جستجوی استاد راهنمای دانشگاهی

Chih Hung Loمشاهده پروفایل

استادیار

• Neurodegeneration
• Alzheimer's Disease
• Multiple Sclerosis
• +۷ مورد دیگر

Chih Hung Lo is an Assistant Professor in the Department of Biology and Interdisciplinary Neuroscience Program at Syracuse University's College of Arts and Sciences. His research focuses on molecular mechanisms of neurodegeneration and neuroinflammation, with emphasis on autophagy, lysosomal dysfunction, and receptor signaling in Alzheimer's disease and multiple sclerosis. Dr. Lo's educational background includes: Ph.D. from University of Minnesota (2019) B.B.A. from National University of Singapore (2014) B.E. from National University of Singapore (2014) His research spans Neurodegeneration , Alzheimer's Disease , Multiple Sclerosis , Neuroinflammation , Autophagy , and Drug Discovery . The Lo Lab investigates how autophagy and lysosomal dysfunction—driven by inflammatory cytokine receptor signaling (e.g., TNF), lipid dysregulation, and intrinsically disordered proteins (e.g., tau)—contribute to neuroinflammation. They combine interdisciplinary approaches to study receptor structure-function and protein dynamics for biosensor engineering and high-throughput drug screening , with strong focus on nanomedicine for brain targeting . Analysis of his recent publications (2020-2023) reveals dominant themes in lysosomal acidification dysfunction in neurodegeneration, TNFR1 signaling modulation , tau oligomerization , and bioengineering applications for translational neuroscience. His work bridges molecular mechanisms with clinical applications, particularly in Alzheimer's and multiple sclerosis therapeutics. Dr. Lo's scientific honors include: Trainee Professional Development Award, Society for Neuroscience (2023) Selected as Young Scientist for Lindau Nobel Laureate Meeting (2023) BBA Rising Star in Biochemistry & Biophysics (2023) UMN Best Dissertation Award (2020) BME Department Best Dissertation Award (2020) He actively mentors students through Syracuse's graduate programs and serves as Review Editor for Frontiers in Molecular Neuroscience , Guest Editor for International Journal of Molecular Sciences , and peer reviewer for multiple journals. His academic service includes editorial roles for Pharmaceuticals and Immunology , and membership in the Society for Neuroscience. The Lo Lab operates at the neuroscience-bioengineering interface, maintaining collaborations with Yale, Harvard, and Nanyang Technological University. Current projects focus on developing TNFR1 biosensors, tau oligomer-targeted therapies, and nanomedicine platforms for brain delivery, with strong emphasis on clinical translation of basic discoveries.

Gary Zenitskyمشاهده پروفایل

پژوهشگر

• Neuroscience
• Neurodegenerative Diseases
• Environmental Toxicology
• +۳ مورد دیگر

Gary Zenitsky is a Researcher in the Department of Physiology and Pharmacology at the University of Georgia’s College of Veterinary Medicine. His research focuses on neurodegenerative mechanisms, environmental toxin impacts, and mitochondrial dysfunction in diseases like Parkinson’s. Key areas of investigation include neuroinflammation, protein misfolding, and the gut-brain axis. His work bridges molecular biology, toxicology, and translational medicine. Recent studies emphasize the roles of α-synuclein, mitochondrial stress, and environmental exposures in neurodegenerative processes. He explores innovative approaches like microbiome engineering for therapeutic delivery. His research often involves collaborative interdisciplinary methods, including CRISPR-Cas9 systems and advanced cell culture models. Notable contributions include identifying KCa3.1 channels as targets in neuroinflammatory pathways and elucidating manganese’s role in promoting α-synuclein aggregation. He has pioneered methods for isolating primary microglia with enhanced purity, advancing in vitro studies of neuroinflammation. Zenitsky’s work addresses translational challenges in neurotoxicology and neurodegenerative disease treatment. Current projects investigate biomarkers for early Parkinson’s detection and environmental risk factor mitigation strategies.

Antoine Trillerمشاهده پروفایل

استاد

• Neuroscience
• Cell Biology
• Membrane Dynamics
• +۳ مورد دیگر

Antoine Triller is a Professor at the Institut de Biologie de l'École Normale Supérieure (IBENS), Paris, leading the Cell biology of the synapse team. His research focuses on understanding synaptic membrane dynamics and stability, particularly how synaptic receptors are regulated by scaffold proteins and membrane fluidity. Key contributions include pioneering studies on single-particle tracking, super-resolution imaging, and the role of microglia in synapse regulation. Research Themes : Synaptic receptor dynamics, membrane organization, neurodegenerative mechanisms, synaptic plasticity. Technologies : Quantum dot tracking, PALM/STORM imaging, electrophysiology. His work bridges cell biology and neuroscience, with major findings on transient receptor stabilization and the impact of misfolded proteins on neuronal membranes. The team actively investigates α-synuclein's role in neurodegeneration and synaptic glycinergic/GABAergic control. Labs/Teams : Part of the IBENS Neuroscience axis, collaborating with structural biology and computational teams to model synaptic architecture.

Hermann Altmeppenمشاهده پروفایل

پژوهشگر

• Prion Protein Biology
• Alzheimer's Disease
• Neurodegenerative Diseases
• +۳ مورد دیگر

Hermann Altmeppen is a researcher and Head of Research Group at the Institute of Neuropathology, part of the Center for Diagnostics at the Universitätsklinikum Eppendorf (UKE), Hamburg. He is affiliated with the Faculty of Medicine at the University of Hamburg. His research focuses on neurodegenerative diseases, particularly prion protein biology, Alzheimer’s disease mechanisms, and the role of extracellular vesicles in neurological disorders. His work integrates molecular biology, immunology, and translational neuroscience. Key research interests include the role of prion protein shedding, the impact of extracellular vesicles on neuroprotection, and the pathophysiology of Alzheimer’s and other proteinopathies. Altmeppen’s studies explore mechanisms such as ADAM10-mediated proteolytic processing of prion proteins and the implications for disease progression. His recent publications highlight advancements in understanding prion protein interactions with viruses, post-COVID-19 neurological effects, and innovative methods for isolating brain-derived extracellular vesicles. Altmeppen’s work contributes to both basic science and potential therapeutic strategies for neurodegenerative conditions. No academic awards or grants are explicitly mentioned in the provided texts. His lab focuses on neurodegenerative mechanisms, with a particular emphasis on prion protein dynamics and their implications for diseases like Alzheimer’s.

• Neurology
• Imaging Technologies
• Stroke Research
• +۳ مورد دیگر

Peter Ludewig is a Professor at the University Medical Center Hamburg-Eppendorf (UKE), affiliated with the Department of Experimental Medicine and the Medical Faculty. His research focuses on neurovascular mechanisms, stroke pathophysiology, and advanced imaging techniques like Magnetic Particle Imaging (MPI). He leads interdisciplinary projects combining experimental medicine with clinical applications, particularly in cerebral perfusion analysis and neuroinflammation. Key areas of expertise include: stroke therapy development, immune responses in brain injury, and translational imaging technologies. His work bridges basic science and clinical practice, with contributions to understanding neutrophil dynamics, cytokine regulation (e.g., IL-17A), and novel drug delivery systems using nanobodies. Recent studies address cerebral microvascular remodeling, nanopore sequencing for lymphoma diagnosis, and optimizing MPI tracers for real-time perfusion assessment. He collaborates across departments including Neurology, Radiology, and the Cardiovascular Research Center (CVRC).

Meng-meng Fuمشاهده پروفایل

استادیار

• Cell Biology
• Neurodegenerative Diseases
• Glial Cell Biology
• +۳ مورد دیگر

Meng-meng Fu is an Assistant Professor in Cell Biology, Development and Physiology. Her research focuses on understanding glial cell functions at molecular, cellular, and organismal levels, particularly in the context of myelination and neurodegenerative diseases. Her lab investigates Golgi outpost microtubule nucleation in oligodendrocytes, mRNA transport mechanisms, and cytoskeletal organization in astrocytes. Current projects include studying leukodystrophies and astrocyte cytoskeletal interactions. Research interests span mechanisms underlying myelination defects, neurodegenerative protein aggregation, and glial cell biology. Recent work explores how genetic mutations in leukodystrophies reveal critical steps in normal myelination and how microglial senescence impacts remyelination. Her lab employs mouse models, biochemical assays, and biophysical techniques to dissect these processes. Key contributions include identifying TPPP's role in microtubule nucleation for myelination and uncovering the necessity of dynein/dynactin for Mbp mRNA transport. Her publications highlight interdisciplinary approaches bridging cell biology and neurological disease mechanisms.

• Neurodegenerative Diseases
• Biochemistry
• Cell Biology
• +۳ مورد دیگر

Daryl A Bosco, PhD is a Professor at UMass Chan Medical School, holding the Paul J. DiMare Chair in Neurodegenerative Disease. She also has secondary appointments in the T.H. Chan School of Medicine (Biochemistry and Molecular Biotechnology, Neurology) and Morningside Graduate School of Biomedical Sciences (multiple programs including Neuroscience and MD/PhD Program). Education: BS in Chemistry from State University of New York, Binghamton; PhD in Bioorganic Chemistry from Brandeis University Postdoctoral Training: Scripps Research Institute (Alpha-Synuclein Misfolding), Harvard Medical School (ALS Research) Research Focus: The Bosco lab investigates pathogenic mechanisms of ALS-associated proteins (SOD1, FUS/TLS, Profilin-1, TDP-43) using multidisciplinary approaches including biochemistry, cell biology (iPSC technology), biophysics, and in vivo models. Key projects include studying protein misfolding, nucleocytoplasmic transport defects, and microglial dysfunction in ALS. Publications Trends: Recent work explores iPSC-derived microglia for ALS modeling, traumatic brain injury models for neurodegeneration, and FUS-nucleoporin interactions in nucleocytoplasmic transport. Earlier studies focused on SOD1 misfolding, stress granule assembly, and proteostasis in neurodegenerative diseases. Training & Collaboration: The lab actively participates in graduate education through Morningside Graduate School of Biomedical Sciences and offers research opportunities for MD/PhD students. Dr. Bosco collaborates extensively with ALS researchers including John Landers, Robert Brown, and Nils Henninger. Facilities: The Bosco Lab maintains active research infrastructure with a dedicated website ( boscolab ) and collaborates with core facilities for advanced imaging and proteomics.

Hannah Scheiblichمشاهده پروفایل

پژوهشگر

• Neuroimmunology
• Ageing
• Neurodegenerative Diseases
• +۳ مورد دیگر

Hannah Scheiblich is a Max Planck Research Group Leader at the Max Planck Institute for Biology of Ageing (Cologne, Germany) since 2024. Her work focuses on the neuroimmunology of aging , particularly the role of microglia in neurodegenerative diseases like Alzheimer's and Parkinson's. She investigates how microglial dysfunction contributes to chronic inflammation and pathology. PhD in Natural Sciences (Dr. rer. nat., 2015, University of Veterinary Medicine Hannover) Master of Science (MSc, 2011, University of Veterinary Medicine Hannover) Bachelor of Science (BSc, 2009, Philipps-University of Marburg) Her research spans three key areas: Mechanisms of microglial phagocytosis and intercellular cargo transfer via tunneling nanotubes Role of NLRP3 inflammasome activation in neurodegeneration Regulation of microglial migration and function through signaling pathways like NO/cGMP and HO-1/CO Publications highlight her work on: α-synuclein degradation strategies Tau pathology in Alzheimer's disease Neuroinflammatory signaling in prion diseases Cross-talk between neurons and microglia Alcohol-induced microglial dysfunction Scientific awards include: Best Poster Prize (2023, 7th Venusberg Meeting) 3rd place Best Paper Prize (2022, German Center for Neurodegenerative Diseases) Mark A. Smith Prize (2017, Journal of Neurochemistry) She has received funding from: Alzheimer Forschung Initiative (2024-2027) Gemeinnützige Hertie Stiftung (2020-2023) Cluster of Excellence ImmunoSensation (2023)

Bryce Durafourtمشاهده پروفایل

استادیار

• Health Systems Improvement
• Telemedicine
• Neurology
• +۵ مورد دیگر

Dr. Bryce Durafourt is an Assistant Professor in the Department of Medicine, Division of Neurology at Queen’s University. He completed his B.Sc. in Microbiology and Immunology, M.Sc. in Neuroscience, and M.D.,C.M. at McGill University, followed by neurology residency at Queen’s University. His clinical practice focuses on acute care neurology, including vascular neurology, epilepsy, and electroencephalography (EEG). He leads the resident-led urgent neurology clinic and directs inpatient stroke and general neurology clinics. His research centers on health systems improvement, quality care delivery, and telemedicine to enhance access to neurological care in rural/remote areas. Key interests include stroke management, innovative care modalities, and equitable healthcare access. Dr. Durafourt holds a cross-appointment with the Translational Institute of Medicine (TIME) at Queen’s University. His work emphasizes translating research into clinical practice, particularly through virtual healthcare models and optimizing stroke care pathways.

Kiavash Movahediمشاهده پروفایل

استادیار

• Brain Immunology
• Neuro-Immune Interactions
• Macrophage Biology
• +۴ مورد دیگر

Prof. Kiavash Movahedi is a tenure-track Assistant Professor in the Department of Biomedical Sciences at Vrije Universiteit Brussel (VUB), Belgium, leading the Brain and Systems Immunology Team. His research focuses on brain macrophage biology, particularly microglia and non-parenchymal macrophages, using cutting-edge single-cell multi-omic analysis, genome engineering, and stem cell technologies. Dr. Movahedi's research interests center on neuro-immune interactions, with emphasis on macrophage heterogeneity in homeostasis and disease. His lab investigates how brain macrophages contribute to neurodegenerative diseases and brain cancer, seeking to develop novel macrophage-targeted therapies. Key methodologies include single-cell genomics , in vivo imaging , and genetic manipulation models to uncover fundamental mechanisms of neuroinflammation. Analysis of his 15 most recent publications reveals consistent focus on macrophage ontogeny , neuroinflammatory regulation , and tumor microenvironment dynamics , primarily published in high-impact journals like Nature Neuroscience and Immunity . His work demonstrates strong international collaboration across European and US institutions. Scientific Awards: Research Foundation Flanders (FWO) Fellowship during PhD Alexander Von Humboldt Postdoctoral Fellowship Attract Brains to Brussels Program Award Collen-Francqui Research Professorship Dr. Movahedi advises multiple PhD students and postdoctoral researchers in his lab, with current projects funded through VUB institutional support and competitive grants. His research bridges basic immunology and translational neuroscience, with therapeutic implications for Alzheimer's disease, multiple sclerosis, and glioblastoma. The lab maintains strong collaborations with the Max Planck Institute and clinical partners at Brussels Health Campus. Operating within VUB's advanced research infrastructure, the Movahedi lab utilizes state-of-the-art single-cell sequencing facilities and in vivo imaging platforms. The team participates in the broader neuroimmunology network at Brussels Health Campus, contributing to interdisciplinary initiatives targeting neurodegenerative disorders.

Tomas Björklundمشاهده پروفایل

استاد

• Gene Therapy
• Parkinson's Disease
• Molecular Biology
• +۴ مورد دیگر

Professor Tomas Björklund is a faculty member at Lund University, affiliated with the Faculty of Engineering (LTH) and the MultiPark research initiative focused on Parkinson's disease. His research integrates molecular biology, biotechnology, and advanced machine learning to develop therapies for neurological disorders, particularly Parkinson's disease and glioblastomas. He leads projects such as BainSPACE and NSC-Reconstruct, aiming to translate research into clinical applications through partnerships with biotech companies and pharmaceutical industries. He has founded four biotech companies and actively collaborates on projects funded by organizations like Hjärnfonden and the European Commission's Horizon 2020. His work emphasizes spatial sequencing, stem cell organoids, and engineered AAV vectors tailored for precise cellular targeting. He advocates for entrepreneurship to accelerate therapy development, ensuring research outcomes reach clinical settings efficiently. His research aligns with UN Sustainable Development Goals, particularly in advancing health and well-being. Björklund oversees a dynamic research group that combines invention, interdisciplinary collaboration, and translational medicine. His contributions include pioneering spatial sequencing and viral vector engineering, with 52 publications and five active or recent projects. He mentors students in cutting-edge methodologies and drives initiatives to map neural circuits and improve gene therapy efficacy.

Thomas Franz Erich Willnowمشاهده پروفایل

استاد

• Alzheimer’s Disease
• Metabolic Disorders
• Neurodegeneration
• +۳ مورد دیگر

Professor Thomas Willnow leads research groups at Aarhus University and the Max-Delbrück-Center (MDC) in Berlin, focusing on the metabolic basis of neurodegeneration. His work integrates human genetics, mouse models, and iPSC-derived systems to study Alzheimer’s disease and metabolic disorders. Key projects include elucidating VPS10P domain receptors’ roles in lipid metabolism and neuronal viability, with translational goals for dementia therapies. Research emphasizes SORLA, sortilin, and SORCS2 receptors linking systemic metabolism to neurodegeneration. Collaborations include the Novo Nordisk Foundation-funded project exploring AD’s metabolic origins. Willnow’s team also investigates ApoE4’s role in Alzheimer’s risk and lipid homeostasis mechanisms. Affiliations: Department of Biomedicine, Aarhus University; MDC Berlin Key Projects: Alzheimer’s metabolic pathways, SORLA exosome regulation, ApoE3/neuroprotection Grants: €7M Novo Nordisk, BMBF BioRescue, Alzheimer Forschung Initiative Publications span high-impact journals like Nature Communications , EMBO Reports , and Science , with focus on receptors’ therapeutic potential and disease mechanisms. Willnow’s work bridges basic science and clinical translation, addressing global health challenges in aging populations.

Benedetta Leunerمشاهده پروفایل

دانشیار

• Maternal Brain and Behavior
• Neuroimmunology
• Hormonal Contraceptives
• +۳ مورد دیگر

Dr. Benedetta Leuner is an Associate Professor in the Department of Psychology at The Ohio State University. Her research focuses on the female brain, particularly maternal brain plasticity and postpartum mental health. She investigates neuroimmune interactions during pregnancy and postpartum, the impact of stress and opioids on maternal behavior, and hormonal contraceptives' effects on adolescent brain development. Education: PhD in Biopsychology and Behavioral Neuroscience, Rutgers University, 2005 MS in Biopsychology, Rutgers University, 2003 BA in Behavioral Neuroscience, Lehigh University, 1997 Research Interests: Neuroimmune changes in the maternal brain Postpartum depression mechanisms Effects of opioids and hormonal contraceptives Role of microglia in maternal care Recent Article Trends: Her work emphasizes translational models linking neuroimmune systems to maternal behavior and mental health. Recent studies explore opioid exposure in pregnancy, microglia depletion effects, and hormonal contraceptive impacts on adolescent brain regions like the prefrontal cortex. Awards: 2020 Fred Brown Research Award NARSAD Young Investigator Award (2008) Nominee for Distinguished Undergraduate Mentor Award (2015, 2016) Advising & Grants: Supervises graduate students (e.g., Rachel Gilfarb, Courtney Dye) and undergraduates. Funded by NIH, NSF, Brain & Behavior Research Foundation, and OSU initiatives. Collaborates with Dr. Katy Lenz on hormonal contraceptive studies. Labs & Teams: Directs the Leuner Lab, focusing on preclinical studies of female brain health. Collaborations include the Lenz Lab and institutions like the Eunice Kennedy Shriver NICHD.

• Neurodegenerative Diseases
• Epigenetics
• Alzheimer's Disease
• +۵ مورد دیگر

Diego Mastroeni is a Research Associate Professor at Arizona State University (ASU), affiliated with the ASU-Banner Neurodegenerative Disease Research Center and the Biodesign Institute. His work focuses on neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s, with a strong emphasis on epigenetics, mitochondrial dysfunction, and microglial biology. He holds a PhD in Neuroscience from Maastricht University and conducted postdoctoral training at the Banner Sun Health Research Institute. Research Interests: Epigenetic mechanisms in neurodegeneration Microglial and neuronal heterogeneity Single-cell transcriptomics Alzheimer’s disease biomarkers Age-related neurodegeneration Key Projects: Ongoing Alzheimer’s Association grant (2018–2021): Investigating gender effects in Alzheimer’s cell populations NOMIS Foundation-funded project (2018–2023): Creating a public resource of brain cell RNA sequencing data EU JPND Research initiative (2017–2021): Targeting epigenetic dysregulation in Alzheimer’s Publications: Over 40 peer-reviewed articles, including seminal work on DNA methylation in Alzheimer’s and laser capture microdissection techniques. Recent focus on microglial transcriptomics and novel therapeutic targets. Teaching: Involvement in undergraduate research courses (e.g., BCH 392, BIO 495) emphasizing research techniques and honors thesis supervision.

Nathan A. Smithمشاهده پروفایل

دانشیار

• Neuro-Glia Interactions
• Neuromodulation
• Neuroscience
• +۴ مورد دیگر

Nathan A. Smith is an Associate Professor of Neuroscience and Associate Dean for Research Mentorship at the University of Rochester School of Medicine and Dentistry. He holds administrative roles in the Dean's Office and leads the 'Science of Neuro-Glia Interaction' laboratory. His research focuses on neuromodulator-mediated interactions between neurons, astrocytes, and microglia in health and disease, particularly in ADHD, epilepsy, and insulin resistance. Dr. Smith earned his B.S. in Biology from Xavier University (2002) and M.S./Ph.D. in Neuroscience from the University of Rochester (2010/2013). His postdoctoral training included positions at the University of Utah (2013-2015), Boston University, and Children's National Hospital. He is a 2021 AAAS Fellow and has been recognized for advancing diversity in neuroscience. Education: Bachelor of Science, Biology - Xavier University of Louisiana (2002) MS, Neuroscience - University of Rochester School of Medicine & Dentistry (2010) PhD, Neuroscience - University of Rochester School of Medicine & Dentistry (2013) Research Interests: Dr. Smith investigates how neuromodulators like norepinephrine regulate neuro-glial interactions. His lab employs transgenic models, electrophysiology, and imaging techniques to study astrocyte roles in synaptic plasticity and disease. Current projects explore astrocytic lipid release in epilepsy and the role of locus coeruleus in memory formation. Key Achievements: Recipient of 2021 AAAS Fellowship 2020 Cell Press '1000 Inspiring Black Scientists' 2019 University of Rochester Neuroscience Alumni Award 2018 Children's National President's Award for Innovation Advising & Grants: Dr. Smith mentors postdoctoral fellows and graduate students in the Neuroscience PhD and Medical Scientist Training programs. His grants include NIH, NSF, and DOD funding for projects on neuro-glial crosstalk and biomarker identification in neurological disorders. He advocates for DEI initiatives, co-authoring strategies for inclusive labs and journals. Lab & Collaborations: The Smith Lab is affiliated with the Del Monte Institute for Neuroscience and collaborates with institutions like Children's National Research Institute. Ongoing projects include studying astrocyte modulation of sensory transmission and developing tools for mitochondrial research.