Christian Eggeling

Prof. Dr. Christian Eggeling is the Head of the Biophysical Imaging Research Department at the Leibniz Institute of Photonic Technology (Leibniz-IPHT). His work bridges advanced optical techniques with cellular biophysics, focusing on nanoscale imaging and molecular dynamics in biological systems.

• Institution: Leibniz Institute of Photonic Technology (Leibniz-IPHT)
• Role: Professor and Department Head

Research interests include:

• Super-resolution microscopy (STED, dSTORM)
• Single-molecule tracking and fluorescence correlation spectroscopy (FCS)
• Biophysical characterization of cellular structures (lipids, proteins, extracellular vesicles)
• Development of novel imaging technologies (iSCAT-TIRF, PiF-IR)

Recent publications highlight his group's innovations in:

• Overcoming photoconversion artifacts in confocal/STED microscopy
• Combining organ-on-chip models with imaging to study gut-lung axis interactions
• Quantifying candidalysin neutralization as a therapeutic strategy for vulvovaginal candidiasis
• Advancing iSCAT and PiF-IR for nanoparticle tracking and protein structure analysis
• Optimizing membrane vesicle production methods for biomedical applications

Technical focus spans optical engineering, computational data processing (e.g., neural networks for artifact correction), and interdisciplinary applications in virology, immunology, and cellular biophysics.