جست‌وجوی استاد و پژوهشگر

Sabrina Leslieمشاهده پروفایل

دانشیار

• Single-molecule biophysics
• Biotechnology
• Fluorescence microscopy
• +۵ مورد دیگر

Sabrina Leslie is an Associate Professor at the University of British Columbia (UBC), affiliated with the Michael Smith Laboratories, the Department of Physics & Astronomy, and the School of Biomedical Engineering. Her research focuses on single-molecule biophysics and imaging technologies, particularly the CLiC platform, to advance genetic medicines and vaccine development. She holds a BSc from UBC and a PhD from UC Berkeley, with postdoctoral training at Harvard University. Dr. Leslie’s work bridges physics, biology, and engineering, with contributions to nucleic acid interactions, nanoparticle dynamics, and therapeutic oligonucleotides. She has received numerous awards, including the Killam Accelerator Fellowship and membership in the Royal Society of Canada. Her lab actively collaborates with industry and academia, emphasizing commercialization through her spin-off company, ScopeSys. Education: BSc (Physics & Mathematics, UBC, 2002), PhD (Optical & Atomic Physics, UC Berkeley, 2008) Affiliations: Michael Smith Laboratories, Department of Physics & Astronomy, School of Biomedical Engineering Research Themes: Single-molecule imaging, lipid nanoparticles, DNA dynamics, therapeutic delivery systems Awards: Killam Fellowship, Young Investigator Award, NSERC Accelerator Award Grants: CFI Innovation Fund, NSERC Accelerator Grant Her lab develops cutting-edge imaging tools like the CLiC platform to study biomolecules and nanomaterials in real-time, enabling advancements in diagnostics and therapeutics. Collaborations span academia and industry, with a focus on translating discoveries into clinical applications.

James W. Schneiderمشاهده پروفایل

استاد

• Biomaterials
• Medical Devices
• Bionanotechnology
• +۶ مورد دیگر

Dr. James W. Schneider is a Professor of Chemical Engineering and Courtesy Faculty in Biomedical Engineering at Carnegie Mellon University. He holds a B.S. in Chemical Engineering from the University of Wisconsin (1992) and a Ph.D. from the University of Minnesota (1998), followed by postdoctoral research at the Naval Research Laboratory. His research focuses on self-assembly principles in biomaterials, particularly amphiphilic molecules for applications in DNA/RNA detection, medical device development, and biomanufacturing process monitoring. Key contributions include micelle-based DNA electrophoresis and PNA amphiphile technologies for nucleic acid quantitation. Research interests span bionanotechnology, medical devices, and biomaterials with emphasis on programmable materials for diagnostic tools. Notable awards include the NSF CAREER Award (2001) and Beckman Young Investigator Award (2002), and he is a Fellow of the American Institute for Medical and Biological Engineering (2014). Current work includes collaborations with the Center for Nucleic Acids Science and Technology (CNAST) on PNA-based viral contaminant detection systems and surfactant studies in nonpolar liquids. His lab develops bioinspired materials for applications in biomanufacturing, drug delivery, and rapid diagnostic technologies.

Ana Casañalمشاهده پروفایل

پژوهشگر

• Structural Biology
• Molecular Biology
• Biochemistry
• +۴ مورد دیگر

Ana Casañal is a Group Leader at the Structural Biology Center of Human Technopole in Milan, Italy (since 2021). Previously, she was a postdoctoral researcher and EMBO Long Term Fellow at the MRC Laboratory of Molecular Biology in Cambridge, UK (2014-2020). Her research focuses on structural biology of mRNA processing machinery and plant biochemical pathways, utilizing cryo-EM and biochemical approaches. Education: PhD in Biotechnology, University of Málaga, Spain (2014), with highest honors. Thesis: "The Fra allergens and their role in the control of flavonoid biosynthesis in strawberry plants" . Supervisors: Prof. V. Valpuesta and Dr. J.A. Márquez. Master in Advanced Biotechnology, University of Málaga-International University of Andalusia (2010). Bachelor's Degree in Biochemistry, University of Málaga (2008). Research Interests: Combines structural biology with molecular genetics to study RNA processing complexes and plant metabolic regulators. Specializes in cryo-EM to visualize molecular machines involved in mRNA maturation and plant defense mechanisms. Explores transcription factor networks controlling secondary metabolites in strawberries. Recognition: Received the FEBS Anniversary Prize (2019) for exceptional contributions to biochemistry and molecular biology. Recipient of the Brenner Postdoc Prize (2018) for outstanding research at the MRC-LMB. Holds multiple fellowships including EMBO-Marie Curie and MRC awards. Teaching: Guest lecturer in Structural Biology for the Biotechnology Master's Program at the University of Málaga since 2012. Regularly teaches courses on cryo-EM, protein structure analysis, and model building. Labs/Teams: Leads the Casañal Group at Human Technopole, focusing on integrating structural and functional studies of RNA-processing complexes in plants and eukaryotes.

Ivan Marazziمشاهده پروفایل

دانشیار

• Epigenetics
• Transcriptional Regulation
• NF-kappaB Signaling
• +۲ مورد دیگر

Ivan Marazzi is Associate Professor of Biological Chemistry at UC Irvine School of Medicine, leading the Center for Epigenetics & Metabolism. Research explores transcriptional regulation dynamics, NF-kappaB signaling, and chromatin organization in inflammation and host-virus interactions. Recent investigations focus on circadian control of immunity, DNA damage responses, and therapeutic targeting of inflammatory pathways. The lab employs molecular biology and genomics approaches to study transcriptional mechanisms in viral infections, cancer, and immune disorders.

• Genomics
• Statistical Genetics
• Polygenic Risk Scores
• +۷ مورد دیگر

Bogdan Pasaniuc is a Professor in the Departments of Pathology and Laboratory Medicine, Human Genetics, and Computational Medicine at the University of California, Los Angeles (UCLA). His academic career spans multiple disciplines within genomics and computational biology, with a focus on advancing precision medicine through genetic and genomic research. He holds a BSc in Computer Science from A.I. Cuza University of Iasi (2003) and a PhD in Computer Science and Bioinformatics from the University of Connecticut (2008). His postdoctoral training included positions at the Broad Institute of Harvard and MIT (2012), Harvard School of Public Health (2012), and ICSI at UC Berkeley (2010), where he specialized in statistical genetics and computational biology. His research interests encompass statistical genetics, polygenic risk scoring, and the application of computational methods to understand genetic architecture across diverse populations. He focuses on translational research in precision medicine, including the development of tools for polygenic risk assessment and their implications in healthcare disparities. Key areas include the genetic underpinnings of complex diseases such as cancer, neuropsychiatric disorders, and metabolic conditions, alongside the integration of genomic data with electronic health records (EHR) for clinical insights. Notable contributions include leadership in the UCLA ATLAS Community Health Initiative and the PRIMED Consortium, which aim to improve polygenic risk assessment in underrepresented groups. His work also extends to the All of Us Research Program, leveraging large-scale genomic and health data to enhance disease understanding and precision medicine applications. He collaborates across institutions and leads research teams focused on computational methods for admixture mapping, genetic epidemiology, and multi-omics integration. His projects often emphasize reducing disparities in genomic research and ensuring equitable access to precision health solutions.

• homologous recombination
• DNA repair
• genome instability
• +۵ مورد دیگر

Yi Yin is an Assistant Professor in the Department of Human Genetics at the University of California, Los Angeles (UCLA) School of Medicine. Her research focuses on understanding homologous recombination (HR), a major pathway for repairing double-strand breaks in DNA, which has critical implications in cancer biology, development, and genome stability. Dr. Yin received her PhD and MS in Genetics and Genomics and Statistical Science, respectively, from Duke University in 2015. Her educational background has equipped her with a strong foundation in both biological mechanisms and quantitative analysis. Her research interests center on building a probabilistic understanding of homologous recombination through the development of high-throughput single-cell sequencing technologies. The central vision of her lab is to develop tools that can predict genome fragility, identify epigenetic contexts regulating DNA breakage, determine how DNA repair gene variants affect repair processes, and understand the consequences of HR from single cells to individuals. She has developed the sci-L3 suite of single-cell sequencing technologies, which enables linear amplification of single-cell genomes at scale (up to 1 million cells) and supports multi-omics applications including whole-genome sequencing, targeted sequencing, and DNA/RNA co-assays. Analysis of Dr. Yin's publication record reveals a consistent research trajectory focused on DNA repair mechanisms, particularly using yeast as a model organism to study homologous recombination. More recently, her work has expanded to include SARS-CoV-2 genomic epidemiology, demonstrating the versatility of her genomic technologies. Her publications show increasing impact, with several highly cited papers in top journals like Nature Biomedical Engineering, Molecular Cell, and Nature Biotechnology. Damon Runyon-Dale F. Frey Award for Breakthrough Scientists, Damon Runyon Cancer Research Foundation (2020-2022) Damon Runyon Fellowship Award, Damon Runyon Cancer Research Foundation (2016-2019) Dr. Yin serves as Principal Investigator on NIH R35GM142511 "Understanding spontaneous mitotic crossover by single-cell multi-omics" (2021-2026), which supports her development of a full-fledged HR mapping platform. Her lab is working to characterize genome, tissue, and evolutionary variation in mitotic HR rates and machinery, with broader interests in genome-wide characterization of HR partner choice, cell-type variation in DNA repair pathway usage, construction of dense linkage maps in non-model organisms, and discovery of new DNA repair genes in unculturable microbes. The Yin Lab @ UCLA continues to push the boundaries of genomic technology development and its application to fundamental biological questions.

Richard Kimberمشاهده پروفایل

پژوهشگر ارشد

• Environmental Geochemistry
• Nanotechnology
• Bioremediation
• +۳ مورد دیگر

Richard Kimber is a Research Fellow at the University of Manchester, holding the Dr Dame Kathleen Ollerenshaw Fellowship in Earth and Environmental Sciences. Previously, he served as a Junior Group Leader at the University of Vienna (2020–2023). His research focuses on two core areas: 1) the environmental fate of nucleic acids, examining how geochemistry influences DNA/RNA stability in contexts like ancient DNA preservation and wastewater epidemiology; and 2) microbial valorisation of metals, developing sustainable methods to convert waste metals into catalytic nanomaterials. His work aligns with UN Sustainable Development Goals related to sustainable production and responsible consumption (SDG 12) and climate action (SDG 13). Kimber earned his PhD in 2013 from the University of Manchester, focusing on the biogeochemical behavior of plutonium and americium in contaminated soils under supervisors Prof. J. Lloyd and Prof. F. Livens. Research Themes: Environmental nucleic acid stability and preservation mechanisms Microbial synthesis of biogenic nanoparticles for industrial applications Metal biorecovery from waste streams using microbial processes Geochemical controls on ancient DNA recovery in sediments Recent Article Trends: Recent work emphasizes nanoparticle synthesis optimization (e.g., Pd and Cu nanoparticles), mercury isotope fractionation studies, and biomolecule-mineral interactions in both terrestrial and extraterrestrial contexts. Over 20 peer-reviewed articles highlight his contributions to environmental geochemistry and sustainable nanotechnology.

Akhil Vaidyaمشاهده پروفایل

استاد

• Molecular Parasitology
• Antimalarial Drug Development
• Mitochondrial Biology
• +۲ مورد دیگر

Akhil Vaidya, PhD, is a Professor in the Department of Microbiology & Immunology at Drexel University College of Medicine, where he also serves as Director of the Center for Molecular Parasitology. He obtained his PhD from the University of Bombay in 1972. His research focuses on understanding the molecular functioning of malaria parasites to develop new antimalarial drugs, with particular emphasis on mitochondrial biology and parasite metabolism. His laboratory investigates essential mitochondrial processes in Plasmodium parasites including electron transport chain function, ATP synthase assembly, and pyrimidine biosynthesis pathways. These studies have led to discoveries of novel drug targets and mechanisms of existing antimalarials like atovaquone/proguanil (Malarone). Dr. Vaidya collaborates internationally on drug discovery projects with Medicines for Malaria Venture, including development of pyrazoleamide compounds that disrupt parasite sodium homeostasis. Research publications demonstrate consistent focus on molecular parasitology, mitochondrial function in apicomplexans, antimalarial drug mechanisms, and parasite metabolism. Recent work explores mitochondrial ribosomal proteins, metabolic roles of endosymbiotic organelles, and transcriptional regulation in Plasmodium. Honors & Awards: Provost Award for Outstanding Scholarly Productivity - Career (2024) Award for Excellence in Basic Science Mentoring (2023) He leads a research team including staff scientists Joanne Morrisey, Michael Mather, and Sudipta Das, and advises graduate students April Pershing, Ming Yang, Lindsay Pomykala, and Suyash Bhatnagar. His work is supported by grants from the NIH and Medicines for Malaria Venture.

Qi Luمشاهده پروفایل

دانشیار

• Nanoparticle-Membrane Interactions
• Biomedical Applications of Nanoparticles
• EEG Analysis of Music Tuning Effects
• +۴ مورد دیگر

Dr. Qi Lu is an Associate Professor in the Department of Physics within the Division of Physics, Engineering, Mathematics, and Computer Science at Delaware State University. He holds a Ph.D. in Physics from Clemson University (2006), an M.S. in Physics from Clemson University (2002), and a B.S. in Applied Physics from Shanghai Jiao Tong University (1998). His research focuses on nanoparticle interactions with lipid membranes, optical imaging applications in biomedicine, and the effects of music tuning on brainwaves via EEG analysis. He has co-authored over 15 publications in peer-reviewed journals and contributed to multimodal deep learning and quantum confinement materials design projects. Dr. Lu's expertise spans imaging optics, machine learning, and grant writing. He has secured significant funding including a $431,935 DoD grant (2023-2025) as Co-PI for neuro-pain research and a $799,058 NSF grant (2021-2024) as Co-lead for soft matter and quantum design research. His work bridges nanotechnology with biological systems, particularly exploring how nanoparticles influence membrane structures and potential medical applications. Grants: DoD: Multimodal Deep-Learning for NeuroPain ($431,935, 2023-2025) NSF: SMaRT QD Materials Design ($799,058, 2021-2024) Labs/Teams: Collaborates with the Center of Excellence for Emerging Technologies and the Advanced Quantum Sensing Center at DSU.

Fanny Elahiمشاهده پروفایل

دانشیار

• Vascular Cognitive Impairment (VCID)
• Neurodegenerative Diseases
• Biomarker Discovery
• +۷ مورد دیگر

Fanny Elahi is an Associate Professor at the Icahn School of Medicine at Mount Sinai, specializing in vascular cognitive impairment (VCID), neurodegenerative diseases, and biomarker discovery. Her research focuses on neurovascular mechanisms, blood-brain barrier dysfunction, and the development of novel biomarkers using extracellular vesicles and proteomics. She has contributed to studies on Alzheimer’s disease, cerebral small vessel disease, and the impact of systemic factors like atherosclerosis on brain health. Education: Graduated from the Icahn School of Medicine at Mount Sinai (ISMMS) in 2011. Her work integrates clinical neurology with biotechnology, particularly in microfluidics and bioprinting for tissue vascularization. She participates in collaborative projects such as the Clearance of Interstitial Fluid (ISF) and CSF (CLIC) group within the Vascular Professional Interest Area (PIA). Research interests span neuroimmunology, endothelial dysfunction, and the role of inflammation in brain aging. Key themes include sex differences in neurovascular health, retinal imaging as a biomarker for intracranial pathology, and the proteomic analysis of cerebrospinal fluid. Her recent studies highlight the therapeutic potential of targeting complement proteins and the clinical implications of plasma biomarkers like placental growth factor. Publications emphasize longitudinal cohort analyses (e.g., SPRINT-MIND trial follow-up), biomarker validation, and translational approaches in neurodegenerative diseases. She collaborates internationally on CADASIL consortium studies, focusing on early-phase VCID and genetic cerebrovascular diseases.

Sarah Signorمشاهده پروفایل

استادیار

• Evolutionary Biology
• Genetics
• Developmental Biology
• +۳ مورد دیگر

Sarah Signor is an Assistant Professor in the Department of Biological Sciences at North Dakota State University (NDSU). Her primary research focuses on evolutionary biology, particularly using Drosophila as a model organism to study gene expression evolution, transposable element dynamics, and organismal adaptation to environmental changes. She leads a lab investigating how gene expression evolves within networks, responds to heterogeneous environments, and adapts to human-modified landscapes. Her research spans topics such as transposable element activity in bees, ethanol tolerance in Drosophila , and the evolutionary mechanisms underlying phenotypic plasticity. Key contributions include studies on transposable element invasions, piRNA-mediated defense systems, and genomic analyses of Drosophila species. Signor’s publications reflect a strong focus on molecular and evolutionary genetics, including work on horizontal transfers of transposable elements, sex-biased gene expression, and the genetic basis of adaptation. Her lab emphasizes interdisciplinary approaches, integrating genomic, ecological, and developmental methodologies. While no formal student advisees are listed, her research team actively collaborates on projects involving evolutionary genomics and environmental biology. Grants and funding details are not explicitly mentioned in the provided texts, but her lab’s work suggests sustained research activity in these areas.

Julie A. Saugstadمشاهده پروفایل

پژوهشگر

• Cell/Molecular Neurobiology
• Signal Transduction
• MicroRNA
• +۳ مورد دیگر

Dr. Julie A. Saugstad is a researcher specializing in Cell/Molecular Neurobiology, focusing on Alzheimer's Disease, Neuroprotection, and the role of MicroRNA and Extracellular Vesicles in neurological processes. She holds a Ph.D. from the University of Oklahoma Health Sciences Center (1991) and completed her postdoctoral fellowship at the Vollum Institute (1991-1996). Dr. Saugstad is actively involved in collaborative research, contributing to advancements in understanding neurodegenerative diseases and extracellular vesicle biology. Education: Ph.D., 1991, University of Oklahoma Health Sciences Center Postdoctoral Fellow, Vollum Institute, 1991-1996 Research Interests: Dr. Saugstad’s work centers on Cell/Molecular Neurobiology , with a focus on Signal Transduction , MicroRNA , and Extracellular Vesicles . Her research explores their roles in Alzheimer’s Disease and strategies for Neuroprotection . Her studies often address sex-specific differences in neurodegenerative processes and the application of biomarkers in clinical diagnostics. Publications Overview: Dr. Saugstad’s recent work includes studies on Alzheimer’s biomarkers, the impact of prenatal THC exposure on neurodevelopment, and the standardization of extracellular vesicle research methodologies. Her contributions span interdisciplinary collaborations, emphasizing reproducibility and translational applications. Awards & Honors: None explicitly mentioned in the provided information. Advising & Grants: While specific grants or student advisement details are not listed, her extensive co-authorship network suggests active participation in collaborative research projects, likely involving grant-funded initiatives. Labs & Collaborations: Engaged with the International Society for Extracellular Vesicles. Her work often involves interdisciplinary teams, as reflected in co-authorships with institutions such as Oregon Health & Science University and the University of Miami.

Indranil Mukhopadhyayمشاهده پروفایل

استاد

• Biostatistics
• Statistical Genetics
• Genomics
• +۳ مورد دیگر

Indranil Mukhopadhyay serves as a Professor in the Department of Statistics at the University of Nebraska-Lincoln, where he conducts cutting-edge research at the intersection of statistics, genomics, and public health. His work bridges theoretical statistical methodology with urgent real-world health challenges, particularly in infectious disease modeling and genomic data analysis. His primary research interests encompass biostatistical methodology development for multi-omics integration, epidemiological modeling of infectious diseases (notably HIV/AIDS and COVID-19), and statistical genetics for complex trait analysis. He has pioneered robust computational frameworks for handling high-dimensional biological data, with emphasis on isoform quantification, gene expression clustering, and genetic association studies in diverse populations. Analysis of his recent publications reveals a strong trajectory toward public health applications , where statistical models directly inform pandemic response strategies and disease control policies. His work consistently demonstrates innovation in adapting mathematical frameworks (e.g., critical community size theory) to contemporary health crises, while maintaining rigorous methodological foundations in sequential estimation and robust statistics. No scientific awards were documented in the provided materials. Information regarding student advising, research grants, or laboratory infrastructure was not available in the source text. His publication record suggests active collaboration with medical researchers, particularly in studies involving Indian population cohorts and rare genetic disorders. No details about specific research laboratories or collaborative teams were provided in the available documentation.

Christine Beuckمشاهده پروفایل

استادیار

• Nuclear Magnetic Resonance (NMR) Spectroscopy
• Protein Interactions
• Structural Biology
• +۳ مورد دیگر

Dr. Christine Beuck is an Assistant Professor at the University of Duisburg-Essen, affiliated with the Faculty of Biology and the Centre for Medical Biotechnology (ZMB). Her research focuses on structural and medicinal biochemistry, particularly using Nuclear Magnetic Resonance (NMR) spectroscopy to study protein interactions and supramolecular ligand binding. She is a key member of the Collaborative Research Center (CRC) 1093, investigating protein interactions with synthetic ligands and their biological implications. Education: She earned a Diploma in Chemistry from TU Dortmund (2001) and a Ph.D. in Chemistry from RWTH Aachen University (2005) under Prof. E. Weinhold. Postdoctoral training included work at The Scripps Research Institute (2005–2014) under Prof. J. R. Williamson, followed by a Japan exchange program at Tokyo University (2005) and a Lithuania exchange at the Institute of Biotechnology (2003). Research Interests: Her work combines NMR spectroscopy with biochemical techniques (e.g., fluorescence, ITC, BLI) to analyze protein-ligand interactions, protein structures, and dynamics. She pioneered side-chain-specific NMR experiments for lysine/arginine residues and employs advanced NMR methods like BEST-TROSY for large proteins. Applications span drug design, understanding disease-linked protein dysfunctions, and nanotechnology (e.g., gold nanoparticle characterization). Advising & Grants: While specific grants are not detailed, her CRC 1093 affiliation indicates collaborative funding. Her research contributes to developing supramolecular ligands to modulate biological interactions, with potential medical and biotechnological applications. Labs/Teams: She leads projects in the ZMB and collaborates with institutions worldwide, including The Scripps Research Institute and Tokyo University. Her lab integrates structural biology, medicinal chemistry, and nanotechnology to address complex biological questions.

Simon Moxonمشاهده پروفایل

دانشیار

• Bioinformatics
• Gene Regulation
• Next-Generation Sequencing
• +۳ مورد دیگر

Simon Moxon is an Associate Professor in Bioinformatics at the University of East Anglia (UEA), part of the School of Biological Sciences. His research focuses on applying next-generation sequencing (NGS) technologies to study biological problems, particularly small RNA bioinformatics and mechanisms of gene regulation at transcriptional and post-transcriptional levels. He has developed tools like miRCat2 and the UEA sRNA Workbench for miRNA detection and analysis. Notable collaborations include projects funded by the British Heart Foundation, NIH, and the Natural Environment Research Council, exploring topics such as chromatin landscapes, microRNA biogenesis, and epigenetic reprogramming. His work spans plant genomics, developmental biology, and molecular mechanisms in diseases like cancer. Recent publications highlight advancements in understanding miRNA regulation in plants and animals, epigenetic marks during zygotic reprogramming, and antimicrobial resistance in Bacillus species. Moxon actively mentors PhD students and contributes to editorial roles in journals like Frontiers in Molecular Biosciences.