Matthew Kimber

Dr. Matthew Kimber is a Professor in the Department of Molecular and Cellular Biology at the University of Guelph. His research focuses on structural biology of bacterial systems, particularly bacterial polysaccharides and microcompartments. He employs x-ray crystallography to study molecular architectures, with current projects exploring mechanisms of bacterial surface polysaccharide assembly and bacterial microcompartment function.

Education: B.Sc. (Hons) Molecular Genetics and Molecular Cell Biology from the University of Toronto (1993), Ph.D. in Molecular and Medical Genetics from the University of Toronto (2000).

Research Interests: Structural basis of polysaccharide assembly and modification, bacterial microcompartment structure-function relationships, and enzyme mechanisms. Key projects include studies on glycosyltransferases, carboxysomes, and aminoacetone degradation pathways.

Lab Members: Current graduate students include Laura Seidel, Liam Noseworthy, Manitabhai Govind, and Shaoqian Zong. Former members include Patrick Ryan, Evan Mallette, and Tom Keeling.

Lab Focus: Probing structural details of biological molecules to understand function, with emphasis on bacteria’s strategies for polysaccharide modification and microcompartment assembly. Recent work includes characterization of enzymes involved in O-antigen biosynthesis and microcompartment shell proteins.