جست‌وجوی استاد و پژوهشگر

Melanie Brinkmannمشاهده پروفایل

استاد

• Virology
• Innate Immunity
• Immune Evasion
• +۴ مورد دیگر

Professor Melanie Brinkmann is a leading virologist and immunologist at Technische Universität Braunschweig and the Helmholtz Centre for Infection Research (HZI) . She has served as head of the research group "Virology and Innate Immunity" at HZI since 2010 and became a professor at TU Braunschweig's Institute of Genetics in 2018. Her academic training includes biology studies at Georg-August University Göttingen, Humboldt University Berlin, and Imperial College London, followed by a PhD at Hannover Medical School and postdoc work at MIT's Whitehead Institute. Research Focus: Her work explores how herpesviruses (e.g., KSHV, CMV) and other pathogens manipulate innate immune responses, particularly through interferon signaling and pattern recognition receptors. Leadership Roles: She co-chaired Germany's SARS-CoV-2 Pandemic Expert Advisory Group (2021-2023), serves on the DFG Review Board (2024), and founded the Infect-Net network for female infection researchers. Scientific Awards: Recognized with the ScienceHero Prize (2022) for pandemic communication, Robert Koch Postdoctoral Award (2007), and others.

Sam Robinsonمشاهده پروفایل

پژوهشگر ارشد

• Basic pharmacology
• Biological Sciences
• Biomedical and Clinical Sciences
• +۹ مورد دیگر

Dr. Sam Robinson is a Senior Research Fellow at the University of Queensland's Institute for Molecular Bioscience (IMB) and an Affiliate of the Centre for Innovation in Pain and Health Research (CIPHeR) within the Faculty of Health, Medicine and Behavioural Sciences. His research focuses on the discovery and characterization of novel toxins from venomous animals and plants, with applications in understanding pain mechanisms and developing new therapeutics. Doctor of Philosophy, Monash University Dr. Robinson's research expertise spans multiple disciplines including pharmacology, neuroscience, physiology, organismal biology, medicinal chemistry, biochemistry, molecular biology, proteomics, and structural biology. His work centers on plant and animal toxins, particularly those causing pain, with applications in understanding chemical defense mechanisms and developing treatments for chronic pain and diabetes. He investigates the structure, function, and pathophysiology of stings from various organisms including ants, wasps, scorpions, spiders, cone snails, and stinging plants. His recent publications demonstrate a strong focus on venom evolution, pain mechanisms, and toxin characterization, with particular emphasis on sodium channel modulation, venom composition across species, and the biomedical applications of natural toxins. His work frequently appears in high-impact journals including Nature Communications, Science, and PNAS. Dr. Robinson has received significant research funding including an NHMRC Investigator Grant (2023-2027) for 'New Toxin Tools for Dissecting Pain', ARC Discovery Projects, and National Geographic Society grants. He actively supervises multiple PhD students working on venom evolution, pain-causing toxins, and sodium channel research. As a media expert, he is frequently consulted on topics related to ants, bees, cone snails, stings, toxins, venom, and wasps.

Paul Eggletonمشاهده پروفایل

استاد

• Innate and adaptive immunity
• Autoimmune diseases
• Neuroinflammation
• +۶ مورد دیگر

Dr. Paul Eggleton is an Honorary Professor of Immunology at the University of Exeter Medical School and Vice President of Immunology at Revolo Biotherapeutics . With academic affiliations spanning University of Oxford , Boston University , and University of Alberta , he has led groundbreaking research in innate immunity , neuroinflammation , and chaperone protein immunobiology . Trained at Royal Free Hospital School of Medicine and Royal College of Surgeons Postdoctoral work: MRC Immunochemistry Unit (Oxford), Boston University His work has redefined understanding of ER chaperones in immunomodulation, particularly calreticulin 's extracellular functions in cancer cell death and autoimmune pathogenesis. He co-discovered the lectin pathway of complement activation and identified CD20+ T cell subsets in multiple sclerosis and rheumatoid arthritis. Current research at UCB Pharma and Revolo Biotherapeutics focuses on: Neuroinflammation in CNS disorders Immunomodulatory peptides like IRL201104 Stress pathways (cGAS-STING) in neurodegeneration Scientific contributions: MRC and ARC funded fellowships Over 200 peer-reviewed publications Key discoveries in calnexin-Fabp5 complex , CD200 regulation , and oxidative autoantigen modifications His academic leadership included serving as Immunology Curriculum Lead (2008-2017) and establishing the 11th International Calreticulin Workshop. He supervises students like Emma Charlton and collaborates with teams across University of Alberta , Cambridge , and Oxford .

Modi Wangمشاهده پروفایل

استادیار

• Microbial Genetics
• Inter-kingdom Communication
• Noninvasive Bacterial Detection
• +۳ مورد دیگر

Modi Wang is an Assistant Professor in the Department of Chemistry & Biochemistry at Clarkson University's Coulter School of Engineering & Applied Sciences. She leads a research program investigating microbial genetics, inter-kingdom communication, novel antibiotic discovery, and noninvasive bacterial detection technologies. Her lab employs biochemical and cell biological approaches to study bacterial signaling pathways and develop therapeutic strategies. Wang's research focuses on: cGAS-STING pathway regulation and immunomodulation Cyclic dinucleotide signaling in host-pathogen interactions Development of RF-based bacterial detection methods Anticancer and antimicrobial drug discovery Her publications demonstrate expertise in biochemical assay development, proteomic analysis, and medicinal chemistry. Recent work explores chloride ion homeostasis in immune signaling and phosphoproteomic changes induced by cyclic dinucleotides. The Wang Lab maintains active investigations into small molecule inhibitors targeting bacterial signaling and cancer pathways. Current lab members include doctoral student Colby Hladun, with ongoing recruitment for additional graduate researchers.

• Immunology
• Virology
• Host-Microbe Interactions
• +۷ مورد دیگر

Miyu Moriyama is an Associate Research Scientist in the Department of Immunobiology at Yale School of Medicine. She is a key member of the Iwasaki Lab, where she conducts cutting-edge research on host immune responses to respiratory viruses such as influenza and SARS-CoV-2. Her work integrates molecular virology, immunology, and microbiome science to understand mechanisms of antiviral defense and immune evasion. Her research interests include: Host-microbe interactions in antiviral immunity Inflammasome and pyroptosis pathways Mucosal immunity in the respiratory tract Impact of environmental factors (e.g., temperature) on immune responses Immune evasion by SARS-CoV-2 variants The analysis of her recent publications reveals a consistent focus on innate immune mechanisms, particularly how viral components modulate host defenses. Her work spans from fundamental discoveries in inflammasome activation to translational insights into vaccine design and diagnostic strategies. She frequently publishes in top-tier journals such as Nature , Science , and PNAS , often in collaboration with leading immunologists. Her scientific contributions have not been accompanied by publicly listed awards in the provided text, but her extensive publication record and high-impact collaborations underscore her significant role in the field. Dr. Moriyama mentors and collaborates within a vibrant research team at Yale, contributing to both independent projects and large-scale collaborative efforts. She has no listed advisees in the provided data. Her laboratory work is centered in the Iwasaki Lab, a leading center for translational immunology and viral pathogenesis research.

Dirk Hallerمشاهده پروفایل

استاد

• Nutritional Science
• Immunology
• Microbiome Research
• +۳ مورد دیگر

Prof. Dirk Haller is a leading academic at the Technical University of Munich (TUM), serving as Chair of Nutrition and Immunology and Director of the Central Institute for Food & Health (ZIEL). His research focuses on the interplay between gut microbiota, chronic inflammatory diseases (e.g., Crohn's disease), and cancer. He holds leadership roles in major research initiatives, including the DFG Collaborative Research Center SFB1371 ('Microbiome Signatures'), and has pioneered gnotobiotic mouse models to study microbiome-host interactions. Education : Double degree from the University of Hohenheim Doctorate in Food Microbiology and Nutritional Science Postdoctoral research at ETH Zurich and the University of Alberta Research Interests : Haller's work explores microbiome-driven mechanisms in disease pathogenesis, including: Microbial dysbiosis and inflammatory responses Bile acid metabolism and cancer progression Circadian rhythm regulation of microbiota Clinical applications of microbiome modulation (e.g., exclusive enteral nutrition in pediatric Crohn's) Awards & Recognition : Heinz Maier-Leibnitz Medal (2020) Main Prize of the German Society for Hygiene and Microbiology (2015) ERC Review Panel Head for Consolidator Program (2015, 2017) Grants & Leadership : Haller oversees national and international programs, including DFG Priority Program SPP1656 and SFB1371. His lab collaborates globally on translational research initiatives linking microbiome science to clinical outcomes in immunology and oncology. Labs/Teams : Haller's research groups at TUM's ZIEL integrate microbiology, immunology, and systems biology to address complex diseases like IBD and colorectal cancer.

Petr Brozمشاهده پروفایل

استاد

• Innate Immunity
• Host-Pathogen Interactions
• Inflammasome Biology
• +۷ مورد دیگر

Petr Broz is a Full Professor in the Department of Biochemistry at the Faculty of Biology and Medicine, University of Lausanne (UNIL), where he has been a faculty member since 2017, first as Associate Professor and promoted to Full Professor in 2022. His research focuses on the molecular mechanisms of innate immunity, particularly inflammasome activation and host defense against bacterial pathogens such as Salmonella typhimurium and Francisella tularensis . Appointed Full Professor, UNIL, 2022 Associate Professor, UNIL, 2017–2022 Assistant Professor, Biozentrum, University of Basel, 2013–2017 Postdoctoral Fellow, Stanford University, 2008–2012 PhD in Microbiology, University of Basel, 2006 MSc in Biology, University of Basel, 2002 Dr. Broz’s research explores how the innate immune system detects bacterial pathogens and mounts defensive responses. His work investigates inflammasome assembly, regulation, and function, particularly in the context of interferon signaling and CRISPR/Cas9-based genetic screens. He uses advanced molecular and cellular techniques to dissect host-pathogen interactions and identify novel immune regulators. The 15 most recent publications highlight a strong focus on inflammasome biology, pyroptosis, interferon signaling, and bacterial immune evasion. These works span high-impact journals such as Nature , Science , Nature Immunology , and PNAS , demonstrating consistent contributions to immunology and infection biology. Key themes include the spatiotemporal regulation of inflammasomes, the role of gasdermin D in cell death, and the interplay between interferon responses and inflammasome activation. Scientific awards and recognition include: EMBO Young Investigator (2015) Friedrich Miescher Award (2016) He has received multiple grants from the Swiss National Science Foundation (SNSF) and an ERC Consolidator Grant, supporting his innovative research. Dr. Broz is actively involved in mentoring and has supervised numerous PhD students, master’s students, and postdoctoral fellows. His laboratory integrates genomic, biochemical, and immunological approaches to uncover fundamental mechanisms of immune defense. He is also engaged in undergraduate and postgraduate teaching at UNIL. His research team operates at the forefront of molecular immunology, utilizing cutting-edge technologies such as CRISPR screening and live-cell imaging to study host defense mechanisms in real time. The lab collaborates with national and international partners to advance understanding of infectious diseases and inflammatory processes.

Andrea Ablasserمشاهده پروفایل

استاد

• Innate Immunity
• Molecular Immunology
• Cellular Biology
• +۷ مورد دیگر

Andrea Ablasser is a Full Professor at École polytechnique fédérale de Lausanne (EPFL), affiliated with the School of Life Sciences, the Global Health Institute (GHI), and the Department of Molecular and Cellular Biology. She leads the Ablasser Lab, focusing on innate immunity and host defense mechanisms. Her research centers on the molecular basis of pathogen detection, particularly the cGAS-STING signaling pathway, which is crucial in immunity against infections and cancer. Her work spans nucleic acid sensing, inflammatory regulation, aging-related inflammation, and autoimmune disorders. Recent studies explore mitochondrial DNA-driven inflammation, epigenetic regulation of immune responses, and the role of cGAS-STING in neurodegeneration. The trends in her recent publications show a strong focus on innate immune signaling, with recurring themes in cGAS/STING regulation, nucleic acid sensing, and immune homeostasis. Her work combines molecular biology, cell biology, and translational approaches, often published in high-impact journals like Nature , Science , and Nature Immunology . Andrea Ablasser has been honored with several prestigious awards, including: Paul Ehrlich and Ludwig Darmstaedter Prize 2025 Liliane Bettencourt Prize for Life Sciences Clarivate Highly Cited Researcher 2024 She mentors multiple PhD students and is actively involved in academic governance as a member of the EPFL Academic Strategic Committee and the Doctoral Program in Molecular Life Sciences. She contributes to teaching through courses such as Immunology - advances and therapeutic implications and practical lab instruction. Her lab is supported by competitive research funding, reflecting its impact in immunology and molecular medicine.

Michelle H. Theusمشاهده پروفایل

استاد

• Neurotrauma
• Neuroinflammation
• Eph Receptor Signaling
• +۷ مورد دیگر

Michelle H. Theus is a Professor of Molecular and Cellular Neurobiology at the Department of Biomedical Sciences and Pathobiology , Virginia-Maryland College of Veterinary Medicine, Virginia Tech. She serves as Director of the Neurotrauma Research Program and co-director of the Translational Biology, Medicine, and Health Graduate Program. Education: PhD in Neuropathology and Laboratory Medicine (2006), Medical University of South Carolina; Board Certifications in Clinical Laboratory Science and Histocompatibility Research Focus : Her work investigates Eph receptor signaling in neurovascular and neuroimmune responses after brain injury. Key areas include cerebrovascular remodeling, neuroinflammation, neurogenesis, and therapeutic peptide development for post-traumatic epilepsy and stroke recovery. Publications (2022-2025) emphasize single-cell transcriptomics of immune responses STING signaling in microglia EphA4’s role in efferocytosis collateral vessel mechanisms in stroke Her lab employs murine models and advanced imaging to study neurovascular integrity and innate immunity modulation. Grant Funding includes multiple NIH R01 awards (2019-2026) targeting age-dependent immunity in TBI, inflammation suppression, and stroke-related arteriogenesis.

Nicholas Mathesonمشاهده پروفایل

پژوهشگر

• Immunometabolism
• Host-Pathogen Interactions
• Proteomics
• +۵ مورد دیگر

Dr. Nicholas Matheson is a researcher at the University of Cambridge's Department of Medicine and a collaborator in the Cambridge Immunology Network. His work focuses on understanding how viruses like HIV and SARS-CoV-2 manipulate host immunometabolism through protein regulation and proteomic analysis. Research Focus: Using SILAC and TMT-based proteomics, Matheson investigates how HIV accessory proteins (Vpu, Nef) modulate cell surface nutrient transporters to alter metabolic flux in infected cells. His studies extend to SARS-CoV-2 research, including viral entry mechanisms, immune response heterogeneity, and Long Covid pathogenesis. Collaborative Themes: His work spans Host-pathogen interactions in T cells CRISPR-Cas9 functional genomics Immunometabolic regulation Extracellular vesicle biology Viral entry mechanisms (TMPRSS2, ACE2)

Konrad Adenمشاهده پروفایل

استاد

• Immunometabolism
• Inflammatory Bowel Disease (IBD)
• Metabolomics
• +۵ مورد دیگر

Konrad Aden is a Professor at Kiel University and a senior physician at the Department of Internal Medicine I, University Medical Center Schleswig-Holstein (UKSH). He leads the Junior Research Group for Immunometabolism of Intestinal Inflammation and Systems Immunology at the Institute of Clinical Molecular Biology (IKMB), focusing on translating findings from clinical research and basic science into innovative IBD diagnostics and therapies. Key roles: Principal Investigator (Project 7), BMBF Juniorverbund Try-IBD coordinator Research areas: Immune-metabolic crosstalk in IBD, microbiome therapeutics, tryptophan and serine metabolism, systems immunology His publications address metabolomic signatures in IBD, microbial interactions in chronic inflammation, and immune signaling pathways like cGAS-STING and JAK-STAT. Awards include the Else Kröner Clinician Scientist Professorship. He collaborates extensively with working groups at IKMB and employs preclinical models (organoids, DSS colitis) alongside clinical biobanks for translational research.

Li-Yen Mae Huangمشاهده پروفایل

استاد

• Chronic Pain
• Nociception
• Neuroinflammation
• +۳ مورد دیگر

Li-Yen Mae Huang, PhD, is a Professor in the Department of Neurobiology at the University of Texas Medical Branch (UTMB). Her laboratory investigates molecular mechanisms of chronic pain, focusing on neuroplasticity in dorsal root ganglion neurons, purinergic signaling, and neuron-glial interactions after injury. She utilizes rodent and large animal (sheep) models to bridge preclinical findings with clinical applications in pain management. Education: PhD in Biophysics, State University of New York at Buffalo Post-Doctoral Training: Laboratory of Biophysics and Neurophysiology, NINDS, NIH Visiting Scientist: Max-Planck-Institut für Biophysical Chemistry, Germany Research Focus: Dr. Huang's work explores ATP-mediated neuron-satellite glial communication, P2X receptor sensitization in neuropathic pain, inflammatory hyperalgesia, and opioid analgesia mechanisms. Her lab also validates rodent-derived pain insights in translational sheep models to enhance clinical relevance. Publication Trends: Recent articles (2020-2025) reflect interdisciplinary collaboration, spanning neurobiology, diabetes complications, cancer mechanisms, and nanomaterials. Key themes include neuro-immune interactions, diabetic encephalopathy, and innovative photocatalytic materials for energy applications.

Sze Chun Winson Hoمشاهده پروفایل

دانشیار

• Pediatric Neurosurgery
• Cancer Immunotherapy
• Protein Phosphatase 2A (PP2A) in Tumor Immunity
• +۳ مورد دیگر

Dr. Sze Chun Winson Ho is an Associate Professor in Neurological Surgery at the University of California, San Francisco (UCSF) School of Medicine. A board-certified pediatric neurosurgeon, he specializes in treating children with brain tumors, epilepsy, and trauma while advancing novel immunotherapies in his laboratory. MD: Yale School of Medicine (2011) Residency: University of Virginia/NIH Neurosurgery Program (2018) Fellowship: University of Utah Pediatric Neurosurgery (2019) His research focuses on Protein Phosphatase 2A (PP2A) modulation for enhancing tumor immunogenicity in medulloblastoma and glioblastoma. Recent publications emphasize: PP2A deficiency in senolytic treatment sensitization STING pathway activation for immune response Mitochondrial dysfunction in glioblastoma Laser interstitial thermal therapy applications Scientific appointments and funding include: NIH/NINDS K12 Award Rally Foundation Independent Investigator Grant Corey Raffel Endowed Professorship (UCSF) NIH R01 Grant (2023-2028)

Chinmay Trivediمشاهده پروفایل

استاد

• Histone Deacetylases
• Cardiac Development
• Congenital Heart Disease
• +۷ مورد دیگر

Dr. Chinmay Trivedi is a Professor of Medicine at UMass Chan Medical School , with additional affiliations in Molecular, Cell and Cancer Biology, and Translational Science programs. His research focuses on elucidating chromatin-modifying mechanisms in congenital cardiovascular and lymphatic diseases. Director, Division of Cardiovascular Medicine Research Research Director, Translational Science Program (Morningside Graduate School) Principal Investigator in Trivedi Lab Research Highlights: His laboratory established causal links between: Hdac3 mutations and Emberger syndrome (lymphedema) through non-coding DNA element analysis KRAS/BRAF mutations and hepatic vascular cavernomas with RAS-MAPK1 pathway inhibition as treatment Hdac1/Hdac2 roles in cryptic transcription suppression during cardiogenesis Tbx5-Hdac3 interactions in Holt-Oram syndrome pathogenesis YAP1 activation in vascular tumor epithelioid hemangioendothelioma Publication Trends show consistent work across Journal of Clinical Investigation , Science Advances , and Circulation Research , with recent emphasis on: Epigenetic regulation of cardiovascular development Signaling pathway modulation in lymphatic diseases Translational models for congenital defects Metabolic basis of cardiac pathologies Training Opportunities: The lab offers rotation projects for graduate students and postdoctoral positions requiring expertise in: Murine models ChIP-seq and epigenetic analysis Biochemical signaling assays Translational biology techniques Key Concepts: Histone deacetylases, non-coding DNA, RAS-MAPK1 pathway, oscillatory shear stress, cryptic transcription, enhanceosome complexes

Megan O'Connorمشاهده پروفایل

استادیار

• Virology
• Immunology
• HIV and Co-infections
• +۴ مورد دیگر

Megan O'Connor serves as Research Assistant Professor in the Department of Microbiology at the University of Washington and holds a Core Scientist position at the Washington National Primate Research Center. Her research bridges virology, immunology, and microbiome science through nonhuman primate models of human disease. Her academic journey includes: Bachelor's degree from University of California, Berkeley PhD in Immunology from Geisel School of Medicine at Dartmouth under Dr. William Green Postdoctoral training at University of Washington with Dr. Deborah Fuller Dr. O'Connor's research program systematically investigates viral co-infections in HIV contexts through four integrated pillars: Risk assessment of emerging pathogen co-infections Characterization of novel immune pathways in pathogenesis Microbiome alterations during disease progression Pre-clinical evaluation of vaccines and therapeutics Her work leverages nonhuman primate models to address critical gaps in understanding how immunocompromised states alter infection dynamics and treatment responses. Analysis of her publication record reveals dominant research trajectories centered on SIV/HIV co-infection models with emerging viruses including SARS-CoV-2 and Zika virus. Key thematic clusters include viral shedding dynamics, mucosal immunity disruption, microbiome-virus interactions, and vaccine durability assessment. Her methodological approach consistently integrates molecular virology with systems immunology in translational primate models. As Principal Investigator of the O'Connor Lab, she implements a structured mentorship philosophy emphasizing: Rigorous scientific methodology Individualized career development Inclusive research environment cultivation Her team currently includes research technicians Zo Kolodner and Semira Beraki, with documented emphasis on developing future scientific leaders through hands-on research experience.