جست‌وجوی استاد و پژوهشگر

Mercedes Paredesمشاهده پروفایل

دانشیار

• Human Brain Development
• Neurogenesis
• Neural Stem Cells
• +۵ مورد دیگر

Mercedes Paredes is an Associate Professor in Residence in the Department of Neurology at the University of California, San Francisco School of Medicine. Her research focuses on understanding human brain development, with particular emphasis on neural stem cells, neurogenesis, and interneuron migration in the developing human brain. Dr. Paredes has established herself as a leading researcher in the field of developmental neurobiology through her extensive publication record in top-tier journals. Dr. Paredes' research interests span multiple critical areas of neuroscience including human brain development, cortical organization, neural stem cell biology, and the mechanisms underlying brain malformations. Her work has significantly advanced our understanding of how interneurons develop and migrate in the human brain, with important implications for neurological disorders. She employs cutting-edge techniques including single-cell analysis, multi-omic approaches, and advanced imaging to investigate the cellular and molecular mechanisms of human neurodevelopment. Analysis of Dr. Paredes' recent publications reveals a consistent focus on human-specific aspects of brain development. Her research demonstrates how human neural development differs from model organisms, particularly in the timing, organization, and molecular regulation of neurogenesis. She has made significant contributions to understanding the role of vascular cells in neural stem cell niches, the dynamics of interneuron development, and the molecular mechanisms underlying cortical malformations. Dr. Paredes has been actively involved in multiple collaborative research projects investigating the developing human brain. Her laboratory likely employs a multidisciplinary approach combining molecular biology, cellular neuroscience, and advanced imaging techniques to address fundamental questions about human brain development. While specific grant information isn't provided in the available text, her extensive publication record suggests successful funding from major research agencies.

• Human Developmental Biology
• Genomics
• Single-cell RNA Sequencing
• +۶ مورد دیگر

Dr. Steven Lisgo is a developmental biologist and genomics researcher affiliated with Newcastle University . His research focuses on human embryonic and fetal development, with a strong emphasis on using single-cell RNA sequencing and spatial transcriptomics to map cellular and molecular processes across organs such as the brain, heart, skin, liver, and immune system. Research Interests: Human developmental biology and embryogenesis Single-cell genomics and transcriptomics Neurodevelopment and cerebellar morphogenesis Immune system ontogeny and organogenesis Congenital malformations and genetic disorders Comparative developmental genomics across mammalian species His recent publications (2020–2025) reflect a consistent trend toward creating comprehensive cell atlases of developing human organs, integrating multi-omics approaches to understand gene expression, cellular identity, and developmental trajectories. These studies often involve large-scale collaborations and utilize resources like the Human Developmental Biology Resource (HDBR) . Scientific Contributions & Collaborations: Dr. Lisgo has co-authored numerous high-impact studies with collaborators such as Susan Lindsay , Rachel Botting , and Emily Stephenson , indicating his role in both research leadership and data generation. His work has contributed to understanding developmental disorders like holoprosencephaly, Down syndrome, and congenital heart defects. Labs & Resources: He is closely associated with the Human Developmental Biology Resource (HDBR) , a UK-based initiative that provides human embryonic and fetal tissues for research, and is likely involved in managing or utilizing this resource for his studies.

Stephen Van Hooserمشاهده پروفایل

دانشیار

• Neuroscience
• Visual Cortex
• Neural Circuits
• +۵ مورد دیگر

Stephen Van Hooser is an Associate Professor of Biology at Brandeis University, where he leads the Neural Circuits Lab. His research focuses on understanding how neural networks assemble during development and function in circuits to enable perception and behavior. He holds affiliations with multiple Brandeis programs including the Department of Biology, Neuroscience Graduate Program, Volen Center for Complex Systems, Sloan-Swartz Center for Theoretical Neurobiology, and Quantitative Biology Program. Dr. Van Hooser received his B.S. from the California Institute of Technology, his Ph.D. from Brandeis University, and completed postdoctoral training at Duke University Medical Center. His educational background bridges physics, biology, and neuroscience, providing a strong foundation for his interdisciplinary research approach. Dr. Van Hooser's research centers on two major themes: the role of experience in the development and maturation of neural circuits, and the operating principles of cortical circuits. His lab applies cutting-edge optical and optogenetic tools to observe both fine-scale circuit features and systems-level responses simultaneously in the living brain. By combining these approaches with advanced physiological and anatomical techniques, his team addresses previously inaccessible questions about neural circuitry in mammalian visual cortex. His work particularly investigates how motion selectivity develops in an experience-dependent manner, whether experience merely permits the completion of developmental programs or alters the trajectory of circuit construction, and which circuit elements are modified by experience. Analysis of his recent publications reveals a progression from basic circuit mechanisms to more complex behavioral correlates, with increasing use of mouse models alongside traditional ferret models, and growing interest in neurodevelopmental disorder models like Shank3 knockout mice. Beverly Patterson Bishop Award for Excellence in Neuroscience, Brandeis University, 2015 As a principal investigator, Dr. Van Hooser mentors graduate students and postdoctoral researchers in the Neural Circuits Lab. His research program has been consistently supported by major funding sources including the American Recovery and Reinvestment Act (ARRA), John Merck Foundation, Charles H. Hood Foundation, American Physiological Society, National Science Foundation, and National Institutes of Health. His lab has developed the Neuroscience Data Interface (NDI) to facilitate organization and sharing of neuroscience data, reflecting his commitment to open science and data transparency. The Neural Circuits Lab is equipped with advanced imaging and electrophysiology capabilities, including 2-photon microscopy for in vivo imaging of neural activity. The lab employs a multidisciplinary approach combining computational modeling, molecular techniques, and behavioral analysis to understand how neural circuits develop and function. Dr. Van Hooser's team collaborates with researchers across Brandeis and other institutions to advance our understanding of cortical circuit organization and plasticity, with a particular emphasis on the visual system as a model for understanding general principles of neural circuit function.

Mila van den Hurk-Roozenمشاهده پروفایل

پژوهشگر

• Behavioural Sciences
• Neurosciences
• Evolutionary Biology
• +۴ مورد دیگر

Dr. Mila van den Hurk-Roozen is a Researcher in the Faculty of Science and Engineering at the University of Groningen, affiliated with the Kas lab in Behavioral Neuroscience and the Groningen Institute for Evolutionary Life Sciences. Her work bridges evolutionary biology, neurosciences, and behavioral sciences, focusing on social complexity, genetic conservation, and psychiatric disorders. She holds a PhD from the University of Groningen (2024) and has contributed to interdisciplinary research on digital health, educational technology, and social brain dynamics. Research Interests: Her research explores markers of selection on social complexity in the human genome, evolutionary methodologies, and the interplay between genetics and social behavior. She also investigates applications of virtual reality in education and behavioral monitoring during pandemics. Lab/Affiliations: She is part of the Kas lab - Behavioural Neuroscience, collaborating on projects involving C. elegans genetics and psychiatric disorder studies. Her work has been published in Behavior Genetics , European Neuropsychopharmacology , and Computers & Education .

• Neuroscience
• Neurodevelopmental Disorders
• Brain Development
• +۴ مورد دیگر

Luis De La Torre-Ubieta is an Assistant Professor-in-Residence in the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine, University of California Los Angeles. He directs an active research laboratory established in 2018 that investigates mechanisms of human brain development and neurodevelopmental disorders using multidisciplinary approaches including single-cell genomics and stem cell models. His lab is affiliated with UCLA's Intellectual and Developmental Disabilities Research Center (IDDRC). Education: Ph.D. in Neurobiology, Harvard University (2010) B.S. in Biology, University of Puerto Rico (2003) Research Focus: Dr. De La Torre-Ubieta's research program centers on understanding the gene regulatory mechanisms governing human cortical development and their disruption in neuropsychiatric disorders. His laboratory employs cutting-edge genomic technologies including single-cell RNA sequencing, chromatin accessibility mapping, and brain organoid models to investigate: 1) Developmental trajectories of human neocortex formation; 2) Isoform diversity and post-transcriptional regulation during neurogenesis; 3) Genetic and epigenetic mechanisms underlying neurodevelopmental conditions; and 4) Evolutionary conservation of neuronal specification programs. Publication Trends: His extensive publication record demonstrates consistent focus on neurodevelopmental genomics, with recent work emphasizing single-cell resolution analyses of human brain development. Publications frequently integrate multi-omic approaches to map gene regulatory networks across developmental timepoints. Research consistently bridges basic mechanisms of cortical development with translational applications for neuropsychiatric disorders, particularly through identification of disease-relevant molecular pathways. Laboratory & Collaborations: The De La Torre-Ubieta Lab employs multidisciplinary approaches combining wet-lab experimentation with computational biology. The team collaborates extensively within UCLA's neuroscience research ecosystem and maintains national/international partnerships. Research has been published in high-impact journals including Science, Nature, Cell, and Neuron.

• Behavioral Neuroscience
• Systems Neuroscience
• Visual Processing
• +۳ مورد دیگر

Philip Parker is an Assistant Professor in the Department of Psychology at Rutgers University. His research focuses on understanding how neural circuits in the brain contribute to natural visual behaviors by integrating action and sensory processes. He employs ethological paradigms, high-density neural recordings, and optogenetic techniques to study visual processing in freely moving animals, aiming to bridge gaps in models of neurological disorders. His research emphasizes the interplay between sensory input and motor output, particularly in contexts resembling real-world conditions. Key themes include neural basis of spatial navigation, sensorimotor integration, and synaptic development. The lab promotes inclusivity and supports underrepresented groups in scientific careers. Recent work highlights advancements in understanding visual cortex dynamics, thalamostriatal synapse remodeling in Parkinsonian models, and the role of molecular factors like nectin-3 in synaptic formation. Research spans behavioral neuroscience, systems neuroscience, and translational approaches for neurodegenerative therapies.

James Noonanمشاهده پروفایل

استاد

• Human Evolutionary Genetics
• Neurodevelopment
• Gene Regulatory Networks
• +۵ مورد دیگر

James Noonan is the Albert E. Kent Professor of Genetics and Professor of Neuroscience at Yale University's School of Medicine. He serves as co-Director of Graduate Studies in Genetics and holds secondary appointments in Ecology & Evolutionary Biology and Neuroscience. His research focuses on understanding the genetic basis of human biological uniqueness, particularly through the study of gene regulatory changes in development and evolution. Education & Career: B.S. in Biology and English Literature (SUNY Binghamton, 1997) Ph.D. in Genetics (Stanford University, 2004) Postdoctoral Fellowship at Lawrence Berkeley National Laboratory (2004–2007) Joined Yale as Assistant Professor in 2007, promoted to Professor in 2021 Research Interests: Human-specific regulatory elements (HARs and HSGDs) in neurodevelopment and limb evolution Epigenomics of human brain evolution Functional genomics approaches to study gene regulation in development Evolutionary innovations in gene regulatory networks His lab pioneered the use of humanized mouse models and massively parallel assays to dissect how human-specific genetic changes drive developmental traits, such as limb morphology and cortical expansion. Key Contributions: Discovered that HARs act as enhancers critical for human-specific traits Identified human-specific enhancer activity in limb and brain development Developed methods to study regulatory elements in human embryonic tissues Awards: Edward J. Mallinckrodt Foundation Fellowship (2008) Academic Leadership: Founder of Yale's genomics training programs Advocate for diversity and inclusion in science Co-leads initiatives to integrate systems biology and evolutionary approaches in neuroscience Lab & Collaborations: The Noonan Lab collaborates with researchers in genomics, developmental biology, and computational sciences to advance understanding of human evolution and disease mechanisms.

Hemanth Mohanمشاهده پروفایل

استادیار

• Neuroscience
• Systems Neuroscience
• Neuroanatomy
• +۷ مورد دیگر

Hemanth Mohan, PhD, is an Assistant Professor at The University of Texas Health Science Center at Houston (UTHealth Houston). His research focuses on unraveling the neural circuit mechanisms underlying sensorimotor transformation through the Mohan Lab, which employs cutting-edge techniques in molecular and systems neuroscience, neuroanatomy, genetics, behavior analysis, machine learning, and AI. The lab investigates how cortical circuits integrate sensory inputs with cognitive information to generate goal-directed motor outputs. Key Research Themes: Sensorimotor integration, cortical circuit dynamics, neural coding, and computational modeling of behavior. Methodologies: Genetic and viral tools, widefield/two-photon imaging, electrophysiology, chemogenetics/optogenetics, and high-dimensional data analysis using AI/ML. Recent publications highlight his work on cortical projection neuron types, their role in functional subnetworks, and their contributions to decision-making and skilled motor behaviors. Collaborative studies span rodent and human models, emphasizing cross-species neural architecture comparisons. Selected Trends: Decoding cortical connectivity in sensorimotor control, modeling neural dynamics in awake behaving mice, and classifying projection-defined neuron types.

Sofie Nyströmمشاهده پروفایل

دانشیار

• Amyloid proteins
• Prion diseases
• Virus amyloids
• +۳ مورد دیگر

Sofie Nyström is an Associate Professor and Docent at Linköping University's Department of Physics, Chemistry and Biology (IFM), within the Chemistry (KEMI) division. Her research focuses on amyloid proteins, prion diseases, and the interplay between viral proteins and amyloid formation. She investigates structural heterogeneity of amyloids, viral amyloidogenesis, and their roles in neurodegenerative diseases like Alzheimer's. Key research areas include the molecular mechanisms of amyloid formation, strain-specific effects of prions, and the implications of amyloid polymorphism for diagnostics and treatments. Her work combines protein science tools, in vivo models, and advanced imaging techniques to study amyloid interactions and their pathological consequences. Collaborators include Per Hammarström and Peter Nilsson, with notable contributions to understanding SARS-CoV-2 spike protein amyloidogenesis linked to Long COVID symptoms. Current projects involve post-doctoral researchers like Debdeep Chatterjee and master students including Vilma Odland, Henrik Westman, and Ebba Hellstrand. Her lab, part of the Hammarström group, explores amyloid behavior in P3-level biosafety conditions, particularly for prion research. Recent studies highlight novel fluorescent probes for amyloid imaging and the role of viral amyloids in disease progression. Publications emphasize structural insights into amyloid deposits, cross-seeding mechanisms between proteins, and the development of diagnostic tools. Her work bridges fundamental biophysics with clinical applications, addressing urgent questions in neurology and infectious disease.

Katie Longمشاهده پروفایل

مدرس ارشد

• Neurodevelopment
• Extracellular Matrix Biology
• Cortical Folding
• +۳ مورد دیگر

Dr. Katie Long is a Senior Lecturer in Developmental Neurobiology at King's College London's Institute of Psychiatry, Psychology & Neuroscience (IoPPN). She is affiliated with the School of Neuroscience and the Centre for Developmental Neurobiology. Her research focuses on understanding how the extracellular matrix (ECM) influences human neocortex development, particularly the formation of cortical folds and the mechanisms underlying neurodevelopmental disorders. She holds grants from the BBSRC, Medical Research Foundation, and MRC, and leads projects investigating ECM's role in brain folding and SARS-CoV-2 effects on fetal brain development. Key affiliations: King's MechanoBiology Centre (KMBC), Autism spectrum disorder Building Recent grants: £14m for fetal brain studies post-pandemic, BBSRC grant on neuronal activity in brain development Research interests include ECM components like HAPLN1, lumican, and collagen I, their interaction with hyaluronic acid (HA), and signaling via CD168/ERK pathways. Her work bridges developmental biology and regenerative medicine, with focus on mechanobiology principles. Publications emphasize ECM's role in cortical folding, SARS-CoV-2 neurodevelopmental impacts, and microglial contributions to neurodevelopmental disorders. Awards include the 2024 Medical Research Foundation Changing Policy and Practice Award for disseminating fetal development research.

• Epilepsy
• Neurology
• Signal Processing
• +۷ مورد دیگر

Dr. Wim Van Drongelen is a Professor at the University of Chicago in the Department of Pediatrics-Neurology. His research focuses on understanding the mechanisms underlying epilepsy through interdisciplinary approaches including advanced statistical and digital signal processing, non-linear dynamics, and modeling. His lab employs mathematical modeling, computational simulations, animal models, patient tissue analysis, and clinical recordings to improve epilepsy treatment.

Brian Theyelمشاهده پروفایل

استادیار

• cellular neuroscience
• Neural circuits
• neuromodulation
• +۵ مورد دیگر

Brian Theyel, M.D., Ph.D. is an Assistant Professor of Psychiatry and Human Behavior at Brown University's Warren Alpert Medical School. His primary academic appointment is in the Department of Psychiatry and Human Behavior, where he conducts research on the cellular mechanisms underlying neuropsychiatric disorders and provides clinical services in the psychiatric emergency room at Butler Hospital. Dr. Theyel earned both his MD and PhD from the University of Chicago in 2012, completing a rigorous dual-degree program that prepared him for his career as a physician-scientist. His educational background reflects a strong foundation in both clinical medicine and basic neuroscience research. Dr. Theyel's research centers on understanding how unique properties of interneurons relate to neuropsychiatric disease, with a particular focus on how inhibitory interneurons regulate brain activity. His laboratory employs advanced techniques including whole-cell patch-clamp recording, local field potential measurements, in vitro neuroimaging, cell-specific gene knockout strategies, and sophisticated neuroanatomical methods. His most significant discovery involves how a specific inhibitory interneuron puts 'the brakes' on brain activity by firing repeatedly in the 'backward' direction during periods of elevated neural activity. Analysis of Dr. Theyel's publication record reveals a consistent focus on neural circuit mechanisms, particularly examining ectopic action potentials in interneurons and their implications for neuropsychiatric disorders. His work bridges basic neuroscience with clinical psychiatry, exploring how cellular and microcircuit dysfunctions contribute to conditions like epilepsy and other neurological disorders. Recent publications show an increasing emphasis on neurodevelopmental disorders and the application of circuit-based approaches to understanding psychiatric disease. Brown University General Psychiatry Residency Education Committee Award (2021) Excellence in Triple Board Training Award - Brown University (2021) Psychiatry Research Mentoring Award – Brown University (2019) Martin Keller Outstanding Resident Award (2016) Chief Resident, Brown University Psychiatry Residency Training Program (2015-2016) Brown Mind-Brain Research day Poster award – 2nd place among residents/fellows (2015) NIMH Outstanding Resident Award (ORAP) (2014) Dr. Theyel is actively involved in teaching and mentoring, supervising residents in the Residency Continuity Clinic and teaching courses including a longitudinal seminar series on 'Evidence-Based Medicine' for psychiatry residents. He co-directs the Brain & Behavior course for first-year medical students at Brown. His research is supported by multiple prestigious funding sources including the Brown Department of Psychiatry and Human Behavior, NINDS, the Norman Prince Neurosciences Institute, the Carney Foundation, and the Simons Foundation. His collaborative network includes prominent researchers in neuroscience, particularly Barry Connors with whom he has published multiple papers. Dr. Theyel maintains an active laboratory dedicated to determining the underpinnings of neuropsychiatric disease at the cellular and microcircuit levels, with the goal of uncovering potential novel treatment targets. His work bridges the gap between basic neuroscience and clinical psychiatry, making significant contributions to understanding how neural circuit dysfunctions contribute to psychiatric disorders.

Giuliana Caronia-Brownمشاهده پروفایل

استادیار

• Neuroscience
• Molecular Neuroscience
• Developmental Neuroscience
• +۴ مورد دیگر

Giuliana Caronia-Brown is a Research Assistant Professor in the Department of Pharmacology at the Feinberg School of Medicine, Northwestern University, focusing on microRNA mechanisms in central and peripheral nervous system development. Her work centers on Wnt/BMP pathway regulation in hippocampus development (CNS) and dopamine neuron formation (PNS), with direct implications for Parkinson's Disease research. She is affiliated with the Northwestern University Clinical and Translational Sciences Institute (NUCATS). Education: PhD, University of London, England (2002) Postdoctoral Fellow in Neurobiology, Unknown Institution (2004) Postdoctoral Fellow in Neurobiology, University of Chicago (2007) Her research integrates molecular neuroscience and developmental biology to dissect neural patterning mechanisms: microRNA regulation of embryonic brain development Dopaminergic neuron subtype specification Wnt signaling in cortical/hippocampal formation Molecular vulnerability in Parkinson's Disease Analysis of her 2014-2021 publications reveals a cohesive trajectory investigating molecular determinants of neural development, particularly dopamine neuron diversity and cortical patterning. Her work employs intersectional genetics and molecular profiling to map embryonic origins of neuron subtypes, with consistent emphasis on Wnt pathway effectors and microRNA-mediated regulation. Recent studies directly link these mechanisms to Parkinson's Disease vulnerability. Information regarding student advising and research grants was not provided in available materials. Dr. Caronia-Brown operates within collaborative neuroscience networks centered at NUCATS, with publication records indicating sustained partnerships in dopaminergic neuron research and developmental neurobiology across multiple institutions.

• Neurophysiology
• Sensory neocortical networks

Dr. Harvey Swadlow is a Professor in the Department of Psychological Sciences at the University of Connecticut. His primary research investigates neurophysiological mechanisms underlying sensory processing in the neocortex, with special focus on thalamocortical interactions and cortical network dynamics. Professor Swadlow's research examines thalamocortical communication pathways, cortical layer-specific processing, and state-dependent modulation of sensory systems. His work utilizes advanced in vivo electrophysiological techniques to study awake behaving models, particularly focusing on visual thalamocortical circuits and cortical inhibitory networks. Publications consistently explore thalamocortical interactions across behavioral states, cortical microcircuit organization, and sensory processing mechanisms. His research employs techniques including multi-site extracellular recording, cortical laminar analysis, and in vivo characterization of synaptic transmission dynamics.

• Neuroscience
• Psychiatry
• Neural Circuitry
• +۳ مورد دیگر

Dr. Alicia Y Che is an Assistant Professor of Psychiatry at Yale University's School of Medicine, affiliated with the Department of Psychiatry and the Center for Brain & Mind Health. She joined Yale in 2021 after postdoctoral training at Weill Cornell Medical College and NYU. Her research focuses on neural circuits underlying social behavior and psychiatric disorders like PTSD. She holds a PhD in Physiology and Neurobiology from the University of Connecticut (2014) and a BS in Biology, Physics, and Physical Chemistry from Pacific Lutheran University (2009). Her key research projects explore oxytocin's role in social touch development and circuit dysfunction in PTSD. She investigates how sensory experiences shape cortical circuits using advanced techniques like in vivo calcium imaging and genetic manipulation. Dr. Che leads the Che Lab, which integrates molecular, electrophysiological, and behavioral approaches to study neural circuitry. Awards: NARSAD Young Investigator Award (2020), K99/R00 Pathway to Independence Award (2019). Labs/Teams: Director of Graduate Admissions for the Interdepartmental Neuroscience Program, member of the Janeway Society and Wu Tsai Institute. Her work bridges developmental neurobiology and translational psychiatry, emphasizing circuit-level mechanisms in mental health disorders.