جست‌وجوی استاد و پژوهشگر

Ben Montpetitمشاهده پروفایل

استادیار مدعو

• Molecular Biology
• Cell Biology
• RNA Biology
• +۳ مورد دیگر

Ben Montpetit is an Adjunct Assistant Professor in the Department of Viticulture & Enology at the University of California at Davis, College of Agricultural and Environmental Sciences. His research focuses on the molecular mechanisms of mRNA export through nuclear pore complexes (NPCs) and its implications in cellular stress responses and human diseases. Ph.D., University of British Columbia Research Interests Montpetit’s work investigates how NPCs regulate mRNA export at cellular, molecular, and atomic levels. His lab employs cell biology , biochemistry , structural biology , and single-molecule imaging in Saccharomyces cerevisiae to elucidate transport mechanisms. Future directions include expanding studies to mammalian systems to link mRNA export defects to diseases like cancer and neurodegenerative disorders. Publication Trends Montpetit's articles span RNA biology , nuclear transport , and protein-RNA interactions , with a focus on DEAD-box ATPases, nucleoporins, and stress-regulated export pathways. His work bridges basic cell biology and clinical relevance , particularly in disease mechanisms. Lab Members The Montpetit Lab collaborates with a multidisciplinary team of undergraduates, graduate students, postdocs, and staff, leveraging yeast and mammalian models to advance mechanistic understanding of RNA transport and processing. Contact Email: benmontpetit@ucdavis.edu Office: Department of Viticulture & Enology, UC Davis Phone: 530-752-9355

Eric Janمشاهده پروفایل

استاد

• Translational Control
• Virology
• Gene Expression Regulation
• +۵ مورد دیگر

Eric Jan is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia's Faculty of Medicine. His research focuses on translational control mechanisms during cellular stress and viral infections, with a particular emphasis on internal ribosome entry sites (IRES) and their role in hijacking host translation machinery. He holds prestigious awards including the Michael Smith Scholar, CIHR New Investigator, and Killam Excellence for Mentoring Education, reflecting his contributions to both research and mentorship. Dr. Jan's lab explores how viruses like Cricket Paralysis Virus (CrPV) and SARS-CoV-2 manipulate ribosomes, and how these insights can be applied to mRNA-lipid nanoparticle (LNP) therapeutic technologies. Education: BSc (Queen’s University, 1994), PhD (Northwestern University, 1999), Postdoctoral Fellowship (Stanford University, 1999-2005). Research Interests: Dr. Jan investigates the noncanonical translation mechanisms of viruses, particularly how IRES elements bypass host initiation factors to drive protein synthesis. His work bridges fundamental gene expression studies with applications in antiviral therapies, diabetes research (via ER stress and eIF2A), and mRNA-LNP delivery systems. Recent projects include mining virome data for novel RNA elements, engineering platelets for therapeutic uses, and developing extrahepatic mRNA delivery strategies. Publications: His recent work (2023-2025) spans virome mining for IRES elements, mRNA-LNP formulation optimization, ER stress in beta cells, and viral protease impacts on host pathways. Key journals include Nature Communications , PLoS Pathogens , and Science Advances . Scientific Awards: Michael Smith Scholar CIHR New Investigator Killam Excellence for Mentoring Education Students and Lab Members: Current lab members include postdoctoral fellows, PhD and MSc students, and technicians working on viral translation, mRNA-LNP applications, and stress granule dynamics. His mentees have secured NSERC fellowships and co-supervised roles. Labs and Collaborations: The Jan Lab collaborates extensively on mRNA-LNP projects (e.g., with Cullis, Kastrup) and viral pathogenesis studies. They employ biochemical, virological, and high-throughput sequencing approaches to dissect host-virus interactions and RNA translation mechanisms.

Sandra Rehanمشاهده پروفایل

استاد

• Ecology
• Evolutionary Biology
• Genomics
• +۵ مورد دیگر

Sandra Rehan is a Full Professor in the Department of Biology at York University, affiliated with the Centre for Bee Ecology, Evolution and Conservation. Her research focuses on social evolution and biodiversity in bees, integrating molecular phylogeny, comparative genomics, behavioral ecology, and pollinator health. She explores how environmental factors like land use and climate change impact bee communities and their ecological roles. Research Interests: Behavioral Ecology: Social plasticity in bees, cooperative behavior, and aggression dynamics. Conservation: Pollinator health, habitat requirements, and responses to urbanization. Genomics: Comparative genomics of social evolution, microbiome interactions, and transcriptomic responses to stress. Key Findings: Uncovered evolutionary origins of sociality in carpenter bees using molecular phylogeny. Documented climate and land use impacts on wild bee populations and their microbiomes. Developed genomic tools for studying social behavior and local adaptation in bees. Labs/Groups: The Rehan Lab and the Bee Ecology, Evolution and Conservation research group at York University.

Geoffrey Schiebingerمشاهده پروفایل

دانشیار

• Mathematics
• Optimal Transport
• Probability
• +۷ مورد دیگر

Geoffrey Schiebinger is an Associate Professor of Mathematics at the University of British Columbia. His work bridges theoretical mathematics and experimental biology, focusing on optimal transport theory applied to high-dimensional gene expression data. He leads a research group developing mathematical tools for analyzing single-cell RNA sequencing and spatial omics data. Education: PhD in Statistics, UC Berkeley (2016), advised by Benjamin Recht M.S. in Electrical Engineering, Stanford University (2011) B.S. in Mathematics (minor in Physics), Stanford University Research interests center on understanding cellular differentiation processes, such as how stem cells transform into specialized cell types. His group applies optimal transport theory to model transcriptional landscapes and lineage trajectories, with applications in immunology, developmental biology, and cancer research. Key projects include the Waddington-OT framework for trajectory inference and DNA-GPS spatial genomics methodology. Notable awards include the 2022 Michael Smith Health Research BC Scholar Award and 2021 Maud Menten Prize. His grants include top rankings in Canadian genomics funding (CIHR Project Grant 1st place, 2021) and support from the Chan Zuckerberg Initiative. Advising: Supervises postdocs (Matthieu Heitz, Andrew Warren) and graduate students (e.g., Cole Boyle). Alumni include faculty at Wake Forest and Chinese University of Hong Kong. Active hiring: Postdoctoral and graduate positions available in mathematical biology and statistical genomics. Labs/Teams: Leads the Schiebinger Lab at UBC, collaborating with Philippe Rigollet (MIT) on Human Cell Atlas projects. Active in developing open-source tools for single-cell analysis.

Panayiotis O. Vacratsisمشاهده پروفایل

دانشیار

• Signal Transduction
• Cellular Phosphorylation
• Kinases
• +۴ مورد دیگر

Dr. Panayiotis O. Vacratsis is an Associate Professor in the Department of Chemistry and Biochemistry at the University of Windsor, Faculty of Science. He holds a Ph.D. in Biochemistry from Michigan State University and leads a research laboratory focused on signal transduction, cellular phosphorylation, and the functional roles of kinases and phosphatases in health and disease. Current research projects include: hYVH1 : Investigating its role in cell survival, ribosome biogenesis, and cancer progression. MTMR2 : Studying phosphorylation-regulated mechanisms in Charcot-Marie-Tooth disease. His lab employs advanced proteomic techniques, including biological mass spectrometry, to elucidate molecular pathways critical to cellular processes such as endosomal dynamics, RNP interactions, and neuromuscular signaling. Collaborative work spans neurodegenerative disease models, aquatic biology, and redox regulation studies.

• Molecular Biology
• Developmental Biology
• Neuroscience
• +۳ مورد دیگر

Agata Becalska is a Lecturer in the Department of Biological Sciences at Simon Fraser University (SFU). Her research focuses on molecular mechanisms of membrane trafficking, F-BAR domain proteins, and mRNA localization in developmental contexts, particularly in Drosophila models. Notable contributions include studies on Nervous Wreck protein dynamics, Retromer complex roles in synaptic function, and APP trafficking in neurons. She teaches courses such as BISC 303 (Microbiology). Her work bridges cell biology and neuroscience, emphasizing protein-membrane interactions and developmental processes. Publications span molecular biology, cell biology, and developmental research, with a focus on cellular mechanisms underlying neural and developmental pathways.

Chérif F. Mattaمشاهده پروفایل

استاد

• Theoretical Chemistry
• Quantum Chemistry
• Computational Biochemistry
• +۵ مورد دیگر

Dr. Chérif F. Matta is a Professor of Chemistry & Physics at Mount Saint Vincent University (Canada), specializing in theoretical and computational chemistry. His research focuses on quantum biochemistry, electron localization-delocalization matrices (LDMs), and mitochondrial ATP synthase mechanisms. He holds multiple fellowships including FAAAS, FRSB, FInstP, and FRSC. Education: PhD in Chemistry (2002), McMaster University Habilitation à Diriger des Recherches (2009), Université de Lorraine Bachelor of Pharmaceutical Sciences (1987), Alexandria University Postdoctoral training under Nobel laureate John Polanyi and Russell Boyd Research Interests: Quantum chemical topology (QTAIM) Mitochondrial biophysics Diffuse interstellar bands (DIBs) Prebiotic chemistry Quantum crystallography Awards: Over 20 prestigious awards including the John Charles Polanyi Prize 2021 Fellow of the American Association for the Advancement of Science 2016 Lady Davis Visiting Professorship in Israel Professional Service: Tri-Council of Canada member (2018–2022) Chair of Chemical Institute of Canada's accreditation (2021–2024) Guest editor for multiple special journal issues Labs/Teams: Leads the theoretical biophysics and quantum chemistry research group, collaborating globally on mitochondrial function and astrochemical studies.

Holger H. Hoosمشاهده پروفایل

استاد

• Algorithmics
• Bioinformatics
• Computational Intelligence
• +۹ مورد دیگر

Holger H. Hoos is a Professor at the University of British Columbia's Computer Science Department, affiliated with the Institute for Computational Intelligence and Cognitive Systems (ICICS) and the Peter-Wall Institute for Advanced Studies. As of 2017, his primary affiliation shifted to Leiden University (Netherlands), though he remains connected to UBC. His research focuses on algorithmics, bioinformatics, computational intelligence, and computer music, with significant contributions to stochastic local search, empirical algorithmics, and SAT solving. Education: Ph.D. (Dr.rer.nat) in Computer Science from TU Darmstadt (1998), postdoctoral fellow at UBC. He has led the BETA Lab and SALIERI Project, exploring biomolecular structure prediction and music algorithms. Research interests span stochastic algorithms, RNA structure prediction, automated algorithm configuration, and interdisciplinary applications like flow cytometry analysis. His work bridges theoretical foundations with empirical methods, emphasizing practical problem-solving. Awards include the AAAI Fellowship, multiple best paper awards (GECCO 2020, IJCAI-JAIR 2010), and leadership roles in conferences like AAAI and LION. He has advised over 30 students, contributing to impactful projects in bioinformatics and AI. Labs/Teams: Founder of the BETA Lab (Bioinformatics, Theoretical and Empirical Algorithms), member of the Laboratory for Computational Intelligence (LCI), and collaborator on SALIERI (Computer Music).

David Schriemerمشاهده پروفایل

استاد

• Integrative Structural Biology
• Clinical Proteomics
• Proteomics Technology
• +۳ مورد دیگر

David Schriemer is a Professor at the University of Calgary's Cumming School of Medicine (Department of Biochemistry and Molecular Biology) and an Adjunct Professor in the Faculty of Science's Department of Chemistry. He holds roles as a Child Health & Wellness Researcher at the Owerko Centre and a Member of the Arnie Charbonneau Cancer Institute and Robson DNA Science Centre. His academic career includes positions as a Canada Research Chair and Senior Scholar of the Alberta Heritage Foundation for Medical Research. Education: B.S. Chemistry (University of Winnipeg, 1991), M.S. Chemistry (University of Manitoba, 1993), Ph.D. Chemistry (University of Alberta, 1997). Postdoctoral training in biochemistry preceded his faculty appointment in 2001. He co-founded INH Technologies Inc. and served as Research Director at MDS Proteomics Inc. Research focuses on integrative structural biology and clinical proteomics, emphasizing protein complex structures, proteome-wide disease markers, and advanced mass spectrometry technologies. Key projects include developing AI-driven computational models for mesoscale protein functions and translational efforts in clinical proteomics for neurological disorders and cancer immunotherapy targets. Awards include the Cochrane Distinguished Achievement Award (2011, 2009, 2003), Shultz Award (2017), and Peak Scholar distinction (2015). He directs the Structural Proteomics Laboratory and leads initiatives in precision oncology through the Terry Fox Research Institute. Current ventures include a scientific software development company and leadership roles at Nepetx LLC.

François-Xavier Campbell-Valoisمشاهده پروفایل

دانشیار

• Microbiology
• Biochemistry
• Protein-Protein Interactions
• +۴ مورد دیگر

Dr. François-Xavier Campbell-Valois is an Associate Professor in the Department of Chemistry and Biomolecular Sciences at the University of Ottawa, Faculty of Science. His research focuses on understanding host-microbe interactions, particularly the virulence mechanisms of Shigella flexneri , an enteropathogen that employs the Type Three Secretion Apparatus (T3SA) to infect human intestinal cells. His work investigates T3SA regulation, bacterial strategies to hijack host processes, and host-pathogen adaptive dynamics, aiming to identify novel therapeutic targets for infectious diseases. The Host-Microbe Interactions Laboratory led by Dr. Campbell-Valois employs advanced microscopy, genetic tools, and proteomic approaches to study bacterial effectors and host responses. Key projects include developing fluorescent reporters for live imaging, analyzing T3SA substrates, and exploring Shigella’s oxygen-dependent colonization strategies. His interdisciplinary research bridges microbiology, biochemistry, and cell biology, with applications in antimicrobial development and understanding infection pathogenesis. Education: PhD in Biochemistry (specific details unspecified) Research interests span protein-protein interactions, bacterial secretion systems, and host-pathogen co-evolution. His laboratory’s innovations include concise plasmid systems (pUdOs) for bacterial and mammalian cells, and anaerobic fluorescent reporters for Pseudomonas aeruginosa imaging. Ongoing work emphasizes translational research to translate mechanistic insights into clinical interventions for infectious diseases.

• Nanoparticle synthesis
• Plasmonic materials
• Polymer and colloid chemistry
• +۴ مورد دیگر

Vladimir Kitaev is a Professor in the Department of Chemistry and Biochemistry at Wilfrid Laurier University. His research focuses on applications of nanoparticles, materials with tunable optical and electronic properties, nanoparticle synthesis, and polymer/colloid chemistry. Education: MSc in Polymer Chemistry from Lomonosov Moscow State University, PhD in Materials Chemistry from the University of Toronto Research: Nanoscale chirality, size- and shape-selective nanoparticle synthesis, plasmonic metal nanoparticles, biosensing substrates, water remediation technologies Current Projects: Collaboration with Nicoya Inc. on plasmonic sensors and Imperial Oil on environmental remediation His work explores colloidal nanoscale building blocks (NBBs) with controlled properties for sensing and photonics applications, particularly silver decahedra, pentagonal rods, and gold nanostructures. Research spans from fundamental nanoparticle synthesis to applied projects in cancer therapy, chemical detection, and photonic crystal development. The selected publications (2016-2025) focus on plasmonic materials, nanoparticle self-assembly, and biomedical applications. Key themes include nanoparticle surface chemistry, optical property control, and advanced sensing techniques. The research group (CLAN) specializes in translating nanoscience discoveries into practical solutions.

• Neuropathology
• Bioinformatics
• Neuro-oncology
• +۷ مورد دیگر

Dr. Jason Karamchandani is an Associate Professor at McGill University in the Department of Pathology , with dual appointments as an Investigator at the Research Institute of the McGill University Health Centre (RI-MUHC) and at the Montreal Neurological Institute and Hospital . His research integrates neuropathology , bioinformatics , and neuro-oncology to identify diagnostic, prognostic, and predictive markers for brain tumors and neuromuscular diseases. Keywords : Neuropathology • Bioinformatics • Neuro-oncology • Surgical Pathology • Neuromuscular Pathology Dr. Karamchandani’s work spans genomic heterogeneity in pediatric high-grade gliomas , oncohistone mutations , and mechanisms in vacuolar myopathies . He leads studies on immune landscapes in gliomas and autoimmune muscle disorders , leveraging long noncoding RNAs and phosphatase pathways for cancer stem cell regulation. His recent publications highlight collaborations in neurogenetics (e.g., VPS13D mutations ), epigenetic regulation ( TERT hypermethylation ), and immune profiling in oncohistone-mutant gliomas . He contributes to biobanking initiatives and open science frameworks for neurodegenerative and neuromuscular diseases.

• Neuroscience
• Developmental Brain Circuitry
• Autism Spectrum Disorder
• +۴ مورد دیگر

Dr. Kurt Haas is a Professor in the Department of Cellular & Physiological Sciences and the School of Biomedical Engineering at the University of British Columbia. His research focuses on molecular and cellular mechanisms of early brain circuit formation, with a particular emphasis on autism spectrum disorder (ASD), schizophrenia, and epilepsy. He employs cutting-edge imaging technologies, including in vivo microscopy and high-throughput cell assays, to study neural development and dysfunction. Expertise: Neurodevelopmental disorders, synaptic plasticity, in vivo imaging techniques Key Projects: Development of gene delivery methods, analysis of PTEN mutations in ASD, and creation of curated databases like BrainPalmSeq Research interests include structural and functional plasticity in the developing brain, dysfunctional neural networks, and the application of novel microscopy techniques. His lab integrates electrophysiology, molecular biology, and computational modeling to understand how genetic mutations impact neuronal development and connectivity. Recent work highlights contributions to imaging technologies (e.g., ultrafast two-photon microscopy) and functional analysis of disease-associated genes using yeast models. His studies on PTEN mutations reveal molecular mechanisms underlying protein dysfunction in autism and cancer. Dr. Haas collaborates with interdisciplinary teams to advance translational research, bridging basic neuroscience with clinical applications in neurodevelopmental disorders.

Laura Kuhlmannمشاهده پروفایل

پژوهشگر ارشد

• Breast Cancer Research
• MMP Enzymology
• Transcriptional Regulation
• +۳ مورد دیگر

Laura Kuhlmann is a Research Fellow at the University of British Columbia's Faculty of Dentistry, Department of Oral Biological and Medical Sciences, affiliated with the Centre for Blood Research. Her research focuses on uncovering novel roles and interaction partners of MMP12 in breast cancer, including its nuclear localization and transcriptional regulatory functions. She employs advanced techniques like RNA-SEQ, CHiP-SEQ, and TAILS to identify genes/proteins regulated by MMP12. Education includes a PhD in Cancer Biology (2010–2014) from DKFZ Heidelberg and University of Heidelberg, and a B.Sc. in Biochemistry from University of Bucharest (2003–2007). She completed postdoctoral training at UBC (2015–present) under Prof. Christopher M. Overall, and earlier work at DKFZ Heidelberg on pancreatic cancer biomarkers. Her conference presentations highlight expertise in toxicology and cellular stress responses, particularly involving heavy metals and mycotoxins. Key studies include manganese's effects on heat shock proteins and ochratoxin A's apoptotic mechanisms in HepG2 cells. No scientific awards or grants are explicitly listed. Advising roles or lab leadership details are absent, though she contributes to the Overall Lab's research infrastructure.

Patricia Lakin-Thomasمشاهده پروفایل

استاد

• Chronobiology
• Cell and Molecular Biology
• Circadian Rhythms
• +۳ مورد دیگر

Dr. Patricia Lakin-Thomas is a Full Professor in the Department of Biology at York University, Faculty of Science. Her research focuses on circadian rhythms in the fungus Neurospora crassa, investigating how organisms maintain daily biological clocks. She studies the molecular mechanisms of circadian oscillators, particularly the FRQ-Less Oscillator (FLO), which operates independently of known clock genes like FRQ and WC-1/2. Her lab uses Neurospora's spore-formation rhythms as a model to uncover universal principles of rhythmicity. Research Interests: Chronobiology, circadian rhythms, molecular genetics of Neurospora, biochemical oscillators, and the intersection of metabolism and circadian clocks. Publications highlight her work on the TOR pathway's role in circadian rhythms, genetic mutations affecting FLO, and cross-disciplinary studies linking metabolism to timing mechanisms. Her team includes over 30 graduate and undergraduate researchers trained in molecular biology and chronobiology. Led a lab with extensive student involvement (listed in full description), emphasizing hands-on training in fungal genetics and biochemistry. Collaborates internationally to advance understanding of fundamental biological timing mechanisms.