جست‌وجوی استاد و پژوهشگر

Barbara Stefanskaمشاهده پروفایل

دانشیار

• Epigenetics
• Cancer Epigenetics
• Nutritional Epigenomics
• +۲ مورد دیگر

Barbara Stefanska is an Associate Professor at the University of British Columbia, affiliated with the Faculty of Land and Food Systems and the Department of Food, Nutrition & Health. Her research focuses on nutriepigenomics, exploring how dietary bioactive compounds like polyphenols modulate epigenetic mechanisms in cancer prevention and therapy. She also serves on the editorial board of the British Journal of Pharmacology and leads the Stefanska Lab, which investigates epigenetic enzymes and chromatin-modifying proteins. Education: PhD in Biomedical Sciences (Nutritional Epigenomics) from Medical University of Lodz (2003–2007), Post-Doc in Cancer Epigenetics at McGill University (2008–2013) Her research examines the role of phytoestrogens in reversing DNA methylation patterns linked to cancer progression, with a particular emphasis on DNMTs , TETs , and chromatin interactions . Recent studies highlight their effects on aging-related genes and mitochondrial apoptosis in gastrointestinal cancers. Recent publications demonstrate a focus on epigenetic therapy , gene expression modulation, and nutritional interventions for diseases like hepatocellular carcinoma and breast cancer. Fellowship of the British Pharmacological Society (2024) Editor’s Performance Award, British Journal of Pharmacology (2018) Multiple Erasmus Plus Scholar awards (2018–2023) Dr. Stefanska supervises graduate students in Human Nutrition and co-authored over 15 high-impact publications between 2015–2025. Her lab employs cutting-edge genomic technologies and collaborates with institutions like Imperial College London and University of Missouri.

Igor Golicمشاهده پروفایل

پژوهشگر

• Cell Biology
• Molecular Biology
• Reproductive Biology
• +۳ مورد دیگر

Igor Golic serves as a Senior Research Associate at the Faculty of Biology, University of Belgrade, specializing in Cell Biology. His research is centered at the intersection of cellular metabolism, oxidative stress responses, and tissue remodeling across multiple physiological systems. Based at Studentski trg 3, 11000 Belgrade, he maintains active research operations with direct contact via igor.golic@bio.bg.ac.rs and +381 11 2635 627. His primary research domains include: Adipose tissue biology and metabolic remodeling Mitochondrial dynamics in brown/white adipocytes Oxidative stress mechanisms in reproductive tissues Thyroid hormone regulation of cellular metabolism Nanoparticle-cellular interactions Sperm quality and chromatin architecture These interests manifest in investigations of hypothyroidism, obesity, cancer microenvironments, and infertility through advanced cellular and molecular techniques. Analysis of his 2021-2025 publications reveals consistent focus on redox signaling pathways and mitochondrial adaptations in metabolic disorders. His work demonstrates methodological diversity including immunohistochemistry, electron microscopy, fractal analysis, and single-cell spectroscopy, particularly examining adipose tissue remodeling in response to cold exposure, dietary challenges, and endocrine disruptions. Recurring themes include Nrf2 signaling, zinc transporter dynamics, and peroxisomal heterogeneity. No scientific awards were documented in available sources. Information regarding student supervision, grant funding, or collaborative projects remains unspecified in current materials, though his publication record indicates collaboration with researchers including Rakic Mina and Djordjevic Vladan. Laboratory affiliations and team structures are not detailed in the provided texts.

Frank Huynhمشاهده پروفایل

استادیار

• Physiology
• Biochemistry
• Endocrinology
• +۳ مورد دیگر

Frank Huynh is an Assistant Professor in the Department of Cellular & Physiological Sciences at the University of British Columbia's Faculty of Medicine. His research focuses on the metabolic regulation of aging and endocrine physiology, particularly the roles of sirtuins in glucose, lipid, and amino acid metabolism. PhD in Physiology, University of British Columbia BSc in Biochemistry, University of British Columbia Postdoctoral training at Duke University Medical Center Dr. Huynh has a long-standing interest in integrative physiology, with specific expertise in: Endocrine regulation of metabolism Metabolic aging mechanisms Sirtuin family enzymes Diabetes and insulin resistance His peer-reviewed publications (2017–2020) reveal a consistent focus on: Sirtuin-mediated metabolic control Mitochondrial and peroxisomal dynamics Nutrient-sensing pathways Aging-related metabolic dysfunction As an educator, Dr. Huynh has taught undergraduate physiology labs and graduate integrative physiology courses across multiple institutions.

Jeanne Stuckeyمشاهده پروفایل

استاد پژوهشی

• Targeted Protein Degradation
• Medicinal Chemistry
• Cancer Biology
• +۳ مورد دیگر

Jeanne Stuckey is a Research Professor at the Life Sciences Institute of the University of Michigan , specializing in Medicinal Chemistry and Cancer Biology . Her work focuses on the development of targeted protein degradation therapies and small-molecule inhibitors for oncological applications. Research Areas: Targeted Protein Degradation (STAT3/5/6, SMARCA2/4), RNA Splicing, Eukaryotic Translation, Mitochondrial Metabolism Key Collaborators: Shaomeng Wang, Jennifer Meagher, Chao-Yie Yang, Duxin Sun Her publications demonstrate expertise in designing PROTAC degraders and prodrugs for cancer-related targets, including SMARCA2 (synthetic lethality in SMARCA4-deficient cancers), STAT3/5/6 (oncogenic transcription factors), and eIF4E (cap-dependent translation). She has contributed to advancements in BRD4 inhibitors and ST2 inhibitors for antitumor and anti-inflammatory applications. Recent work includes the development of SMD-3236 (SMARCA2 degrader), SD-436 (STAT3 degrader), and AK-1690 (STAT6 degrader), highlighting her focus on precision oncology and molecular targeting. She also co-authored studies on SIRT5 variants and PKM2 activators for metabolic and neuroprotective applications.

• Cardiovascular Diseases
• Oxidative Stress
• Autophagy
• +۵ مورد دیگر

Valentina Valenti is a Researcher at the Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome . Her work spans cardiovascular diseases, oxidative stress, autophagy, and molecular mechanisms in cardiac remodeling. Specializes in coronary artery disease, heart failure, and environmental influences on cardiovascular health Active in translational research using animal models and clinical cohorts Research Trends Her recent publications focus on: Mitophagy modulation for cardioprotection Autophagy activators (e.g., trehalose) in myocardial infarction Environmental factors (pollution, climate change) influencing cardiovascular events Comparative toxicity of tobacco products using the SUR-VAPES study framework Epigenetic mechanisms in vascular oxidative stress Prognostic imaging tools for coronary artery disease Publications Key themes include coronary artery calcium scoring, vascular dysfunction, and genetic variants affecting thrombosis. Recent work (2025) examines carotid web-related strokes in young patients.

Marija Pinterićمشاهده پروفایل

مدرس ارشد

• Molecular Biology
• Biochemistry
• Cell Biology
• +۷ مورد دیگر

Marija Pinterić is a Senior Lecturer at the Ruđer Bošković Institute, affiliated with the Laboratory for Metabolism and Aging under the Division of Molecular Medicine. Her research focuses on molecular biology, biochemistry, and cell biology, particularly the role of Sirtuin 3 (SIRT3) in aging, oxidative stress, cancer progression, and plant metabolic responses to environmental stimuli. Education: She earned her Master’s degree in Molecular Biology from the University of Zagreb in 2014, with a thesis analyzing SSB protein genes in Phytoplasma genomes. Her research spans two major domains: (1) Molecular Mechanisms in Aging and Cancer , including SIRT3-mediated regulation of mitochondrial function, sex-specific responses to oxidative stress, and interactions with estrogen signaling pathways in breast cancer cells; and (2) Plant Biochemistry , investigating phytochemical adaptations in broccoli and Chinese cabbage under temperature stress, linking metabolite profiling to nutritional and bioactive properties. Recent publications highlight her work on SIRT3’s tumor-suppressive effects under hyperoxia, sex-based metabolic differences in aging, and plant-based antioxidant discovery. She collaborates on interdisciplinary studies involving LC-DAD-MS phytochemical analysis and molecular oncology. Her laboratory contributions at Ruđer Bošković Institute emphasize metabolic and redox signaling in aging and cancer, with a focus on translational applications of mitochondrial regulators and plant-derived bioactives.

• Molecular Medicine
• Biomedical Sciences
• Oxidative Stress
• +۱۲ مورد دیگر

Marijana Popović Hadžija is a Senior Research Associate at the Ruđer Bošković Institute in Zagreb, Croatia, specifically affiliated with the Laboratory for Metabolism and Aging under the Division of Molecular Medicine . Her work bridges biomedical sciences with molecular mechanisms in aging, diabetes, and cancer, focusing on mitochondrial function and oxidative stress. University: Ruđer Bošković Institute Department: Laboratory for Metabolism and Aging Academic Rank: Researcher Research Interests Molecular Medicine Oxidative Stress and Mitochondrial Dynamics Sex-Specific Biology in Aging and Cancer Diabetic Embryopathy and Neural Tube Defects Gene Expression Profiling in Metabolic Disorders Hormonal Regulation of Antioxidant Pathways Recent Article Trends emphasize Sirtuin 3 (SIRT3) as a critical regulator of sex-specific responses to aging and oxidative stress, with implications in breast cancer and metabolic diseases. Her work explores how SIRT3 modulates mitochondrial fitness, redox signaling, and estrogen-dependent pathways, often in collaboration with multidisciplinary teams. Advising includes mentoring graduate and postgraduate students on topics like TNF-α polymorphisms in diabetes, SIRT3's role in cancer, and hyperoxia-induced oxidative stress. Notable advisees include Perković Adrijana , Jemin Nikolina , and Vukadinović Gabrijela . Labs & Collaborations involve the Laboratory for Metabolism and Aging , with partnerships in cancer biology, metabolic disorders, and biomedical imaging.

Sandra Sobočanecمشاهده پروفایل

استادیار

• Molecular Medicine
• Metabolism and Aging
• Sirtuin 3 Research
• +۵ مورد دیگر

Sandra Sobočanec is an Assistant Professor and Senior Research Associate at the Ruđer Bošković Institute's Division of Molecular Medicine, Laboratory for Metabolism and Aging in Zagreb, Croatia. Her research focuses on molecular mechanisms of aging, metabolism, and oxidative stress with particular emphasis on sex-specific responses. Her primary research interests include Sirtuin 3 (SIRT3) biology , sex-dimorphic metabolic responses , mitochondrial function , and oxidative stress in aging and disease . Current work investigates SIRT3's role in obesity-related diseases through the HrZZ IP-2020-10-4806 project "Obese Sirt". Her studies reveal fundamental sex differences in metabolic regulation, particularly in hepatic and neuronal systems under high-fat diet conditions and oxidative stress. Analysis of her 15 most recent publications shows a consistent focus on SIRT3-mediated redox signaling across multiple model systems including mouse embryonic fibroblasts, breast cancer cells (MCF-7, MDA-MB-231), and in vivo murine models. Key trends include sex-specific gene expression patterns, interactions with estrogen signaling, and therapeutic potential of SIRT3 modulation in metabolic disorders and cancer. Dr. Sobočanec has supervised graduate research including Grazia Davidović's diploma thesis on SIRT3's tumor-suppressive effects. She collaborates extensively within the Ruđer Bošković Institute and with international partners on projects involving hyperoxia therapy, mitochondrial metabolism, and cancer biology.

Ji-Young Leeمشاهده پروفایل

استاد

• Non-alcoholic fatty liver disease
• Alcoholic hepatitis
• Immunometabolism
• +۷ مورد دیگر

Ji-Young Lee is a Professor and Department Head at the University of Connecticut in the Department of Nutritional Sciences. She is affiliated with the Genomic and Mechanistic Metabolism Group (GMMG) and the Immuno-Cardio Group (ICG), and leads the NP-OILD Lab. Ph.D. in Nutrition, University of Nebraska-Lincoln M.S. in Nutritional Science and Dietetics, University of Nebraska-Lincoln M.S. in Food Chemistry, Kyung Hee University B.S. in Foods and Nutrition, Kyung Hee University Dr. Lee's research focuses on the molecular mechanisms linking energy metabolism, chronic inflammation, and dyslipidemia to obesity-related diseases like non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and cardiovascular disease. She investigates dietary interventions (e.g., blue-green algae, berries, astaxanthin) that modulate histone deacetylases (HDAC4 and HDAC9) to mitigate disease progression. Her recent publications highlight the role of bioactive compounds (fucoxanthin, astaxanthin, spirulina) in reducing liver inflammation, fibrosis, and oxidative stress via pathways like Nrf2 activation, NF-kB inhibition, and Sirtuin 1 regulation. Key trends include the efficacy of marine-derived antioxidants, gender-specific responses to HDAC4 depletion, and the impact of dietary polyphenols on metabolic syndrome. Dr. Lee is actively involved in collaborative research through the Institute for Systems Genomics at UConn and The Jackson Laboratory. Her work bridges nutritional biochemistry, immunometabolism, and epigenetic regulation to address chronic diseases.

Richard Wilsonمشاهده پروفایل

استاد

• Plant Pathology
• Molecular Plant-Microbe Interactions
• Fungal Genetics
• +۴ مورد دیگر

Richard Wilson holds the Charles Bessey Professorship in the Department of Plant Pathology at the University of Nebraska-Lincoln's College of Agricultural Sciences and Natural Resources (IANR). His position represents an endowed chair recognizing significant contributions to plant pathology and molecular plant-microbe interactions. Dr. Wilson's research program investigates molecular mechanisms of fungal pathogenesis, with primary focus on the rice blast fungus Magnaporthe oryzae. He examines effector secretion pathways, host immunity suppression strategies, metabolic adaptation during plant infection, and nutrient acquisition mechanisms. His work increasingly integrates synthetic biology approaches for developing engineered living materials, including self-healing concrete systems and Martian construction applications using microbial consortia of cyanobacteria and fungi. Analysis of his publication trajectory reveals a progression from fundamental studies of cereal crop disease mechanisms toward interdisciplinary applications in sustainable materials science. Recent work demonstrates innovative convergence of plant pathology with astrobiology and construction engineering, particularly through co-culturing systems for extraterrestrial habitat development while maintaining core investigations into fungal virulence. Dr. Wilson has been honored with the Charles Bessey Professorship, a distinguished endowed chair at the University of Nebraska-Lincoln. Charles Bessey Professorship Details regarding Dr. Wilson's graduate student mentorship, specific research grants, and laboratory infrastructure were not provided in the available text. His research is conducted within the Department of Plant Pathology, leveraging collaborative networks across plant sciences, microbiology, and engineering disciplines to address challenges in plant disease resistance and sustainable material innovation.

Katharine Diehlمشاهده پروفایل

استادیار

• Chromatin
• Histone Modifications
• Epigenetics
• +۳ مورد دیگر

Katharine Diehl is an Assistant Professor of Medicinal Chemistry at the University of Utah, affiliated with the Biological Chemistry Program and Molecular Biology Program. Education B.S. University of North Carolina at Chapel Hill Ph.D. University of Texas at Austin Research Focus Her laboratory investigates epigenetic mechanisms linking cellular metabolism to genomic regulation via chromatin dynamics. Key areas include: Development of metabolite biosensors for live-cell tracking (e.g., acetyl-CoA). Role of non-canonical histone acyl PTMs (e.g., lactylation) and their regulation by enzymes like sirtuins. SIRT6-mediated mono-ADP-ribosylation of polyhistidine proteins in nuclear regulation. Methodology : Integrates organic chemistry, protein engineering, biochemistry, and molecular biology. Publications : Recent work (2017–2025) explores chromatin-metabolism crosstalk, histone modifications, enzyme mechanisms (SIRT6/PRC2), and metabolite imaging. Dominant themes include epigenetics, metabolic signaling, and chromatin biochemistry. Lab : Leads an active research group; details available on her lab page .

Fajun Yangمشاهده پروفایل

استاد

• Regulation of Gene Transcription
• Lipid Metabolism
• Glucose Metabolism
• +۷ مورد دیگر

Fajun Yang is a Professor at Albert Einstein College of Medicine, holding dual appointments in the Department of Medicine (Endocrinology) and the Department of Developmental & Molecular Biology. Their research focuses on the transcriptional regulation of lipid and glucose metabolism, particularly in hepatocytes and adipocytes, with an emphasis on the Mediator complex's role in SREBP signaling. Education details are not explicitly stated in the provided text. Yang's work investigates metabolic diseases such as type 2 diabetes, obesity, and fatty liver disease through biochemical and genetic approaches. Key research interests include the molecular mechanisms controlling lipid homeostasis, transcriptional cofactors like the Mediator complex, and the interplay between metabolic signals and gene expression. Their studies aim to identify therapeutic targets for metabolic syndrome. No specific advising or grant information was provided. Yang's lab is actively engaged in understanding the Mediator complex's dynamic regulation of metabolic pathways and exploring compounds that modulate lipid metabolism.

Thierry Arnouldمشاهده پروفایل

استاد

• Cell Biology
• Mitochondrial Biology
• Cellular Stress Responses
• +۵ مورد دیگر

Thierry Arnould is a Professor at the University of Namur, affiliated with the Namur Research Institute for Life Sciences and the Laboratory of Cellular Biochemistry and Biology. He holds a Doctor of Science from the University of Namur (1994). His research focuses on mitochondrial biology, cellular stress responses, and metabolic diseases. Key areas include understanding mitochondrial function in stem cell differentiation, cancer cell metabolism, and host-pathogen interactions. Education: Doctor of Science (1994): University of Namur – Thesis on hypoxia-reoxygenation effects on endothelial cells Master in Biology (1989): University of Namur – Thesis on hypoxia mechanisms in endothelial cells Research Interests: Dr. Arnould explores mitochondrial dynamics, cellular responses to stress (e.g., lipotoxicity, hypoxia), and translational applications in regenerative medicine. His work bridges basic science and clinical applications, including therapies for diabetes, osteoarthritis, and infectious diseases caused by pathogens like Brucella abortus. Projects & Grants: Active projects include developing natural treatments for non-alcoholic fatty liver disease, studying mitochondrial roles in liver dysfunction, and investigating stem cell therapies for cartilage repair. He has led over 55 projects since 1999, with funding for studies on lipid metabolism, mitochondrial protein import, and proton therapy enhancement via mitophagy. Labs & Teams: His laboratory collaborates internationally on mitochondrial biology and hosts interdisciplinary teams investigating cellular biochemistry, proteomics, and disease modeling. He actively supervises PhD students and organizes academic events like the 'PhD Student Day UNamur-UCLouvain.'

Qiang Tongمشاهده پروفایل

دانشیار

• Molecular Biology
• Metabolism
• Obesity Research
• +۳ مورد دیگر

Qiang Tong, Ph.D., is an Associate Professor at Baylor College of Medicine with primary affiliation in the Pediatrics-Nutrition Department. He holds additional roles in Medicine, Molecular Physiology & Biophysics, and is a member of the Dan L Duncan Comprehensive Cancer Center and Children's Nutrition Research Center. His research focuses on molecular mechanisms of caloric restriction, adipose tissue development, and metabolic disorders linked to obesity, diabetes, and cancer. Education: PhD from Ohio State University (1997) BS from University of Science and Technology of China (1987) MS from Shanghai Institute of Cell Biology (1990) Postdoctoral Fellowship at Harvard School of Public Health (2002) Research Interests: Mechanisms of caloric restriction's lifespan extension and disease prevention Role of sirtuins (SIRT2, SIRT3) in oxidative stress, adipogenesis, and metabolic regulation Adipocyte-derived factors in insulin resistance and type-2 diabetes PU.1 transcription factor's role in obesity-associated inflammation Recent Work Trends: Focus on SIRT3's role in autophagy, mitochondrial function, and liver regeneration Investigation of adipose tissue plasticity and its impact on systemic metabolism Exploration of therapeutic targets for obesity-related metabolic diseases Labs/Teams: Leads a lab studying sirtuin signaling and metabolic pathways Affiliated with the Children's Nutrition Research Center Collaborates on projects linking adipose biology to cancer pathogenesis

Weiwei Dangمشاهده پروفایل

دانشیار

• Epigenetics
• Aging Research
• Cancer Biology
• +۳ مورد دیگر

Weiwei Dang is an Associate Professor at Baylor College of Medicine, affiliated with the Huffington Center On Aging and the Department of Molecular and Human Genetics. He also serves as a Member of the Dan L Duncan Comprehensive Cancer Center and a Basic Science Representative in the Faculty Senate. His research focuses on epigenetic mechanisms regulating aging and age-related cancers, using yeast replicative aging models and mammalian stem cells. Key areas include histone modifications, chromatin architecture, and stress response pathways. Education: PhD from Southern Illinois University (2006), Post-Doctoral Fellowship at the University of Pennsylvania (2011). His lab has received grants from the National Institute on Aging (NIA) for projects such as 'Regulation of longevity through maintenance of transcription fidelity' (R01AG052507) and 'Molecular mechanisms of cellular response to age-associated chromatin changes' (R01AG081347). Research highlights include discoveries of cryptic transcription in aging cells and the CAD response mechanism, which promotes longevity by addressing chromatin defects. Collaborative efforts with postdocs (e.g., Brenna McCauley, Qinghao Zhang) and graduate students (e.g., Nic Nikoloutsos) advance understanding of epigenetic pathways in aging and oncogenesis.