Dave Roelen

Dave Roelen is a Lecturer in the Department of Internal Medicine at Erasmus MC, Faculty of Medicine, Netherlands. His work is centered on transplant immunology, with a strong focus on HLA antibodies, kidney transplantation outcomes, and B-cell mediated immune responses.

His research interests include:

• HLA Antibody detection and significance
• Memory B cell profiling in transplant recipients
• Immunological risk stratification before transplantation
• Impact of HLA mismatches on graft survival
• Role of donor-specific antibodies in kidney graft rejection
• Mesenchymal stem cells in immunomodulation

Dave Roelen's recent publications (2025) highlight his active role in clinical immunology research, particularly in uncovering memory B-cell profiles using belimumab, analyzing multicenter data on HLA mismatches, and investigating the combined impact of donor age and anti-HLA antibodies on graft outcomes. His work frequently appears in journals like HLA and Frontiers in Immunology, reflecting a strong emphasis on translational immunology and transplant medicine.

Scientific contributions and recognitions:

• Active contributor to high-impact transplant immunology research
• Co-authored tribute to pioneering immunologist Frans H.J. Claas, underscoring his integration in the international transplant community

Dave Roelen has been involved in significant collaborative research projects, often working with leading figures in nephrology and immunology at Erasmus MC. While no formal grants are listed, his multicenter studies suggest participation in funded research initiatives. He contributes to advancing pre-transplant risk assessment models and understanding the immunological memory in transplant patients.

He is associated with the transplant immunology research team at Erasmus MC, which focuses on improving long-term graft survival through personalized immunological evaluation and novel therapeutic strategies.