جست‌وجوی استاد و پژوهشگر

• Bioinformatics
• Proteomics
• Genomics
• +۴ مورد دیگر

Rolf Apweiler serves as Director of the European Bioinformatics Institute (EMBL-EBI), part of the European Molecular Biology Laboratory, a position he has held since 2015. Previously, he was Associate Director (2012-2015) and led multiple critical protein resources including UniProt and InterPro. His leadership extends to directing Open Targets since 2018 and spearheading EMBL-EBI's contribution to the European COVID-19 Data Platform. Apweiler's research spans Bioinformatics, Proteomics, and Genomics , with significant contributions to protein annotation methods, proteomics data standards, and major biological databases. His work enables comprehensive analysis of proteome sets across entire organisms and has established foundational resources for the global scientific community. His publication portfolio demonstrates consistent leadership in developing critical bioinformatics infrastructure, with major contributions including UniProt, PRIDE, IntAct, and InterPro. These resources form the backbone of modern proteomics research and have been widely adopted across the life sciences. HUPO Distinguished Achievement Award in Proteomics (2004) EMBO Member (2011) ISCB Fellow (2015) President of Human Proteomics Organisation (2007-2008) As Director of EMBL-EBI, Apweiler oversees one of the world's leading bioinformatics institutions, managing extensive research programs, international collaborations, and major data infrastructure projects. His leadership in Open Targets demonstrates significant engagement with translational research connecting basic science to drug discovery. Apweiler's teams maintain several critical global resources including PRIDE (proteomics identifications), IntAct (molecular interactions), and UniProt (protein knowledgebase), forming an integrated ecosystem for biological data analysis.

• Plant Biotechnology
• Fleshy Fruit Development
• Fruit Ripening
• +۵ مورد دیگر

Mondher Bouzayen is a Full Professor (Classe Exceptionnelle) at the University of Toulouse's Institut National Polytechnique, specializing in plant biotechnology with a focus on fleshy fruit development. His research spans hormone signaling, fruit genomics, and transcriptional regulation in tomato and other climacteric fruits. His research interests center on deciphering molecular mechanisms underlying fruit ripening, set, and development. Key areas include ethylene and auxin signaling pathways, chromoplast differentiation, and genomic approaches to understanding fruit traits. His work bridges fundamental plant biology with agricultural applications, particularly in improving sensory and nutritional qualities of fruits. Analysis of his publications reveals consistent focus on tomato as a model system, with significant contributions to genome sequencing, hormone response factors, and metabolic regulation during ripening. His work demonstrates strong interdisciplinary integration of genomics, proteomics, and molecular genetics. Novela Award of the City of Toulouse (2013) for tomato genome sequencing Officier des Palmes Académiques (2011) - French national distinction Guangbiao Professeur Chair at Zhejiang University (2010) With 93 peer-reviewed publications (h-index: 35, g-index: 75, 4367 citations), his research has been published in top journals including Nature, PNAS, The Plant Cell, and Plant Physiology. His work on the tomato genome sequence represents a landmark contribution to plant science, providing essential resources for Solanaceae research worldwide.

Martin Seamusمشاهده پروفایل

استاد

• Immunology
• Cell Death
• Inflammation
• +۷ مورد دیگر

Seamus Martin is the Smurfit Professor of Genetics at Trinity College Dublin, Ireland, leading the Smurfit Institute of Genetics. His research focuses on programmed cell death, inflammation, and cancer links. He holds a PhD from the National University of Ireland and completed postdoctoral training at University College London and the La Jolla Institute for Immunology. He has been recognized with prestigious awards including the ERC Advanced Grant (2021), Boyle Medal (2014), and election to EMBO (2009) and the Royal Irish Academy (2006). He co-authored 'Essential Immunology' textbooks and serves as Editor-in-Chief of The FEBS Journal. His lab has produced >40,000 citations (Clarivate) and graduated over 20 PhD students. Education: PhD, National University of Ireland, 1990 Postdoctoral Fellowships at UCL (1990–1993) and La Jolla Institute (1993–1996) Research Interests: Apoptosis mechanisms and inflammation IL-1 family cytokine activation ER stress and cell death pathways Awards: ERC Advanced Grant (2021) RDS-Irish Times Boyle Medal (2014) EMBO Membership (2009) Lab Contributions: Key discoveries include annexin V labeling for apoptosis detection Unraveled caspase activation cascades Discovered IL-36/IL-37 cytokine activation mechanisms

Peter O'Hareمشاهده پروفایل

استاد

• HSV molecular biology
• Virus-host interactions
• Herpesvirus life cycle
• +۳ مورد دیگر

Professor Peter O'Hare holds the Chair in Virology at the Department of Medicine, Faculty of Medicine, Imperial College London . His research focuses on HSV molecular biology , virus-host interactions , and herpesvirus life cycle . He has led significant studies on herpes simplex virus (HSV) entry mechanisms, innate immune evasion, and transcriptional regulation. Education: Ph.D., National Institute for Medical Research, London (United Kingdom); B.Sc. Microbiology, University of Sheffield (United Kingdom). Research Interests: Professor O'Hare's lab investigates fundamental virus-host interactions during herpesvirus infection. Key areas include early genome entry, nuclear transport, and the interplay between viral proteins and host transcription machinery/innate immune responses. Techniques employed include molecular biology, click-chemistry, and single-cell/molecule analyses. Recent Work Trends: His articles emphasize HSV pathogenesis, viral protein functions (e.g., ICP22, VP1-2), and host cell modifications like emerin delocalization. Research spans transcriptional regulation (CREB-H/CREB4 factors), ER retention mechanisms, and ubiquitin/proteasome pathways. Awards: Academia Europaea Membership (2008) Scientific Advisory Committee roles (International Herpesvirus Workshop) Damon Runyon Fellowship (1983–1985) Advising & Grants: Supervised PhD students Hanan Moshrif and Kerina Naran. Active in boards for Marie Curie Cancer Care and National Cancer Research Institute. Secured funding for virology and translational research initiatives. Labs/Teams: Leads the Section of Virology at Imperial College London, collaborating on projects like HSV nuclear transport and innate immune evasion.

Jan Maarten van Dijlمشاهده پروفایل

استاد

• Medical Microbiology
• Bacterial Gene Expression
• Protein Secretion
• +۴ مورد دیگر

Prof. Jan Maarten van Dijl is a Professor of Medical Microbiology at the Faculty of Medical Sciences, University of Groningen (UMCG). His research focuses on bacterial gene expression, protein secretion, and host-pathogen interactions, with a particular emphasis on Staphylococcus aureus and Bacillus subtilis. He leads a lab investigating antimicrobial strategies, bacterial pathogenesis, and molecular imaging of infections. Prof. van Dijl has over 347 publications and holds editorial roles in journals such as Microbiology and BMC Microbiology. He is also a Visiting Professor at Kobe University, Japan, and co-founded Sabiad B.V., a startup developing rapid bacterial detection methods. His work contributes to UN Sustainable Development Goals related to health and well-being. Additional roles: Associate Editor of Microbiology (1998–2006), Coordinator of European research programs, Board member of BACELL and EFBA. Key achievements: 2018 fellowship for infection imaging research, 63 supervised works, and over 300 peer-reviewed articles. Research interests span bacterial protein localization, infection imaging (e.g., vancomycin-based PET tracers), and antimicrobial development. Recent work includes light-activated penicillin for spatial infection control and synthetic microarrays for sero-diagnosis. His lab collaborates globally, addressing challenges in antibiotic resistance and diagnostic innovation. Grants & Awards: 2018 DEtection and MOnitoring fellowship, Sabiad B.V. equity (non-majority), and multiple patents. Labs/Teams: Part of Microbes in Health and Disease (MHD) and Translational Immunology Groningen (TRIGR) groups. Active in recombinant protein production and imaging technology development.

V. van den Boomمشاهده پروفایل

پژوهشگر

• Hematology
• Oncology
• Epigenetics
• +۳ مورد دیگر

Dr. V. van den Boom is a researcher affiliated with the Faculty of Medical Sciences at the University of Groningen. Their work focuses on hematological malignancies, particularly leukemia, and the epigenetic regulation of gene expression in stem cells. Key research areas include understanding the molecular mechanisms underlying leukemogenesis and the role of epigenetic modifiers in cancer progression. Dr. van den Boom has contributed to studies on dietary methionine's impact on acute myeloid leukemia and the function of PRC1 complexes in cancer biology. They hold a PhD and are actively involved in collaborative research projects, including investigations into protein quality control mechanisms and the druggable targets in leukemia pathways. Their research has been published in high-impact journals such as Cell Reports , Blood , and eLife . Current affiliations include the University Medical Center Groningen (UMCG), where they conduct studies within the Faculty of Medical Sciences. No specific awards or grants are listed, but their extensive publication record highlights significant contributions to hematological and molecular oncology research.

Rolf Christoffersenمشاهده پروفایل

استاد آموزشی

• Plant Biochemistry
• Molecular Genetics
• Fruit Physiology
• +۵ مورد دیگر

Rolf Christoffersen is a Teaching Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of California, Santa Barbara (UCSB). He holds a Ph.D. from UCLA (1983) and conducted postdoctoral research at McGill University and UC Davis. His academic career at UCSB began in 1985. Christoffersen’s research focuses on plant and yeast metabolism, particularly fruit ripening in avocados and yeast fermentation volatiles. His lab investigates browning disorders in avocados, polyphenol oxidase activation, and CRISPR/Cas9 applications in industrial yeast strains. Concurrently, he leads STEM education initiatives to improve retention and success rates for at-risk undergraduate students through structured courses and mentorship programs. His research contributions span over four decades, with key studies on ethylene regulation in plant development, cellulase gene expression, and cytochrome P450 function. He has published extensively in journals like Postharvest Biology and Technology , Plant Physiology , and Proceedings of the National Academy of Sciences . Christoffersen’s educational work emphasizes scalable peer mentorship and course redesign to enhance equity in STEM. His programs aim to address systemic barriers faced by first-year students and underrepresented groups. He currently advises no named students but collaborates on grants related to both biological research and pedagogical innovation. His lab facilities are part of UCSB’s MCDB Department, supporting interdisciplinary studies in plant science and fermentation technology.

• Autoimmunity
• Rheumatology
• Inflammation
• +۳ مورد دیگر

Associate Professor Sean O'Neill is a rheumatologist affiliated with the Northern Clinical School at the University of Sydney. His research focuses on autoimmune diseases, particularly systemic lupus erythematosus (SLE), with an emphasis on disease activity states, clinical outcomes, and patient management strategies. Key areas of interest include lupus low disease activity state (LLDAS), damage accrual, and the impact of therapies on patient quality of life. Research Students: Mariya HAMID Grants: 2020 Faculty of Medicine and Health Strategic Grant His work spans translational research, clinical trials, and epidemiological studies, often involving multinational collaborations like the Asia Pacific Lupus Collaboration. Recent studies explore the efficacy of telehealth interventions and exercise therapies in SLE, as well as guidelines for perioperative drug management in inflammatory arthritis. Publications highlight longitudinal analyses of SLE progression, biomarker associations, and the role of endothelial protein C receptors in rheumatic diseases. Collaborations with institutions globally underscore his commitment to advancing clinical practice and patient care.

Peter Torleyمشاهده پروفایل

استاد

• Food Science and Technology
• Food Processing
• Grains
• +۱۱ مورد دیگر

Professor Peter Torley is a faculty member at the School of Science, RMIT University. He holds the rank of Professor and has extensive experience in food science and technology. His academic journey includes roles such as Associate Professor (2016–present), Senior Lecturer (2014–2016), and Adjunct Senior Lecturer at Charles Sturt University. His research focuses on food processing, texture modification for dysphagia management, and the application of spectroscopic techniques for food characterization. He leads projects on sustainable food technologies, including valorization of plant by-products and enhancing functional properties of starches. Educational background includes a doctoral degree from the University of Queensland (1991–1995). His teaching includes courses on food manufacturing, quality assurance, and sensory evaluation. Research interests span grains, meat, wine, extrusion, and synchrotron-based analysis. He actively collaborates on industry projects, such as developing high-CO₂ packaging and microbial biopreservatives for meat shelf-life extension. His work aligns with UN Sustainable Development Goals 2 (Zero Hunger), 3 (Good Health), 12 (Responsible Consumption), and 9 (Industry Innovation). Key research outputs include studies on starch nanoparticles, meat quality assessment via Raman spectroscopy, and texture-modified foods for dysphagia. His lab focuses on innovative food processing technologies and food safety solutions. He is open to supervising PhD and Master’s students in food science and technology.

Tian Liuمشاهده پروفایل

استادیار

• Neurodegenerative Diseases
• Mitochondrial Dysfunction
• Alzheimer’s Disease (AD)
• +۶ مورد دیگر

Tian Liu, PhD, is an Assistant Professor in the Department of Pathology at Case Western Reserve University School of Medicine. He specializes in neurodegenerative diseases such as Alzheimer’s, Frontotemporal dementia, and ALS, with a focus on mitochondrial dysfunction and genetic mechanisms. His work integrates multi-omics approaches (proteomics, transcriptomics) and gene therapy strategies like viral vectors (AAV). Dr. Liu leads an NIH-funded lab investigating mitochondrial dynamics, organelle crosstalk, and neuroprotective pathways. Education: PhD from Seoul National University (2014), postdoc training at USF Health Byrd Alzheimer’s Institute (2018). Research Interests: Mitochondrial dysfunction in aging-related diseases, genetic variants in amyloid-β pathways, TDP-43-tau crosstalk in AD, and therapeutic strategies targeting mitochondrial quality control. Recent NIH grants fund studies on mitochondrial mechanisms in neurodegeneration (R01AG086365, 2024–2029) and amyloid-β genetics (R03AG084948, 2024–2026). His lab employs patient-derived cellular models and mouse models to study mitochondrial phenotypes and develop therapies.

Gonzalo Blancoمشاهده پروفایل

مدرس ارشد

• Muscle Plasticity
• Muscle Biology
• Genetic Disorders
• +۴ مورد دیگر

Dr. Gonzalo Blanco is a Senior Lecturer in the Department of Biology at the University of York. His research focuses on understanding the mechanisms underlying skeletal muscle plasticity, particularly the role of Z-disc proteins like KY and ZAK in muscle adaptation and disease. He explores how mechanical stress signals trigger transcriptional changes and protein turnover via autophagy pathways. His work uses mouse, fish, and cellular models to study rare genetic myopathies, such as those caused by ZAK mutations. Collaborations include projects with Betsy Pownall investigating ZAK signaling pathways and muscle integrity. Teaching involves a module on human genetics, where students analyze pedigrees, calculate genetic risks, and use research papers to interpret disease mechanisms. He emphasizes hands-on lab techniques and innovative projects in science communication, such as creating media pieces to explain biomedical discoveries. Key grants include the CFH1 Research Project (2017–2018) on ZAK-linked myopathy models and C2D2 initiatives exploring Z-disc proteins' roles in muscle function. His research bridges mouse models and human conditions, aiming to identify therapeutic targets for rare muscle disorders.

Olivier Voinnetمشاهده پروفایل

استاد

• RNA Silencing
• Plant Biology
• Plant Immunity
• +۴ مورد دیگر

Prof. Dr. Olivier Voinnet is a Full Professor at the Department of Biology and Head of the Institute of Molecular Plant Biology at ETH Zürich. His research focuses on RNA silencing mechanisms in plants, particularly their roles in antiviral defense, developmental regulation, and epigenetic processes. Key areas include small RNA biogenesis, mobility, and functional interactions with viral pathogens. His work explores how plants utilize small RNAs (siRNAs, miRNAs) to combat viral infections, regulate gene expression, and maintain genome integrity. Notable contributions include studies on the suppression of RNA silencing by viral proteins and the systemic spread of small RNAs via phloem and plasmodesmata. Voinnet’s research integrates molecular genetics, biochemistry, and computational approaches to dissect RNA silencing pathways. His findings bridge basic biology with applications in agriculture and biotechnology, such as enhancing crop resistance to pathogens. Leading the Institute of Molecular Plant Biology, fostering interdisciplinary plant science research. Teaching courses in Plant Biology and Molecular Genetics at ETH Zürich. Publications highlight breakthroughs in understanding small RNA dynamics, including their roles in meristem activity, transposon silencing, and cross-kingdom RNA communication. His work underscores the importance of RNA-based regulatory networks in plant immunity and development.

• Cell Biology
• Endocytosis
• Membrane Dynamics
• +۵ مورد دیگر

Min Wu is an Associate Professor in the Department of Cell Biology at Yale University, part of the Yale School of Medicine. She holds affiliations with the Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) program, the Cell Biology Center, the Cancer Signaling Networks group, the Center for Biomedical Data Science, and the Molecular Cell Biology, Genetics, and Development program. Her research focuses on cellular oscillations, membrane curvature dynamics, and cell size homeostasis. Prior to Yale, she was an Associate Professor at the National University of Singapore and a National Research Foundation Fellow. Education: BSc in Chemistry from Peking University (2000), DPhil in Chemistry from Cornell University (2006). Postdoctoral training at Yale University under Pietro De Camilli. Her work bridges cell biology, biophysics, and systems biology, with key contributions to reconstituted endocytic systems and cortical wave mechanisms. Research Interests: Endocytic trafficking mechanisms, actin wave dynamics, phosphoinositide signaling, and the biophysical principles governing cell size and shape. Her lab investigates how oscillations and waves coordinate cellular processes, with implications for cancer signaling and developmental biology. Awards: Recognized as a National Research Foundation Fellow. Her research has been highlighted in high-impact journals like Nature Cell Biology, Developmental Cell, and Cell Reports. Collaborations span disciplines, including with the Mechanobiology Institute and the Center for Bioimaging Sciences. Labs/Teams: Leads the Wu Lab, which employs advanced microscopy and systems approaches to study single-cell dynamics. Engages in interdisciplinary projects, integrating computational modeling with experimental cell biology.

Alwena Morganمشاهده پروفایل

مدرس ارشد

• Neuroprotection
• Neurodegenerative Disorders
• Lipid Analysis
• +۳ مورد دیگر

Dr Alwena Morgan is a Senior Lecturer in Biomedical Sciences at Swansea University Medical School, part of the Faculty of Medicine, Health and Life Science. She specializes in neuroprotection, neurodegenerative disorders, and lipid analysis, particularly focusing on ghrelin's role in neurogenesis and Parkinson’s disease. A fluent Welsh speaker, she leads Welsh provision for undergraduate biomedical programs, ensuring eligibility for Welsh scholarships and bursaries. She has been nominated three times and won once for the SUMS Outreach Award for her work with bilingual school pupils in years 12 and 13. She collaborates closely with the Coleg Cymraeg Cenedlaethol to promote Welsh-medium education. Her research integrates mass spectrometry-based lipid analysis with neurodegenerative disease mechanisms, exploring ghrelin’s neuroprotective potential and mitochondrial dynamics in Parkinson’s models. Key contributions include developing protocols for mRNA analysis in human brain tissue and automated quantification of mitochondrial fragmentation. She also innovates in medical education, implementing flipped classrooms for biochemistry teaching. Research Themes: Neuroprotection, Neurodegeneration, Ghrelin Signaling, Lipidomics, Medical Education Notable Achievements: SUMS Outreach Award winner, 3 nominations, Welsh-medium curriculum development Collaborations: Coleg Cymraeg Cenedlaethol, Swansea Bay University Health Board Dr Morgan has supervised multiple PhD/MSc students investigating topics like ghrelin-GHS-R signaling in autophagy and biomarkers for dementia diagnosis. Her work bridges clinical and basic research, emphasizing translational outcomes for neurological conditions.

• Metabolomics
• Nanotechnology
• Environmental Science
• +۳ مورد دیگر

Dr. William Cheung is an Assistant Professor in the Applied Sciences Department at Northumbria University. His research spans metabolomics, nanotechnology, environmental science, and medical research. He holds a PhD in Chemistry from 2010. Key research focuses include metabolomic profiling of diseases (e.g., cystic fibrosis, glioblastoma), nanomaterial synthesis from biomass, and environmental contamination assessment using remote sensing. His work intersects with clinical applications, food science, and sustainable materials. Recent studies explore gut microbiota interactions with CFTR modulators, tart cherry's effects on metabolism, and mycoprotein's cardiovascular benefits. Collaborations span multidisciplinary teams in the UK and globally. No scientific awards are listed, but his research has been cited over 389 times. He actively publishes in journals like Nutrients , Environmental Sciences: Processes and Impacts , and International Journal of Molecular Sciences . His lab engages in metabolomics, nanotechnology development, and translational biomedical research without explicitly noted grants or lab names in the provided data.