biology, University of North Carolina, Chapel Hill PhD in Molecular Cell Biology, University of California, Berkeley Postdoctoral Studies in Cell Migration, Princeton University Research Interests: Dr. Cram explores how cells sense and respond to mechanical forces, particularly in C. elegans reproductive tissues. Her work integrates live imaging, genetic approaches, and engineering collaborations to study cytoskeletal dynamics, calcium signaling, and contractility. Key areas include: Actomyosin network organization Calcium-mediated cell communication Plant-based pharmaceutical production Awards and Grants: Notable funding includes an NSF grant (2015) for Catharanthus roseus research and collaboration with the Institute for Chemical Imaging of Living Systems. Her work emphasizes interdisciplinary approaches to address biomedical challenges. Lab & Teams: The Cram Lab collaborates with bioengineers and international groups (e.g., Tel Aviv University) to advance mechanobiology and biomedical engineering. They prioritize training students in cutting-edge techniques like CRISPR and live-cell imaging.

• Molecular Pharmacology
• Respiratory System
• Cell Biology
• +۸ مورد دیگر

Dr. Hoeke Baarsma is a Lecturer in the Department of Pharmacy at the University of Groningen's Faculty of Science and Engineering. His research focuses on Molecular Pharmacology with an emphasis on respiratory system mechanisms, chronic diseases, and aging. He investigates the role of Wnt signaling pathways in lung physiology and pathology, particularly in conditions like COPD and idiopathic pulmonary fibrosis. His work also explores the effects of air pollutants and inflammatory responses in pulmonary systems. Baarsma has contributed to studies on drug repurposing (e.g., amlexanox) and in vitro models (e.g., 3D spheroids) for lung pathology research. He is actively involved in educational committees and program leadership in Pharmacy and Pharmaceutical Science. Research Interests: Molecular Pharmacology, Respiratory System Biology, Wnt Signaling Pathways, Chronic Lung Diseases, Air Pollution Effects, and Drug Development. His publications span over 36 peer-reviewed articles, focusing on mechanisms of lung inflammation, fibrosis, and regeneration. Baarsma holds ancillary roles as owner of H.A.Baarsma Beheer BV, complementing his academic activities.

Mikael Adnerمشاهده پروفایل

مدرس ارشد

• Respiratory Medicine
• Allergy
• Asthma
• +۳ مورد دیگر

Mikael Adner is a Senior Lecturer at the Karolinska Institutet , affiliated with the Institute of Environmental Medicine and leading the Unit of Experimental Asthma and Allergy Research. His work bridges physiology, pharmacology, and molecular immunology to uncover mechanisms behind asthma-related airway constrictions. Senior Lecturer, Karolinska Institutet (2021–present) Docent, Karolinska Institutet (2006) Research Focus: Respiratory Medicine & Allergy Research interests center on asthma pathophysiology , emphasizing: Mast cell activation and its role in airway inflammation Cytokine signaling (e.g., IL-13, IL-33, TLR pathways) Lipid mediator metabolism and its impact on bronchoconstriction Development of guinea pig and human bronchi models for translational studies Novel bronchodilators (quinolines, polyvinylalcohol-carbazate) Mechanisms of DNA damage in respiratory epithelium His recent publications highlight trends in allergic inflammation , with studies on: TLR activation and airway hyperresponsiveness Mast cell heterogeneity via single-cell RNA sequencing COVID-19-induced metabolic changes Targeting oxylipins for asthma treatments Anti-inflammatory properties of chemical compounds Role of serotonin and cytokines in airway responses Collaborations include researchers from multiple institutions, with a focus on translational asthma research using in vivo , ex vivo , and in vitro approaches. Current projects aim to identify new therapeutic targets for asthma and allergic diseases.

Charalambos Papaxanthisمشاهده پروفایل

استاد

• Neuroscience
• Motor Control
• Motor Learning
• +۵ مورد دیگر

Charalambos Papaxanthis is a Professor and Director of the CAPS Laboratory (UMR INSERM 1093) at the University of Burgundy's Faculty of Sport Sciences (UFR Staps). His research focuses on motor control, cognitive neuroscience, and sensorimotor integration, particularly under altered gravitational conditions. He holds advanced degrees from the University of Burgundy, including a 1998 PhD and 2004 habilitation in neuroscience. His work employs methods such as 3D motion analysis, EMG, TMS, and computational models to explore how the brain processes motor tasks and integrates gravity. Key themes include motor learning through mental imagery and observation, and neurorehabilitation applications. He leads studies like the IMPROVE trial investigating muscle vibrations' role in stroke recovery. His lab (CAPS) is part of INSERM, emphasizing translational research in health and motor performance.

• Proteomics
• Cancer Biology
• Mitochondrial Biology
• +۳ مورد دیگر

Dr. Achim Treumann is a Researcher at Newcastle University with a primary focus on proteomics, molecular biology, and disease mechanisms. His work spans cancer biology, mitochondrial function, platelet biology, and stress responses in diverse biological systems. Research Focus: Dr. Treumann employs advanced proteomic techniques to investigate: Molecular mechanisms in cancer progression (e.g., receptor signaling, ubiquitination, platelet-tumor interactions) Mitochondrial biology and its relationship to aging/longevity Proteomic biomarker discovery for neonatal diseases and plant stress responses Development of novel mass spectrometry methodologies His recent publications (2013-2019) demonstrate consistent productivity in high-impact areas including oncology, stem cell biology, and cardiovascular proteomics, utilizing techniques like SWATH-MS, SILAC, and pathway analysis.

James Brownمشاهده پروفایل

عضو هیئت علمی

• Pharmacology
• Gastroenterology
• Nitric Oxide Biology
• +۵ مورد دیگر

Dr. James Brown is a Principal Lecturer at the School of Medicine, Pharmacy and Biomedical Sciences (Faculty of Science & Health) at the University of Portsmouth , United Kingdom. He is affiliated with the Institute of Life Sciences and Healthcare and Centre for Integrated Health and Wellbeing . His research focuses on Gastroenterology , Cannabinoid Pharmacology , and Nitric Oxide Biology , with a particular emphasis on endoscopic procedures and gastrointestinal motility disorders. Research Interests: Role of cannabinoids in health and disease Medical applications of nitric oxide Endoscopic techniques for neoplasia detection Intestinal motility and ion channel regulation Colon-specific drug delivery systems Publication Trends: His recent articles (2017-2024) focus on disposable endoscopy technologies, cannabinoid effects on smooth muscle, virtual chromoendoscopy for colitis surveillance, and drug delivery innovations. Key subfields include endoscopic imaging, inflammatory bowel disease, TREK-1 channel therapeutics, and nitric oxide's role in gastrointestinal function. Academic Leadership: Dr. Brown accepts PhD students and has been a principal investigator on projects related to endoscopy, cannabinoids, and inflammatory bowel disease. His work appears in major journals like Gut , Endoscopy , and British Journal of Pharmacology , with multiple international collaborations.

• Cardiovascular Development
• Transcriptional Regulation
• Smooth Muscle Biology
• +۳ مورد دیگر

Michael S. Parmacek, MD serves as Chair of the Department of Medicine and holds the Frank Wister Thomas Professorship at the University of Pennsylvania's Perelman School of Medicine. His clinical practice is affiliated with the Hospital of the University of Pennsylvania. Dr. Parmacek completed his medical education at Northwestern University Feinberg School of Medicine, followed by residency at University of Michigan Medical Center and multiple fellowships at Northwestern Medical Center, Howard Hughes Medical Institute, and University of Michigan Medical Center. His extensive training established foundations in cardiovascular medicine and molecular research. Medical School: Northwestern University Feinberg School of Medicine Residency: University of Michigan Medical Center Fellowships: Northwestern Medical Center, Howard Hughes Medical Institute, University of Michigan Medical Center His research focuses on transcriptional regulation in cardiovascular development, particularly the role of myocardin family proteins in smooth muscle biology and heart development. Current investigations explore BMP signaling pathways, stem cell differentiation mechanisms, and vascular disease pathogenesis. His work bridges basic molecular mechanisms with clinical applications in congenital heart defects and vascular remodeling disorders. Analysis of his publication record reveals consistent contributions to understanding cardiac development and vascular biology, with recent emphasis on pulmonary cyst formation, airway remodeling in asthma, and epigenetic regulation of cardiomyocyte differentiation. His research demonstrates integration of genetic, molecular, and physiological approaches to address fundamental questions in cardiovascular medicine. Dr. Parmacek maintains active research collaborations across multiple institutions, with publications appearing in high-impact journals including Nature Cell Biology, Journal of Clinical Investigation, and Circulation Research. His leadership extends to editorial roles and participation in national research initiatives. He mentors junior faculty and researchers while directing departmental research strategy. His laboratory employs cutting-edge techniques in molecular biology, genetic engineering, and physiological assessment to investigate cardiovascular development and disease mechanisms. Current projects include studies of transcriptional networks in vascular smooth muscle and their implications for therapeutic interventions.

• Mitochondrial Genetics
• Neurodegenerative Diseases
• Genetic Variants and Disease
• +۶ مورد دیگر

AURORA GOMEZ DURAN is a Ramón y Cajal contract researcher at the University of Santiago de Compostela (USC), affiliated with the Department of Biochemistry and Molecular Biology and the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS). She leads the MeMoEn research group focusing on molecular mechanisms of disease, particularly mitochondrial genetics and its role in neurodegeneration and late-onset disorders. Her work bridges population genetics, pharmacogenomics, and clinical applications, emphasizing mitochondrial DNA (mtDNA) variants' impact on disease risk and pathophysiology. Dr. Gomez Duran holds a PhD from the University of Zaragoza (2012), where her thesis explored genetic variants of mtDNA from population genetics to pharmaceutical genomics under the supervision of Dr. Eduardo Ruiz-Pesini. Her research integrates single-cell analysis, genomic sequencing (including Oxford Nanopore), and in vivo models to study mitochondrial dysfunction in aging, neurodegenerative diseases, and metabolic disorders. Key contributions include identifying mtDNA heteroplasmy's role in aging biomarkers and developing protocols for CpG methylation detection in mtDNA. Her publications highlight studies on cryptic mtDNA mutations in mid-to-late life, mitophagy's anti-inflammatory role, and genotype-phenotype associations in large cohorts like the UK Biobank. She has also explored therapeutic strategies such as cysteine supplementation for mitochondrial translation deficiencies and read-through therapy for mtDNA nonsense mutations. While no specific awards are listed, her work has advanced mitochondrial pharmacogenomics and personalized medicine approaches. Dr. Gomez Duran collaborates on projects investigating mitochondrial dysfunction in liver failure, antibiotic therapy optimization via mtDNA profiling, and mitochondrial-nuclear interactions in disease. Her interdisciplinary approach spans biochemistry, genetics, and clinical research, positioning her at the forefront of mitochondrial medicine.

Ripla Aroraمشاهده پروفایل

استادیار

• Reproductive Biology
• Developmental Biology
• 3D Imaging Analysis
• +۳ مورد دیگر

Ripla Arora is an Assistant Professor in the Cell & Molecular Biology Program and Genetics & Genome Sciences Program at Michigan State University. Her research focuses on understanding how hormones influence uterine 3D architecture to modulate embryo implantation and pregnancy success. She employs techniques such as classic embryology, developmental genetics, 3D imaging, and computational analysis to study maternal-fetal interactions. Key research interests include uterine gland development, hormonal regulation mechanisms, and the interplay between progesterone and reproductive processes. Her work integrates advanced imaging technologies with molecular biology approaches to unravel structural-functional relationships in the uterus. Recent publications highlight her contributions to understanding Tbx4-related pulmonary hypertension, endometrial stromal cell contributions to fertility, and the role of signaling pathways like YAP1/WWTR1 in pregnancy initiation. Her studies bridge developmental biology and clinical applications, with implications for fertility and pregnancy complications. No scientific awards are explicitly listed in the provided text. Her research group, the Arora Lab, actively investigates uterine architecture using multidisciplinary methods.

Andreea Tracheمشاهده پروفایل

دانشیار

• Experimental Biophysics
• Biomechanics
• Cell Biology
• +۳ مورد دیگر

Dr. Andreea Trache is an Associate Professor in the Department of Medical Physiology and Biomedical Engineering at Texas A&M University. She holds affiliations within the School of Medicine and the Department of Biomedical Engineering. Her research focuses on cellular responses to mechano-chemical stresses, integrating physics, engineering, and biology to study live cell dynamics, intracellular signaling, and mechanotransduction. Her lab develops advanced microscopy techniques, including atomic force microscopy and total internal reflection fluorescence (TIRF) microscopy, to observe real-time cellular behavior in response to mechanical forces. Dr. Trache's education includes a B.S. in Physics from the University of Bucharest (1989) and a Ph.D. in Physics from the Institute of Atomic Physics, Romania (1996). She has been recognized with the National Science Foundation CAREER Award for her innovative work. Her research interests span experimental biophysics, biomechanics, and vascular physiology, particularly emphasizing live vascular cells as models to study mechanosensing and adhesion dynamics. Key research themes include understanding how mechanical forces influence cell behavior, such as contraction, migration, and adhesion. Her lab investigates the molecular mechanisms behind cytoskeletal force balance and the role of integrins in mechanotransduction. Techniques like single-cell imaging under mechanical stimulation are central to her work, revealing transient biological events masked in macroscopic studies. Lab members include Malea Murphy (PhD, Research Specialist) and Samuel V. Padgham (Technician III). Dr. Trache’s publications span vascular aging, atherosclerosis mechanisms, and the development of microscopy tools for mechanobiology. Her work bridges fundamental biophysical principles with translational applications in cardiovascular health and disease.

• Reproductive Biology
• Preterm Labor Mechanisms
• Uterine Contractility
• +۴ مورد دیگر

Heather Burkin, Ph.D., is an Associate Professor in the Department of Pharmacology at the University of Nevada, Reno, where she leads an active research program focused on the molecular mechanisms governing uterine contractility and the pathophysiology of preterm labor. Education B.A. in Biology, University of Colorado, Boulder Ph.D. in Animal Sciences (Reproductive Biology), University of Illinois, Urbana Research Interests Dr. Burkin’s laboratory investigates the cellular and molecular factors that regulate the onset of labor, with the overarching goal of reducing neonatal morbidity linked to spontaneous preterm birth. Using state-of-the-art tissue-engineering approaches, her team creates synthetic three-dimensional myometrial tissue models that replicate both normal and pathological pregnancy conditions. Central to her work is the study of matrix metalloproteinases—particularly MMP-2 and MMP-9—and their roles in modulating uterine contractility via remodeling of the extracellular matrix and intracellular signaling cascades. Additional foci include the impact of maternal obesity on long-term childhood respiratory outcomes and the nitric-oxide-mediated pathways that govern myometrial quiescence and activation. Publication Trends Across her extensive publication record, a clear trajectory emerges: from early molecular characterizations of gamete recognition and integrin biology to a concentrated emphasis on the biochemical underpinnings of preterm labor. Recent works highlight translational strategies—pharmacological inhibition of MMP-9, prostaglandin-driven contractility testing in engineered tissues, and epidemiological analyses linking maternal BMI to childhood asthma—demonstrating an integrative approach that bridges bench discoveries to potential clinical interventions. Scientific Awards No specific awards or honors are listed in the provided text. Current Funding & Collaborative Networks The text does not enumerate active grant numbers or named trainees; however, the sustained output in high-impact journals and the development of sophisticated tissue-engineering platforms suggest robust extramural funding and interdisciplinary collaborations across reproductive biology, pharmacology, and biomedical engineering. Laboratory & Facilities Dr. Burkin directs a laboratory equipped for integrative reproductive sciences, integrating cell-culture suites, biomechanical stretch systems, mass-spectrometry proteomics, and 3-D bioprinting capabilities to create and validate synthetic myometrial constructs.

• Biochemistry
• Molecular Biology
• Muscle Biology
• +۴ مورد دیگر

Patricia Ellison is a Teaching Professor in the Department of Molecular Biosciences at the University of Nevada, Reno. Her work centers on the regulation of smooth muscle myosins via phosphorylation and dephosphorylation, as well as their interactions with actin and regulatory enzymes like myosin light chain kinase and phosphatase. Education B.S., 1983, University of Sheffield, England Ph.D., 1987, University of Sheffield, England Research Interests Dr. Ellison’s research investigates the biochemical mechanisms underlying smooth muscle contraction, with a focus on enzyme dynamics and protein interactions. Her expertise spans molecular regulation, enzymology, and cellular biomechanics. Contact Phone: (775) 784-4561 (Office); (775) 771-1398 (Mobile) Email: ellison@unr.edu Location: Building HMS, Room 146B Mail Stop: 330

• Cardiac Physiology
• Vascular Biology
• Autonomic Nervous System
• +۳ مورد دیگر

Nathan Grainger serves as a Research Assistant Professor in the Department of Physiology and Cell Biology at the University of Nevada, Reno, where his laboratory investigates fundamental mechanisms of pacemaker function in cardiac and urinary systems. His academic credentials include a B.Sc. in Neuroscience from the University of Manchester, United Kingdom, and a Ph.D. in Cellular and Molecular Pharmacology and Physiology from the University of Nevada, Reno. Dr. Grainger's primary research explores the autonomic regulation of sinoatrial node vasculature, energy metabolism in pacemaker cells, and pathophysiological mechanisms in heart failure. His work bridges cardiac electrophysiology and vascular biology, with significant focus on microvascular rarefaction, mitochondrial-sarcoplasmic reticulum interactions, and regional heterogeneity in nodal tissue. Additionally, he investigates peristaltic pacemaker mechanisms in the renal pelvis, examining ion channel dynamics and interstitial cell function. Analysis of his 15 most recent publications reveals a cohesive research trajectory centered on pacemaker dysfunction across organ systems. His cardiac studies predominantly address sinoatrial node vulnerability in heart failure (including HFpEF), while urological work emphasizes Ca 2+ -activated chloride channels and T-type calcium channels in urinary tract pacemaking. This dual focus demonstrates how cellular energy regulation and vascular control mechanisms underlie rhythmicity in both heart and urinary systems. Dr. Grainger leads an active research laboratory utilizing advanced techniques including vibratome sectioning for live imaging of intact pacemaker regions, molecular channel analysis, and metabolic studies. His team develops innovative approaches to isolate and characterize pacemaker tissues while investigating translational implications for heart failure and urinary motility disorders.