جستجوی استاد راهنمای دانشگاهی

• Biological Sciences
• Medical Research
• Public Health
• +۳ مورد دیگر

Dr. Courtney Judkins is a Research Officer at La Trobe University, affiliated with the Department of Microbiology, Anatomy, Physiology & Pharmacology. Her research focuses on cardiovascular disease mechanisms, atherosclerosis, and the interplay between oxidative stress and genetic factors in disease progression. She has expertise in biomedical research methodologies, including animal models and epidemiological studies. Her work spans topics such as the role of NOX enzymes in vascular dysfunction, genetic influences on cardiovascular outcomes (e.g., ApoE knockout mice), and clinical epidemiology of cardiovascular risk factors in specific populations (e.g., elderly patients and those with Down syndrome). She collaborates widely with researchers in pharmacology, cardiology, and public health. Key contributions include investigating appendectomy's cardiovascular effects in elderly populations, the dual roles of NOX2 in atherosclerosis, and the impact of aldosterone on hypertension via immunological pathways. Her research integrates molecular, physiological, and population-level analyses to advance understanding of cardiovascular pathophysiology. Dr. Judkins has published extensively in high-impact journals like the New England Journal of Medicine and Scientific Reports, with a focus on translating basic science findings into clinical insights. Her work emphasizes translational research to improve cardiovascular health outcomes and public health strategies.

Susan Chalmersمشاهده پروفایل

مدرس ارشد

• Mitochondrial Biology
• Calcium Signaling
• Neurodegeneration
• +۷ مورد دیگر

Susan Chalmers is a Senior Lecturer at the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, within the Faculty of Science. She is also a Chancellors Research Fellow, with a strong focus on mitochondrial function in brain and vascular cells. Her work bridges neuroscience, pharmacology, and cellular physiology. Education: BSc (Hons) in Biological Sciences, University of Aberdeen PhD, jointly awarded by the University of Dundee and the Buck Institute for Age Research, CA Fellow of the Higher Education Academy Her research centers on mitochondria, particularly their role in calcium signaling, neurodegeneration, and disease mechanisms such as those in Alzheimer’s and diabetes. She employs advanced live-cell fluorescence imaging techniques to study mitochondrial motility and functionality in neurons, glia, and vascular cells. Her current projects examine the impact of amyloid-β and hyperglycaemia on mitochondrial dynamics. The most recent publications reflect a dual focus: (1) mitochondrial regulation of calcium signaling in vascular and neuronal systems, and (2) patient-centered research in breast cancer through public engagement and storytelling. These works span physiology, pharmacology, and health sciences, demonstrating interdisciplinary impact. Scientific Recognition and Service: University representative, The Physiological Society External Examiner for BSc, MSci, and MSc programs Active participant in ARUK and Scottish Neuroscience events Contributor to patient engagement initiatives in oncology Susan supervises 2 PhD and 2 EngD students, and hosts multiple Masters-level research projects. She is the course coordinator for the MSc Neuroscience & Mental Health and module coordinator for the MPharm Management of Cardiovascular Conditions. She has secured significant research funding, including grants from ARUK and EPSRC, as both Principal and Co-investigator. Her lab specializes in primary cell culture, live-cell imaging (Ca²⁺, ROS, organelle transport), and quantitative image analysis, contributing to both fundamental and translational research in neurovascular health.

• Smooth Muscle Physiology
• Calcium Signaling
• Reproductive System
• +۳ مورد دیگر

Ping Lu, PhD is an Instructor in the Department of Microbiology at UMass Chan Medical School, specifically affiliated with the T.H. Chan School of Medicine. Their research focuses on the physiology and pathophysiology of smooth muscle using advanced technologies including molecular biology, gene editing, calcium imaging, organ culture, and transgenic animal models. Education: BS in Animal Science from Huazhong Agricultural University, Wuhan, China MS in Biology from Zhejiang University, Hangzhou, China PhD in Biology from Zhejiang University, Hangzhou, China Ping Lu's research primarily centers on smooth muscle physiology, with particular emphasis on calcium signaling mechanisms in various smooth muscle tissues including the internal anal sphincter, uterine tissue, and airway smooth muscle. Their work explores the role of ion channels such as TMEM16A in generating electrical and calcium signals that regulate smooth muscle tone and contraction. A significant portion of their research investigates the unexpected presence and function of taste receptors (particularly bitter taste receptors) in reproductive tissues and their potential as therapeutic targets for conditions like preterm labor. Analysis of Dr. Lu's publication history reveals a strong focus on the molecular mechanisms underlying smooth muscle function across different organ systems. Their most recent work (2023-2024) continues to explore TMEM16A channels in gastrointestinal and reproductive tissues, while also investigating how bitter taste receptors might be leveraged for therapeutic interventions. Earlier work (2016-2021) established foundational knowledge about calcium oscillations in uterine peristalsis and the role of various ion channels in smooth muscle tone regulation across multiple systems including gastrointestinal, reproductive, and respiratory tissues. Dr. Lu frequently collaborates with Dr. Ronghua ZhuGe and other researchers at UMass Chan Medical School, with a consistent publication record spanning nearly two decades from 2004 to the present. Their work bridges basic cellular physiology with potential clinical applications, particularly in reproductive health and gastrointestinal disorders.

Lavannya Mundayatil Panditمشاهده پروفایل

دانشیار

• Pulmonary Hypertension
• Pulmonary and Critical Care Medicine
• Molecular Mechanisms of Pulmonary Vascular Diseases

Dr. Lavannya M. Pandit is an Associate Professor (tenure-track) at Baylor College of Medicine and full-time staff physician at the Michael E. DeBakey Veterans Affairs Medical Center . She serves as Director of the DeBakey Pulmonary Hypertension Program and is a core faculty member at the Center for Translational Research on Inflammatory Diseases (CTRID) . Education: BS in Biology and History from Yale University (1996) MD from University of Texas Southwestern Medical School (2000) Residency in Internal Medicine at University of Iowa Hospitals and Clinics (2003) Fellowship in Pulmonary and Critical Care at Baylor College of Medicine (2008) Her research focuses on the physiologic and molecular mechanisms of pulmonary vascular diseases , particularly pulmonary arterial hypertension (PAH) and COPD. Key areas include potassium channel dysfunction, rho-kinase signaling, vascular remodeling, and exosome-mediated pathogenesis. She has published extensively in journals like NEJM , Hypertension , and British Journal of Pharmacology . Current research projects include studies on COPD biomarkers , anatomic microniches in PAH , and smooth muscle cell biology in pulmonary vasculopathy. Her work is funded by multiple VA grants, including a CAREER DEVELOPMENT AWARD and two active investigator-initiated grants ( Neutrophilic exosomes in COPD and Translational research on vascular remodeling ). Scientific Awards: VA Career Development Award (2013-2018)

Michael Parrishمشاهده پروفایل

دانشیار بالینی

• Pharmacology
• Physiology
• Gastroenterology
• +۳ مورد دیگر

Michael Parrish serves as an Associate Clinical Professor within the Department of Anesthesia at the Michael G. DeGroote School of Medicine, McMaster University. His academic profile is maintained in the McMaster Experts system, with contact details including phone extension 75171 and email parrim@mcmaster.ca. Dr. Parrish's research focuses on gastrointestinal pharmacology and neurophysiology, specializing in tachykinin and NK1 receptor mechanisms in canine ileum tissue. His work examines contractile responses, prostaglandin release pathways, and neurotransmitter interactions relevant to gastrointestinal motility disorders and neurogastroenterology. His scholarly output centers on two pivotal 1994-1995 publications analyzing receptor-mediated responses in gastrointestinal tissue. These studies established foundational insights into eicosanoid signaling and smooth muscle pharmacology, though McMaster Experts records zero publications in the last decade indicating a shift from active research.

Edwin Mooreمشاهده پروفایل

استاد

• Cardiac Physiology
• Excitation-Contraction Coupling
• Calcium Signaling
• +۳ مورد دیگر

Dr. Edwin Moore is Professor and Head of the Department of Cellular and Physiological Sciences at the University of British Columbia Faculty of Medicine. His research focuses on excitation-contraction coupling mechanisms in cardiac and smooth muscle cells. B.Sc. and M.Sc. in Physiology from the University of Toronto Ph.D. in Pharmacology from the Mayo Clinic Research Interests: Dr. Moore's laboratory investigates the type-2 cardiac ryanodine receptor (RyR2) that regulate cardiac contractile force through calcium release dynamics. His team examines RyR2 position/function in normal and diseased tissue using: Transmission electron microscopy Electron tomography 3D superresolution immunofluorescence Transgenic mouse models Ca 2+ spark/transient analyses Biochemical approaches Scientific Collaborations: The lab collaborates with Dr. Keng Chou (Chemistry Dept.) for dSTORM system development and is part of UBC's Cardiovascular Research Group . Current projects include: Investigating RyR2 variants' pathogenicity using iPSC-derived cardiomyocytes Studying dynamic RyR2 interactions through post-translational modifications Developing novel correlative microscopy techniques Lab Members: The interdisciplinary team includes Dr. Parisa Asghari (Research Associate), Dr. David Scriven (Research Associate), and Saif Dababneh (MD/PhD student).

Brian Kobilkaمشاهده پروفایل

استاد

• G protein-coupled receptors (GPCRs)
• Adrenergic receptor biology
• Receptor structure
• +۵ مورد دیگر

Brian Kobilka is a Professor of Molecular and Cellular Physiology at Stanford University School of Medicine, holding the Hélène Irwin Fagan Chair of Cardiology. He is a member of multiple prestigious institutes including Bio-X, the Cardiovascular Institute, the Maternal & Child Health Research Institute (MCHRI), and the Wu Tsai Neurosciences Institute. Dr. Kobilka's research focuses on G protein-coupled receptors (GPCRs), particularly adrenergic receptors. His laboratory studies receptor structure, intracellular trafficking, and the physiological relevance of receptor subtype diversity. Using techniques like cryo-EM, molecular dynamics, and single-molecule imaging, his team investigates conformational changes during receptor activation and G protein coupling. His recent publications reveal groundbreaking insights into GPCR mechanisms, including G protein coupling specificity, receptor activation pathways, and novel drug design approaches for pain management and metabolic disorders. His work bridges structural biology with therapeutic applications, with particular emphasis on understanding how receptor conformational changes translate to specific signaling outcomes. Nobel Prize in Chemistry (2012) for studies of G protein-coupled receptors American Academy of Arts and Sciences (2010) National Academy of Sciences (2009) Dr. Kobilka mentors numerous postdoctoral scholars, doctoral students, and medical scholars. His laboratory has trained many successful scientists who continue to advance the field of receptor pharmacology. His research is supported by multiple NIH grants and other funding sources that enable cutting-edge structural and biophysical investigations of receptor function. The Kobilka Lab at Stanford employs cutting-edge techniques including time-resolved cryo-EM, single-molecule fluorescence imaging, and molecular dynamics simulations to study GPCR structure and function. The lab maintains strong collaborations with pharmaceutical companies and academic researchers worldwide, focusing on translating basic science discoveries into therapeutic applications for cardiovascular disease, pain management, and neurological disorders.

Ronghua ZhuGeمشاهده پروفایل

استاد

• Calcium Signaling
• Ion Channel Biology
• Smooth Muscle Physiology
• +۳ مورد دیگر

Ronghua ZhuGe is a Professor at UMass Chan Medical School, affiliated with the T.H. Chan School of Medicine's Department of Microbiology. He holds additional positions at the NeuroNexus Institute and Morningside Graduate School of Biomedical Sciences. His research focuses on smooth muscle physiology, calcium signaling, and bitter taste receptor functions in extra-oral tissues. Dr. ZhuGe earned his B.S. from Zhejiang University and his Ph.D. from Iowa State University. His lab investigates mechanisms underlying smooth muscle contraction, including Ca²⁺ spark signaling, ion channel regulation, and the role of bitter taste receptors (TAS2Rs) in airway and uterine smooth muscle. Recent work explores TAS2R-mediated bronchodilation and tocolytic therapies for asthma and preterm labor. Techniques include patch-clamp electrophysiology, microscopy, and transgenic mouse models. Dr. ZhuGe teaches BBS 760: Introduction to Neuroscience, covering ion channels and neurotransmission. His lab actively recruits graduate students and postdoctoral fellows.

• Cardiovascular Medicine
• Hypertension
• Oxidative Stress
• +۳ مورد دیگر

Rheure Alves Moreira Lopes is an Honorary Research Fellow at the University of Glasgow's School of Cardiovascular & Metabolic Health. Their primary research focuses on vascular biology, hypertension, and oxidative stress mechanisms, with a particular interest in redox signaling pathways and their implications in vascular dysfunction. Key areas of investigation include the role of PARP/TRPM2, NADPH oxidases, and chemerin receptors in cardiovascular diseases such as hypertension, diabetes, and post-COVID-19 conditions. Lopes has contributed to over 35 peer-reviewed articles and book chapters, exploring topics ranging from hormonal influences on vascular reactivity to therapeutic targets for hypertension. Research interests prominently feature vascular dysfunction in hypertension, oxidative stress mechanisms in endothelial and smooth muscle cells, and the pathophysiological effects of hormones like testosterone. Their work bridges basic science with clinical applications, such as developing therapies targeting rho-kinase inhibition and evaluating ROS scavengers for genital skin healing in hypospadias. Lopes collaborates with international teams, including studies on aldosterone-induced vascular damage and the effects of high-fat diets on systemic oxidative stress. Publications highlight contributions to understanding VEGF inhibitor side effects, TRPM7 channel regulation, and the role of Nrf2 in protecting against vascular injury. Recent studies investigate salt-induced vascular damage and post-COVID-19 vascular mechanisms, underscoring translational relevance. Despite prolific output, no academic awards are explicitly mentioned in the text. Advising and grants involve collaborations on projects like testosterone's impact on vascular smooth muscle apoptosis and spironolactone's role in diabetic vascular protection. Their research often integrates molecular biology techniques with in vivo models, as demonstrated in methods chapters co-authored for hypertension protocols.

Coral Murrantمشاهده پروفایل

استاد

• Skeletal Muscle Physiology
• Microcirculation
• Intercellular Communication
• +۴ مورد دیگر

Coral Murrant is a Professor and Chair at the University of Guelph's Human Biology Department, specializing in skeletal muscle metabolism, fatigue, and blood flow regulation. Her research explores intercellular communication between muscle cells and vascular endothelial/smooth muscle cells, with collaborations in reproductive physiology (spiral artery function in pregnancy) and comparative physiology (fish microcirculation). Funded by NSERC, she is a member of the American Physiological Society and Microcirculatory Society. Education: B.Sc., University of Guelph Ph.D., University of Guelph Her work focuses on how skeletal muscle metabolic activity influences microvascular function, testing vasodilatory metabolites and their mechanisms. Collaborative projects include studying spiral artery dysfunction in pre-eclampsia and vascular adaptations in amphibious fish surviving out-of-water. She leads a large integrative physiology course for 440 students. Scientific Memberships: American Physiological Society Microcirculatory Society Her research has been supported by NSERC and collaborative NSERC/CIHR grants. Graduate students advised include Charter (PhD) and Hyde-Lay (MSc).

Christina M. Pabelickمشاهده پروفایل

استاد

• Airway Biology
• Pediatric Lung Diseases
• Asthma Mechanisms
• +۷ مورد دیگر

Christina M. Pabelick, M.D., is a Professor of Anesthesiology and Physiology at Mayo Clinic, with appointments in the Department of Anesthesiology and Perioperative Medicine, Physiology & Biomedical Engineering, and Pediatric and Adolescent Medicine. As Vice Chair of Research in Anesthesiology, she leads interdisciplinary teams studying airway diseases, particularly asthma in children, premature infants, and aging populations. Her work focuses on cellular mechanisms regulating airway structure/function using patient-derived samples and animal models to identify therapeutic targets for lung diseases. Education: MD, magna cum laude from Heinrich-Heine University (1988); residency in Anesthesiology at Mayo Clinic (2003); Fellowships in Cardiology and Anesthesia Research. Research Interests: Asthma mechanisms, oxygen toxicity, secondhand smoke effects, neonatal lung disease, mitochondrial dysfunction, and cellular senescence. Current projects include investigating hyperoxia-induced asthma in children and oxygen therapy impacts on premature infants, funded by NIH grants such as the Hydrogen Sulfide in Neonatal Airway Disease (2023–2025). Publications: Over 160 peer-reviewed articles in journals like American Journal of Physiology and British Journal of Pharmacology , emphasizing translational physiology and novel therapeutic strategies. Awards: FAER Research Starter Grant (2004), multiple research excellence awards, and leadership roles in Sigma Xi and the American Thoracic Society.

• Electrophysiology
• Smooth Muscle Physiology
• Urinary Tract Disorders
• +۵ مورد دیگر

Richard Lang is an Adjunct Senior Research Fellow in the Department of Physiology at Monash University, with a long-standing research focus on the electrophysiological and functional properties of pelvic smooth muscles, particularly the renal pelvis and prostate. His work investigates the role of interstitial cells in pacemaking and peristalsis, contributing significantly to understanding urinary tract physiology and disorders. His research interests lie at the intersection of electrophysiology , smooth muscle physiology , and urological function . He has extensively studied pacemaker mechanisms , calcium signaling , and interstitial cell networks in the renal pelvis and prostate, with implications for conditions like hydronephrosis, obstructive nephropathy, and benign prostatic hyperplasia. His work contributes to UN Sustainable Development Goals related to good health and well-being. The most recent articles highlight a strong trend in understanding spontaneous electrical activity , ion channel function , and pharmacological modulation in visceral smooth muscles, particularly through studies on Ca 2+ and Cl - currents, pericyte activity, and the effects of drugs like imatinib. His research combines electrophysiological , immunohistochemical , and functional approaches to unravel the mechanisms underlying peristalsis and tissue remodeling in health and disease. Role of calcium signals in interstitial cells in the male urogenital tract in health and disease (Australian Academy of Science) Remodeling of pacemaker mechanisms in ureteric peristalsis during obstruction (NHMRC) Control of uterine contraction: role of interstitial cells (NHMRC) Interstitial Cells of the Renal Pelvis: Signal Transduction in Nonobstructive Nephropathy (Japan Society for the Promotion of Science) Lang has contributed to academic training as Co-convenor of PHY4000 (BSc Hons) from 1994–2004, Co-convenor of BMS1052 in 2011, and Convenor of PHY2032 in 2012. While no formal students are listed, his collaborative projects suggest mentorship and supervision within research teams. He has no listed scientific awards in the provided text. His research has been conducted primarily within the Department of Physiology at Monash University, involving collaborations with researchers such as H. Hashitani, H. Parkington, and M. Kett. The work is centered on understanding fundamental physiological mechanisms in visceral smooth muscles, with potential translational applications in urology and nephrology.

Ollie Stewardمشاهده پروفایل

مربی

• Cell Biology
• Vascular Biology
• Ageing Research
• +۳ مورد دیگر

Ollie Steward is an Associate Tutor and PhD candidate at the University of East Anglia, Faculty of Science, School of Chemistry, Pharmacy and Pharmacology. He conducts research in the Warren cardiovascular lab group while supporting teaching activities across science programs. Education: Bachelor of Biomedical Science, University of East Anglia (2023) Masters by Research in Cardiovascular Science, University of East Anglia (recently completed) Doctor of Philosophy (PhD) candidate, University of East Anglia (current) Research Interests Steward investigates fundamental mechanisms of vascular ageing through dual focuses on cytoskeletal crosstalk in vascular smooth muscle cells (VSMCs) and matrix stiffness responses. His work integrates cellular ageing pathways with post-translational modification analysis, particularly examining how integrin alpha7beta1 deficiency alters satellite cell dynamics in skeletal muscle. This research bridges vascular biology, musculoskeletal physiology, and molecular signaling to address age-related degenerative processes. Scientific Awards No scientific awards, fellowships, or medals are documented in the available information. Advising and Grants As an early-career doctoral researcher, Steward has no formal advisees. The provided text contains no references to grants, funding sources, or research contracts associated with his projects. Laboratory Affiliations Steward is embedded in the Warren cardiovascular research group at UEA, where he utilizes advanced methodologies including primary vascular cell culture, polyacrylamide hydrogel systems for mechanical stimulation, confocal microscopy for cellular imaging, and western blotting for protein modification analysis. His technical expertise spans both vascular and musculoskeletal model systems.

• Smooth Muscle Physiology
• Gastrointestinal Motility
• Urinary Bladder Function
• +۷ مورد دیگر

Brian Perrino serves as an Associate Professor in the Department of Physiology and Cell Biology at the University of Nevada, Reno School of Medicine, where his research bridges molecular signaling and physiological function in gastrointestinal and urinary systems. Education: B.S. in Biology from Syracuse University Ph.D. from Boston University Post-Doctoral training at the Vollum Institute His research program centers on signaling pathways regulating cellular responses , with groundbreaking work on Mfge8-mediated regulation of stomach emptying . By inhibiting Rho kinase, Mfge8 increases myosin phosphatase activity and decreases gastric muscle contractions, optimizing nutrient absorption. This mechanism extends to diabetic gastroparesis and obesity-related gastric dysfunction , while parallel investigations explore PDGFRα+ cells in bladder pathophysiology and interstitial cells of Cajal in gut motility . Analysis of his 2020-2025 publications reveals consistent focus on smooth muscle contractility mechanisms across organ systems, with innovative approaches including spatial gene mapping, transcriptomic profiling, and functional assays in murine/non-human primate models. His work identifies critical pathways in bladder fibrosis, gastric emptying regulation, and neurogenic bladder dysfunction. Dr. Perrino has not listed any scientific awards in the provided materials. While specific advising details are unavailable, his extensive publication record suggests active mentorship in smooth muscle research. His work is institutionally supported through the Department of Physiology and Cell Biology, with potential external funding indicated by sustained research output. His laboratory integrates molecular characterization , functional physiology , and translational approaches to investigate smooth muscle signaling in gastrointestinal and urinary systems, maintaining strong emphasis on pathological conditions like diabetic complications and bladder inflammation.

Mary C. Beckerleمشاهده پروفایل

استاد

• Cell Biology
• Cancer Research
• Molecular Biology
• +۴ مورد دیگر

Mary C. Beckerle is a Professor of Biology and Adjunct Professor of Oncological Sciences at the University of Utah , where she has served since 1986. She is also the CEO and Director of the Huntsman Cancer Institute (HCI) and holds the Jon M. Huntsman Presidential Endowed Chair in Cancer Research . As a distinguished academic leader , she has directed graduate education initiatives, including the Interdepartmental Graduate Program in Molecular Biology and the Multidisciplinary Cancer Research Training Program at HCI. Education: B.A. from Wells College (1976) Ph.D. in Molecular, Cellular, and Developmental Biology from the University of Colorado at Boulder (1982) Beckerle is a noted cell biologist whose research has defined molecular pathways controlling cell movement and mechanotransduction, critical for cancer metastasis and embryonic development. Her work focuses on Ewing’s sarcoma , exploring how oncogenes disrupt cytoskeletal integrity and how novel therapies might target these mechanisms. Her recent articles (2018–2010) emphasize mechanisms of actin regulation , epigenetic drug targeting in sarcomas , and biomechanical signaling in cancer progression . These publications bridge fundamental cell biology with translational oncology, highlighting interdisciplinary approaches to tumor biology. Scientific Honors: Rosenblatt Prize for Excellence (2007) Alfred G. Knudson Award in Cancer Genetics (2018) Utah Governor’s Medal for Science and Technology (2001) Fellow of the National Academy of Sciences (2021) Member of the American Philosophical Society (2017) Beckerle’s mentoring legacy spans over 20 years, with her trainees now in prominent scientific roles. She has secured NIH and American Cancer Society grants for over three decades and led national initiatives like the Cancer Moonshot Blue Ribbon Panel . As CEO of HCI, she oversaw its designation as a Comprehensive Cancer Center and its recognition among U.S. News and World Report’s Best Cancer Hospitals . Her Beckerle Lab investigates zyxin and LIM proteins in actin stress fiber dynamics and tumor progression. She also collaborates with international institutions, including the Mechanobiology Institute in Singapore and the National Centre for Biological Sciences in India .