جستجوی استاد راهنمای دانشگاهی

Dr. Chad J. Brenner is an Associate Professor in the Department of Otolaryngology-Head and Neck Surgery and Pharmacology at the University of Michigan Medical School. He also directs the U-M Program in Cellular and Molecular Biology, the Otolaryngology Clinical Laboratory (CLIA), and the Head & Neck Oncology Program. His research focuses on developing liquid biopsy tools for cancer detection and precision therapy, particularly in HPV-driven head and neck cancers. Key roles include membership in the Rogel Cancer Center, Kresge Hearing Research Institute, and Center for Computational Medicine & Bioinformatics. Education: B.S. in Biomedical Engineering, M.S. in Bioelectrical Engineering, and Ph.D. in Cellular and Molecular Biology from the University of Michigan, with doctoral work on prostate cancer mechanisms. Research Interests: HPV integration and cancer heterogeneity Urine- and blood-based liquid biopsies for real-time cancer monitoring Combination immunotherapy strategies for improving checkpoint inhibitor responses Genetic engineering to identify cancer vulnerabilities Clinical trial innovation for adaptive therapies Recent Work Highlights: Development of the MyHPVscore blood test for HPV-related head and neck cancer detection, and exploration of tumor-immune interactions through PD-L1 and T-cell profiling. Ongoing projects include PET-guided radiotherapy optimization and multi-omics analyses of tumor heterogeneity. Labs & Teams: Leads the Michigan Otolaryngology and Translational Oncology (MiOTO) lab and collaborates with interdisciplinary teams across computational medicine, immunology, and clinical oncology.

• Head and Neck Cancer
• HPV-Driven Oncogenesis
• Liquid Biopsy Technologies
• +۵ مورد دیگر

Gregory C. Rogers is a Professor in the Department of Cellular and Molecular Medicine at the University of Arizona, with additional appointments in the BIO5 Institute, Cancer Biology GIDP, and Genetics GIDP. He specializes in molecular mechanisms governing centriole duplication and centrosome instability in cancer progression. Education: BA in Biology from the University of Rochester PhD in Cell and Developmental Biology from University of California, Davis Postdoctoral training at Albert Einstein College of Medicine and University of North Carolina, Chapel Hill His research focuses on centriole duplication control, centrosome amplification/loss in prostate cancer, and the role of Polo-like kinase 4 (Plk4) in mitotic errors. Articles from 2010-2025 highlight his work on centrosome dynamics, cancer-related chromosomal instability, and Drosophila model applications. Recent studies (2023-2025) explore PIM kinase inhibition in immunotherapy, Plk4 regulation, and centrosome loss as a driver of prostate malignancy. Earlier work (2010-2019) established foundational knowledge of centriole assembly and condensin II function.

• Centriole Duplication
• Centrosome Instability
• Chromosomal Instability (CIN)
• +۶ مورد دیگر

Jussi Taipale is a Professor of Medical Systems Biology at Karolinska Institutet and holds professorships at University of Helsinki. His research focuses on transcription factor binding mechanisms , cancer genomics , and gene regulatory networks . The interdisciplinary Taipale Lab operates across three international locations: Wellcome Sanger Institute (UK), Karolinska Institutet (Sweden), and University of Helsinki (Finland), with over 20 members including senior scientists, postdoctoral fellows, and graduate students. Ph.D., University of Helsinki (1996) Postdoctoral training: University of Helsinki, Johns Hopkins University Research spans transcription factor cooperativity , epigenetic regulation , chromatin accessibility , and noncoding mutation analysis . Key methodologies include HT-SELEX , CUT&RUN , ATI assays , and CRISPR-based functional genomics . The lab has significantly advanced understanding of Myc-driven oncogenesis , TF-nucleosome interactions , and dinucleotide specificity mechanisms . Notable discoveries include chromatin context-dependent enhancers , water-mediated DNA recognition , and novel composite transcription factor motifs . The group maintains active collaborations across Europe and has trained numerous alumni now leading academic and industry positions worldwide.

• Gene regulation
• Transcription factors
• Systems biology
• +۴ مورد دیگر

Chi Wang, Ph.D., is Professor of Internal Medicine and Statistics at the University of Kentucky, Associate Director of the Biostatistics & Bioinformatics Shared Resource, and a lead computational scientist within the Markey Cancer Center. With an h-index of 39 and >5,300 citations, he develops cutting-edge survival-analysis and high-dimensional-omics methods that are translated into prostate, breast, lung and neuroblastoma trials. Education: Ph.D. Biostatistics, Johns Hopkins University, 2009 M.S. Statistics, Peking University, 2003 B.S. Mathematics, Peking University, 2001 Research Focus: Wang’s group integrates Bayesian statistics, machine-learning and single-cell sequencing to model tumor evolution, drug resistance and biomarker-driven adaptive trials. Major themes include enzalutamide resistance in prostate cancer, PLK1-mediated immune evasion in lung adenocarcinoma, obesity-adipose drivers of breast cancer, and epigenetic reprogramming of tumor-infiltrating lymphocytes. Recent Article Trends (2023-2025): Fifteen showcased papers reveal a dual trajectory—(1) mechanistic dissection of kinases (PLK1, DDR1, ABL1/2) and metabolic enzymes (FASN, NNMT, HSP47) that orchestrate resistance and metastasis, and (2) probabilistic algorithms for temporal mutation ordering, biomarker evaluation and single-cell deconvolution. Overarching keywords are precision oncology, drug resistance, tumor micro-environment, and computational systems biology. Funding & Awards: He is PI/co-I on 152 grants (32 active) from NCI, ACS, V Foundation, etc., totaling >$30 M direct costs. Highlights include NCI U01 for predictive biomarkers, American Cancer Society award on collagen lysyl hydroxylase metastasis drivers, and NCI R01s targeting NNMT in triple-negative breast cancer and TIL epigenetic reprogramming in NSCLC. Student & Team Mentorship: Wang trains a large multi-disciplinary cohort of Ph.D. students, post-docs and clinical fellows who routinely lead first-author papers and are funded on his grants. His lab sits within the Markey Cancer Center’s Molecular & Cellular Oncology program and the Center for Computational Sciences, fostering daily bench-to-bedside collaboration.

• Cancer Biostatistics
• Bioinformatics
• Survival Analysis
• +۱۰ مورد دیگر

Associate Professor Fatemeh Vafaee is a leading researcher at the University of New South Wales (UNSW) , holding appointments as Associate Professor in the School of Biotechnology and Biomolecular Sciences (BABS) and Deputy Director (Science) of the UNSW AI Institute . She previously served as Deputy Director of the UNSW Data Science Hub (uDASH) and has held academic positions at the University of Toronto and the University of Sydney. PhD in Artificial Intelligence from University of Illinois at Chicago Postdoctoral Fellowships at University of Toronto and University of Sydney Founded the AI-Enhanced Biomedicine Laboratory in 2017 Her research focuses on deploying advanced AI techniques to address biomedical challenges through: Biomarker Discovery for cancer and neurodegenerative diseases Single-Cell Multi-Omics data integration and analysis Computational Drug Repositioning and network pharmacology Multi-Omics Data Fusion and temporal network modeling Recent publications demonstrate expertise in liquid biopsy development , single-cell imaging , and AI-driven cancer diagnostics . Her methodological contributions include novel deep learning architectures for omics data analysis and graph neural networks for drug synergy prediction. Scientific accolades include: Winner, Women in AI Asia-Pacific Health Award (2023) Runner-Up, WAI-APAC Innovator of the Year (2023) Top 10 Women in AI in Asia-Pacific (2023) Australian Bioinformatics and Computational Biology Society Research Excellence Award (2023) She supervises PhD candidates across computational biomedicine and AI in healthcare , with significant grant achievements exceeding $17M in competitive funding, including schemes from ARC Discovery , NHMRC , and Medical Research Future Fund .

• Artificial Intelligence
• Machine Learning
• Systems Biology
• +۵ مورد دیگر

Prof. Maria Paola Paronetto is an Associate Professor at the Department of Human Motor Sciences and Health, University of Rome 'Foro Italico'. Her research focuses on RNA metabolism and alternative splicing, particularly in cancer and neurodegenerative diseases like Ewing Sarcoma and Amyotrophic Lateral Sclerosis (ALS). She investigates the roles of RNA binding proteins (RBPs) and signaling pathways in disease pathogenesis, with an emphasis on developing novel therapeutic targets. Research Areas: RNA processing, molecular oncology, neurodegeneration, splicing regulation Her work includes projects funded by grants such as the AIRC Investigator Grant (IG21877) and PRIN 202224MK8Z. Prof. Paronetto collaborates on international initiatives like the European Master's in Health and Physical Activity. She teaches courses in research methodology and general biology at the university. Key contributions include identifying the DHX9/KDM2B complex as a therapeutic target in Ewing Sarcoma and elucidating exercise impacts on ALS progression in mouse models. She is a member of review groups for international programs and contributes to translational research initiatives.

• RNA Metabolism
• Alternative Splicing
• Molecular Oncology
• +۴ مورد دیگر

Timothy J Triche is Professor of Pathology at the Keck School of Medicine, University of Southern California. He directs research in cancer genomics, epigenetics, and bioinformatics, with emphasis on pediatric malignancies. His laboratory develops computational tools for genomic analysis and focuses on translating molecular discoveries into clinical diagnostics. Research spans pediatric acute myeloid leukemia, prostate cancer, and sarcoma biology, integrating multi-omics approaches. Key interests include liquid biopsy development, epigenetic dysregulation, and gene fusion mechanisms in oncogenesis. Publications demonstrate consistent focus on molecular diagnostics and bioinformatic innovation, with recent work advancing single-cell analysis methodologies and non-invasive cancer profiling. Earlier foundational studies established mechanisms of fusion oncoproteins in sarcomas.

• Cancer Genomics
• Epigenetics
• Bioinformatics
• +۲ مورد دیگر

Colum Walsh is a Professor at Linköping University's Department of Biomedical and Clinical Sciences (BKV), affiliated with The Division of Cell and Neurobiology (CNB) and SciLifeLab Linköping. His research focuses on immunology, epigenetics, mental health, and genetics, with particular emphasis on immune responses to viral infections, epigenetic regulation in development, and mental health epidemiology among student populations. He contributes to national research initiatives like the Precision Omics Initiative Sweden (PROMISE), integrating genomic and clinical data. Key research areas include T cell memory profiling in SARS-CoV-2 patients, epigenetic effects of nutritional interventions during pregnancy, and biomarker discovery for disease severity prediction. His work bridges basic science and clinical applications, addressing topics from cellular senescence mechanisms to the impact of exercise on epigenetic aging markers in muscle tissue. Collaborations involve multidisciplinary teams across Swedish academic institutions. Recent publications highlight contributions to understanding Omicron variant immune dynamics, folic acid's role in neurocognitive development, and miRNA regulation in prostate cancer. While no specific awards are listed, his active research portfolio reflects sustained academic engagement in high-impact areas of biomedical science.

• Immunology
• Epigenetics
• Mental Health
• +۳ مورد دیگر

João Carlos Lopes de Carvalho is a Full Professor at the Faculty of Science and Technology of the University of Coimbra, Portugal, where he has held academic positions since 1987. He was promoted to Associate Professor in 2003 and attained Full Professor status in 2022. His research spans computational biology, biophysical modeling of cancer, and experimental particle physics, with extensive participation in international collaborations including CERN (CPLEAR, ATLAS) and DESY (HERA-B). PhD in Experimental Particle Physics, University of Liverpool (1994) Aggregate Title (Habilitation), University of Coimbra (2003) Bachelor’s Degree in Physics, University of Coimbra (1987) His research focuses on the computational modeling of biological systems, particularly the bioelectric mechanisms underlying cancer initiation and progression. He develops discrete models such as cellular automata and cellular Potts models to simulate tissue dynamics in 2D and 3D, with applications in bladder and prostate cancer. Earlier in his career, he contributed to particle detector development, data acquisition, and physics analysis in high-energy experiments. The recent trends in his publication record show a strong emphasis on multiscale modeling of tumor growth, angiogenesis, and the role of bioelectricity in carcinogenesis. His work integrates computational simulations with biological insights, targeting early cancer detection and therapeutic strategies. Articles are published in high-impact journals such as Scientific Reports , PLOS Computational Biology , and Bulletin of Mathematical Biology . Supervised or co-supervised 4 PhD theses and 19 master’s dissertations Participated in over 50 research projects, coordinating 9 Principal investigator on grants including FCT projects PTDC/EMD-TLM/7289/2020 and PTDC/BIA-CEL/31743/2017 Involved in major collaborations: CERN (ATLAS, CPLEAR), DESY (HERA-B), SNO+ João Carlos Lopes de Carvalho has been a key figure in advancing computational approaches in oncology and biophysics. His work bridges physics, engineering, and life sciences, contributing to both fundamental understanding and potential clinical applications in cancer research.

• Computational Biology
• Biophysical Modeling
• Cancer Modeling
• +۱۲ مورد دیگر

Carman Man-chung Li is an Assistant Professor of Cancer Biology at the Perelman School of Medicine, University of Pennsylvania. He is also an Assistant Investigator at the Abramson Family Cancer Research Institute and a Core Investigator at The Basser Center for BRCA. His research focuses on hereditary cancer mechanisms, particularly how heterozygous loss-of-function mutations in tumor suppressor genes drive early tumorigenesis beyond the classical 'two-hit' hypothesis. Education: A.B. in Molecular Biology (High Honors), Princeton University (2009); Ph.D. in Biology, Massachusetts Institute of Technology (2015) Using genetically engineered mouse models, organoid cultures, and multi-omics, his lab investigates gene haploinsufficiency effects, epigenetic alterations, and stromal-epithelial interactions. Recent work includes mapping early tumor drivers in BRCA1-mutant models and cross-ancestry cancer risk stratification. Scientific Affiliations: Abramson Family Cancer Research Institute The Basser Center for BRCA Graduate Groups: Pharmacology, Cell and Molecular Biology His lab collaborates with the Penn Medicine Biobank, VA Million Veterans Program, and EDISYN Consortium for translational studies in Li-Fraumeni Syndrome and BRCA-related cancers. Funding sources include the National Cancer Institute, Prostate Cancer Foundation, and Li Fraumeni Syndrome Association.

• Cancer Biology
• Genetics
• Molecular Biology
• +۳ مورد دیگر

Reuben Young is an Associate Research Fellow at the University of Wollongong's School of Chemistry and Molecular Bioscience within the Faculty of Science, Medicine and Health. His work focuses on advancing mass spectrometry-based technologies for lipidomics and metabolomics, particularly in studying disease mechanisms such as osteoarthritis, cancer, and neurodegenerative conditions. Key research themes include spatial metabolite imaging, lipid isomer characterization, and development of novel analytical techniques like ozone-induced dissociation and MALDI-2 oversampling. His research has been supported by grants such as 'Sparking and fading: Spatially linking the complex metabolic activities of neurotransmitters and lipids during cell death' (2023-2024), investigating neurodegeneration mechanisms, and an equipment grant for mass spectrometry facility maintenance (2023). He collaborates extensively with peers globally, evidenced by co-authorships on over 30 publications. Recent publications emphasize lipidomic profiling in cancer progression, enzymatic activity mapping in osteoarthritis, and peptide-based cancer therapies. His work bridges fundamental analytical chemistry with biomedical applications, contributing to both instrumentation innovation and disease biomarker discovery.

• Mass Spectrometry
• Lipidomics
• Metabolomics
• +۳ مورد دیگر

Elizabeth Marsh is an Associate Professor in Cellular and Molecular Biology at the College of Science and Engineering. Her research focuses on the intersection of molecular biology, virology, and immunology, particularly investigating the role of Human Papillomavirus (HPV) in cancer development and immune responses to viral infections. Key Research Areas: HPV-related carcinogenesis, inflammatory lung disease, immune signaling pathways, and model organisms (e.g., zebrafish, Caenorhabditis elegans ). Recent publications highlight her work on HPV prevalence in oral cancers, viral oncogenesis, and regulatory mechanisms in airway immune responses. She has no documented scientific awards or student advisories listed in the provided data.

• Molecular Biology
• Cellular Biology
• Virology
• +۳ مورد دیگر

Erik Dassi is an Associate Professor at the Department of Cellular, Computational and Integrative Biology (CIBIO) within the University of Trento. His research focuses on RNA biology, particularly investigating RNA structure-functional relationships, translational control mechanisms, and their implications in cancer, neurodegenerative diseases, and genetic disorders. He specializes in exploring how RNA modifications, G-quadruplex structures, and post-transcriptional regulatory networks drive disease processes and therapeutic resistance. Teaching activities include courses on Computational Biology, Cancer Genomics, Genomics Technologies, Programming, and Scientific Programming. His work emphasizes integrative approaches combining experimental and computational methods, such as polysomal profiling, allele-specific proteomics, and single-cell transcriptomics. Key research themes include: RNA G-quadruplex regulation of mitochondrial translation and energy metabolism ( n =3 articles in 2025), YTHDF proteins as tumor drivers in m6A pathways ( n =2 articles in 2024), and circular RNA roles in Huntington’s disease ( n =4 articles across 2021-2024). His work highlights translational reprogramming in cancer therapy resistance and RNA-based biomarker discovery.

• Ribonucleic acid (RNA)
• Data Analysis
• Bioinformatics
• +۱۲ مورد دیگر

Dr. Anja Rockstroh is a Research Fellow at the Queensland University of Technology (QUT), affiliated with the School of Biomedical Sciences. Her work focuses on bridging biochemistry and bioinformatics to translate genomic data into biological insights, particularly in prostate cancer research. She holds a doctorate in biochemistry from Friedrich Schiller University Jena (2007) and has over 15 years of experience in cancer genomics. Dr. Rockstroh has contributed to projects investigating cellular adaptive pathways in castrate-resistant prostate cancer, developing RNAseq and microarray analysis pipelines. She has published 17 peer-reviewed articles and secured grants including a $250K PCFA grant (2010) and a $200K Cancer Council Queensland grant. Education: Dr.rer.nat in Biochemistry, Friedrich Schiller University Jena (2007) Research Focus: Prostate cancer transcriptomics, lipid metabolism, and drug resistance mechanisms Grants: Co-investigator on PCFA-PG 4410 (2010) and APP1080379 (Cancer Council Queensland) Her research emphasizes translational applications, including identifying novel treatment resistance pathways through large-scale transcriptome profiling of over 600 prostate cancer samples. She collaborates with teams like APCRC-Q and the MRTA project, advancing understanding of androgen response pathways and metabolic reprogramming in cancer progression.

• Cancer Biology
• Prostate Cancer Research
• Transcriptomics
• +۷ مورد دیگر

Dr. Daniel Stovall is an Assistant Professor of Biology at Winthrop University's College of Arts and Sciences. He holds a B.S. in Biology from Campbell University (2009) and a Ph.D. in Cancer Biology from Wake Forest University (2014). Prior to joining Winthrop in 2019, he served as an Assistant Professor at North Carolina Wesleyan University for five years. His research focuses on epigenetic mechanisms in cancer progression, particularly involving proteins like YY1 and EZH2, and the role of G-quadruplexes in gene regulation. He actively involves undergraduate and Master’s students in his research, leading to student presentations at conferences such as the National IDeA Symposium of Biomedical Research Excellence. Dr. Stovall teaches courses in cell biology, genetics, and cancer biology. He has authored over 20 peer-reviewed articles in disciplinary journals and pedagogical papers. His work bridges molecular mechanisms and translational research, emphasizing the interplay between epigenetics and oncogenesis. While no specific awards are listed, his contributions to undergraduate research and cancer biology are highlighted through collaborative student projects. His academic journey includes prior teaching and research at NC Wesleyan University, and his current role at Winthrop underscores a commitment to both education and cutting-edge research in cancer biology.

• Cell and Molecular Biology
• Cancer Biology
• Epigenetics