جست‌وجوی استاد و پژوهشگر

• Immunology
• Microbiology
• Cancer Immunology
• +۴ مورد دیگر

Sara E Hamilton Hart is an Associate Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota, with leadership roles in Microbiology and Cancer Immunology. Her research focuses on immune responses to pathogens, vaccine development, and aging-related immune dysregulation. Key Affiliations: University of Minnesota, Hennepin Healthcare Research Institute, NIH National Institute of Allergy and Infectious Diseases, NIH National Institute of Child Health and Human Development Research Interests: Dr. Hart's work spans immunology, microbiology, and vaccinology. She investigates: Therapeutic applications of IL-15 in malaria vaccines Immune responses in preclinical mouse models, including 'dirty' mice Senescent cell effects on pathogen control Fetal immune system development influenced by maternal microbial exposure CRISPR/Cas9-based NK cell engineering for enhanced immunity Recent Publications: Her 15 most recent articles show a focus on T/B cell responses in malaria, NK cell dysfunction, immune aging, and vaccine strategies using cytokine modulation. Key themes include IL-15's role in antibody production, KLRG1+ T cell plasticity, and maternal-fetal immune interactions. Labs & Collaborations: Dr. Hart leads research at the Center for Immunology and collaborates with NIH-funded teams on Plasmodium and SARS-CoV-2 studies. Her projects often involve translational approaches bridging basic immunology and clinical applications.

Kristian Pietrasمشاهده پروفایل

استاد

• Cancer Research
• Tumor Microenvironment
• Targeted Therapy
• +۴ مورد دیگر

Kristian Pietras is a Professor and Principal Investigator at the Lund University Cancer Centre (LUCC) , affiliated with the Division of Translational Cancer Research at Lund University. He serves as a Research Team Manager and Principal Investigator in Experimental Oncology, focusing on the tumor microenvironment's role in cancer progression.

• Immunology
• Parasitology
• Microbiology
• +۳ مورد دیگر

Irah King is a Professor at the Department of Microbiology and Immunology , Faculty of Medicine and Health Sciences, McGill University , and a Senior Scientist at the RI-MUHC (Glen site) within the Translational Research in Respiratory Diseases Program and the Centre for Translational Biology . Her work focuses on understanding immune cell communication in barrier tissues like the intestine, lung, and skin, particularly in the context of Protective immune responses Chronic inflammatory disorders Microbiota-immune system interactions .

• Fungal Infections
• Pneumonia
• Sepsis
• +۲ مورد دیگر

Salman Qureshi is an Associate Professor in the Department of Medicine at McGill University , with a focus on innate immunity and fungal infections . He serves as a Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) , contributing to the Translational Research in Respiratory Diseases Program and the Centre for Translational Biology . His research interests center on identifying molecular mechanisms in innate immunity that protect against respiratory and systemic infections , particularly Cryptococcus neoformans and Aspergillus fumigatus . He utilizes mouse models and genetic approaches to study host susceptibility factors and their immunological pathways, with applications in critically ill patients . Among 15 recent publications , his work spans fungal infections (2025), neutrophil function (2021), resistance and tolerance to infections (2019), TLR2 activation in cancer metastasis (2017), and mTOR inhibition in lung injury (2012). His scientific contributions remain unlisted in terms of awards.

T. Hugh Jonesمشاهده پروفایل

استاد

• Testosterone Deficiency
• Diabetes
• Endocrinology
• +۴ مورد دیگر

Professor T. Hugh Jones is an Honorary Professor of Andrology at the School of Medicine and Population Health, University of Sheffield, and serves as a Consultant Physician in Diabetes and Endocrinology at Barnsley Hospital NHS Trust and as an Honorary Consultant Endocrinologist at the Royal Hallamshire Hospital in Sheffield. With over four decades of clinical and research experience, Professor Jones is recognized as a world leader in the field of testosterone deficiency research, particularly regarding its role in heart disease and diabetes pathogenesis. Professor Jones completed his Biochemistry BSc(Hons) from 1972-1975 and his medical degree from 1975-1980 at Sheffield University. He attained MRCP(UK) in 1984 and served as a Clinical Research Fellow in the Department of Human Metabolism and Biochemistry from 1985-1988 before becoming a Lecturer in Medicine at the University of Sheffield from 1988-1993. His clinical career includes service as a Consultant Physician with special interest in Diabetes and Endocrinology at the Royal Hallamshire Hospital from 1984-1998 and at Barnsley Hospital from 1998 to the present. Professor Jones's research has made significant contributions to understanding testosterone's role in metabolic health, being first to demonstrate that testosterone reduces insulin resistance, improves glycemic control (HbA1c), and quality of life in men with type 2 diabetes and hypogonadism. His work identified that 40% of men with Type 2 Diabetes have symptomatic testosterone deficiency. His recent publications focus on testosterone replacement therapy's effects on cardiovascular risk, bone health, inflammatory markers, and glycemic control in hypogonadal men with diabetes. His research demonstrates consistent themes of testosterone's cardioprotective effects, anti-inflammatory properties, and metabolic benefits. President of the Androgen Society (International) 2021-2023 Vice President of Androgen Society 2019-2021 Treasurer of Androgen Society 2017-2019 Chair Academic Sub-committee Association of British Clinical Diabetologists 2014-2020 Guideline committee Member for European Association of Urology 2015-2024 Guideline Committee Member British Society for Sexual Medicine 2017-2023 Professor Jones has led numerous clinical trials including the TIMES2 study on testosterone replacement in hypogonadal men with metabolic syndrome and diabetes, and the STRIDE study on testosterone therapy in hypogonadal men with uncontrolled type 2 diabetes. He has served as Training Programme Director for SpR's in Diabetes and Endocrinology in South Yorkshire (1999-2010) and chaired specialist education committees for diabetes and endocrinology training. His laboratory work has investigated testosterone's mechanisms of action on vascular function, inflammation, and metabolic pathways using both clinical studies and animal models.

Andrew Murphyمشاهده پروفایل

استاد

• Haematopoiesis
• Leukocyte Biology
• Atherosclerosis
• +۵ مورد دیگر

Professor Andrew Murphy is a leading academic at the Baker Heart and Diabetes Institute , where he serves as an NHMRC Investigator and CSL Centenary Fellow . He holds an honorary appointment in the Baker Department of Cardiometabolic Health and the Department of Medicine at The University of Melbourne . Murphy has made significant contributions to understanding how immune system dysfunction drives cardiovascular and metabolic diseases. BSc(Hons) in Biotechnology, Queensland University of Technology PhD in Medicine, Monash University His research focuses on haematopoiesis , immunometabolism , and inflammatory disease , with particular emphasis on: Multi-organ communication in haematopoiesis Hyperglycemic spikes in diabetes Inflammatory diseases impairing atherosclerosis regression Human monocyte subsets in cardiovascular disease Role of ether lipids in immune cell function Professor Murphy's recent publications analyze: Interferon signaling in trained immunity (2025) Novel oxysterols for atherosclerosis treatment (2024) Epigenetic regulation of cytokines in arthritis (2023) Extracellular vesicles in HIV-related inflammation (2022) His scientific accolades include: NHMRC Investigator Fellowship CSL Centenary Fellowship NHMRC Career Development Fellowship Sir Laurence Muir Medal (2015) He has supervised numerous students including Patrick Bell , Simon Xu , and Sara Zarifian . Murphy leads the Inflammation and Immunometabolism Program , which investigates six core laboratories focused on cardiovascular immunology.

Barbara Rita Alevriadouمشاهده پروفایل

استاد

• Cardiopulmonary physiology
• Cardiovascular Disease
• Metabolism
• +۱۲ مورد دیگر

Barbara Rita Alevriadou is a SUNY Empire Innovation Professor in the Department of Biomedical Engineering at the University at Buffalo – The State University of New York , with an adjunct appointment in the Department of Chemical and Biological Engineering . Her research bridges cardiovascular physiology , molecular signaling , and mitochondrial function to understand vascular dysfunction in diseases like atherosclerosis and diabetes. Education: PhD, Chemical Engineering, Bioengineering & Biosciences Institute, Rice University (1992) BS, Chemical Engineering, Aristotle University (1986) Research Interests: Vascular mechanobiology and endothelial mechanotransduction Calcium and reactive oxygen species signaling Mitochondrial function in cardiovascular disease Signal transduction in ischemia-reperfusion injury Publications Trends: Focus on mitochondrial Ca²⁺ uniporter dynamics Role of shear stress in vascular repair and disease Interplay between reactive oxygen species and apoptosis Computational modeling of endothelial responses Monocyte adhesion mechanisms in myocardial infarction Redox regulation in vascular mechanotransduction Scientific Awards: BMES Fellow (2024) American Physiological Society STAR Reviewer (2016) Certificate of Recognition, SfRBM (2016) Board of Directors, BMES (2014–2017) Welch Foundation Graduate Fellowship (1992) Grants: NIH/NHLBI R01 HL142673 (2018–2022): $1.82M AHA Grant-In-Aid (2016–2018): $154K NIH/NHLBI R21 HL106392 (2011–2013): $423K NIH/NHLBI R21 HL091417 (2008–2009): $410K NIH/NHLBI R01 HL067027 (2001–2006): $1.25M Laboratory: Director, Alevriadou Vascular Mechanobiology Laboratory (AVML) Focus: molecular mechanisms of endothelial dysfunction in cardiovascular disease

• Lipid Metabolism
• Cholesterol Homeostasis
• Nuclear Receptors
• +۵ مورد دیگر

Peter Tontonoz is a Professor at the University of California Los Angeles, jointly appointed in the Department of Pathology and Laboratory Medicine and the Department of Biological Chemistry. His research integrates molecular biology, metabolism, and immunology to study lipid homeostasis, nuclear receptor signaling (LXRs/PPARs), and metabolic diseases. With over 350 publications, he leads pioneering work on cholesterol transport, adipocyte biology, and atherosclerosis. His research focuses on: Regulation of cholesterol flux via nonvesicular transport pathways (e.g., Aster proteins) Transcriptional control of lipid metabolism by LXRs and PPARs Adipocyte differentiation and thermogenic programming Inflammatory mechanisms linking lipid disorders to atherosclerosis Recent articles (2022–2025) emphasize membrane lipid remodeling, organelle interactions, and sex-specific metabolic regulation. Key trends include: Mechanistic studies on phospholipid-protein interactions in mitochondria/ER Cholesterol-driven inflammation in vascular and neurological contexts PPAR isoform-specific roles in liver/adipose tissue adaptation

Kuka Mirelaمشاهده پروفایل

دانشیار

• Immunology
• Virology
• Cancer Biology
• +۵ مورد دیگر

Kuka Mirela is an Associate Professor of Pathology at Vita-Salute San Raffaele University and a tenure-track Project Leader in the Division of Immunology, Transplantation and Infectious Diseases (DITID) at the San Raffaele Scientific Institute in Milan. She holds a PhD from the University of Siena/Novartis Vaccines and completed postdoctoral training at the NIH (USA) and San Raffaele Scientific Institute. Her research focuses on immune responses to viral infections, B/T cell interactions, and tumor immunology. Research interests include: (1) Regulation of B cell responses by T cells and innate immune cells during viral infections, (2) Role of inflammatory monocytes in suppressing humoral immunity, (3) B cell-mediated anti-tumor immunity and tumor-associated lymphoid structures. She has pioneered studies on how viral infections modulate T follicular helper cells and discovered novel mechanisms of B cell suppression via inflammatory monocytes. Recent publications (2023-2025) investigate T cell therapy efficacy improvement via LSD1 inhibition, antibody-independent SARS-CoV-2 protection, and novel TDC cell biology models. Awards include AAI Early Career Grant (2022) and PRIN2020 coordination (2021). Teaching roles include courses in pathology and immunology for medicine and biomedical programs. Active in professional organizations: Vice-coordinator of the PhD Program in Molecular Medicine, member of AAI, SIICA, and NIBIT. Serves on editorial boards for Frontiers in Immunology and Faculty Opinions .

Stephen Ramseyمشاهده پروفایل

دانشیار

• Computational Systems Biology
• Bioinformatics
• Precision Medicine
• +۶ مورد دیگر

Stephen Ramsey, an Associate Professor at Oregon State University, holds dual appointments in the School of Electrical Engineering and Computer Science (College of Engineering) and the Department of Biomedical Sciences (Carlson College of Veterinary Medicine). With a PhD in Physics from the University of Maryland, his postdoctoral training in computational genomics at the University of Washington, and professional experience at the Institute for Systems Biology and Center for Infectious Disease Research, Ramsey bridges computational methods with biomedical applications. Education : Ph.D., Physics, University of Maryland; M.S., Physics, University of Maryland; Sc.B., Mathematical Physics, Brown University Ramsey specializes in computational systems biology , focusing on bioinformatics , biomedical knowledge graphs , and precision medicine . His research integrates machine learning , gene regulatory network modeling , and multi-omics data analysis to address challenges in rare disease diagnostics , drug monitoring , and inflammatory disease mechanisms . Current work includes AI-driven biomedical translation and electrochemical biosensor development for non-invasive diagnostics . Recent publications highlight knowledge graph applications in translational biomedicine , causal network inference in clinical-environmental data integration , and cross-species cancer transcriptomics . His team develops tools like RTX-KG2 and PloverDB to standardize biomedical data sharing and semantic reasoning . Scientific Awards : 2019 Zoetis Award (Carlson College of Veterinary Medicine) 2016 NSF CAREER Award 2016 PhRMA New Investigator Award 2010 NIH K25 Mentored Quantitative Research Award Ramsey advises in computational biology courses (CS 446/546) and contributes to biomedical AI through projects like mediKanren for rare disease diagnostics . His NSF-funded research explores gene expression noise and regulatory network dynamics , while NIH and PhRMA grants support his translational medicine initiatives. He leads the Ramsey Laboratory , which develops graph-based reasoning tools for biomedical data translation and multi-omics integration . The lab's work spans comparative oncology models, electrochemical biosensors , and knowledge graph infrastructure for clinical decision support .

Philip Osdobyمشاهده پروفایل

استاد

• Bone Biology
• Cellular Immunology
• Regenerative Medicine
• +۳ مورد دیگر

Philip Osdoby is a Professor in the Department of Biology at Washington University. His research focuses on bone development, pathological bone loss, and regenerative medicine, particularly cell-based therapies and tissue engineering. He investigates cell-molecular interactions involving osteoclasts, osteoblasts, immune cells, and vascular cells, emphasizing endocrine and local signaling pathways. His work spans bone biology, cellular immunology, and molecular mechanisms underlying skeletal disorders. Key areas include osteoclastogenesis regulation, cytokine signaling (e.g., IL-1, TNF-α), chemokine receptor (CXCR4) roles in osteoclast recruitment, and biomineralization processes. He explores autocrine feedback mechanisms (e.g., iNOS/NO pathways) and the interplay between angiogenesis and bone resorption in vivo models like the chick chorioallantoic membrane. Publications highlight osteoclast formation from RAW 264.7 cells, galectin-3 isoforms, and SDF-1-driven osteoclast migration. His studies often integrate in vitro and in vivo approaches to dissect bone cell microenvironment dynamics. Philip Osdoby holds no explicitly listed scientific awards. His lab’s research has contributed to understanding osteoporosis, inflammatory bone diseases, and regenerative strategies for bone repair.

Mark Rossمشاهده پروفایل

دانشیار

• Immunology
• Exercise Physiology
• Ageing
• +۶ مورد دیگر

Mark Ross is an Associate Professor at Heriot-Watt University, affiliated with the School of Energy, Geoscience, Infrastructure and Society and the Institute for Life and Earth Sciences. He holds roles as Director of Research for the Sport and Exercise Science department and Programme Director for the BSc (Hons) Sport and Exercise Science. He chairs the EGIS Research Ethics Committee and previously served as Programme Leader at Edinburgh Napier University. Education includes a 1st Class Honours Degree in Sport and Exercise Science from Heriot-Watt University (2009, awarded James Watt Medal), an MRes in Exercise Physiology from Waterford Institute of Technology (2011), and a PhD in Exercise Physiology from Edinburgh Napier University (focused on endothelial progenitor cells). His research explores immune cell contributions to inflammation and tissue repair, leveraging exercise as a modulator. Techniques include flow cytometry to study immune cell activation in human samples from exercise studies. Key interests span T-cells, macrophages, aging, and exercise-induced immunological changes. Recent articles highlight work on ultra-endurance exercise's effects on T-cells, vascular aging in centenarians, and exercise-induced progenitor cell mobilization. His studies often integrate clinical, immunological, and physiological perspectives. Awards: James Watt Medal (2009) PhD projects include exercise's role in T-cell-mediated inflammation, immune health in athletes, and exercise in inflammatory conditions. He actively seeks research grants and collaborates on global projects like VascAgeNet. His work contributes to UN SDGs related to health and longevity. Labs/Teams: Active within the Institute for Life and Earth Sciences, collaborating on vascular aging, exercise immunology, and cardiometabolic disease research.

• Immunology
• Transplant Immunology
• T Cell Immunology
• +۷ مورد دیگر

Nicolle Litjens is an Assistant Professor at Erasmus MC, Faculty of Medicine, in the Department of Internal Medicine. Her research is centered on immunological mechanisms in organ transplantation, particularly focusing on T-cell responses, immune monitoring, and immunosuppression in kidney and liver transplant recipients. Her research interests include T cell immunology , alloreactive T cell dynamics , antibody-mediated rejection , and the impact of bariatric surgery on immune function . She employs advanced techniques such as single-cell RNA sequencing and flow cytometry to investigate immune cell phenotypes and functions in clinical contexts. The recent publications highlight a strong trend toward translational immunology , with emphasis on donor-specific hyporesponsiveness , polyfunctional T cells , and intracellular pharmacokinetics of immunosuppressive drugs . Her work bridges molecular immunology with clinical outcomes in transplantation. She has contributed to over 75 research outputs, including original articles and reviews, and has supervised several junior researchers. Her collaborative network spans national and international institutions in the field of transplant immunology.

Elisa Gomez Perdigueroمشاهده پروفایل

عضو هیئت علمی

• Immunology
• Developmental Biology
• Cell Biology
• +۹ مورد دیگر

Elisa Gomez Perdiguero is a Permanent Researcher at the Institut Pasteur in Paris, affiliated with the Membrane, Cytoskeleton and Cell Division unit. She leads the research group focused on the development, maintenance, and functions of tissue-resident macrophages, with a particular emphasis on their embryonic origins and roles in homeostasis and tissue repair. Her work bridges immunology, developmental biology, and cell biology, and she is the Principal Investigator of the ERC-funded project 'ResidentMacroPhage'. Her research primarily investigates the role of yolk sac-derived erythro-myeloid progenitors (EMPs) in generating tissue-resident macrophages such as microglia, Kupffer cells, and Langerhans cells, which self-maintain independently of hematopoietic stem cells (HSCs). She uses mouse and zebrafish models, along with advanced techniques like flow cytometry, lineage tracing, and transgenesis, to explore the ontogeny and functional specialization of macrophages during development and in response to injury. The trends in her recent publications highlight a consistent focus on developmental hematopoiesis, macrophage heterogeneity, and the interplay between macrophages and endothelial cells. Her work has demonstrated the critical role of early macrophage waves in shaping immune and vascular development, with implications for regenerative medicine and inflammatory diseases. Scientific awards and recognitions include: ERC-2016-StG _ResidentMacroPhage – Development, Maintenance and Functions of Resident Macrophages She has actively mentored numerous PhD students and postdoctoral researchers, including Lorea Iturri, Rebeca Ponce Landete, Alina Sommer, and others. Her lab has received funding from major programs such as LabEx Revive and the IP Stem Cell Initiative, supporting research in regenerative biology and medicine. She is currently recruiting for fully funded postdoctoral and PhD fellowships. Elisa Gomez Perdiguero's team collaborates within transversal programs such as 'Mother and Child Health' and participates in the broader Institut Pasteur ecosystem focused on precision medicine and open science.

Pierre Guermonprezمشاهده پروفایل

پژوهشگر

• Immunology
• Cellular Immunology
• Cancer Immunotherapy
• +۶ مورد دیگر

Pierre Guermonprez is a Researcher at the Pasteur Institute in Paris. His work focuses on dendritic cell biology, tumor immunology, and adaptive immunity, with an emphasis on Cancer immunotherapy Tumor microenvironment manipulation T cell memory development Myeloid cell reprogramming in disease Recent publications highlight his contributions to understanding FLT3L-based dendritic cell therapies Mechanisms of cross-priming in tumors DC subset cooperation for immune activation Neoantigen response modulation His research spans both murine and human models of dendritic cell development. Current advisees include PhD students Louise Gorline , Jérémie Borneres , Aurélie Semervil , Matthieu Rastello , and Nathan Vaudiau , along with Master’s student Bilge Demerci . Team members also include technical staff, postdocs, and administrative personnel.