جست‌وجوی استاد و پژوهشگر

Philip Willkeمشاهده پروفایل

استاد

• Quantum Physics
• Nanomagnetism
• Scanning Probe Microscopy
• +۴ مورد دیگر

Philip Willke is a Tenure-Track Professor leading the Quantum Systems on Surfaces research group at the Institute of Physics, Karlsruhe Institute of Technology (KIT). His laboratory focuses on atomic-scale quantum engineering using scanning tunneling microscopy combined with electron spin resonance techniques. His research centers on quantum coherent control of atomic-scale spin systems, with emphasis on imaging and manipulating individual atoms and molecules to develop new quantum sensors and information processing architectures. Key methodologies include single-atom magnetic resonance imaging, nuclear spin detection, and spin engineering of molecular systems on surfaces. His work bridges fundamental quantum physics with applications in quantum computing and nanoscale sensing. Recent publications reveal strong trends in quantum spin engineering of molecular ferrimagnets (2025), coherent spin dynamics in single atoms (2024), and breakthroughs in atomic-scale magnetic field control. The research spans quantum physics, nanotechnology, and condensed matter systems, with consistent focus on atomic-scale precision and quantum coherence preservation. Emmy-Noether Research Grant (2020) ERC Starting Grant ATOMQUANT (2024) Willke actively supervises PhD and Master's students including Paul Greule, Wantong Huang, Adrian Seiler, and Arian Vosoghi Marand. His group develops cutting-edge instrumentation including dilution refrigerator scanning tunneling microscopes. Current projects funded by major grants focus on coherent manipulation of atomic/nuclear spins, quantum sensor development, and molecular spin systems for quantum information applications. The WillkeLab, founded in 2020 at KIT's Physics Institute, operates state-of-the-art scanning probe instrumentation including quantum-coherent STM systems. The team collaborates with Wolfgang Wernsdorfer (KIT), Sebastian Loth (University of Stuttgart), and Mario Ruben (KIT) while maintaining ties with IBM and the Center for Quantum Nanoscience.

Joachim Frankمشاهده پروفایل

استاد

• Cryo-Electron Microscopy
• Structural Biology
• Molecular Machines
• +۳ مورد دیگر

Joachim Frank is a Professor at Columbia University in the Departments of Biochemistry and Molecular Biophysics and Biological Sciences. He pioneered single-particle cryo-electron microscopy (cryo-EM), enabling 3D structural analysis of biomolecules. His work revolutionized structural biology, particularly in studying ribosomes, hemocyanins, and membrane proteins. Frank joined Columbia in 2008 after a 33-year tenure at the Wadsworth Center, NY State Department of Health. Education: PhD in Physics from Technical University Munich (1970), Postdoctoral fellowships at JPL (Caltech), Berkeley, and Cornell. Key mentors included Walter Hoppe (Munich) and Richard Henderson (Cambridge). Research Interests: Development of cryo-EM techniques, single-particle averaging, 3D reconstruction algorithms, and applications to molecular machines like the ribosome. His lab created SPIDER, a seminal image processing software system. Awards: Nobel Prize in Chemistry (2017), HHMI Investigator (1998–2017), Harkness Fellowship (1970), and Humboldt Fellowship (1994). Nobel Prize for developing cryo-EM to image biomolecules in atomic detail. HHMI funding supported groundbreaking projects on ribosome function and structural biology. Advising & Grants: Advised over 20 students/postdocs including Rajendra Agrawal (ribosome biochemist) and Christian Spahn (structural biologist). NIH grants sustained decades of cryo-EM research. HHMI provided critical funding for advanced microscopy infrastructure at Columbia. Labs & Collaborations: Frank Lab at Columbia focuses on cryo-EM applications. Notable collaborations with Jean Lamy (hemocyanin studies), Måns Ehrenberg (ribosome dynamics), and Ruben Gonzalez (single-molecule FRET).

Alexandra Schambonyمشاهده پروفایل

استاد پژوهشی

• Biophysics
• Single-Molecule Imaging
• Protein Dynamics
• +۶ مورد دیگر

Alexandra Schambony is a Senior Scientist in the Department of Sandoghdar at the Max Planck Institute for the Science of Light (MPL), Erlangen, Germany. Her research focuses on understanding protein diffusion and transport in living cells using advanced optical techniques. Research Interests: Dr. Schambony specializes in single-molecule biophysics, particularly the dynamics of transmembrane proteins. She employs interferometric scattering (iSCAT) microscopy and cryogenic light microscopy to study protein behavior in native cellular environments with ultra-high precision. The available publication demonstrates a strong focus on structural and functional analysis of the PIEZO1 ion channel, using innovative spCryo-LM to resolve conformational states at Ångstrom-level accuracy. This work bridges biophysics, structural biology, and advanced imaging. Scientific Contributions: Developed and applied cryogenic light microscopy for in situ protein conformation studies Advanced understanding of PIEZO1 structural dynamics in native membranes Advising and Grants: While no formal students or grants are listed, her senior scientist role and publication record suggest active mentorship and involvement in competitive research funding, likely through Max Planck Society and collaborative grants. Labs and Teams: She is a key member of the Sandoghdar Department at MPL, which pioneers label-free optical microscopy and single-molecule detection techniques. The team focuses on developing and applying novel biophysical tools to address fundamental questions in cell biology.

Madeline Memovichمشاهده پروفایل

پژوهشگر

• Free-Electron Laser Science
• Structural Biology
• Macromolecular Imaging
• +۴ مورد دیگر

Madeline Memovich is a Postdoctoral researcher at the Center for Free-Electron Laser Science (CFEL) within Deutsches Elektronen-Synchrotron (DESY) in Hamburg, Germany, focusing on advanced imaging techniques using X-ray free-electron lasers. Her work bridges physics, structural biology, and computational science to solve macromolecular structures. Her research spans Free-Electron Laser Science, Structural Biology, and Macromolecular Imaging, with emphasis on laser-induced molecular alignment for single-particle diffractive imaging (SPI). Key interests include overcoming orientation challenges in SPI, improving resolution for protein structure determination, and integrating machine learning with quantum dynamics simulations. Recent breakthroughs involve geometric confinement of molecules to enhance image reconstruction fidelity. Dr. Memovich's 2025 publications reveal interdisciplinary trends: merging nanotechnology with laser physics for quantum dot analysis, optimizing computational fluid dynamics for nanoparticle injection, and applying normalizing flows to quantum chemistry. This reflects her dual focus on experimental methodology development and computational innovation for macromolecular imaging. She operates within CFEL's collaborative framework involving DESY, Max Planck Society, and University of Hamburg, utilizing facilities like the European XFEL. Her team recently demonstrated laser-alignment techniques that significantly advance SPI capabilities for structural biology applications.

Thomas Genschمشاهده پروفایل

پژوهشگر

• Fluorescence Microscopy
• Spectroscopy
• Biophysics
• +۴ مورد دیگر

Dr. Thomas Gensch is a Researcher and group leader at the Institute for Biological Information Processes (IBI) , specifically in the Molecular and Cellular Physiology (IBI-1) department at Research Center Jülich . He joined in 2000, leading the fluorescence microscopy and spectroscopy group, and has supervised approximately 30 students (bachelor, master, diploma, PhD), including one current PhD candidate. He holds a Diploma in Physics from Humboldt University Berlin (1992) and a PhD in Biophysics from Heinrich-Heine-University Düsseldorf/Max-Planck-Institute of Radiation Chemistry (1996, summa cum laude ). His research focuses on advanced fluorescence techniques (e.g., lifetime imaging, FRET, single-molecule microscopy) applied to cellular physiology, with expertise in genetically encoded sensors and fluorescent proteins. Recent work explores singlet oxygen generation, phototoxicity, and applications in nanomedicine and optogenetics. His publications emphasize optical biosensors, super-resolution microscopy, and protein engineering. Awards include the Casimir-Ziegler Award (1997) and a Marie-Curie Postdoc Grant (1998–1999).

Christian Eggelingمشاهده پروفایل

استاد

• Biophysics
• Imaging Technology
• Cell Biology
• +۶ مورد دیگر

Prof. Dr. Christian Eggeling is the Head of the Biophysical Imaging Research Department at the Leibniz Institute of Photonic Technology (Leibniz-IPHT). His work bridges advanced optical techniques with cellular biophysics, focusing on nanoscale imaging and molecular dynamics in biological systems. Institution: Leibniz Institute of Photonic Technology (Leibniz-IPHT) Role: Professor and Department Head Research interests include: Super-resolution microscopy (STED, dSTORM) Single-molecule tracking and fluorescence correlation spectroscopy (FCS) Biophysical characterization of cellular structures (lipids, proteins, extracellular vesicles) Development of novel imaging technologies (iSCAT-TIRF, PiF-IR) Recent publications highlight his group's innovations in: Overcoming photoconversion artifacts in confocal/STED microscopy Combining organ-on-chip models with imaging to study gut-lung axis interactions Quantifying candidalysin neutralization as a therapeutic strategy for vulvovaginal candidiasis Advancing iSCAT and PiF-IR for nanoparticle tracking and protein structure analysis Optimizing membrane vesicle production methods for biomedical applications Technical focus spans optical engineering, computational data processing (e.g., neural networks for artifact correction), and interdisciplinary applications in virology, immunology, and cellular biophysics.

• Biophysical Imaging
• Membrane Biophysics
• Biomolecular Condensates
• +۴ مورد دیگر

Ziliang Zhao is a Research Scientist in the Biophysical Imaging Department at the Leibniz Institute of Photonic Technology (Leibniz-IPHT) in Jena, Germany. His work focuses on the intersection of advanced imaging techniques and fundamental biophysical processes, particularly examining how biomolecular condensates interact with cellular membranes. Dr. Zhao's research interests span multiple domains of biophysics and membrane science. His work primarily investigates the complex interactions between biomolecular condensates and lipid membranes, exploring how these interactions lead to remarkable morphological transformations including membrane wetting, fingering phenomena, and the formation of double-membrane sheets. He employs cutting-edge microscopy techniques, especially STED (stimulated emission depletion) super-resolution microscopy, to visualize and analyze highly curved membrane structures that are beyond the diffraction limit of conventional light microscopy. His research bridges fundamental biophysical principles with potential applications in synthetic cell engineering and understanding cellular organization. Analysis of Dr. Zhao's publication record from 2021-2025 reveals a consistent research trajectory focused on membrane biophysics and biomolecular condensates. His work demonstrates increasing sophistication in both experimental approaches and theoretical understanding. A notable trend is his progression from studying basic membrane properties to examining complex interactions between membranes and biomolecular condensates, with applications in synthetic biology. His publications appear in high-impact journals including Nature Communications, PNAS, and Advanced Materials, indicating significant contributions to the field. Dr. Zhao maintains an active research program with multiple ongoing collaborations, particularly with researchers such as Dimova, Lipowsky, and Eggeling. His work demonstrates both experimental and theoretical approaches to understanding membrane biophysics, with practical applications in developing more realistic synthetic cell models. The research group appears to be well-equipped with advanced microscopy facilities, particularly for super-resolution imaging of dynamic membrane processes.

Julia Preobraschenskiمشاهده پروفایل

پژوهشگر

• Membrane Dynamics
• Neurotransmission
• Hearing Research
• +۳ مورد دیگر

Dr. Julia Preobraschenski serves as a Researcher leading the Preobraschenski Group at the Institute for Auditory Neuroscience (IAN), University of Göttingen. Her laboratory investigates fundamental mechanisms of membrane dynamics with emphasis on ferlin proteins critical for auditory and muscular function. Her primary research focuses on otoferlin in auditory synapses and dysferlin in muscle membrane repair. Utilizing a bottom-up reconstitution approach with purified proteins in artificial membranes, her group employs biochemical assays, biophysical measurements, and structural techniques including cryo-electron microscopy and X-ray crystallography. Key objectives include elucidating calcium-dependent membrane fusion mechanisms, vesicle priming dynamics, and phospholipid interactions in neurotransmission and cellular repair processes. Analysis of her 2019-2022 publications reveals consistent contributions to membrane biophysics and synaptic function, with recurring themes in V-ATPase regulation, neurotransmitter transporter dynamics, and vesicle subpopulation heterogeneity. Her work frequently employs single-molecule methodologies and advanced imaging to dissect molecular mechanisms underlying hearing disorders and muscular pathologies. Dr. Preobraschenski's laboratory includes current members such as Dr. Abhishek Acharya, with former contributors including Huong Giang Doan, Irene Gomez Garrote, Mayan-Olivia Langer, and Mehar Monga. The group operates within IAN's collaborative framework alongside specialized teams including the Cretu, Goßler, and Moser groups, all focused on auditory neuroscience and translational hearing research.

Stephan Nussbergerمشاهده پروفایل

استاد

• Biophysics
• Biochemistry
• Protein Translocation
• +۶ مورد دیگر

Prof. Dr. Stephan Nussberger is a full Professor of Biophysics and Head of the Department of Biophysics at the University of Stuttgart’s Institute of Biomaterials and Biomolecular Systems. He holds a PhD in Physics from the Technical University of Munich (1993), with postdoctoral training at Harvard University (1994–1995) and Ludwig-Maximilians-University Munich (1996–2003). His research focuses on mitochondrial protein translocation mechanisms, apoptosis regulation via BAX palmitoylation, and nanopore-based biosensing technologies. He teaches Biophysics, Bioanalytics, and Biomechanics of the Cell to undergraduate and graduate students in Technical Biology, Biomedical Engineering, and Sports programs. Key roles: Chair of Biophysics (since 2003), Head of Stuttgart Research Center for Systems Biology Research interests: Mitochondrial membrane translocase (TOM complex), synthetic biology applications, single-molecule microscopy, and cancer cell apoptosis mechanisms He has led major initiatives such as the BMBF-funded Clusters4Future Nanodiag BW and the Baden-Württemberg Foundation’s Functional Nanostructures program. Over 200 publications span structural biology, biochemistry, and biophysics, with notable work in Nature Materials , Science Advances , and PNAS . Awards include DFG and EMBL fellowships.

Ulrike Endesfelderمشاهده پروفایل

استاد

• Cellular Biophysics
• Microbiology
• Single-Molecule Localization Microscopy
• +۳ مورد دیگر

Prof. Ulrike Endesfelder is a Professor in the Institute for Microbiology and Biotechnology at the University of Bonn. Her research focuses on microbial cell biology, combining quantitative single-molecule microscopy and biophysical methods to study molecular processes in microorganisms. She leads the Endesfelder Research Group , which develops novel microscopy techniques and analyzes cellular dynamics in archaea, bacteria, and eukaryotes. Her work includes projects on kinetochore architecture, type-III secretion systems, CRISPR-Cas dynamics, and bacterial physiology. She has pioneered methods like TARDIS (Temporal Analysis of Relative Distances) and contributed to open-source software like EVE for event-based microscopy analysis. Her team includes doctoral researchers, master’s students, and technical assistants working on cutting-edge imaging technologies. Recent highlights include combining single-molecule and expansion microscopy for nanostructural visualization and developing drift-correction algorithms. She advocates for equitable research funding models and innovative academic structures.

• Virology
• Microbiology
• Cell Biology
• +۳ مورد دیگر

Dr. Katharina Scherer is a Research Fellow leading an independent research group at the Institute of Microbiology and Biotechnology , University of Bonn, funded by the NRW Returning Scholars Programme. Her work focuses on understanding viral infection dynamics, particularly enveloped viruses like coronaviruses, herpesviruses, and influenza viruses. She employs high-resolution light microscopy techniques to visualize and quantify virus-host interactions, viral assembly mechanisms, and cellular remodeling during infection. Key projects include developing fluorescent reporter systems and expansion microscopy to study SARS-CoV-2 and HSV-1 replication cycles. Her group collaborates internationally, recruiting PhD students in microbiology, cell biology, and biophysics to advance virus-based vaccine optimization and medical applications. Research highlights include: Development of tools for spatiotemporal analysis of HSV-1 replication using dual fluorescent markers. Investigation of Golgi fragmentation and mitochondrial dynamics during viral assembly. Applications of expansion microscopy and light sheet microscopy for 3D imaging of infected cells. Her team actively explores interdisciplinary methods to bridge virology, cell biology, and biophysics, with emphasis on clinically relevant outcomes like vaccine design and antiviral strategies.

Joerg Enderleinمشاهده پروفایل

استاد

• Biophysics
• Single Molecule Spectroscopy
• Super-resolution Microscopy
• +۷ مورد دیگر

Prof. Jörg Enderlein is a physics professor at the Third Institute of Physics (Biophysics) within the Faculty of Physics at Georg-August University in Göttingen. He serves as founding Editor-in-Chief of Biophysical Reports (Biophysical Society) and has secured a prestigious 5-year ERC Advanced Grant since 2021. His research focuses on Single Molecule Spectroscopy and Super-resolution Microscopy, with broader interests extending to crystallography, hydrodynamics, electrodynamics, and general relativity. Recent work highlights advancements in microscopy techniques (e.g., image scanning microscopy, metal-induced energy transfer spectroscopy) and membrane dynamics studies. Key contributions include lipid bilayer analysis, viral-based 3D-bio-nano rulers, and protocols for sub-nanometer resolution imaging. His group collaborates globally, hosting researchers like Dr. Arindam Ghosh (Carl Zeiss Young Investigator Award winner) and Dr. Manoj Kumbhakar (Humboldt Fellow). Notable achievements include ERC funding and editorial leadership. Ongoing projects involve extreme-resolution imaging for structural biology and novel upconversion luminescent particles. The group actively advises PhD students in single-molecule spectroscopy, biophysical applications, and nanoscale dynamics.

Stefan Hellمشاهده پروفایل

استاد

• Nanophotonics
• Biophotonics
• Optical Microscopy
• +۳ مورد دیگر

Prof. Stefan Hell is a renowned physicist and director at the Max Planck Institute for Multidisciplinary Sciences, leading the Department of NanoBiophotonics. He holds positions as Hon. Prof. at the University of Göttingen's Faculty of Physics and has directed multiple research departments since 2002. His work pioneered breakthroughs in super-resolution microscopy, including STED, RESOLFT, and MINFLUX nanoscopy, enabling nanometer-scale imaging in biology and materials science. Education: He earned a Physics Diploma (1987) and Doctorate (1990, summa cum laude) from Heidelberg University, followed by postdoctoral work at EMBL (1991–1993). He habilitated in Physics at Heidelberg in 1996. Research focuses on developing fluorescence nanoscopy techniques that surpass the diffraction limit, with applications in cellular and molecular imaging. His group's innovations have revolutionized biological research by enabling visualization of sub-cellular structures at unprecedented resolutions. Key awards include the Nobel Prize in Chemistry (2014) and the Kavli Prize in Nanoscience (2014). His work has been published in top journals like Science, Nature, and Proceedings of the National Academy of Sciences. He advises researchers in his lab and collaborates internationally. His research groups are affiliated with the Max Planck Institutes in Göttingen and Heidelberg, focusing on advancing optical nanoscopy and its biomedical applications. Labs/Teams: Head of the NanoBiophotonics department and Optical Nanoscopy division, advancing MINFLUX-based technologies and stochastic single-molecule imaging.

Shuhan Jiangمشاهده پروفایل

پژوهشگر ارشد

• Extracellular Vesicles
• Preeclampsia
• Interferometric Scattering Microscopy (iSCAT)
• +۷ مورد دیگر

Shuhan Jiang is a Postdoctoral Researcher at the Max Planck Institute for the Science of Light (MPL) in Erlangen, Germany, affiliated with the Department of Guck Marquardt and the Department of Sandoghdar. Her work focuses on advanced biophysical methods to study extracellular vesicles, particularly in the context of pregnancy-related disorders. Her educational background includes: Medical Degree, Guangzhou Medical University, China (2013–2018) MSc in Reproductive & Developmental Biology, Imperial College London, UK (2018–2019) DPhil, University of Oxford, under Prof. Manu Vatish, focusing on placental extracellular vesicles in preeclampsia Her research centers on extracellular vesicles , particularly placental small extracellular vesicles (sEVs) and their role in preeclampsia . She utilizes interferometric scattering microscopy (iSCAT) to characterize vesicle dynamics and interactions with recipient cells. Her work bridges clinical obstetrics and biophysical innovation, aiming to develop early diagnostic tools for pregnancy complications. The recent publications highlight a strong trend in translational reproductive medicine , with a focus on identifying biomarkers for early-onset preeclampsia using minimal serum samples. Her work also extends into clinical trial methodology, particularly in oncology, where she has contributed to analyses of assessment bias in phase III trials. Scientific contributions include: Development of ExoCounter assays for early preeclampsia detection Identification of novel protein biomarkers in syncytiotrophoblast-derived EVs Investigation of STB-EV dynamics in maternal-fetal communication Methodological contributions to clinical trial assessment reliability She has not been listed with formal advisees or grants in the provided text. However, her research is conducted within collaborative teams at the University of Oxford and the Max Planck Institute for the Science of Light, where she works in a group led by Prof. Vahid Sandoghdar, a leader in biophotonics and single-molecule detection.

• Plant Cell Biology
• Plant Immunity
• Cell Signaling
• +۴ مورد دیگر

Prof. Julien Gronnier is a Professor of Plant Cell Biology at the Technical University of Munich (TUM), affiliated with the TUM School of Life Sciences. His research focuses on plant immunity, development, and evolution, employing multidisciplinary approaches such as genetics, biochemistry, live-cell imaging, and super-resolution microscopy. He investigates the spatial and temporal regulation of membrane-based molecular events, particularly in immune signaling and cell-to-cell communication. Prof. Gronnier completed his PhD in cell biology at the Laboratoire de Biogénèse Membranaire (CNRS) and conducted postdoctoral research at the Sainsbury Laboratory and University of Zurich under Prof. Cyril Zipfel. In 2021, he founded the NanoSignaling Lab at the Center for Molecular Biology of Plants (ZMBP, Tübingen) before joining TUM in 2024. His work has led to key insights into plasma membrane nanodomains and their roles in plant immunity and development. Notable achievements include the EMBO Long-term Fellowship (2021) and the Monique Garnier-Semancik award (2017). His research group develops innovative tools like the OneFlowTraX software for super-resolution analysis, advancing understanding of single-molecule dynamics in plant cells. Key research themes include the regulation of immune receptor kinases, plant peptide hormones, and the interplay between membrane organization and viral infection. His lab explores how nanoscale membrane structures influence cellular processes, with implications for plant health and agricultural resilience.