Prof. Dr. Sven Diederichs is a Tenured Full Professor (W3) and Division Head of the Division of Cancer Research at the Department of Thoracic Surgery , University Hospital Freiburg. He coordinates the DKTK Program 'Exploitation of Oncogenic Mechanisms' and leads the Center for Translational Cell Research (ZTZ). His work bridges high-throughput functional genomics with precision oncology. Education: PhD (Dr. rer. nat.) in Hematology/Oncology, University of Münster; Biochemistry, University of Witten/Herdecke and Eberhard-Karls-Universität Tübingen Postdoctoral Training: Harvard Medical School/Massachusetts General Hospital Cancer Center His research focuses on functional characterization of cancer-derived mutations , particularly in the FGFR family, to inform targeted therapies. He developed saturation mutational scanning libraries to map drug resistance/sensitivity across 30,000 mutations and explores non-canonical mutations like nonstop extensions and synonymous variants. Recent work highlights include comprehensive studies on RNA-dependent proteins (R-DeeP), lincNMR's role in nucleotide metabolism, and systematic analysis of mutation-driven tumorigenesis. These efforts aim to establish clinical decision support systems for precision oncology. Scientific Awards : FEBS Anniversary Prize (2016) Liver Cancer Research Award (2014) Dr. Hella Bühler Prize (2013) Binder Innovation Prize (2012)







