جست‌وجوی استاد و پژوهشگر

Michael J. Garabedianمشاهده پروفایل

استاد

• Nuclear Receptor Signaling
• Prostate Cancer Therapeutics
• Atherosclerosis
• +۵ مورد دیگر

Michael J. Garabedian is a Professor in the Departments of Microbiology and Urology at NYU Grossman School of Medicine. His research focuses on nuclear receptor signaling in disease contexts including prostate cancer, atherosclerosis, and stress-related disorders. He holds dual appointments and serves as Acting Vice Chair for Education in Microbiology. Education: PhD in Biochemistry from Brandeis University (advisor not specified), followed by a postdoctoral fellowship at University of California, San Francisco studying glucocorticoid receptor mechanisms. Joined NYU Langone in 1994 as an Assistant Professor, transitioning to full Professor and expanding into urology research. Research Interests: The lab employs cutting-edge approaches like CRISPR screens, single-cell RNA-seq, and spatial transcriptomics to study: Nuclear receptor regulation in macrophages and immune cells Novel prostate cancer therapies targeting androgen receptors LXRα signaling in metabolic/vascular diseases Glucocorticoid effects on neuronal function during stress Collaborates with Susan Logan's lab on peptoid-based drug development. Lab Structure: 4 main researchers including co-mentored MD/PhD students Sophie Ruff and Jeff Schneider. Maintains close ties with the Logan Lab through shared projects. Lab Location: Alexandria Center for Life Science - East Tower, Room 324. Active in training programs as Faculty Senate Representative.

• Neuroinflammation
• Alzheimer's Disease
• Neurodegenerative Diseases
• +۶ مورد دیگر

Sue Griffin is a Professor at the University of Arkansas for Medical Sciences , affiliated with the College of Medicine and the Department of Geriatrics . She holds secondary appointments in Neurobiology & Developmental Science, Pediatrics, Physiology and Cell Biology, and Psychiatry. Her research focuses on neuroinflammation, Alzheimer’s disease, and the role of apolipoprotein E (APOE) genotypes in neurodegenerative pathogenesis. NIH/National Institute on Aging R01AG084472 (2023–2028): Principal Investigator on neuroinflammation, protein aggregates, and autophagy rescue NIH R01HD037989 (2000–2007): Principal Investigator on cytokines in neurodegeneration and Down's syndrome NIH P01AG012411 (1995–2021): Principal Investigator on early events in Alzheimer pathogenesis Her work spans interdisciplinary fields including neuroimmunology, protein homeostasis, and cytokine signaling. Publications highlight connections between inflammation (e.g., IL-1β), amyloid pathology, and genetic risk factors like APOE4. She has contributed to understanding neuroinflammatory mechanisms in Alzheimer’s, Parkinson’s, and Down’s syndrome. Griffin’s recent articles focus on therapeutic strategies targeting autophagy, neuroinflammatory signaling in glioblastoma, and microbial contributions to Alzheimer’s neuropathology. Her research has been supported by NIH grants for over three decades, with collaborations across neurology, genetics, and pharmacology. She is affiliated with the Institute on Aging and the Center for Translational Neuroscience . Her work has been cited in over 50 scientific concepts, including Alzheimer Disease, Epilepsy, and Apolipoproteins E.

• Biophysics
• Computational Cell Biology
• Mesoscale Simulations
• +۳ مورد دیگر

Julian Charles Shillcock is a Lecturer and computational modeling specialist at École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the School of Life Sciences and the Lashuel Lab. He also serves as a Scientist in the UPDALPE group (Prof. Dal Peraro Group) and teaches in EPFL’s SSV (Teaching) and EDNE (Doctoral Education) sections. His work bridges biophysics, computational modeling, and cellular dynamics. PhD in Physics from Simon Fraser University (1996) Group Leader at Max Planck Institute of Colloids and Interfaces (2000-2005) Associate Professor at University of Southern Denmark (2005-2011) Blue Brain Project member since 2011 Shillcock’s research focuses on biomolecular condensates , membrane dynamics , and computational cell biology . He develops mesoscale simulation methods like Dissipative Particle Dynamics to study vesicle fusion , neuronal morphology , and neurodegenerative disease mechanisms . Recent work includes POETS computing platforms for accelerating simulations and Shiga toxin clustering on membranes. His publications (2022-2024) reveal trends in soft matter physics , computational neuroscience , and biomolecular condensate structure . Key collaborations include Imperial College London and University of Southampton on the POETS project. Scientific recognition includes: 2021 Polysphère prize for Best Teacher in Life Sciences He has advised PhD student Lida Kanari in computational morphology and contributed to neocortical microcircuit reconstruction . His research spans computational biophysics , toxin entry mechanisms , and novel computational platforms for life sciences education.

• Molecular Biology
• Biochemistry
• Genetics
• +۲ مورد دیگر

Kyle Jay is a Visiting Assistant Professor of Biology at the W.M. Keck Science Center , affiliated with Claremont Colleges. His research focuses on molecular mechanisms of telomere maintenance, DNA damage response, and RNA editing in neuronal systems. Educational Background : Bachelor of Science in Biochemistry, Brown University Ph.D. in Biochemistry and Molecular Biology, UCSF Jay's research explores how telomerase activity affects aging and genomic stability, as well as RNA editing dynamics in Drosophila. His recent work includes studies on DNA replication stress, telomere biology, and RNA-editing substrates in neural tissue. Notable publication trends include investigations into: Yeast aging models (2015-2016) RNA editing variability (2011) dNTP pool regulation ADAR enzyme function Genomic instability pathways

• Neuroplasticity
• Central Nervous System (CNS) Damage and Repair
• Computational Neuroscience
• +۵ مورد دیگر

Professor Ioanna Sandvig is a leading academic at the Norwegian University of Science and Technology (NTNU) , where she serves as group leader of the Integrative Neuroscience Group within the Department of Neuromedicine and Movement Science. She is also President of the Norwegian Neuroscience Society (NNS) and actively participates in international societies including the Federation of European Neuroscience Societies (FENS), Society for Neuroscience (SfN), ALBA Network, and Clinical-Academic Group for Alzheimer's Disease. Research Interests : Her group investigates neuroplasticity mechanisms in CNS damage and repair , focusing on structure-function relationships in biological neural networks under healthy and pathological conditions. They integrate in vivo , in vitro , and computational models to identify adaptive/maladaptive plasticity in neurodegenerative diseases like ALS and Alzheimer's. The research combines connectomics , transcriptional analysis , and geometric network modeling to decode network behaviors. Scientific Contributions : Recent publications explore topics including synaptic transcript dysregulation in ALS, functional complexity of 3D-engineered networks, and platinum microelectrode technologies. Her work demonstrates interdisciplinary approaches bridging neuroscience , bioengineering , and computational systems . Scientific Recognition : President, Norwegian Neuroscience Society (2024) Member, Federation of European Neuroscience Societies Member, Society for Neuroscience Member, ALBA Network Member, Clinical-Academic Group for Alzheimer's Disease Laboratory & Collaborations : The Integrative Neuroscience Group collaborates across NTNU's neuroscience departments and clinical institutions, developing tools for neuroplasticity analysis and contributing to preclinical disease modeling.

Michael Brandsمشاهده پروفایل

استاد

• Cardiovascular physiology
• Renal physiology
• Hypertension
• +۵ مورد دیگر

Michael Brands serves as Vice Dean and Professor of Physiology at Augusta University's Medical College of Georgia, holding a Regents' Professorship with active appointments in both the Department of Physiology and The Graduate School. His dual administrative and academic roles include curriculum leadership in medical education. Education: Ph.D. in Physiology, University of Missouri - Columbia (1988) B.S. in Biology, Rockhurst University (1983) Research Focus: Dr. Brands investigates cardiovascular-renal integrative physiology with emphasis on hypertension mechanisms. His seminal work demonstrates insulin's chronic sodium-retaining action and proves that natriuresis in uncontrolled Type I diabetes stems from insulin deficiency rather than hyperglycemia. Current studies explore sex-specific immune regulation of blood pressure using rodent models. Publication Trends: Recent work (2020-2023) reveals critical immune-hypertension interactions, particularly how T-regulatory cells mediate sex differences in blood pressure control. His research consistently employs translational models examining renal mechanisms in hypertension development, with growing focus on developmental origins of cardiovascular disease. Awards: Institutional Service Award (2020) Four consecutive Exemplary Teaching Awards (2013-2017) Service & Leadership: Dr. Brands chairs the Animal Care and Use Leadership Committee while directing MCG's Cardiopulmonary Module. His extensive editorial service includes 30+ years on the American Journal of Physiology board and NIH fellowship reviews, reflecting significant contributions to hypertension research infrastructure.

Martin A. Vinckمشاهده پروفایل

استاد

• Computational Neuroscience
• Systems Neuroscience
• Neural Coding
• +۱۰ مورد دیگر

Prof. Dr. Martin Vinck is a Professor at the Donders Centre for Neuroscience in the Department of Neurophysics , Radboud University. He is also a Research Group Leader at the Ernst Strüngmann Institute for Neuroscience and a faculty member at the International Max Planck Research School for Neural Circuits . Current affiliations: Radboud University, ESI Frankfurt, Max Planck Research School Positions: Professor, Research Group Leader, Review Editor for eLife Research Interests span computational and systems neuroscience, focusing on predictive processing in biological and artificial neural networks. His lab investigates: How distinct excitatory/inhibitory neurons regulate plasticity and flexible information processing Neural ensemble coding via spatio-temporal patterns and spike sequences Self-supervised learning mechanisms using spatial/temporal predictions Gamma oscillations, synchronization, and their role in visual encoding Scientific Contributions include developing algorithms for high-dimensional neural data analysis, co-supervising key studies on interneuron dynamics, and pioneering work on predictive coding in V1. His grants include the ERC Starting Grant (2019) and VIDI Grant (2024) . Lab Members include PhD students Jinke Liu, Jahan Esfandiarii, Athanasia Tzanou and alumni Irene Onorato, Marius Schneider, Ana Clara Silveira Broggini . He actively promotes open science , develops the Spike Toolbox , and reviews for journals like Neuron, eLife, PLoS Computational Biology .

Henri Tiedgeمشاهده پروفایل

استاد

• RNA Biology
• Neurobiology
• Translational Regulation
• +۵ مورد دیگر

Henri Tiedge, PhD , is a Professor at the Department of Physiology and Pharmacology within SUNY Downstate Medical Center . His research focuses on regulatory brain cytoplasmic (BC) RNAs , particularly their role in translational control mechanisms at neuronal synapses and their implications in neurological disorders and tumor biology . Institutional Affiliation: SUNY Downstate Medical Center (College of Medicine, Physiology and Pharmacology) Academic Rank: Professor Research Domains: RNA Biology, Synaptic Plasticity, Neurodegeneration, Oncology Dr. Tiedge investigates how BC1 and BC200 RNAs regulate local protein synthesis in dendrites through interactions with eukaryotic initiation factors (eIF4A/B) . His work demonstrates that BC RNA dysregulation leads to neuronal hyperexcitability , epileptogenesis , and cognitive dysfunction , with therapeutic applications in neuropsychiatric lupus using RNA decoys. He also explores BC RNA expression in germ cells and tumors , aiming to develop diagnostic/prognostic tools for cancer. Key publications include studies on RNA transport via hnRNP A2 and Purα , autoantibody-induced RNA displacement , and cross-talk between BC RNAs and FMRP in fragile X syndrome. His work has been supported by NIH grants NS046769 and DA026110 .

R. Michael Burgerمشاهده پروفایل

استاد

• Auditory Neuroscience
• Neural Circuitry
• Synaptic Physiology
• +۳ مورد دیگر

R. Michael Burger is a Professor in the Department of Biological Sciences at Lehigh University and serves as the Associate Dean for Research and Graduate Programs in the College of Arts and Sciences. His research focuses on auditory neuroscience, particularly how the brain processes sensory information through precise neural circuits. Education Ph.D. in Zoology (Neurobiology) from the University of Texas at Austin (2000) B.A. in Psychology and Anthropology from Ithaca College (1993) Dr. Burger's research investigates cellular, synaptic, and systems-level integration in auditory processing, with NIH-funded projects on sound localization and cholinergic modulation. He has edited books on neuromodulatory functions and serves on editorial boards of leading journals. Recent publications highlight his work on dopamine and cholinergic influences in auditory pathways, developmental synaptic plasticity, and computational auditory neuroscience. Grants include NIH R01 and R15 awards. Scientific Awards Fellow, Alexander von Humboldt Foundation Dr. Burger teaches behavioral neuroscience courses and contributes to graduate committee work, otolaryngology research, and grant review panels. He co-developed the HearMyCl app for cochlear implant simulations with Susan Perry and Brook Sawyer.

Russell Carrمشاهده پروفایل

استاد

• Toxicology
• Neurotoxicology
• Environmental Health
• +۳ مورد دیگر

Russell Carr , PhD, is a Professor at Mississippi State University's College of Veterinary Medicine. Holding a PhD in Animal Physiology (MSU, 1994) and MS in Biological Sciences (MSU, 1990), he focuses on neurotoxicology, pesticide mechanisms, and endocannabinoid system interactions. His career spans 30+ years studying organophosphate effects on neurotransmitter systems across developmental stages. Key Research Areas: Organophosphate pesticide neurotoxicity Endocannabinoid system disruption Developmental neurochemical impacts Cross-species enzyme inhibition Recent Publications (2023-2021) reveal trends in nanochannel CBD delivery systems, chlorpyrifos-induced proteomic changes in amygdala, and multi-omics approaches to pesticide-immune interactions. Earlier works establish foundational knowledge on cholinesterase inhibition kinetics and age-dependent toxicity profiles. Notable Contributions: Elucidated mechanisms of endocannabinoid enzyme inhibition by pesticides, demonstrated neurochemical impacts of low-dose exposures, and developed comparative models across species (rodents, fish).

Jeffrey M. Chungمشاهده پروفایل

دانشیار

• Epilepsy
• Neural Signal Processing
• Neurosurgery
• +۴ مورد دیگر

Jeffrey M. Chung, MD, FAAN is an Associate Professor of Neurology at Cedars-Sinai Medical Center. He serves as Director of both the Epilepsy Program and the Neurophysiology Laboratory since 2013. His clinical practice focuses on epilepsy and neurophysiology, with 26 years of experience in neurology and clinical neurophysiology. Northwestern University Medical School (1999) - MD Evanston Hospital (2000) - Internship UCLA (2003) - Residency UCLA (2005) - Fellowship Dr. Chung's research explores epilepsy mechanisms, neural signal processing , multi-modal probabilistic mapping for surgical outcomes, and device-oriented therapies . His recent publications focus on theta phase precession in memory , single-neuron correlates of seizures , and neuroimaging in post-stroke conditions . He leads clinical trials on novel anti-seizure agents and neuromodulation techniques. Circle of Friends – Grateful Patient Donation Honoree (Cedars-Sinai) Southern California Super Doctors (Los Angeles Magazine) Falks Medical Scholar (Arthritis Foundation) Golden Apple Teaching Award (Cedars-Sinai) Dr. Chung directs the Epilepsy Program and Neurophysiology Laboratory at Cedars-Sinai, while also mentoring through journal clubs and clinical teaching. He has received multiple industry grants from companies like Marinus Pharmaceuticals and Vertex Pharmaceuticals for trials on treatment-resistant epilepsy. His work bridges clinical care with neurophysiological research and advanced neural signal processing .

• Molecular Biology
• Biochemistry
• Neurodegenerative Diseases
• +۱۰ مورد دیگر

Dr. Andrey L. Karamyshev is an Associate Professor at the School of Medicine, Texas Tech University Health Sciences Center, in the Department of Cell Biology & Biochemistry. His research focuses on molecular mechanisms of human diseases, particularly neurodegenerative disorders and cancer, through the lens of protein synthesis regulation and quality control. Academic Rank: Associate Professor Research Affiliation: Institute for One Health Innovation Research Interests include: Molecular mechanisms of translational regulation RNA and protein quality control Protein interactions in health and disease Signal Recognition Particle (SRP) dysfunction in neurodegenerative diseases Role of AGO2 in mRNA degradation Co-translational protein folding and targeting Recent Publications highlight his work on the RAPP pathway, SRP interactions in Leishmania, and protein misfolding in Parkinson’s and Alzheimer’s diseases. His studies integrate in vivo and in vitro methodologies, including photo-crosslinking and iPINCH techniques. Scientific Awards & Recognition : Featured in Trends in Biochemical Sciences (2014) Highlighted in Nature Reviews Genetics (2014) Recommended by Faculty of 1000 (F1000Prime) for multiple publications Top 5.0% viewed/downloaded article in Frontiers (2018) Dr. Karamyshev welcomes graduate students to his lab, emphasizing collaboration and innovative research in molecular biology and biomedical sciences. His lab is affiliated with the Institute for One Health Innovation, fostering interdisciplinary approaches to human disease treatment.

Bhanu Jenaمشاهده پروفایل

استاد

• Molecular and cellular physiology
• porosomes
• exocytosis
• +۴ مورد دیگر

Bhanu Jena, Ph.D. (dr. hc. mult.) is the George E. Palade University Professor & Distinguished Professor at Wayne State University School of Medicine, Department of Physiology. He serves as Founder-Director of the Institute of NanoBioScience and maintains his laboratory at 5245 Scott Hall. As the only living University Professor and the second in Wayne State University's 160-year history, Dr. Jena holds one of the most prestigious academic appointments at the institution. Dr. Jena received his B.Sc. from BJB College in Orissa, India (1975), M.Sc. in Reproductive Endocrinology from Utkal University (1978), and Ph.D. in Reproductive Endocrinology from Iowa State University (1988). Following postdoctoral training at Iowa State and Yale Universities (1988-1994), he joined Yale University as an Assistant Professor before moving to Wayne State University in 2000 as a tenured full Professor. Dr. Jena's research centers on molecular and cellular physiology, with a groundbreaking focus on porosomes - the universal secretory machinery in cells that he discovered. His laboratory investigates how cells secrete, challenging traditional views of exocytosis. A second major research focus involves designing novel approaches, techniques, and instrumentation for biological problem-solving, including developing a force microscope capable of imaging intracellular structures at nanometer resolution in real-time. His recent publications reveal an evolving research trajectory spanning cellular secretion mechanisms, Alzheimer's disease therapeutic approaches, cystic fibrosis treatments, antiviral strategies against enveloped viruses, and advanced microscopy techniques. This multidisciplinary work bridges fundamental cell biology with clinical applications across neuroscience, respiratory diseases, and infectious disease. Elected Foreign Member of the Georgian National Academy of Science Fellow of the American Association for the Advancement of Science (AAAS) Swebelius Cancer Research Award Sir. Aaron Klug Award ASAS Basic Biological Science Award Ranbaxy Basic Research in Medical Sciences Award Elected Foreign Member of the Korea Academy of Science & Technology George E. Palade Gold Medal Six Honorary Doctorates With over 30 years of instructional experience, Dr. Jena teaches courses in cell biology, nanoscience/nanomedicine, physiology, endocrinology, and biochemistry. His lab receives primary funding from NIH and NSF grants. The Jena Lab continues to pioneer research on cellular nanomachines and their implications for human health, maintaining active collaborations across multiple disciplines while accepting new MS, PhD, and MD/PhD students into its research programs.

Tobias Bonhoefferمشاهده پروفایل

استاد

• Synaptic plasticity
• Learning and memory
• Activity-dependent development
• +۴ مورد دیگر

Prof. Dr. Tobias Bonhoeffer serves as Director and Head of the Department of Synapses – Circuits – Plasticity at the Max Planck Institute for Biological Intelligence in Munich, Germany. His research focuses on synaptic plasticity, learning and memory, and the structural and functional dynamics of the visual system and hippocampus. Institution: Max Planck Institute for Biological Intelligence Department: Synapses – Circuits – Plasticity Academic Rank: Professor Research Interests encompass cellular and systems neurobiology, with specialized investigations into: Synaptic plasticity mechanisms Structural changes in dendritic spines Experience-dependent cortical circuit formation Memory relearning efficiency Functional mapping in visual cortex Neural adaptation in behaving animals Publications demonstrate expertise in neuroscience, particularly synaptic biology and neural circuit dynamics, with notable contributions to understanding cortical plasticity and hippocampal function. His lab has trained students like Sandra Reinert and Matthew McCann through the GSN program.

• Neurodegenerative Diseases
• Transmissible Spongiform Encephalopathies
• Viral Pathogenesis
• +۴ مورد دیگر

Laura Manuelidis is Professor of Surgery (Neuropathology) and Section Chief of Neuropathology at Yale School of Medicine, where she directs the Manuelidis Laboratory focused on transmissible spongiform encephalopathies (TSEs). She holds secondary appointments in Virology and Surgery. Dr. Manuelidis earned her BA from Sarah Lawrence College (1963) and MD from Yale University (1967). Her research spans neurodegenerative diseases with emphasis on Creutzfeldt-Jakob Disease (CJD) and scrapie agents. Key contributions include: discovery of SPHINX DNA elements in mammalian brain cells; characterization of virus-like infectious particles; demonstration of blood-borne transmission routes; and challenge of the protein-only prion hypothesis through evidence of nucleic acid-dependent infectivity. Her current work explores prokaryotic DNA in neurodegeneration and innate immune responses to neuroinvasive agents. Analysis of her 15 most recent publications reveals consistent focus on: 1) Structural characterization of TSE infectious particles, 2) Role of nucleic acids in prion replication, 3) SPHINX DNA in synaptic function, 4) Novel decontamination methods, and 5) Neuronal responses to chronic infection. Her work integrates virology, molecular neurobiology, and proteomics. Honors include: Chromosoma Prize (1989) NIH Research Career Development Award (1974) Andrew W. Mellon Young Investigator Award (1974) Swibelius Award for Cancer Research (1970) She maintains continuous NIH R01 funding since 1970 and directs Yale's archival neuropathology repository (1951-1996). As FDA TSE advisory committee member, she contributes to blood safety policies. Her laboratory trains international researchers in neuropathological techniques and TSE biosafety protocols.