جست‌وجوی استاد و پژوهشگر

• Biomarkers
• Quantitative Analysis in Pathology
• Medical Data Interpretation
• +۵ مورد دیگر

Robert Camp is a Researcher at Yale School of Medicine , affiliated with the Department of Pathology . His work focuses on biomarkers , quantitative analysis , and automation in pathology . Education MD, Yale University School of Medicine (1997) PhD, Yale University School of Medicine, Immunology (1992) BA, Swarthmore College, Biology (1987) His research interests include tumor microenvironment , biomarker quantification , and histopathology standardization , with a focus on renal cell carcinoma and interstitial lung disease . Recent publications highlight automation tools like the AQUA System and X-Tile software for tumor subpopulation analysis . Scientific contributions include the Charles W. Bomfalk Prize for medical student teaching and leadership in the Breast Cancer Alliance . He has collaborated extensively with researchers such as David Rimm and Harriet Kluger on projects involving tumor vascularity and immunotherapy targets .

• Neurodegenerative Diseases
• Alzheimer's Disease
• Parkinson's Disease
• +۱۲ مورد دیگر

Frédéric Calon is a Full Professor in the Faculty of Pharmacy at Université Laval, where he leads a prominent research program focused on neurodegenerative disorders, particularly Alzheimer’s and Parkinson’s diseases. His work bridges molecular neuroscience, nutritional interventions, and blood-brain barrier drug delivery, using both animal models and human post-mortem studies. He is actively involved in training graduate students and postdoctoral fellows and maintains international collaborations, including the LIA OptiNutriBrain with Bordeaux. B.Sc. in Biochemistry, Université Laval (1989–1992) M.Sc. in Pharmacy, Université Laval (1992–1995) B.Pharm., Université Laval (1994–1998) Ph.D. in Pharmacy, Université Laval (1998–2001) Postdoctoral Training, University of California, Los Angeles (UCLA), Dept. of Medicine (2001–2003) Dr. Calon’s research centers on three main axes: (1) the role of nutrition—especially omega-3 fatty acids—in neurodegeneration; (2) synaptic and molecular pathology in Alzheimer’s and Parkinson’s diseases; and (3) the interplay between peripheral metabolic disorders and brain health, including insulin signaling and thermoregulation. He also investigates the blood-brain barrier as a therapeutic gateway for drug delivery. His recent publications reflect a strong focus on Alzheimer’s disease mechanisms, including tau phosphorylation, amyloid-beta pathology, synaptic dysfunction, and the impact of diet and metabolism. He has also made key contributions to understanding essential tremor through post-mortem brain studies. His work frequently involves transgenic mouse models, such as the 3xTg-AD, and integrates behavioral, biochemical, and imaging techniques. Dr. Calon’s research is supported by major grants from CIHR and the Alzheimer Society of Canada. He mentors a large team of doctoral, master’s, and postdoctoral researchers, many of whom are supported by competitive scholarships. His lab has developed unique expertise in in situ brain perfusion and quantitative BBB transport analysis. He leads studies on novel therapeutic strategies, including repurposing beta-3 adrenergic agonists, optimizing nutraceutical formulations, and enhancing brain delivery of biologics via transferrin receptor-targeted vectors. His work on essential tremor has identified GABA receptor deficits and amyloid-beta accumulation in the cerebellum, suggesting a neurodegenerative basis for the disorder.

Travis W. Heinمشاهده پروفایل

استاد

• Medical Physiology
• Vascular Biology
• Diabetes Research
• +۳ مورد دیگر

Travis W. Hein, PhD, is a Professor in the Department of Medical Physiology at Texas A&M University's School of Medicine. His research focuses on microvascular dysfunction in diabetes, particularly in retinal and coronary microvessels, and its implications for vision loss and heart failure. He also investigates spaceflight-associated neuro-ocular syndrome (SANS) mechanisms in astronauts. Hein holds significant teaching awards, including the 2023 R. Kelly Hester Distinguished Teaching Award and membership in the Academy of Distinguished Medical Educators. Education: BA in Biology from St. Olaf College (1992), PhD in Medical Physiology from Texas A&M Health Science Center (1997). Research interests emphasize molecular mechanisms of vasomotor regulation, diabetes-induced vascular damage, and space health challenges. His work identifies therapeutic targets for microvascular diseases and explores ocular blood flow dynamics in space environments. Key publications highlight breakthroughs in retinal degeneration therapies (e.g., stanniocalcin-1), diabetic microvascular complications, and cardiovascular dysfunction mechanisms. His articles span 20+ years, demonstrating sustained contributions to vascular biology and translational medicine. Scientific awards: 2023 R. Kelly Hester Distinguished Teaching Award 2021 Elected to Academy of Distinguished Medical Educators 2017 Texas A&M Distinguished Teaching Award Grants and mentoring: Extensive NIH-funded research programs and training of graduate students/postdocs in cardiovascular and ocular physiology. Collaborates on space health initiatives through NASA partnerships. Labs/Teams: Directs Texas A&M's Microvascular Physiology Lab, focusing on translational research in diabetes and space health. Active in multidisciplinary teams addressing ocular vascular dysfunction and cardiac microcirculation.

Edward Sanderمشاهده پروفایل

استاد

• Biomedical Engineering
• Multiscale Mechanics
• Tissue Engineering
• +۷ مورد دیگر

Edward Sander is a Professor in the Department of Biomedical Engineering at the University of Iowa's College of Engineering, where he has been a faculty member since 2011. He also holds researcher positions at the Iowa Institute for Biomedical Imaging and the Iowa Technology Institute, contributing to interdisciplinary research in biomedical engineering and imaging sciences. Education: PhD in Biomedical Engineering, Tulane University, 2006 MS in Biomedical Engineering, Tulane University, 2004 BSE in Chemical Engineering, The University of Texas at Austin, 2000 His research focuses on multiscale mechanics and modeling of biological tissues, with particular emphasis on wound healing, skin tissue engineering, microvessel formation, and the biomechanics of connective, vascular, and ocular tissues. He employs advanced microscopy and image-based computational modeling techniques to study tissue damage and mechanical behavior across scales. His work integrates biomaterials, tissue engineering, and mechanobiology to develop engineered tissue systems and understand native tissue function. Dr. Sander is a member of the Biomedical Engineering Society and leads the Sander 3MT Lab, which focuses on mechanistic, microstructural, and multiphysics modeling of biological materials. While specific publications are not listed in the provided text, his research output is tracked through Google Scholar, indicating an active publication record in his fields of expertise. Scientific Awards and Honors: Robert and Virginia Wheeler Faculty Fellow in Engineering Dr. Sander advises graduate students and likely participates in externally funded research projects, though specific grants and advisees are not detailed. His affiliations with major research institutes at the University of Iowa underscore his role in advancing translational biomedical research and engineering innovation. Research Affiliations: Iowa Institute for Biomedical Imaging Iowa Technology Institute

Ammar Hooriمشاهده پروفایل

عضو هیئت علمی

• Cardiac Imaging
• Data Science
• Artificial Intelligence
• +۷ مورد دیگر

Ammar Hoori, PhD, is a Research Assistant Professor in the Department of Biomedical Engineering at Case Western Reserve University, affiliated with both the Case School of Engineering and School of Medicine. His research focuses on cardiac image analysis, leveraging advanced techniques like image registration, deep learning, and survival analysis. He leads NIH-funded projects involving CT calcium scoring, IVOCT, and chest CT imaging, collaborating with cardiologists from University Hospitals Cleveland and engineers from CWRU. His work emphasizes developing calcium-omics and fat-omics features to improve cardiovascular disease prediction. His research team employs cutting-edge methods such as deep learning segmentation for epicardial adipose tissue analysis, aiming to optimize patient care through AI-driven risk stratification. Hoori’s contributions include the development of the DeepFat algorithm for automated fat quantification and collaborations on stent under-expansion prediction using OCT imaging. He is also involved in the Biomedical Imaging Laboratory (BMIL), contributing to advancements in cryo-imaging and 3D visualization techniques. Key areas of innovation include AI-enabled risk prediction for heart failure, MACE (Major Adverse Cardiovascular Events), and coronary artery disease using opportunistic data from routine CT scans. His work bridges clinical and engineering expertise to advance non-invasive diagnostic tools and personalized medicine strategies.

• Cell Biology
• Immunology
• Biophysics
• +۳ مورد دیگر

Pablo J. Sáez is a researcher at the University of Hamburg's Medical School, affiliated with the Department of Cell Biology and Immunology. His work focuses on cellular mechanisms of migration, signaling, and structural dynamics in immune and kidney-related cells. He explores processes like dendritic cell migration, podocyte dysfunction in nephropathy, and the role of calcium channels in cellular behavior. His research integrates biophysical and immunological approaches to understand how cell shape, cytoskeletal dynamics, and microenvironment interactions regulate immune responses and disease progression. Notable contributions include studies on membrane blebbing, SPARC-driven tumor progression, and the development of imaging tools for cellular analysis. Key areas of investigation include: cell shape sensing, actomyosin regulation, and the role of septins in immune cell motility. His articles highlight interdisciplinary methods, combining live-cell imaging, molecular biology, and computational modeling to dissect cellular decision-making processes during migration and disease. Scientific achievements include foundational work on exopher-formation in kidney disease and guidelines for functional assays in dendritic cells. His research bridges basic science and clinical applications, aiming to uncover therapeutic targets in immune and renal disorders.

Mary D. (Molly) Frame (McMahon)مشاهده پروفایل

استاد

• Oxygen Delivery
• Microvascular Physiology
• Inflammation and Vascular Disease
• +۷ مورد دیگر

Dr. Mary D. (Molly) Frame is a Professor in the Departments of Biomedical Engineering and Physiology and Biophysics at Stony Brook University, and Undergraduate Program Director. Her research focuses on microvascular networks, oxygen delivery mechanisms, and inflammatory effects in conditions like diabetes and obesity. She holds a Ph.D. in Physiology and A.B. in Biology from the University of Missouri-Columbia. Her work integrates computational modeling, in vitro/ex vivo experiments, and genomic approaches to understand arteriolar flow dynamics. Key topics include gap junction activity, flow sensing by endothelium, and the impact of particle-tube interactions in microvessels. Teaching responsibilities include courses such as BME 100, BME 205, and advanced physiology modules. Her research emphasizes translational applications in vascular disease and biofluid mechanics. Labs/Teams: Active in the Institute of Molecular Cardiology and collaborates across disciplines within Stony Brook's biomedical engineering and physiology programs.

Jan Lammerdingمشاهده پروفایل

استاد

• Cell nucleus mechanobiology
• Mechanotransduction
• Cancer cell migration and metastasis
• +۵ مورد دیگر

Jan Lammerding is a Professor at Cornell University's Meinig School of Biomedical Engineering and the Weill Institute for Cell and Molecular Biology. His research focuses on nuclear mechanobiology, investigating how mechanical forces affect nuclear structure and function in cancer metastasis and muscular dystrophies. He has developed microfluidic platforms to study nuclear deformation and holds fellowships from BMES, AIMBE, and ASCB. Education: Diplom Ingenieur (RWTH Aachen), B.E. (Dartmouth), Ph.D. (MIT) Leadership: Director of Graduate Studies (2011-2024), Associate Director of Meinig School (2024-) Research spans nuclear envelope rupture in cancer cells, mechanotransduction pathways, and Ledercq Foundation-funded projects on laminopathies. His lab has produced 15+ articles (2023-2025) covering topics like microtubule-induced nuclear damage , 3D hydrogel migration , and mechanical stress epigenetic effects . Awards include Keith Porter Medal , NSF CAREER , and Cornell Teaching Excellence honors.

Shigao Chenمشاهده پروفایل

استاد

• Ultrasound Imaging
• Shear Wave Elastography
• Microvessel Imaging
• +۳ مورد دیگر

Shigao Chen, Ph.D., serves as Professor of Radiology and Biomedical Engineering at Mayo Clinic College of Medicine. His primary appointment is in the Department of Radiology with joint appointment in the Department of Physiology & Biomedical Engineering. A leading innovator in ultrasound technology development, Dr. Chen directs a high-impact translational research program focused on quantitative disease evaluation. His core research interests include: Shear wave elastography (notably Comb-push Ultrasound Shear Elastography - CUSE) Super-resolution microvessel imaging for vessels under 50 microns Liver steatosis quantification via Ultrasound Attenuation Coefficient Therapeutic ultrasound for targeted drug delivery These technologies address critical clinical needs in oncology, hepatology, rheumatology, and inflammatory diseases. Analysis of recent publications reveals dominant trends in quantitative ultrasound biomarkers, with strong emphasis on clinical validation across liver/kidney diseases and inflammatory conditions. His work consistently bridges engineering innovation with practical clinical implementation. Professional recognition includes: Fellow of National Academy of Inventors (2021) Fellow of American Institute for Medical and Biological Engineering (2021) Distinguished Investigator Award (2023) Carman Award of Research Excellence (2022) Dr. Chen maintains active research leadership through multiple NIH-funded projects including R01 grants from NIDDK, NIBIB, and NIAMS. His laboratory has successfully translated CUSE technology into global clinical practice through industry licensing. Current projects focus on renal microvessel imaging for chronic kidney disease and ultrasound evaluation of Crohn's disease.

• Retinal Imaging
• Biomedical Image Analysis
• Artificial Intelligence in Medicine
• +۱۲ مورد دیگر

Manuel Trucco is a Professor in the Department of Computing, with a research focus on biomedical image analysis, particularly in retinal imaging and its applications in systemic diseases. His work integrates artificial intelligence, deep learning, and image processing to develop tools for assessing retinal vasculature and detecting biomarkers for conditions such as diabetes, cardiovascular disease, and dementia. His research interests lie at the intersection of computer science and clinical medicine. He specializes in retinal vessel segmentation , tortuosity measurement , fractal dimension analysis , and automated assessment platforms like VAMPIRE. His studies leverage large datasets including the UK Biobank and Lothian Birth Cohort to correlate retinal microvasculature changes with systemic diseases. He applies both handcrafted features and deep learning models to enhance classification accuracy in retinal image analysis. The trends in his recent publications reflect a strong emphasis on AI-driven diagnostics , automated retinal image analysis , and non-invasive biomarker discovery . His work spans technical algorithm development and clinical validation, targeting applications in diabetic retinopathy, coronary artery disease, Alzheimer's, and glaucoma. The integration of multi-resolution modeling, particle swarm optimization, and ultra-wide field imaging demonstrates innovation in both methodology and scalability. VAMPIRE: Vessel Assessment and Measurement Platform for Images of the Retina Research supported by extensive project funding from 2007–2024 Active contributor to large-scale cohort studies (UK Biobank, Lothian Birth Cohort) Supervised 10 research students or early-career researchers h-index of 37 with over 5,800 citations Manuel Trucco leads a research group focused on retinal image analysis and biomedical computing , contributing to the development of software platforms and AI models for clinical use. His team works on both fundamental image processing techniques and their translation into medical practice, particularly in primary and secondary care settings.

Mariana De Nizمشاهده پروفایل

استادیار

• Infectious Diseases
• Host-Pathogen Interactions
• Microscopy
• +۳ مورد دیگر

Dr. Mariana De Niz serves as Research Assistant Professor in the Department of Cell and Developmental Biology and Manager of the Nikon Imaging Center at Northwestern University's Feinberg School of Medicine since 2023. With two decades of international experience across Europe, Africa, and Latin America, she specializes in infectious disease research and advanced imaging techniques for studying host-pathogen interactions, particularly in parasitic infections. Her educational background includes a BS from the University of Glasgow (2010), MS from London School of Hygiene and Tropical Medicine (2011), and a PhD from the University of Bern (2016), complemented by specialized training in tropical medicine and vaccine development. Postdoctoral work at Harvard School of Public Health (2018), Instituto de Medicina Molecular (2021), and Institut Pasteur (2022) honed her expertise in microscopy and infectious diseases. Dr. De Niz's research integrates intravital, super-resolution, and optoacoustic imaging to investigate parasite sequestration mechanisms in trypanosomiasis. She pioneers open-access microscopy tools and advocates for democratizing imaging technology globally. Her work spans parasitology, vascular biology, and bioengineering, with recent focus on AI-powered microscopy and 3D microvessel models to understand parasite behavior in host vasculature. Analysis of her 38+ publications reveals strong emphasis on innovative imaging approaches to parasitology, including microfluidics for parasite behavior studies and computational methods for image analysis. These works bridge molecular mechanisms with translational applications in tropical disease research, particularly regarding Trypanosoma species sequestration and vascular damage. Professional memberships include Quarep-LiMI (2024-present), where she contributes to global guidelines for imaging scientist career development. She actively builds bioimaging networks across the Americas to enhance research capacity and promote open science practices in microscopy. No scientific awards were reported in the provided materials. While specific grant details are unavailable, her leadership in core facility management and extensive publication record indicate active research support. Dr. De Niz mentors researchers through the Nikon Imaging Center, providing technical training in advanced microscopy techniques. As Nikon Imaging Center Manager, she oversees state-of-the-art microscopy resources and collaborates with international consortia to advance imaging science. Her initiatives focus on sustainable career paths for imaging professionals and expanding access to cutting-edge microscopy worldwide, particularly in resource-limited settings.

• Microfluidics
• Biomedical Engineering
• Soft Matter Physics
• +۳ مورد دیگر

Daniele Vigolo is a Senior Lecturer at the School of Biomedical Engineering, University of Sydney. He holds an honorary position at the University of Birmingham and is affiliated with the Sydney Nano Institute. His research focuses on microfluidics, soft matter, and complex fluids, with applications in biomedical engineering, particularly in studying deep vein thrombosis and biomaterials. Education: Laurea (5-year Master) in Nuclear Engineering from Politecnico di Milano (2006), PhD in Radiation Science and Technology (2010). Postdoctoral positions at Harvard, Princeton, and ETH Zurich before joining Birmingham in 2015 and Sydney in 2020. Research interests include bio-fluid dynamics, microfluidic platforms for disease modeling, and functional biomaterials. His work combines experimental and theoretical approaches to investigate multiphase flows, thermophoresis, and interfacial phenomena. Recent articles highlight advancements in neuromorphic cytometry, biomolecular condensates, and microfluidic applications in healthcare. He has secured grants for projects like the 3D microvessel-on-chip platform and groundwater quality sensors. Supervised 9 PhD students and 2 postdocs at Birmingham, focusing on thrombosis, biomaterials, and microbial fuel cells. Labs/Teams: Active in Sydney's Biomedical Engineering lab, collaborating with interdisciplinary teams on microfluidic biosensors and vascular models.

Brandon Helfieldمشاهده پروفایل

استادیار

• Biomedical Ultrasound Imaging
• Focused Ultrasound Therapy
• Molecular Biophysics
• +۵ مورد دیگر

Brandon Helfield is an Assistant Professor at Concordia University with cross-appointments in Physics and Biology. He holds the Tier II Canada Research Chair in Molecular Biophysics in Human Health and serves as a Junior Scientist at the Physical Sciences Platform of Sunnybrook Research Institute. His research bridges biomedical ultrasound, microbubble dynamics, and therapeutic applications. Education : PhD in Medical Biophysics (University of Toronto), BSc in Physics (McGill University), Postdoctoral Fellowship in Cardiology (University of Pittsburgh) Research Interests : Dr. Helfield focuses on biomedical ultrasound imaging and therapy, particularly microbubble-based technologies for targeted drug/gene delivery to treat cardiovascular diseases. His recent work explores CRISPR-Cas9 delivery to stem cells, immunomodulation via focused ultrasound, and super-resolution imaging algorithms. Publication Trends : His research spans ultrasound physics, microbubble dynamics, and clinical translation. Key areas include cavitation mechanics, vascular delivery optimization, and machine learning applications for imaging analysis. Awards : Burroughs Wellcome Fund Career at the Scientific Interface Award, Arthur E. Weyman Young Investigator Award, European Symposium on Ultrasound Young Investigator Award

• Tissue Engineering
• Regenerative Medicine
• Vascular Biology
• +۴ مورد دیگر

Dino Ravnic is a Professor in the Department of Surgery, Division of Plastic Surgery at the Penn State College of Medicine, with dual affiliation at the Penn State Cancer Institute focusing on Next-Generation Therapies. He directs the Plastic Surgery Research Laboratory managed by Dr. Srinivas Koduru, driving innovation in reconstructive microsurgery through engineered tissue solutions. Education: Doctor of Osteopathic Medicine (DO) Master of Public Health (MPH) Master of Science (MSc) His research pioneers vascularized tissue engineering using adipose-derived stem cells and endothelial cells to create patient-specific implants that overcome donor-site morbidity in free-flap surgery. The lab specializes in 3D bioprinting vascular networks, scaffold fabrication from adipose biomolecules, and microvasculature optimization through cross-disciplinary collaboration with materials scientists and vascular biologists. Recent expansions include hernia/bone repair and clinical applications of small RNAs. Current publications (2024-2025) reveal three dominant trajectories: biomaterial innovation for implant monitoring (e.g., citrate polymers with dual-modal imaging), vascularized adipose engineering for soft-tissue reconstruction, and ultrasound-mediated therapeutic systems for bone regeneration and biofilm eradication. These works bridge biomedical engineering, clinical surgery, and molecular biology to solve perfusion challenges in tissue implants. As PI/Co-PI on six NIH-funded projects, Ravnic leads high-impact vascularization research: 3D Printing of Air (NIBIB 2024-2026): Sacrificial ink for vascularized tissue fabrication Host Tissue Manipulation (NHLBI 2023-2025): Inducing hierarchical microvasculature Mechanisms of Micropunctured Angiogenesis (NHLBI 2021-2022): Rapid perfusion for bioprinted flaps The Plastic Surgery Research Laboratory maintains a collaborative ecosystem with materials scientists for scaffold development, biomedical engineers for 3D bioprinting, and vascular biologists for microcirculation optimization. Current initiatives integrate computational modeling with clinical translation, targeting UN Sustainable Development Goals in health innovation through vascularized tissue solutions for cancer reconstruction and trauma recovery.

Timothy W. Secombمشاهده پروفایل

استاد

• Theoretical Physiology
• Microcirculation
• Computational Modeling
• +۱۲ مورد دیگر

Timothy W. Secomb is a Professor at the University of Arizona with joint appointments in the Department of Physiology, Department of Mathematics, and the interdisciplinary programs in Applied Mathematics and Physiological Sciences. He is also affiliated with the BIO5 Institute and the Department of Biomedical Engineering, reflecting his highly interdisciplinary research approach. His research focuses on theoretical and computational modeling of physiological systems, particularly the microcirculation. Key areas include blood flow mechanics in microvessels, oxygen and nutrient transport to tissues, structural adaptation and angiogenesis in vascular networks, and regulation of blood flow through metabolic and mechanical feedback. His work integrates applied mathematics, physiology, and biomedical engineering to understand fundamental mechanisms in health and disease. The recent publications highlight a consistent focus on microvascular oxygen transport, neurovascular coupling, tumor angiogenesis, and computational hemodynamics. The modeling spans from cellular-level processes like red blood cell mechanics and ion diffusion to organ-level systems such as the cerebral cortex and pulmonary circulation. A strong trend is evident in using realistic 3D vascular geometries and developing fast, low-order models for complex physiological systems. Dr. Secomb has made significant contributions to understanding flow resistance, capillary perfusion, and the impact of vascular structure on tissue oxygenation. His models are instrumental in studying hypoxia in tumors and optimizing cancer therapies like thermoradiotherapy and antibody-drug conjugates. BSc in Mathematics, University of Melbourne (1975) MSc in Mathematics, University of Melbourne (1976) PhD in Applied Mathematics, University of Cambridge (1979) Post-Doctoral Training, Columbia University (1981) He has mentored students and researchers in mathematical physiology and continues to lead an active research program. His lab employs a hybrid discrete-continuum modeling framework and collaborates with experimental groups to validate theoretical predictions. Future work is likely to extend into immune-cell trafficking, multi-scale modeling of organ systems, and personalized models for precision medicine applications.