جستجوی استاد راهنمای دانشگاهی

Joseph A. Gogosمشاهده پروفایل

استاد

• Schizophrenia Research
• Genetics of Psychiatric Disorders
• Neural Circuit Mechanisms
• +۵ مورد دیگر

Joseph A. Gogos, MD, PhD is a Professor of Neuroscience and Physiology and Cellular Biophysics at Columbia University's Vagelos College of Physicians and Surgeons. He serves as Codirector of Columbia's Stavros Niarchos Foundation Center for Precision Psychiatry and Mental Health and is a Principal Investigator at Columbia's Zuckerman Mind Brain Behavior Institute. Dr. Gogos's research focuses on understanding the molecular, cellular, synaptic and circuit mechanisms that give rise to schizophrenia. His work combines human genetic studies with animal models to trace how specific genetic mutations lead to psychiatric disorders. He has made significant contributions to identifying rare de novo and inherited mutations that increase schizophrenia risk and has developed relevant model systems to understand their impact on neural mechanisms. His laboratory has published extensively in top journals including Neuron, Nature, and Cell, with recent work focusing on brain organoids, neural circuitry, and precision psychiatry approaches. Dr. Gogos's research has demonstrated the potential to reverse schizophrenia-related phenotypes in animal models, paving the way for new therapeutic strategies. His notable awards include: Brain & Behavior Research Foundation Distinguished Investigator Award (2017) Columbia University Dr. Harold and Golden Lamport Research Award in Clinical Sciences (2004) Dr. Gogos actively mentors students and postdoctoral researchers through the Doctoral Program in Neurobiology and Behavior and maintains an active laboratory recruiting scientists with expertise in genome engineering, behavioral experimentation, electrophysiology, and neural circuit manipulation. His collaborative work at the Zuckerman Institute brings together diverse scientific perspectives to address the complex challenges of psychiatric disorders. His laboratory is located at the Jerome L. Greene Science Center as part of the Mortimer B. Zuckerman Mind Brain Behavior Institute, providing state-of-the-art facilities for neuroscience research.

Mukesh Dhamalaمشاهده پروفایل

استاد

• Neural mechanisms of human decision-making
• Epileptic seizures
• Brain restoration after stroke and rehabilitative treatments
• +۵ مورد دیگر

Dr. Mukesh Dhamala is a Professor of Physics and Neuroscience at Georgia State University's College of Arts & Sciences. His research focuses on integrating physics and brain science to improve human health, with expertise in neural mechanisms of decision-making, epilepsy, brain restoration post-stroke, and neuronal network dynamics. Neural mechanisms of human decision-making Epileptic seizures and brain network analysis Rehabilitative treatments and brain restoration Neuronal network oscillations and synchronization Nonlinear dynamics in neural systems His work employs advanced methodologies such as spectral Granger causality for analyzing brain imaging and electrophysiological data. Dr. Dhamala received the prestigious NSF CAREER award in 2010 for his research program on brain network activity during perceptual decision-making. Recent publications highlight trends in brain network analysis applied to diverse contexts including esports, schizophrenia, and stroke rehabilitation. His studies investigate the impact of action video gaming on brain structure, functional connectivity in neurological disorders, and dynamic causal modeling in cognitive tasks. Scientific awards include: NSF CAREER award (2010) Dr. Dhamala's research has been supported by grants related to brain network activity analysis and its clinical applications. He actively publishes in interdisciplinary journals covering neuroscience, computational modeling, and neuroimaging techniques.

Deni S. Galileoمشاهده پروفایل

استاد

• Cell Migration
• Neurobiology
• Developmental Biology
• +۳ مورد دیگر

Deni S. Galileo is a Professor in the Department of Biological Sciences at the University of Delaware. His research focuses on cell migration mechanisms in the developing brain and malignant gliomas, utilizing chick embryo models and retroviral gene transfer technologies. His work explores how integrins, extracellular matrix molecules, and adhesion proteins like L1CAM regulate normal and abnormal cell migration. Key projects include developing novel models for studying glioma invasiveness and breast cancer brain metastases, and investigating the role of QSOX1 and PMCA4 in tumor progression. Education: B.A., New College of Florida Ph.D., University of Florida College of Medicine and Whitney Laboratory Postdoctoral Research, Washington University School of Medicine (St. Louis) Research interests span developmental neurobiology, tumor biology, and gene therapy. Current projects include: Control of glioma invasiveness via L1CAM Integrins' roles in neuronal migration and survival Ex vivo analysis of glioblastoma behavior using chick embryos His lab has pioneered the use of replication-competent retroviral vectors and in ovo electroporation for widespread protein misexpression in developing brains. Collaborations with Dr. John Koh (Chemistry and Biochemistry) explore axon outgrowth on gene-patterned cell monolayers. Lab Resources: Office 232 Wolf Hall, Lab 248 Wolf Hall Teaching: Courses include Cell Biology (BISC 305), Developmental Neurobiology (BISC 439/639), and Special Topics in Modern Biological Microscopy (BISC 400). Notable contributions include establishing chick embryo models for studying glioma and breast cancer metastasis to the brain, and discovering roles for integrin α6β1 and α8β1 in cell migration and survival.

Lani Wuمشاهده پروفایل

استاد

• Systems Biology
• Cell Signaling
• Cancer Biology
• +۷ مورد دیگر

Dr. Lani Wu is a Professor in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF), affiliated with the School of Pharmacy. She leads the Altschuler & Wu Laboratories , focusing on systems biology, cell signaling, and drug discovery. Her work integrates experimental biology, mathematics, and computational methods to study cellular individuality, collective behaviors, and drug resistance mechanisms. Key projects include high-throughput screening platforms, cancer persister cell mechanisms, and mathematical modeling of biological networks. Education: PhD in Mathematics, University of California, San Diego (1990) Masters in Mathematics, University of California, San Diego (1987) Bachelor of Arts in Mathematics, Taiwan University (1985) Research Interests: Dr. Wu’s research spans systems biology, cell polarity, and computational approaches to drug discovery. She investigates how biological networks rewire during disease, leveraging machine learning and image analysis to uncover design principles of biological systems. Current projects include modeling cancer drug resistance, identifying compounds for acute hypoxic stress, and developing tools for spatial transcriptomics. Publications: Her work emphasizes drug discovery, cancer biology, and cell signaling. Recent efforts highlight techniques like phenopushing platforms, high-content screening, and spatial analysis of cell morphologies. These studies aim to accelerate therapeutic development and understand cellular adaptation under stress. Affiliations: She is part of the Biological and Medical Informatics Graduate Program and the Quantitative Biosciences Institute (QBI) at UCSF, reflecting her interdisciplinary approach. Labs/Teams: The Altschuler & Wu Laboratories combine experimental and computational expertise to address complex biological questions, with particular emphasis on translational research in oncology and systems biology.

• Ion Transport
• Neurobiology
• Cell Biology
• +۳ مورد دیگر

Thomas J. Jentsch is a Professor and Head of the Jentsch Group at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin. He holds dual doctoral degrees in Medicine and Physics from Freie Universität Berlin, with postdoctoral training in molecular cell biology at MIT/Whitehead Institute. His research focuses on ion transport mechanisms across cellular membranes, leveraging genetic mouse models and electrophysiological techniques. Key areas include CLC chloride channels/transporters, volume-regulated anion channels (VRAC/LRRC8), and acid-sensitive ASOR/TMEM206 channels. His work bridges molecular studies with systemic physiology, elucidating roles in neurodegeneration, epilepsy, deafness, osteopetrosis, and immune responses. Notable contributions include the discovery of VRAC (2014) and ASOR (2019), which revealed critical functions in tumor drug resistance, insulin secretion, and innate immunity. Current projects explore structure-function relationships of ion channels and their roles in organ-specific pathologies. Educational background: Medicine & Physics (Freie Universität Berlin), postdoctoral research at MIT/Whitehead Institute and ZMNH Hamburg. He transitioned to FMP/MDC Berlin in 2006, becoming a leader in chloride transport research. His lab employs interdisciplinary approaches combining genetics, biochemistry, and systems biology. Research interests span ion channel regulation, endosomal-lysosomal biology, and translational medicine. Recent work highlights VRAC’s role in cGAMP transport and immune signaling, as well as ASOR’s contributions to cellular pH homeostasis. Collaborations with groups like Xiao’s lab have advanced understanding of antiviral immunity pathways. Lab members include senior scientists Rosa Planells-Cases and Maya Polovitskaya, postdocs Sumanta Kar and Aleksandra Garifulina, and PhD students Tanushka Rana and Franziska Schmitt. Technical staff supports advanced imaging and molecular biology. Future directions emphasize structural biology of ion channels, clinical implications of VRAC/ASOR mutations, and leveraging mouse models for disease mechanisms. The lab actively seeks interdisciplinary postdocs to explore novel ion transport roles in health and disease.

• Neurobiology
• Cell Biology
• Biomedical Imaging
• +۳ مورد دیگر

Dr. Simone Mortal is a Postdoctoral Researcher at the Institute of Photonic Sciences (ICFO), part of the SLN - Team Loza research group. They hold a PhD in Neurobiology from the International School for Advanced Studies (Italy). Their work focuses on advanced imaging techniques and cellular neurobiology, with specialties in super-resolution imaging, multiphoton microscopy, and confocal microscopy. Research interests include mechanisms of glioblastoma replication, neuronal mechanotransduction, microtubule dynamics in neurodegenerative diseases, and cytoskeletal roles in neuronal development. Dr. Mortal's research bridges biophysics and neuroscience, addressing fundamental questions about cellular signaling and disease mechanisms. They are based in Barcelona, Spain, and can be reached at Simone.Mortal@icfo.eu. Education: PhD in Neurobiology (International School for Advanced Studies, Italy). Research Themes: Investigating calcium signaling in neurodegeneration, mechanosensitive pathways in neurons, and actin dynamics during neuronal maturation. Their studies employ cutting-edge microscopy techniques to visualize cellular processes at high resolution, with a focus on glioma-derived exosome effects, growth cone mechanics, and cytoskeletal scaffolding in neural development. Labs/Teams: Active member of the SLN - Team Loza group at ICFO, specializing in neurobiophotonics and cellular imaging.

Ullas Pedmaleمشاهده پروفایل

دانشیار

• Plant Biology
• Environmental Science
• Molecular Biology
• +۳ مورد دیگر

Ullas Pedmale is an Associate Professor at Cold Spring Harbor Laboratory (CSHL), leading the Pedmale Lab. His research focuses on understanding how environmental cues, such as light and temperature, modulate plant growth and development. This work has significant implications for agriculture and climate resilience. Pedmale earned his Ph.D. in Biological Sciences from the University of Missouri (2008) and completed postdoctoral training at the Salk Institute under Joanne Chory. He is also an Adjunct Faculty Member at Stony Brook University. His research interests include plant-environment interactions, light signaling pathways, and the molecular mechanisms underlying plant adaptation. Key projects involve studying shade avoidance responses, DNA damage repair in plants, and the role of histone modifications in flowering time regulation. Pedmale’s lab utilizes advanced technologies like state-of-the-art growth chambers to simulate climate change effects on plants. Notable achievements include the NIH Outstanding Investigator Award (2017) and recognition for groundbreaking work on plant photoreceptors. His recent publications highlight discoveries in RNA methylation, ubiquitin regulation, and epigenetic mechanisms controlling plant growth. Pedmale has mentored numerous graduate students and postdoctoral researchers, fostering a collaborative environment focused on advancing plant science. Lab activities emphasize interdisciplinary approaches, combining genetics, molecular biology, and computational tools. Current projects explore how plants integrate light and temperature signals to optimize resource allocation, with potential applications in crop improvement. The lab’s innovations, such as rapid protein expression in tobacco for pandemic response, demonstrate versatility in addressing global challenges.

• Parkinson's Disease
• Neurodegenerative Diseases
• Neuroscience
• +۷ مورد دیگر

Professor Kay Double is a member of the Brain and Mind Centre and the Theme of Neuroscience within the School of Medical Sciences at the University of Sydney. Her research focuses on the interplay between neuropathological findings and quantitative neurochemistry, particularly investigating disease mechanisms in Parkinson’s disease. She has been funded by prestigious fellowships including the Alexander von Humboldt Foundation and consecutive Australian Research Fellowships. Her work challenges previous dogma about neuromelanin’s role in Parkinson’s, demonstrating its neuroprotective function in healthy cells and its dysregulation in disease contexts. Her current research projects explore copper dyshomeostasis and SOD1 proteinopathy in Parkinson’s and ALS, emphasizing translational research applications. Collaborations include interdisciplinary teams working on molecular pathways, diagnostic tools, and therapeutic strategies. Key approaches in her work include aetiological studies, cellular metallation analysis, and 3D neurochemical imaging. Scientific Awards: Alexander von Humboldt Research Fellowship (Germany) Australian Research Fellowships Advising and Grants: Professor Double advises current PhD student Anne LI. She has secured grants from organizations like the National Health and Medical Research Council (NHMRC), Motor Neurone Disease Research Institute of Australia, and the University of Sydney. Her grants include projects on SOD1 assays, copper pathways, and Parkinson’s diagnostics. Labs/Teams: She is part of the Brain and Mind Centre, collaborating with researchers such as Dr. Hare, Dr. Trist, and Dr. Genoud on projects involving metal-binding proteins, neurodegenerative mechanisms, and translational neuroscience.

• Neurological Disorders
• Speech Pathology
• Healthcare Communication
• +۳ مورد دیگر

Sarah El-Wahsh is a Lecturer in Speech Pathology at the Sydney School of Health Sciences, part of the Faculty of Medicine and Health at the University of Sydney. She holds a PhD (2022) and a Bachelor of Applied Science (Honours 1) in Speech Pathology (2017), graduating with the University Medal, Dean’s Scholar Award, and Speech Pathology Australia’s top student honor. Her expertise lies in adult speech pathology, particularly neurological disorders like motor neurone disease, Parkinson’s, dementia, and multiple sclerosis (MS), alongside aged care, palliative care, and communication neuroscience. Research interests include progressive neurological diseases, advanced communication skills for healthcare professionals, interdisciplinary care models, and motor speech disorders. She has received multiple awards, including the University of Sydney Teaching Award (2024), RTP Scholarship (2019–2022), and clinical excellence recognitions. Her work bridges clinical practice and research, emphasizing person-centered care and evidence-based interventions. Publications focus on communication impairments in MS, including CLAMS/SMS assessment tools and patient-centered strategies. Key articles analyze communication deficits’ impact on employment and cognitive function. Awards highlight both clinical and academic contributions, with travel grants supporting international conference participation. As an educator, she supervises clinical placements and enhances student preparedness for healthcare roles. Her advocacy for communication access and clinician training in motor neurone disease reflects her commitment to improving patient care through interdisciplinary collaboration.

Peter Larssonمشاهده پروفایل

استاد

• Ion Channel Research
• Cardiac Electrophysiology
• Neurobiology
• +۳ مورد دیگر

Professor Peter Larsson is affiliated with Linköping University's Department of Biomedical and Clinical Sciences, part of the Faculty of Medicine and Health Sciences. He holds a position within the Division of Cell and Neurobiology, focusing on ion channel research with clinical applications. His work bridges basic science and translational medicine, particularly in cardiac electrophysiology and neurobiological mechanisms. Education: Not explicitly detailed in provided texts. Research Interests: Larsson's research centers on ion channel dysfunction in disease states, including arrhythmias and epilepsy. He investigates lipid-channel interactions, drug mechanisms (e.g., propofol's effects on epilepsy), and genetic mutations' impact on cardiac and neuronal ion channels. His recent breakthrough demonstrated propofol's ability to restore function in epilepsy-linked ion channels, published in Nature . Publications Trends: Recent work emphasizes translational drug discovery and understanding channelopathies, with contributions to eLife , British Journal of Pharmacology , and Nature . Key themes include SCN5A mutation characterization, endocannabinoid therapy for cardiac channels, and PUFA effects on potassium channels. Awards/Grants: No specific honors or grants mentioned in available texts. Advising: No listed advisees found. His research group appears focused on collaborative projects involving multiple institutions. Labs/Teams: Active in the Division of Cell and Neurobiology, part of a multidisciplinary environment studying cellular structure/function and sensory systems.

David G. Amaralمشاهده پروفایل

استاد

• Neurobiology
• Psychiatry
• Behavioral Neuroscience
• +۷ مورد دیگر

David G. Amaral is a Professor in the Department of Psychiatry and Behavioral Sciences at the University of California, Davis School of Medicine. He serves as the Director of Research at the UC Davis MIND Institute and holds the Beneto Foundation Chair, focusing on autism and neurodevelopmental disorders. His leadership roles include coordinating the Autism Phenome Project and directing Autism BrainNet, a collaborative postmortem brain tissue initiative. From 2015, he has been Editor-in-Chief of Autism Research , the journal of the International Society for Autism Research, and was appointed to the Interagency Autism Coordinating Committee in 2016. Education: B.A., Northwestern University (1968) Ph.D., Neuroscience/Psychology, University of Rochester (1977) Fellowship in Neuroanatomy, Washington University (1980) His research spans neurobiology, psychiatry, and behavioral neuroscience, with a focus on autism spectrum disorder (ASD). He investigates neurodevelopmental mechanisms, including cortical and amygdala connectivity, metabolomics, and primate models. His work also explores maternal immune activation (MIA) and its impact on neurodevelopment, as well as longitudinal brain growth patterns in ASD. Dr. Amaral has received prestigious awards, including the NARSAD Distinguished Investigator Award (2008), University of California Distinguished Professor (2009), and Fellowship in the American Association for the Advancement of Science (AAAS) (2009). He previously served as President of the International Society for Autism Research (2009). At the MIND Institute, he leads multidisciplinary teams studying autism through neuroimaging, genetics, and metabolomics. His recent publications emphasize cortical development, neurogenetics, and biomarker discovery in ASD.

Michael Millerمشاهده پروفایل

استاد

• Medical Imaging
• Computational Anatomy
• Pattern Theory
• +۳ مورد دیگر

Michael I. Miller is the Bessie Darling Massey Professor and director of the Department of Biomedical Engineering at Johns Hopkins University (JHU), where he also leads the Center for Imaging Science and co-directs the Kavli Neuroscience Discovery Institute. His work focuses on computational medicine, medical imaging, and computational anatomy, particularly in neurodegenerative diseases like Alzheimer’s, Huntington’s, and schizophrenia. Miller has pioneered cloud-based methods for brain image libraries and algorithms, co-founded four startups, and holds over 200 publications and two textbooks. He earned his BS from SUNY Stony Brook (1976) and MS/PhD from JHU (1978/1983). Education: Bachelor of Science, State University of New York at Stony Brook, 1976 Master of Science, Johns Hopkins University, 1978 Doctor of Philosophy, Johns Hopkins University, 1983 Research Interests: Miller’s research integrates advanced imaging technologies to study brain structure and function in health/disease. Key areas include: Functional and structural analysis of neurodegenerative diseases Development of computational tools for early disease detection Multiscale data integration (molecular to tissue) Translational applications in clinical diagnostics Awards: IEEE Biomedical Engineering Thesis Award (1982) Johns Hopkins Paul Ehrlich Thesis Award (1983) NSF Presidential Young Investigator Award (1986) Johns Hopkins Gilman Scholar (2011) Fellow, American Institute for Medical and Biological Engineering Labs/Teams: His lab at JHU develops cloud-based imaging tools and collaborates on translational research. Projects include the xIV-LDDMM Toolkit and STalign spatial transcriptomics alignment software.

Mark Goldmanمشاهده پروفایل

استاد

• Computational Neuroscience
• Neural Circuits
• Synaptic Plasticity
• +۴ مورد دیگر

Mark Goldman is a Professor in the Department of Neurobiology, Physiology and Behavior at the University of California, Davis. His research focuses on computational neuroscience, neuroengineering, and the study of neural circuits underlying memory, learning, and sensorimotor control. He is affiliated with the Center for Neuroscience and the Ophthalmology and Vision Science program. His work integrates mathematical modeling with experimental data to understand neural mechanisms in systems such as the cerebellum, oculomotor systems, and reinforcement learning circuits. Key research themes include synaptic plasticity rules, dynamics of neural circuits during memory consolidation, and the interplay between circuit architecture and adaptive behavior. Recent studies explore closed-loop systems, oscillatory mechanisms in short-term memory, and context-dependent neural control. His computational frameworks bridge theoretical neuroscience with experimental observations in both vertebrate and microbial systems. Goldman has contributed to education through innovative course-based research programs combining microbial biology with mathematical modeling. His publications reflect a deep engagement with interdisciplinary methods, including systems theory, machine learning, and biophysical modeling.

Justin Blauمشاهده پروفایل

استاد

• Behavioral genetics
• Neurobiology
• Circadian rhythms
• +۴ مورد دیگر

Justin Blau is a **Professor of Biology and Neural Science** at **New York University (NYU)**, affiliated with the **Faculty of Arts and Science** and the **Center for Neural Science**. He joined NYU in 2000 as an Assistant Professor, was promoted to Professor in 2013, and holds additional roles at the NYU Abu Dhabi Research Institute. His research focuses on **behavioral genetics, circadian rhythms, and neurobiology**, using Drosophila as a model system to study how genes control animal behavior and circadian timing mechanisms. Education: - 1996 Ph.D., Imperial Cancer Research Fund & London University - 1991 B.A., Cambridge University Research Highlights: - Investigates circadian clock neurons and their role in behavioral timing. - Developed techniques for studying gene expression in pacemaker neurons. - Explores neuronal plasticity and network dynamics in circadian systems. Teaching: - Courses include *Genes & Animal Behavior*, *The Art of Scientific Investigation*, and *Signaling in Biological Systems*. Awards: 2013 NYU Golden Dozen Teaching Award 2005 Eppendorf & Science Essay Prize Finalist 1999 Human Frontiers Science Program Fellowship Labs & Collaborations: - Organizes the NYU NeuroBiology SuperGroup and the NY Area Clock Group. - Collaborates with institutions like Rockefeller University and Columbia University.

Jeremy S. Dasenمشاهده پروفایل

استاد

• Molecular Neuroscience
• Developmental Genetics
• Behavioral Genetics
• +۵ مورد دیگر

Jeremy S. Dasen is a Professor in the Department of Neuroscience at NYU Grossman School of Medicine. His research focuses on understanding the genetic and molecular mechanisms underlying neural circuit assembly and motor behavior. He earned his PhD from the University of California, San Diego, and completed postdoctoral training in Neuroscience at Columbia University. Dr. Dasen's research interests include molecular neuroscience, developmental genetics, and the study of motor neuron diversity and connectivity. His lab employs multidisciplinary approaches, including genetic manipulations, genomic analysis, and behavioral assays to investigate how neural circuits are formed and regulated during development. Recent work highlights contributions to understanding evolutionary adaptations in locomotor systems, the role of epigenetic regulators like PRC1/PRC2, and molecular mechanisms governing spinocerebellar tract neuron diversity. His team has published extensively in top journals like Cell , Nature , and eLife . Notably, his research has uncovered genetic changes linked to tail-loss evolution in humans and apes, and identified key molecular pathways regulating motor neuron subtypes important for locomotor speed. The lab collaborates internationally, leveraging comparative vertebrate models to study neural circuit evolution. Dr. Dasen's work bridges developmental neurobiology and disease mechanisms, with implications for understanding neural circuit dysfunction in disorders affecting motor systems.