جستجوی استاد راهنمای دانشگاهی

Matthew Kimberمشاهده پروفایل

استاد

• Structural Biology
• Bacterial Systems
• Biochemistry
• +۳ مورد دیگر

Dr. Matthew Kimber is a Professor in the Department of Molecular and Cellular Biology at the University of Guelph. His research focuses on structural biology of bacterial systems, particularly bacterial polysaccharides and microcompartments. He employs x-ray crystallography to study molecular architectures, with current projects exploring mechanisms of bacterial surface polysaccharide assembly and bacterial microcompartment function. Education: B.Sc. (Hons) Molecular Genetics and Molecular Cell Biology from the University of Toronto (1993), Ph.D. in Molecular and Medical Genetics from the University of Toronto (2000). Research Interests: Structural basis of polysaccharide assembly and modification, bacterial microcompartment structure-function relationships, and enzyme mechanisms. Key projects include studies on glycosyltransferases, carboxysomes, and aminoacetone degradation pathways. Lab Members: Current graduate students include Laura Seidel, Liam Noseworthy, Manitabhai Govind, and Shaoqian Zong. Former members include Patrick Ryan, Evan Mallette, and Tom Keeling. Lab Focus: Probing structural details of biological molecules to understand function, with emphasis on bacteria’s strategies for polysaccharide modification and microcompartment assembly. Recent work includes characterization of enzymes involved in O-antigen biosynthesis and microcompartment shell proteins.

Michael Feigمشاهده پروفایل

استاد

• Molecular Dynamics
• Computational Biophysics
• Protein Structure and Dynamics
• +۳ مورد دیگر

Michael Feig serves as Professor in the Department of Biochemistry & Molecular Biology at Michigan State University, leading the Feig Lab within the BioMolecular Science Gateway initiative. His research bridges computational modeling and molecular biology to investigate protein behavior in cellular contexts, with particular emphasis on molecular dynamics simulations and machine learning applications. His academic background includes: Ph.D. (1999) from the University of Houston M.S. (1994) from Technical University of Berlin Feig's research program focuses on computational biophysics of protein systems, specializing in molecular dynamics simulations of crowded cellular environments, bacterial microcompartments, and intrinsically disordered proteins. His lab develops advanced modeling techniques including coarse-grained approaches (COCOMO2) and machine learning frameworks to predict protein properties and conformational landscapes. Current work explores temperature-dependent structural ensembles, enzyme cargo loading mechanisms in engineered microcompartments, and biomolecular condensate physics under shear flow. Analysis of his 15 most recent publications (2024-2025) reveals three dominant research thrusts: (1) integration of deep learning with molecular dynamics for protein structure prediction, (2) engineering of bacterial microcompartments for synthetic biology applications, and (3) fundamental studies of macromolecular crowding effects on diffusion and phase separation. His work consistently emphasizes methodological innovation with biological relevance, notably through enhancements to the CHARMM simulation platform. His scientific recognition includes: Alfred P. Sloan Fellowship (2005) As principal investigator of the Feig Lab, he directs research teams in computational biophysics projects supported by active funding mechanisms. While specific grant details aren't provided, his continuous publication pipeline and lab infrastructure indicate sustained research support. His mentorship spans graduate students in the Cell & Molecular Biology Program, with recent work involving multi-institutional collaborations on bacterial microcompartment engineering and protein phase separation. The Feig Lab operates at the intersection of high-performance computing and molecular biology, maintaining strong connections with experimental groups for method validation. Current initiatives include developing generative models for temperature-dependent protein conformations and investigating cytoplasmic protein capture mechanisms in microcompartments, with potential applications in metabolic engineering and nanobiotechnology.

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +۵ مورد دیگر

João F. Mano is a Full Professor at the Department of Chemistry, University of Aveiro, and Director of the Doctoral Program on Biotechnology. He leads the COMPASS Research Group and serves as Vice-Director at CICECO - Aveiro Institute of Materials. His academic appointments include Invited Professor at University of Lorraine (France), Visiting Professor at KAIST (South Korea), and Adjunct Professor at Ajou University (South Korea). Education: PhD in Chemistry (1996, Technical University of Lisbon); D.Sc. in Tissue Engineering, Regenerative Medicine and Stem Cells (2012, University of Minho) Research Interests focus on Biomaterials for Regenerative Medicine , integrating Nanotechnology , Microtechnology , and Biofabrication . His group develops Bioinspired Materials using polymer chemistry, Decellularized Extracellular Matrix , and 3D Bioprinting to engineer Cell Microenvironments for therapeutic applications. Recent Publications highlight advancements in Human-Derived Hydrogels , Photopolymerizable Scaffolds , Magneto-Responsive Biomaterials , and Programmable Bioinks . Trends show emphasis on Organ-on-a-Chip integration, Smart Living Materials , and Green Bioprinting methodologies. Scientific Awards include: European Research Council Advanced Grants (2015, 2020) Fellow at IUPAC, European Academy of Sciences, and American Institute of Medical and Biological Engineering ERC Proof of Concept Grants Doctor Honoris Causa from University of Lorraine and Utrecht UNESCO Chair on Biomaterials George Winter Award (European Society for Biomaterials) Supervisions & Collaborations encompass 74+ MSc, 26+ PhD students, and 40+ postdocs. He co-founded METATISSUE and CELLULARIS Biomodels , and serves as Editor-in-Chief of Materials Today Bio .

Anders Sejr Hansenمشاهده پروفایل

استادیار

• 3D Genome Structure
• Gene Expression Regulation
• Chromatin Dynamics
• +۵ مورد دیگر

Anders Sejr Hansen is an Assistant Professor of Biological Engineering at MIT, leading the Hansen Lab focused on understanding 3D genome structure and its functional implications. He holds a PhD from Harvard University and completed postdoctoral training at UC Berkeley. His research integrates advanced imaging, genomics, and computational methods to study chromatin dynamics, enhancer-promoter interactions, and their roles in gene regulation across health and disease. Education: Bachelor's/Master's in Chemistry, University of Oxford (2010) PhD in Chemistry and Chemical Biology, Harvard University (2015) Postdoctoral Research, UC Berkeley (2015–2020) Research Interests: His work spans molecular mechanisms of genome organization, development of novel microscopy techniques (e.g., MINFLUX, expansion microscopy), and computational models for 3D genomics. Key areas include chromatin dynamics, loop extrusion by cohesin/condensin, and the impact of 3D structure on gene expression in cancer and aging. Awards: NIH K99 Pathway to Independence Award (2019) NIH Director’s New Innovator Award (2020) Pew-Stewart Scholar for Cancer Research (2021) NSF CAREER Award (2024) NIH Director’s Transformative Research Award (2024) Advising & Grants: Hansen mentors PhD students and postdocs, including notable advisees Viraat Goel and Domenic Narducci. His lab has secured major grants from NIH, NSF, and private foundations, supporting interdisciplinary projects in imaging, genomics, and synthetic biology. Labs/Teams: The Hansen Lab at MIT collaborates with institutions globally, advancing technologies like Region Capture Micro-C (RCMC) and deep learning models (e.g., Cleopatra) for high-resolution genome mapping. The lab also explores synthetic biology approaches to engineer genome structures.

Monica Olvera de la Cruzمشاهده پروفایل

استاد

• Polymer Science
• Soft Materials
• Condensed Matter Physics
• +۵ مورد دیگر

Monica Olvera de la Cruz is the Lawyer Taylor Professor of Materials Science and Engineering, Chemistry, and Chemical & Biological Engineering at Northwestern University, with a courtesy appointment in Physics and Astronomy. She directs the Center for Computation & Theory of Soft Materials and serves as Deputy Director of the Center for Bio-Inspired Energy Science. Her research focuses on designing responsive materials, including polymers, electrolytes, and complex fluids, with applications in biotechnology and energy. She holds a Ph.D. from Cambridge University (1985) and a B.A. from UNAM (Mexico). Her research interests include self-assembly of heterogeneous molecules, ionic-driven assembly mechanisms, and functional materials design. Recent work highlights include modeling electrostatic effects in biomimetic systems and exploring superionic conductors. Awards include National Academy of Sciences membership (2012), APS Polymer Prize (2017), and American Philosophical Society membership (2020). Professional service roles: Gordon Research Conferences Board, DOE Basic Energy Sciences, Max Planck Institute advisory board Led over 150 publications since 2020, emphasizing soft matter physics and materials innovation Her group's innovations bridge theoretical physics and applied materials science, with notable achievements in bio-inspired materials and electrochemical systems.

Jan C.M. van Hestمشاهده پروفایل

استاد

• Bio-inspired Materials
• Nanomedicine
• Artificial Cells
• +۳ مورد دیگر

Jan C.M. van Hest is a Full Professor at Eindhoven University of Technology (TU/e), holding positions in the Department of Chemical Engineering and Chemistry and the Institute for Complex Molecular Systems (ICMS) . He leads research at the intersection of polymer chemistry and biomedicine, focusing on bio-inspired materials, nanomedicine, and artificial cells. His work includes developing synthetic vaccines, drug delivery systems, and adaptive nano/microcompartments mimicking cellular functions. Academic Background : Ph.D. in macro-organic chemistry from TU/e (1996), postdoc at the University of Massachusetts (protein engineering), and industry roles at DSM (1997–2000). Since 2016, he has held the Bio-organic Chemistry chair at TU/e, supervising over 30 PhD students and co-founding startups like Encapson and Noviosense. Research Highlights : His research spans nanomedicine (e.g., polymersomes for cancer treatment) and artificial cells (e.g., synthetic organelles). Recent work includes therapeutic nanovaccines and self-propelled platinum-loaded stomatocytes. His publications span Nature Nanotechnology , Nature Chemistry , and Angewandte Chemie . Awards & Collaborations : Recipient of the ERC Advanced Grant (2015) and NWO Gravitation Grant (2013). Partnerships with GSK, Zoetis, and industry initiatives like the TKI-LSH EUREKA project. Engages in education through courses like Biochemistry and Introduction to Chemistry & Chemical Technology. Labs & Teams : Core member of ICMS, leading interdisciplinary projects in functional molecular systems. Active in training the next generation of researchers through postgraduate programs like ICMS PTN.

• Molecular Biology
• Cell Biology
• Autophagy
• +۳ مورد دیگر

Prof. Dr. Christian Ungermann is a Professor in the Department of Biochemistry at the University of Osnabrück, Germany. His research focuses on the molecular mechanisms underlying endosome, lysosome, and autophagosome biogenesis. He combines cell biological methods with in vitro reconstitution assays to study protein complexes involved in these processes. His work is critical for understanding disease-related mechanisms linked to organelle dysfunction. Research topics include endosomal maturation, autophagosome/lysosome biogenesis, and endosomal signal transduction. Model systems include Saccharomyces cerevisiae, insect cells, and Drosophila melanogaster. Key methods are protein purification, fluorescence microscopy, membrane fusion assays, and enzymatic activity assays. Recent publications highlight studies on Rab GTPase regulation, endosomal Rab transitions, and CORVET tethering complex structure, reflecting expertise in membrane trafficking and organelle dynamics.

Michael Haganمشاهده پروفایل

استاد

• Biophysics
• Soft Condensed Matter
• Active Matter
• +۴ مورد دیگر

Michael Hagan is a Professor of Physics at Brandeis University, affiliated with the Martin A. Fisher School of Physics. His research focuses on understanding the physical principles governing assembly and dynamic organization in biological and biomimetic systems. He employs computational and theoretical methods, including machine learning, to study viral capsid assembly, bacterial microcompartments, and active matter systems. His work bridges length and time scales to elucidate emergent behaviors in nonequilibrium systems. Education: PhD in Physics from the University of California, Berkeley (2003). His group, the Hagan Lab, collaborates with experimentalists and has received funding from the DOE, NSF, Keck Foundation, and NIH. Key areas include viral genome assembly optimization, bacterial microcompartment formation, and the dynamics of active nematics. Recent studies explore defect-ordered phases, phase separation in active colloids, and programmable self-assembly of geometric structures. Research interests span biophysics, soft condensed matter, and computational modeling. His lab's work has implications for synthetic biology, drug design, and material science. Collaborations with experimental groups (e.g., Z. Dogic's lab) have led to discoveries in active matter dynamics and biomimetic systems.

Carolyn Millsمشاهده پروفایل

استادیار

• Protein Engineering
• Systems Biology
• Synthetic Biology
• +۴ مورد دیگر

Carolyn Mills is an Assistant Professor in the Department of Bioengineering at the University of California, Santa Barbara, specializing in molecular engineering of proteins for spatial organization in biological systems with applications in plastic remediation and oral vaccine delivery. Education: PhD, Chemical Engineering, Massachusetts Institute of Technology (MIT) BS, Chemical Engineering, UC Santa Barbara Her research integrates protein engineering, synthetic biology, and polymer science to manipulate spatial organization. Key focus areas include bacterial microcompartments for PET waste remediation, liquid-liquid phase separation characterization using cell-free systems, anaerobic platforms for lignin breakdown, and probiotic-based oral vaccine delivery using virus-like particles. The Mills Lab employs high-throughput screening and cell-free protein synthesis to develop closed-loop plastic degradation systems and low-cost vaccine scaffolds. Recent publications (2022-2025) demonstrate consistent innovation in protein self-assembly mechanisms, bacterial organelle engineering, and environmental/medical applications, with strong emphasis on scalable solutions for plastic pollution and global vaccine access. Scientific awards: Distinguished Postdoctoral Service Award, Northwestern University Dr. Mills leads collaborative projects with Prof. Michelle O'Malley and ExFAB (UCSB's NSF Biofoundry), focusing on anaerobic fungal pathways. Her lab bridges fundamental protein dynamics with real-world applications in environmental sustainability and biomedical engineering through engineered spatial organization strategies.

Christine Keatingمشاهده پروفایل

استاد

• Astrobiology
• Colloid and Interface Science
• Biophysical Chemistry
• +۶ مورد دیگر

Christine Keating is the Shapiro Professor of Chemistry at Pennsylvania State University's Department of Chemistry. She is affiliated with the Huck Institutes for the Life Sciences and the Materials Research Institute, and serves on the graduate faculty of the Bioengineering Department. Her research focuses on self-assembled artificial cells, prebiotic compartmentalization, bioinspired materials synthesis, and particle assembly. Her work bridges physical chemistry, colloid science, and biological chemistry. Education: B.S. in Biology and Chemistry from Saint Francis College (1991), Ph.D. in Chemistry from Penn State (1997). Research Themes: Artificial cells and cytomimetic chemistry Prebiotic compartmentalization via coacervation Bioinspired materials using phase-separated microenvironments Optical applications of reconfigurable particle assemblies Awards: Over 20 honors including the Langmuir Lectureship (2024), AAAS Fellowship (2014), and NSF CAREER Award (2003-2008). Grants: Active funding includes projects on protocells and Rules of Life collaboration through NSF. Advises graduate students in interdisciplinary programs. Labs: Leads the Keating Group and participates in the ProteoCell Project, a six-university NSF initiative.

E. Thomas (Tommy) Pashuckمشاهده پروفایل

استادیار

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +۶ مورد دیگر

E. Thomas (Tommy) Pashuck is an Assistant Professor in the Department of Bioengineering at Lehigh University , where he joined after postdoctoral training at Rutgers University and Imperial College London . His research focuses on designing enzyme-responsive biomaterials using peptide self-assembly to control hydrogel chemistry and nanoscale organization , aiming to improve regenerative medicine applications. Education: Ph.D. in Materials Science from Northwestern University (2009) Pashuck's work explores biomaterials that direct cell behavior through precise spatial and mechanical cues . Recent publications highlight advancements in high-throughput peptide screening , 4D bioprinting , and protease-activated hydrogels , demonstrating his expertise in dynamic biomaterial design and cell-matrix interactions . His research group investigates cell adhesion optimization via ligand mobility control , enzyme-mimicking nanomaterials , and sequence-controlled polymerization while maintaining clinical translation goals. Publications from 2021-2025 emphasize hydrogel mechanics , biodegradable scaffolds , and supramolecular catalytic systems , spanning biomaterial engineering , peptide nanotechnology , and regenerative medicine .

Sabrina Büttnerمشاهده پروفایل

استاد

• Cellular Aging
• Organelle Communication
• Membrane Contact Sites
• +۵ مورد دیگر

Prof. Sabrina Büttner leads the Cell Biology group at the Institute of Integrative Cell Biology and Physiology, University of Münster. Her research focuses on intracellular communication during cellular aging, stress responses, and metabolic adaptation, utilizing yeast and Drosophila models. She investigates organelle connectivity via membrane contact sites and their role in proteostasis, neurodegeneration, and longevity. Her work integrates molecular biology, genetics, and imaging to explore: Organelle communication networks Proteostasis collapse in aging Autophagy and lipid metabolism Neurodegenerative disease mechanisms Recent publications emphasize membrane contact sites, stress-induced nuclear/vacuole dynamics, and autophagy regulation. Trends include organelle interfaces in proteostasis, mitochondrial quality control, and translational applications in longevity biotechnology. She mentors PhD students including Irene Álvarez-Guerra, Emma Block, Patricia Grabher, and Simon Prokisch. Her lab collaborates with CRC projects (e.g., CRC 1009, 1348, 1459, 944) and graduate programs (CiM-IMPRS, IRTG, SP BioSciences).

Hannes Mutschlerمشاهده پروفایل

استاد

• Synthetic Biology
• Origin of Life
• Ribozyme Engineering
• +۵ مورد دیگر

Prof. Hannes Mutschler is a faculty member at the Faculty of Chemistry and Chemical Biology of Technische Universität Dortmund , leading research in Chemical Biology with a focus on synthetic biology and origin-of-life studies. University: Technische Universität Dortmund School: Faculty of Chemistry and Chemical Biology Department: Chemical Biology Academic Rank: Professor Research interests include: De novo engineering of self-replicating and evolving biomimetic systems Origin of Life studies Ribozyme activity under prebiotically plausible conditions Bottom-up approaches using reconstituted protein/nucleic acid components Design of complex protein machineries and ribozymes Publication trends : Recent work explores ribozyme engineering for DNA/RNA catalysis Investigates RNA replication in prebiotic environments Develops synthetic RNA segregation systems Examines temperature-driven RNA proliferation in vesicles Focus on active droplets and coacervates as protocell models Contact: hannes.mutschler@tu-dortmund.de

• Microbiology
• Bacterial Pathogenesis
• Infection Biology
• +۳ مورد دیگر

Mr. Damien BALESTRINO is a Senior Lecturer affiliated with the Faculty of Pharmacy (Faculté de Pharmacie) at Université Clermont Auvergne (UCA). His research focuses on bacterial pathogenesis, particularly Klebsiella pneumoniae's structural biology and infection mechanisms. He is part of the LMGE UMR CNRS6023 research unit's CMES team based in Clermont-Ferrand. Recent work includes studies on bacterial microcompartment protein interactions and biofilm regulation. His publications analyze structural protein compatibilities, membrane lipid regulation in biofilms, and murine models of Klebsiella infection dissemination. Key contributions involve understanding Klebsiella's adaptive strategies and virulence mechanisms. Institution: Université Clermont Auvergne (UCA) Affiliation: Faculty of Pharmacy Team: CMES Team (LMGE UMR CNRS6023) Research emphasizes structural microbiology and infection biology with applications to antimicrobial resistance. His articles demonstrate interdisciplinary approaches combining structural biology, microbiology, and immunology to address bacterial pathogenesis challenges.

Darko Stefanovicمشاهده پروفایل

استاد

• Programming Languages
• Molecular Computing
• Scientific Simulations
• +۳ مورد دیگر

Darko Stefanovic is a Professor of Computer Science (and courtesy faculty in Chemical & Biological Engineering) at the University of New Mexico. He has been continuously active in teaching and research since at least 2000, with a focus on programming languages, molecular computing, and scientific simulations. University: University of New Mexico Department: Department of Computer Science Academic Rank: Professor His research interests span molecular computing , DNA nanotechnology , and synthetic biology , with recent publications exploring applications in artificial β-cells , heterochiral translators , and reservoir computing with chemical systems . Many publications involve collaborations with researchers in biochemistry, nanotechnology, and systems biology. Teaching activities include numerous offerings of courses such as Compiler Construction , Programming Paradigms , Software Foundations , and Algorithms and Data Structures at both undergraduate and graduate levels. Course materials often emphasize functional programming (e.g., Standard ML), λ-calculus, and logic programming implementations. Recent publications (2025–2019) demonstrate ongoing work in molecular robotics , DNA-based computation , and synthetic cell engineering . These works frequently appear in venues related to biomolecular computing , nanotechnology , and synthetic biology . Teaching Career spans multiple decades at UNM, covering topics from foundational programming to advanced compiler construction. Course materials show emphasis on formal methods, programming language theory, and computational models, including implementations of λ-calculus interpreters and Prolog systems.