Jason Karamchandani

Dr. Jason Karamchandani is an Associate Professor at McGill University in the Department of Pathology, with dual appointments as an Investigator at the Research Institute of the McGill University Health Centre (RI-MUHC) and at the Montreal Neurological Institute and Hospital. His research integrates neuropathology, bioinformatics, and neuro-oncology to identify diagnostic, prognostic, and predictive markers for brain tumors and neuromuscular diseases.

• Keywords: Neuropathology • Bioinformatics • Neuro-oncology • Surgical Pathology • Neuromuscular Pathology

Dr. Karamchandani’s work spans genomic heterogeneity in pediatric high-grade gliomas, oncohistone mutations, and mechanisms in vacuolar myopathies. He leads studies on immune landscapes in gliomas and autoimmune muscle disorders, leveraging long noncoding RNAs and phosphatase pathways for cancer stem cell regulation.

His recent publications highlight collaborations in neurogenetics (e.g., VPS13D mutations), epigenetic regulation (TERT hypermethylation), and immune profiling in oncohistone-mutant gliomas. He contributes to biobanking initiatives and open science frameworks for neurodegenerative and neuromuscular diseases.