Sebastiaan Heidt

Sebastiaan Heidt is a Full Professor in the Department of Internal Medicine at Erasmus MC, a leading academic medical center in the Netherlands. His work is centered on advancing transplant immunology, particularly in the context of kidney transplantation and immunological risk assessment.

His research focuses on HLA antibodies, memory B cells, epitope matching, and immunological risk stratification in organ transplantation. He investigates how pre-existing immune memory impacts graft survival and how novel therapies like belimumab and alemtuzumab can be used to modulate immune responses pre- and post-transplant. His work bridges clinical practice with immunological research, aiming to improve donor-recipient matching and long-term outcomes.

The most recent articles highlight trends in personalized immunosuppression, equitable organ allocation via eplet matching, and pharmacokinetic modeling of induction therapies. Collectively, his publications emphasize a shift toward precision medicine in transplantation, leveraging immunological profiling to reduce rejection and optimize graft survival.

He is actively involved in international research collaborations, including the EU-funded ULISES project, which explores innovative cellular therapies for sensitized transplant candidates. His contributions include public engagement, such as interviews discussing T-cell therapy to expand donor opportunities for highly sensitized patients.

• Expertise in HLA and transplant immunology
• Leader in immunological risk assessment for kidney transplants
• Active contributor to EU-funded translational research
• Focus on improving access to transplantation for immunologically high-risk patients