جستجوی استاد راهنمای دانشگاهی

• Molecular Biology
• Biochemistry
• Cancer Genomics
• +۶ مورد دیگر

Reuben Harris is a Professor in the Department of Biochemistry, Molecular Biology, and Biophysics at the University of Minnesota Medical School. His research spans multiple disciplines including molecular biology, biochemistry, virology, and cancer genomics, with a particular focus on APOBEC enzymes and their roles in both antiviral defense and cancer development. Dr. Harris's research interests center on the APOBEC family of DNA deaminases, particularly their dual roles in antiviral immunity (especially against HIV) and cancer mutagenesis. His work explores how these enzymes catalyze DNA deamination, the structural and biochemical mechanisms that regulate their activity, and how their mutagenic potential contributes to tumor evolution in various cancers including breast, ovarian, and other malignancies. His research has significant implications for understanding viral restriction mechanisms and developing novel cancer therapeutics targeting APOBEC-mediated mutagenesis. Analysis of his recent publications reveals a consistent focus on APOBEC3 enzymes (particularly APOBEC3A, APOBEC3B, and APOBEC3G), with increasing attention to their structural biochemistry, DNA sequence context preferences, and therapeutic targeting. His work bridges basic enzymology with clinical applications, particularly in cancer genomics and antiviral research, demonstrating how fundamental biochemical insights can inform therapeutic strategies for cancer and viral infections. Dr. Harris has been Principal Investigator on numerous significant research grants, including the Midwest AViDD Center funded by the NIH National Institute of Allergy and Infectious Diseases (2022-2025), projects on APOBEC3B and DNA repair in ovarian cancer funded by the Ovarian Cancer Research Fund (2021-2022), and research on APOBEC mutagenesis in breast cancer funded by Memorial Sloan Kettering Cancer Center and the NIH National Cancer Institute (2020-2022). He also serves as a Co-Investigator on the Department of Defense project targeting N-Myc in neuroblastoma with Aurora kinase A degraders (2021-2025). His laboratory is part of a robust collaborative network focused on DNA repair mechanisms, cancer genomics, and antiviral defense. The research group works closely with structural biologists, computational biologists, and clinical researchers to translate basic findings into potential therapeutic applications. Current projects emphasize understanding how mesoscale DNA features influence APOBEC activity, developing quantitative assays for DNA deamination, and exploring synthetic lethal approaches targeting APOBEC-expressing cancers.

Trung Nghia Vuمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۵ مورد دیگر

Trung Nghia Vu is a Principal Researcher at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet in Stockholm, Sweden. His research group focuses on developing and applying statistical and bioinformatics methods for molecular biology and medicine, with particular emphasis on cancer genomics and pharmacogenomics. Dr. Vu received his PhD from the Department of Mathematics and Computer Science at the University of Antwerp, Belgium (2009-2014), following an MSc in Computer Engineering from Korea Aerospace University (2006-2008) and a BSc in Technology from Vietnam National University in Hanoi (2000-2004). His research focuses on developing statistical and bioinformatics methodologies for analyzing high-throughput omics data, with specific interests in single-cell sequencing analysis, characterization of cancer omics, and pharmacogenomics. His group has developed 20 statistical and bioinformatics tools available through Biostat Wiki Primary research areas include gene/isoform quantification, detection of abnormal RNAs, single-cell RNA-seq analysis, and drug response prediction Current projects focus on breast cancer and Acute Myeloid Leukemia (AML) Analysis of Dr. Vu's recent publications reveals a strong focus on cancer genomics, particularly in AML and breast cancer. His work bridges computational biology with clinical applications, developing methods for spatial transcriptomics, drug synergy prediction, and circular RNA analysis. The research demonstrates a clear trajectory toward precision medicine applications, with increasing emphasis on personalized drug response prediction and pathway activation modeling. Dr. Vu actively supervises multiple students and researchers, including both completed PhD students (Quang Thinh Trac, Lu Pan, Wenjiang Deng) and ongoing supervisees (Gulser Caliskan, Meghana Alugunoolla, Yuying Li, Aron Arzoomand). His research is supported by significant grants from the Swedish Research Council, CancerFonden, and Karolinska Institutet. He leads the Computational Medicine and Bioinformatics research group at Karolinska Institutet, which collaborates with international clinical and systems-biology researchers. The group maintains active development of bioinformatics tools and maintains the Biostat Wiki platform for academic use. Dr. Vu also contributes to teaching through master's and doctoral courses in biostatistics and R programming at Karolinska Institutet.

• Neuromodulation
• Transcranial Magnetic Stimulation
• Deep Brain Stimulation
• +۴ مورد دیگر

Lothar Krinke serves as an Adjunct Assistant Professor at West Virginia University School of Medicine with dual appointments in the Department of Neuroscience and the Rockefeller Neuroscience Institute. He concurrently holds executive leadership as CEO of Magstim Inc., a transcranial magnetic stimulation technology company, and serves on the Board of the UCLA Brain Mapping Medical Research Organization, demonstrating significant integration of academic research with industry innovation in neuromodulation. His educational foundation includes: PhD in Molecular Biology from the University at Albany, State University of New York Dr. Krinke's research program spans two distinct yet complementary domains: contemporary neuromodulation therapies and foundational molecular biology. His current work focuses on advancing transcranial magnetic stimulation (TMS) technology, particularly navigated TMS systems for substance abuse disorders, chronic pain, OCD, and dementia. He actively pursues closed-loop TMS development using neurophysiological biomarkers for patient stratification. His historical research contributions center on RNA-mediated gene regulation mechanisms in bacteriophage lambda, establishing expertise that bridges molecular neuroscience and clinical applications. Analysis of his publication record reveals a clear evolution from molecular biology (1987-1991) to clinical neuromodulation (2016-2022). Recent work emphasizes collaborative, interdisciplinary approaches to psychiatric neurosurgery and neuromodulation technology development, with strong representation in consensus-building initiatives like the Deep Brain Stimulation Think Tank. His research consistently addresses translational challenges in moving neuromodulation from laboratory to clinical practice. No scientific awards or fellowships are documented in the available materials. While specific student mentorship details are not provided, Dr. Krinke's leadership roles indicate significant involvement in research direction and team building. His position as CEO of Magstim Inc. suggests substantial engagement with research commercialization and technology development funding, though specific grant details are not disclosed in the source material. Dr. Krinke's primary research infrastructure includes Magstim Inc., where he drives TMS technology innovation, and the UCLA Brain Mapping Medical Research Organization, facilitating large-scale neuroimaging collaborations. His work environment integrates academic neuroscience departments with industry R&D, creating a unique ecosystem for accelerating neuromodulation therapies from concept to clinical implementation.

Anna Hagström-Anderssonمشاهده پروفایل

مدرس ارشد

• Leukemia
• MLL Gene Rearrangements
• Epigenetics
• +۵ مورد دیگر

Anna Hagström-Andersson is a Senior Lecturer at the Division of Clinical Genetics , Lund University , and a Principal Investigator at the Lund University Cancer Centre (LUCC) . She leads research teams focused on the pathogenetic mechanisms of MLL-rearranged acute leukemia in infants , aiming to improve therapeutic approaches through genomic and epigenetic studies. Her research employs high-resolution genomic methods and murine models to investigate genetic lesions , clonal cooperation , and relapse dynamics in pediatric leukemia. She contributes to UN Sustainable Development Goals related to Cancer and Oncology and Basic Cancer Research . Current Projects : "Spädbarn och leukemi: första mekanismerna bakom leukemogenes tidigt i livet" (Swedish Childhood Cancer Fund, 2025–2027) "The molecular pathogenesis of KMT2A-rearranged leukemia from diagnosis to relapse" (Cancerfonden, 2024–2027) Supervision of PhD candidate M. Pilheden on genome-wide MLL-gene rearrangement studies Research Outputs : 49 publications, including groundbreaking work on clonal evolution , metabolic vulnerabilities , and epigenetic regulation in leukemia. Collaborations : Active in LUCC networks and experimental highlight series seminars.

Garima Bhatiaمشاهده پروفایل

پژوهشگر ارشد

• Plant Pathology
• Molecular Plant-Microbe Interactions
• Grapevine Genetics
• +۳ مورد دیگر

Dr. Garima Bhatia is a Research Fellow at the Australian National University's Research School of Biology within the Division of Plant Sciences. She is an active member of the Pogson Group focusing on chloroplast-to-nuclear signaling mechanisms related to light, drought, and carotenoid pathways. Her office is located in Room 1.028, Level 1 of the Linnaeus Building. Her research centers on molecular plant-pathogen interactions, with specialization in grapevine ( Vitis vinifera ) defense mechanisms against powdery mildew ( Erysiphe necator ) and downy mildew ( Plasmopara viticola ). She employs genome-wide approaches to study NBS-LRR gene families and long non-coding RNAs (lncRNAs) in disease resistance and abiotic stress responses. Her work extends to Brassica juncea (Indian mustard) for heat and drought tolerance mechanisms. Analysis of her 9 publications (2017-2021) reveals consistent focus on plant molecular genetics, with 60% of output addressing fungal pathogen resistance through genomic and transcriptomic approaches. Key trends include lncRNA-mediated regulatory networks (44% of publications) and genome-wide characterization of defense gene families (33%). Dr. Bhatia is registered to supervise research students but no specific advisees are listed in available records. She maintains an active research profile with 333 Scopus citations and an h-index of 9. Her laboratory work within the Pogson Group integrates chloroplast signaling pathways with nuclear gene expression during environmental stresses, utilizing advanced genomic techniques to dissect plant immune responses.

Ludovic Vallierمشاهده پروفایل

استاد

• Stem Cell Biology
• Liver Organogenesis
• Regenerative Medicine
• +۳ مورد دیگر

Prof. Dr. Ludovic Vallier is a Max Planck Fellow and Research Group Leader at the Vallier Lab , affiliated with the Berlin Institute of Health at the Charité (BIH) and the Max Planck Institute for Molecular Genetics (MPIMG) . His lab, established as a satellite group at MPIMG in 2022, focuses on stem cell biology , liver regeneration , and organoid technology for clinical translation. University : Max Planck Institute for Molecular Genetics Department : Vallier Lab Academic Rank : Professor Research Interests : The Vallier Lab investigates human liver development , leveraging human induced pluripotent stem cells (hiPSCs) and primary organoids to model liver diseases and develop cell-based therapies. Their work bridges regenerative medicine , developmental biology , and tissue engineering to address clinical challenges in liver dysfunction. Publication Trends : His recent articles (2023–2025) emphasize organoid applications in liver and pancreatic research, stem cell differentiation , and metabolic or immunological mechanisms in disease contexts. Keywords span Stem Cell Biology , Developmental Biology , and Regenerative Medicine , with sub-fields like hepatic lineage specification , single-cell transcriptomics , and inflammatory reprogramming . Scientific Awards : Max Planck Fellow Lab and Collaborations : The Vallier Lab collaborates closely with MPIMG researchers, utilizing 3D organoid cultures and hiPSC-derived cells to study liver regeneration and disease. Their work aligns with BIH’s mission to translate basic research into clinical therapies for liver disorders.

Daniel Kümmelمشاهده پروفایل

استاد

• Membrane trafficking
• Signal transduction
• Small GTPase regulation
• +۳ مورد دیگر

Daniel Kümmel is University Professor of Biochemistry at the University of Münster , Germany. He heads the Kümmel Group within the Institute of Biochemistry and is an active member of the Cells in Motion Cluster of Excellence, where he contributes to the graduate program CiM-IMPRS. Research Interests span membrane trafficking and signal transduction, with particular emphasis on the regulatory protein complexes of small GTPases. His laboratory combines structural biology—using X-ray crystallography and cryo-electron microscopy—with protein engineering and inhibitor design to elucidate how membrane targeting and vesicular transport are controlled at the molecular level. Recent work has produced the first 3-D structures of key regulatory assemblies such as the Mon1-Ccz1 complex, revealing how Rab7/Ypt7 GTPases are activated on late endosomes and how the TSC complex senses lysosomal lipid signals to regulate mTORC1. Scientific Awards & Honors: Although no specific prizes are listed in the provided text, Prof. Kümmel’s sustained publication record in high-impact journals (PNAS, Nature Communications, Molecular Cell, Structure, Angewandte Chemie) attests to significant recognition by the scientific community. Advising & Funding: He mentors doctoral researchers within the CiM-IMPRS graduate program and participates in collaborative projects funded by the Multiscale Imaging Centre and the Cells in Motion Cluster of Excellence. Laboratory & Collaborations: The Kümmel Group operates state-of-the-art facilities for protein crystallization, cryo-EM, and biochemical reconstitution, collaborating closely with groups led by Christian Ungermann, Stefan Raunser, and Andrea Rentmeister to integrate structural, cell-biological, and chemical-biological approaches.

Michael J. Zillerمشاهده پروفایل

استاد

• Functional Genomics
• Psychiatric Genetics
• Neurobiology of Mental Illness
• +۳ مورد دیگر

Michael J. Ziller is a Professor at the Faculty of Medicine, University of Münster, affiliated with the Department of Psychiatry and Psychotherapy. He leads the Lab for Functional Genomics in Psychiatry and participates in the "Cells in Motion" research commission. Research Focus: Functional genomics, molecular mechanisms of psychiatric disorders (schizophrenia, bipolar disorder), and computational strategies for personalized medicine. Projects: Decoding polygenic risk architectures, modeling neuronal hyperexcitability, and developing machine learning methods for patient stratification. Funding: BMBF (Project DINGS), EKFS Schlüsselproject. The lab utilizes iPSC models, ChIP-Seq, ATAC-Seq, HiC, single-cell RNA-Seq, and Perturb-Seq to bridge genetic associations with neurobiological insights, aiming to identify drug targets and optimize treatment for psychiatric diseases.

Darrell R. Davisمشاهده پروفایل

استاد

• RNA Biology
• Antiviral Therapeutics
• Virology
• +۳ مورد دیگر

Darrell R. Davis serves as Professor of Medicinal Chemistry and Adjunct Professor of Biochemistry at the University of Utah, with primary affiliation in the Department of Medicinal Chemistry and active roles in the Molecular Biology and Biological Chemistry Programs. His educational credentials include a B.S. from the University of Puget Sound and a Ph.D. from the University of Utah, establishing deep institutional roots. Research focuses on RNA structure-function relationships in viral pathogenesis, specifically developing host-targeted antivirals that disrupt viral mRNA translation mechanisms across diverse pathogens including SARS-CoV-2, HCV, and Zika virus. Laboratory work has identified enantiomerically specific compounds like DD011-E2 (EC 50 = 140 nM against SARS-CoV-2) with conserved activity against phylogenetically distant viruses, indicating a novel mechanism targeting cellular processes. Publication analysis reveals consistent emphasis on RNA structural biology applied to antiviral discovery, spanning fundamental tRNA/HIV-1 interactions to translational control elements in HCV IRES. Methodologies integrate molecular dynamics simulations, NMR spectroscopy, and cell-based antiviral assays across all studies, demonstrating interdisciplinary rigor in targeting RNA for therapeutic intervention. No scientific awards are documented in the source material. Dr. Davis leads an active research laboratory (accessible via Lab Page link) with extensive collaborative networks evident in co-authorship patterns, though specific grant details remain unreported. He mentors graduate students in medicinal chemistry and virology, contributing to both the Biological Chemistry and Molecular Biology Ph.D. programs through curriculum development and research supervision. Laboratory infrastructure supports RNA structural analysis and antiviral screening, with current work optimizing lead compounds against pandemic-capable viruses through mechanistic elucidation of host-targeted inhibition pathways.

Anthea Letsouمشاهده پروفایل

استاد

• Developmental Biology
• Neurogenetics
• Molecular Genetics
• +۵ مورد دیگر

Anthea Letsou is a Professor of Human Genetics at the University of Utah, with a research focus on using Drosophila melanogaster to model human developmental and neurodegenerative diseases. Her work spans two primary areas: embryonic morphogenesis and neurometabolic disorders. Education: B.A., Harvard University; Ph.D., Yale University Research Interests: Dr. Letsou’s laboratory investigates the molecular mechanisms underlying dorsal closure during embryonic development, focusing on evolutionarily conserved pathways like JNK and Dpp signaling. She also develops Drosophila models for Adrenoleukodystrophy (ALD), a fatal neurodegenerative disorder caused by VLCFA accumulation, aiming to elucidate disease etiology and identify therapeutic targets. Publication Trends: Her research integrates genetic, biochemical, and pharmacological approaches in Drosophila , emphasizing conserved mechanisms relevant to human health. Key themes include signal transduction pathways, epithelial morphogenesis, lipid metabolism, and neurodegeneration. Lab Activities: Dr. Letsou’s lab employs double mutant studies to explore gene redundancy in VLCFA metabolism, characterizes dorsal closure dynamics, and screens for neuroprotective drugs using Drosophila models.

Koushik Royمشاهده پروفایل

استادیار

• Immunological Memory
• Protein Design
• Vaccine Development
• +۶ مورد دیگر

Koushik Roy is an Assistant Professor of Microbiology & Immunology at the University of Utah School of Medicine , specializing in B cell fate decisions, immunological memory, and vaccine development. His research bridges molecular biology, systems immunology, and chemical biology to address fundamental and translational challenges in infectious diseases and cancer. Education: M.S., Jadavpur University Ph.D., CSIR-Indian Institute of Chemical Biology Postdoctoral Research, University of California, Los Angeles Research Focus: Dr. Roy's lab investigates the molecular mechanisms governing B cell differentiation into plasma cells and memory B cells, particularly how pathogens disrupt these processes. His work combines systems biology (omics, microscopy, mathematical modeling) and chemical biology (peptide design) to develop therapeutic strategies for B cell lymphomas and vaccines against infectious diseases. Key Projects: 1. NFkB signaling in B cell fate: Deciphering how NFkB dynamics regulate proliferation-differentiation transitions. 2. Quantitative B cell responses: Modeling immune dysregulation in infectious diseases. 3. Peptide-based immunomodulators: Engineering synthetic peptides for vaccine enhancement and cancer therapy. Scientific Recognition: F1000 Faculty Recommended - New Finding (2019) F1000 Faculty Recommended - Interesting Hypothesis (2013, 2016) Laboratory Philosophy: Emphasizes rational thinking, open feedback, self-criticism, diversity, and mental health awareness in scientific mentorship.

Jared Rutterمشاهده پروفایل

استاد

• Metabolism
• Mitochondrial Biology
• Cell Signaling
• +۶ مورد دیگر

Jared Rutter is Distinguished Professor of Biochemistry and an Adjunct Professor of Nutrition and Integrative Physiology at the University of Utah, where he is also an HHMI Investigator. His laboratory spans the Biological Chemistry and Molecular Biology PhD programs, using yeast, Drosophila, mammalian cells, and mice to dissect metabolism and mitochondrial biology. Education B.S., Brigham Young University Ph.D., University of Texas Southwestern Medical Center Research Focus The Rutter group is driven by a central question: how does metabolism control cell fate? They pursue three interlocking themes: MIDAS platform — high-throughput mass spectrometry coupled to equilibrium dialysis for systematic discovery of allosteric metabolite-protein interactions. Mitochondrial Biology — multidisciplinary genetics, imaging, and biochemical approaches to reveal evolutionarily conserved proteins governing mitochondrial function and human disease. Mitochondrial Pyruvate Carrier (MPC) — a complex they discovered in 2012 that dictates pyruvate fate, thereby steering energy production, stemness, and cancer cell proliferation. Publication Trends Across >50 high-impact papers from 2009-2025, Rutter’s work defines how metabolites serve as signaling molecules, how mitochondrial transporters gate metabolic flux, and how rewiring these pathways can treat cancer, heart failure, and inherited metabolic disorders. His most recent studies integrate metabolomics with structural biology to map allosteric networks and exploit them therapeutically. Scientific Awards While specific honors are not enumerated in the source text, Rutter’s designation as an HHMI Investigator and Distinguished Professor signals sustained national and international recognition. Training & Collaboration The Rutter laboratory welcomes rotation students and fosters cross-disciplinary collaborations across the University of Utah Health Sciences campus and beyond. Prospective trainees are encouraged to contact Dr. Rutter directly or follow the lab website and Twitter @RutterLab .

Dana L. Vanlandinghamمشاهده پروفایل

استاد

• Arbovirology
• Vector-Borne Diseases
• Virus Transmission Dynamics
• +۵ مورد دیگر

Dana L. Vanlandingham is Professor of Arbovirology and Interim Associate Dean for Research and Graduate Programs at Kansas State University's College of Veterinary Medicine, Department of Diagnostic Medicine/Pathobiology. With a Ph.D. from Liverpool School of Tropical Medicine and M.S. and B.S. degrees from Colorado State University, she has established herself as a leading researcher in vector-borne diseases. Her research focuses on arbovirology, particularly the transmission dynamics of flaviviruses and alphaviruses including West Nile virus, Japanese encephalitis virus, Zika virus, and Cache Valley virus. Dr. Vanlandingham's work examines virus-vector-host interactions, vaccine development, and pathogenesis of mosquito-borne diseases. She has made significant contributions to understanding how environmental factors influence virus transmission and has developed novel approaches for virus detection and inactivation. Analysis of her recent publications reveals a strong emphasis on vaccine development for arboviruses, investigation of animal reservoirs for Japanese encephalitis, and assessment of SARS-CoV-2 transmission potential by arthropods. Her work spans basic virology, applied veterinary medicine, and public health implications of vector-borne diseases. Fellow of the Royal Entomological Society (F.R.E.S.) Dr. Vanlandingham leads research projects examining the role of animal reservoirs in arbovirus transmission cycles and develops novel vaccine platforms for emerging vector-borne pathogens. Her laboratory utilizes both in vitro and in vivo models to study virus-vector interactions and pathogenesis. She collaborates extensively with researchers across multiple institutions on projects related to emerging infectious diseases and biocontainment research. Her work has important implications for both veterinary and human public health, particularly in understanding the One Health aspects of vector-borne disease transmission and developing countermeasures against emerging arboviral threats.

• Human Anatomy
• Molecular Chaperones
• Heat Shock Proteins
• +۴ مورد دیگر

Francesco Cappello is a Full Professor in the Department of Biomedicine, Neuroscience and Advanced Diagnostics at the University of Palermo, Italy, where he also serves as Vice-Rector for Student Life. His office is located in the Human Anatomy and Histology Building, where he maintains regular office hours for students. Professor Cappello teaches across multiple departments including Medicine and Surgery, Biomedical Engineering, and Sciences of Motor and Sport Activities. Professor Cappello's research program centers on molecular chaperones, particularly Heat Shock Protein 60 (Hsp60), and their roles in various physiological and pathological conditions. He has developed the concept of the "muco-microbiotic layer" as a novel morphofunctional structure and investigates how probiotics and nanovesicles might target this layer in disease conditions. His work spans multiple systems including the digestive system, skeletal muscle, neuroendocrine system, and respiratory system, exploring Hsp60's potential as both a biomarker and therapeutic target. Analysis of Professor Cappello's recent publications reveals a comprehensive exploration of Hsp60 across multiple disease contexts. His 2025 publications demonstrate particular interest in the relationship between Hsp60 and skeletal muscle diseases, digestive system pathologies, and the neuroendocrine system. He is also pioneering connections between molecular chaperones and artificial intelligence applications in biomedical research, while investigating the therapeutic potential of probiotics like Lactobacillus fermentum LF31 in modulating inflammatory pathways and muscle atrophy. Professor Cappello has maintained consistent teaching responsibilities across multiple academic years, instructing Human Anatomy II in Medicine and Surgery programs, Elements of Anatomy in Biomedical Engineering specializations, and Human Morphology courses in Motor and Sport Sciences. His teaching spans both foundational anatomy and specialized applications across various health science disciplines, reflecting his broad expertise in anatomical sciences.

• Infectious Diseases
• Vector-borne Diseases
• Molecular Biology
• +۶ مورد دیگر

Erol Fikrig is the Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and Microbial Pathogenesis at Yale School of Medicine . He serves as Section Chief of Infectious Diseases and is affiliated with the Yale Institute for Global Health and the Fikrig Lab . Yale Combined Program in the Biological and Biomedical Sciences Yale-UPR Integrated HIV Basic and Clinical Sciences Initiative Education: MD, Cornell University (1985) Residency, Vanderbilt University Hospital (1988) Fellowship, Yale University School of Medicine (1991) Research Interests Dr. Fikrig investigates molecular interactions between pathogens (Borrelia burgdorferi, Flaviviruses, Plasmodium) and their vectors (ticks, mosquitoes), focusing on: Mechanisms of immunity evasion in vector-borne diseases mRNA vaccine development targeting vector salivary proteins Pathogen transmission dynamics at the vector-host interface Immunomodulation by arthropod saliva Tick and mosquito genetic targets for disease prevention Host-pathogen-vector triangular interactions Publication Trends Recent work emphasizes: mRNA vaccines for tick-borne diseases (Lyme, babesiosis) Salivary biomarkers of Plasmodium exposure Tick protein disulfide isomerases in Borrelia colonization AgTRIO and mosGILT proteins in mosquito biology Immune checkpoint targeting by mosquito factors Epidemiological modeling of vector-pathogen systems Scientific Honors National Academy of Medicine (2024) NIH Merit Award Howard Hughes Medical Institute Investigator Pew Scholar in Biomedical Sciences Infectious Disease Society of America Vaccine Development Award Collaborative Networks Key collaborations include: Yale School of Public Health researchers Johns Hopkins Malaria Research Group National Institutes of Health Tick-Borne Disease Working Group European Tick Vaccine Consortium Center for Infection and Immunity Yale-UPR HIV Research Initiative