Nicolle Litjens

Nicolle Litjens is an Assistant Professor at Erasmus MC, Faculty of Medicine, in the Department of Internal Medicine. Her research is centered on immunological mechanisms in organ transplantation, particularly focusing on T-cell responses, immune monitoring, and immunosuppression in kidney and liver transplant recipients.

Her research interests include T cell immunology, alloreactive T cell dynamics, antibody-mediated rejection, and the impact of bariatric surgery on immune function. She employs advanced techniques such as single-cell RNA sequencing and flow cytometry to investigate immune cell phenotypes and functions in clinical contexts.

The recent publications highlight a strong trend toward translational immunology, with emphasis on donor-specific hyporesponsiveness, polyfunctional T cells, and intracellular pharmacokinetics of immunosuppressive drugs. Her work bridges molecular immunology with clinical outcomes in transplantation.

She has contributed to over 75 research outputs, including original articles and reviews, and has supervised several junior researchers. Her collaborative network spans national and international institutions in the field of transplant immunology.