معرفی
Prof. Sabrina Büttner leads the Cell Biology group at the Institute of Integrative Cell Biology and Physiology, University of Münster. Her research focuses on intracellular communication during cellular aging, stress responses, and metabolic adaptation, utilizing yeast and Drosophila models. She investigates organelle connectivity via membrane contact sites and their role in proteostasis, neurodegeneration, and longevity.
Her work integrates molecular biology, genetics, and imaging to explore:
- Organelle communication networks
- Proteostasis collapse in aging
- Autophagy and lipid metabolism
- Neurodegenerative disease mechanisms
Recent publications emphasize membrane contact sites, stress-induced nuclear/vacuole dynamics, and autophagy regulation. Trends include organelle interfaces in proteostasis, mitochondrial quality control, and translational applications in longevity biotechnology.
She mentors PhD students including Irene Álvarez-Guerra, Emma Block, Patricia Grabher, and Simon Prokisch. Her lab collaborates with CRC projects (e.g., CRC 1009, 1348, 1459, 944) and graduate programs (CiM-IMPRS, IRTG, SP BioSciences).
