معرفی
Dr. Chenguang Fan is an Associate Professor in the Department of Chemistry & Biochemistry at the University of Arkansas, College of Arts & Sciences. He earned his BS in Biological Pharmacy from Nanjing University, PhD in Biochemistry from Iowa State University under Professor Thomas Bobik, and conducted postdoctoral research with Professor Dieter Söll at Yale University.
- Research Interests: Protein chemistry, bacterial pathogenesis, cancer biology, and synthetic biology using genetic code expansion techniques.
- Key Techniques: Development of noncanonical amino acid incorporation systems, site-specific acetylation studies in Escherichia coli, and engineering bacterial microcompartments.
- Teaching: Offers undergraduate and graduate courses in chemistry and biochemistry.
Dr. Fan's work spans interdisciplinary approaches to study post-translational modifications, particularly lysine acetylation, in metabolic enzymes and bacterial pathogens. His group focuses on:
- Mapping protein-protein interaction networks
- Developing tools for noncanonical amino acid labeling
- Designing inhibitors for Salmonella metabolic organelles
- Engineering bacterial microcompartments as nano-bioreactors for biofuels
- Investigating cancer-related phosphorylation and acetylation
His publications highlight contributions to genetic code expansion, enzyme encapsulation in metal-organic frameworks, and functional analysis of bacterial microcompartments. Notable awards include the Ralph E. Powe Junior Faculty Enhancement Award and Arkansas Biosciences Institute New Investigator of the Year 2018. Dr. Fan has received NIH grants from NIAID and NIGMS to support his research.
