جست‌وجوی استاد و پژوهشگر

• Physiology
• Molecular Medicine
• Chronic Diseases
• +۳ مورد دیگر

Marcos Fernandez Fondevila is a researcher specializing in Physiology at the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) within the University of Santiago de Compostela . He is affiliated with the GIBIOMED Biomedical Research Group, focusing on liver diseases and metabolic disorders. Education : PhD in Medicine from the University of Santiago de Compostela (2021), with a thesis on the role of the L-α-lysophosphatidylinositol/GPR55 system in non-alcoholic steatosis and steatohepatitis. Research Interests center on: Molecular mechanisms of steatotic liver disease (NASH/MASLD) Gut microbiota-liver axis interactions Role of protein modifications (e.g., NEDDylation, O-GlcNAcylation) in metabolic regulation Intestinal barrier function in alcohol-related liver disease Signaling pathways in hepatic fibrosis (p63, TLR4, HER2) Neutrophil-mediated inflammation in hepatitis Research Trends from recent publications reveal a focus on alcohol-associated liver disease , metabolic dysregulation , and gut-liver axis dynamics . His work explores NEDDylation in aging, intestinal retroviruses in liver pathology, and microbial metabolites as disease drivers.

Guy Jacobsمشاهده پروفایل

پژوهشگر ارشد

• Evolutionary genetics
• Population genetics
• Human evolutionary biology
• +۱۲ مورد دیگر

Guy Jacobs is a Research Fellow at the University of Cambridge, Department of Archaeology, specializing in evolutionary genetics and microbiome ecology. His work combines large-scale genomic datasets with computational modeling to investigate human evolutionary history, archaic hominin interactions, and microbiome dynamics during subsistence transitions in traditionally hunter-gatherer communities across India and Indonesia. Primary focus on population genetics, human adaptation, and social network impacts Expertise in computational modeling of evolutionary processes Collaborations with C-CLEAR DTP and CREATES partnerships Research spans ancient DNA analysis, archaic introgression patterns, and the interplay between genetic ancestry, environment, and health outcomes. Key projects include studies of Denisovan ancestry in Island Southeast Asia, microbiome differentiation in lifestyle transitions, and sociocultural influences on genetic diversity. Recent publications highlight trends in human adaptation to malaria and high-altitude environments, microbiome evolution during urbanization, and computational methods for detecting selective sweeps. His work integrates genomic data with social and environmental variables to address questions in biological diversity and human phenotypic variation. As part of the Cambridge NERC Doctoral Landscape Awards, he supervises students on topics ranging from archaic introgression analysis to genetic disease mapping. He utilizes datasets from Indonesia, India, and the Indonesian archipelago, combining genetic, transcriptomic, and mobility data in his research.

Michael Inouyeمشاهده پروفایل

استاد

• Systems Genomics
• Cardiovascular Disease
• Population Health
• +۳ مورد دیگر

Professor Michael Inouye is a leading systems genomics and population health researcher at the University of Cambridge (Department of Public Health and Primary Care) and Baker Heart & Diabetes Institute (Melbourne). His work bridges statistical genetics, computational biology, and clinical translation, with a focus on cardiovascular/respiratory diseases and sustainable research practices. Director of Research (Research Professor) since 2021 Honorary Professorial Fellow at University of Melbourne since 2021 Co-leader of Cambridge Baker Systems Genomics Initiative since 2017 Research Interests include: Polygenic risk score development and clinical implementation Multi-omic integration (genomics, proteomics, microbiomics) Host-microbiome interactions in disease Sustainable computational methodologies Cardiometabolic disease prevention Scientific Contributions show leadership in: Developing the Polygenic Score Catalog infrastructure Creating environmentally sustainable algorithmic frameworks Elucidating microbiome contributions to chronic diseases Advancing multi-modal risk prediction models Integrating genetic and metabolic pathway analysis Recent Publications demonstrate expertise across: Polygenic score optimization for blood traits and diabetes Microbiome-disease interaction networks Computational sustainability in biomedical research Cardiovascular risk stratification Multi-omic data harmonization Genetic determinants of molecular phenotypes

Alexandre Almeidaمشاهده پروفایل

پژوهشگر ارشد

• Human microbiome
• Metagenomics
• Bioinformatics
• +۴ مورد دیگر

Alexandre Almeida is a Research Fellow in the Department of Veterinary Medicine at the University of Cambridge, affiliated with the School of Biological Sciences. His research focuses on metagenomic analysis of the human gut microbiome, particularly uncultured microbial species across multiple kingdoms. Educational background: PhD in Microbiology from Institut Pasteur Current affiliations: Cambridge Infectious Diseases group Research Themes His work addresses fundamental questions about: Role of uncultured microbiome in aging and neurodegeneration Pathogen colonization mechanisms Multi-kingdom interactions in human microbiota Biomedical applications of microbiome biomarkers Scientific Contributions Key achievements include: Tripling known gut bacterial diversity through MAGs Leading discovery of 140,000 novel gut viruses Developing improved reference databases for metagenomic analysis Awards and Recognition EBI-Sanger Postdoctoral Fellowship MRC Career Development Award Academic Service His group accepts PhD students and maintains active collaboration with: Dr Lucy Weinert Professor Cinzia Cantacessi Professor Julian Parkhill Professor Mark Holmes Technological Impact Developed widely used resources: GitHub repositories for microbiome analysis Comprehensive gut microbiome reference catalog

Daniel Schultzمشاهده پروفایل

دانشیار

• Systems Biology
• Antibiotic Resistance
• Gene Regulatory Networks
• +۵ مورد دیگر

Daniel Schultz is an Associate Professor at the Geisel School of Medicine at Dartmouth College , where he holds the John G. Kemeny Professorship in the Neukom 1964 Academic Cluster in Computational Science. His research focuses on quantitative approaches to gene networks in bacteria, particularly antibiotic resistance mechanisms . Education: PhD in Chemistry & Biochemistry (UC San Diego), Engineering in Electronics Engineering (ITA) His work combines mathematical modeling, bioinformatics, experimental evolution , and microfluidics to study bacterial responses to environmental stressors. He investigates how gene regulatory circuits coordinate cellular processes, how antibiotic resistance evolves in clinical environments, and how microbial communities reorganize under environmental changes. Scientific contributions include: Decoding dynamic gene regulation in antibiotic resistance Modeling fitness landscapes for bacterial evolution Developing predictive models for microbial community behavior His lab reveals evolutionary trade-offs between resistance costs and benefits , showing how mobile genetic elements and repression mechanisms optimize bacterial survival. He also explores stochastic gene expression as a driver of phenotypic diversity. Scientific awards: John G. Kemeny Professorship (Neukom 1964 Cluster) Teaching: Course: Introduction to Quantitative Biology

• Bioinformatics
• Microbiota Analysis
• Inflammatory Bowel Disease
• +۳ مورد دیگر

Marcus Claesson is a Lecturer in the Department of Microbiology at University College Cork (UCC), Ireland. He is also a Principal Investigator and Funded Investigator at the Alimentary Pharmabiotic Center, managing the BioIT platform. His research focuses on microbiota analysis, particularly in inflammatory bowel disease (IBD) and the gut microbiome of elderly Irish subjects via metagenomics and 'omics' methods. Education: BSc in Chemical Engineering, Chalmers University of Technology MSc in Bioinformatics, Chalmers University of Technology PhD in Bioinformatics, University College Cork Marcus specializes in bioinformatics method development for analyzing gut microbiota composition and function. His work includes the ELDERMET project (metagenomic analysis of elderly microbiomes) and sequencing Lactobacillus salivarius and Bifidobacteria to identify probiotic traits. He has explored the role of flagellin proteins in inflammation and the impact of antibiotics on elderly microbiota. His peer-reviewed publications (15 most recent) reflect a strong focus on microbiome analysis , metagenomics , and probiotic discovery , with applications in human health and microbial ecology . Scientific Awards: UCC Early Stage Researcher of the Year (2012) Alimentary Pharmabiotic Centre Young Scientist of the Year (2010) Bioscience Institute PhD Student of the Year (2007) Marcus supervises doctoral students in microbiome research and teaches modules including Computational Biology , Computational Systems Biology , and Genomic Data Analysis . He coordinates the MSc program in Bioinformatics and Computational Biology.

• Hepatology
• Non-Alcoholic Fatty Liver Disease (NAFLD)
• Alcoholic Liver Disease
• +۷ مورد دیگر

Professor Chris Day is a leading academic at Newcastle University , with a focus on liver diseases, particularly non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. His research spans genetics, biomarker discovery, and lifestyle interventions, often involving international collaborations. Affiliation: Newcastle University Academic Rank: Professor Research Interests: Professor Day investigates the genetic and environmental factors driving liver disease progression, including inflammation, fibrosis, and cardiometabolic complications. His work emphasizes the role of polymorphisms (e.g., PNPLA3, TM6SF2), non-invasive diagnostic tools (e.g., FibroTest), and interventions like exercise and dietary modifications. Recent Article Trends: His recent publications analyze genetic risk scores for cirrhosis, lipid metabolism in inflammation, and the impact of aging on fibrosis diagnosis. These studies highlight cross-disciplinary themes in genomics, metabolomics, and clinical epidemiology. Scientific Contributions: Key contributions include validating biomarkers for liver fibrosis, exploring the gut-liver axis in type 2 diabetes, and leading clinical trials on antifibrotic therapies (e.g., losartan). His work bridges translational research and public health applications.

• Demography
• Population Health
• Social Epidemiology
• +۷ مورد دیگر

Professor Jennifer Dowd serves as Professor of Demography and Population Health at the University of Oxford and Deputy Director of the Leverhulme Centre for Demographic Science. Her interdisciplinary work integrates demography, epidemiology, and social science to investigate how socioeconomic factors influence biological processes and health outcomes across the lifespan. Her academic training includes: PhD in Demography and Economics from Princeton University Postdoctoral fellowship as Robert Wood Johnson Health & Society Scholar at University of Michigan Dr. Dowd's research centers on the biological embedding of social inequality, examining how socioeconomic status shapes immune function, infection susceptibility, and chronic disease trajectories in aging populations. She pioneers studies on social determinants of the human microbiome and investigates drivers of stalled life expectancy in high-income nations through her ERC-funded MORTAL project. Her methodological approach combines longitudinal cohort analysis with interdisciplinary frameworks from economics and infectious disease modeling to reveal mechanisms linking social structures to physiological health outcomes. Recent publications (2025) demonstrate consistent focus on life course epidemiology using international cohort data, with emerging themes in pandemic mortality analysis, generational health disparities, and immunological aging. Key methodological strengths include compositional data analysis and cause-of-death decomposition techniques applied across diverse populations from British birth cohorts to 24-country mortality datasets. Scientific recognition includes: ERC Consolidator Grant for MORTAL project Robert Wood Johnson Health & Society Scholar fellowship As Principal Investigator of the €2M ERC Consolidator Grant, Dr. Dowd leads multinational research on US/UK life expectancy stagnation while directing pandemic mortality analysis for global policy. She co-founded 'Those Nerdy Girls'—an all-female science communication collective translating complex health research for public audiences—demonstrating commitment to knowledge mobilization beyond traditional academic channels. Dr. Dowd's research ecosystem spans the Leverhulme Centre for Demographic Science and Nuffield Department of Population Health, where she collaborates with immunologists, economists, and data scientists on projects ranging from microbiome-social interaction studies to real-time pandemic mortality surveillance. Her lab integrates biological sampling with social survey data to develop novel metrics of 'social weathering' in population health.

• Immunology
• Pharmacology
• Inflammation Biology
• +۵ مورد دیگر

Dr. Saskia Overbeek is a Researcher in the Department of Pharmacology within the Faculty of Science at Utrecht University. Her research spans immunology, pharmacology, and nutritional science with a focus on how dietary components modulate immune responses and inflammation. Dr. Overbeek's research interests include: Immune regulation through dietary components Human milk oligosaccharides and immune development Neutrophil biology in inflammatory conditions Gut-lung axis and mucosal immunity Microbiome-immune system interactions Development of nutritional interventions for immune-related disorders Her publication record (2007-2024) demonstrates an evolution from neutrophil biology in respiratory diseases to broader investigations of dietary immunomodulation. Recent work (2018-2024) focuses on how human milk oligosaccharides and other prebiotics influence immune responses, particularly their ability to suppress Th2 responses while enhancing Th1 and regulatory pathways. This research has implications for allergy prevention, vaccine efficacy, and inflammatory conditions. Key scientific contributions: Extensive publication record in high-impact journals including Nature Reviews Nephrology, PLoS One, and Gut Pioneering work on N-acetyl proline-glycine-proline and neutrophil-mediated inflammation Significant contributions to understanding gut-kidney axis in chronic kidney disease Research on how dietary components modulate immune responses in vaccination and allergy contexts Dr. Overbeek has maintained extensive collaborations with researchers at Utrecht University, particularly with colleagues in pharmacology, immunology, and nutritional sciences. Her work typically employs in vitro models using intestinal epithelial cells and immune cells, complemented by murine models to study immune responses in vivo.

Dan Nettletonمشاهده پروفایل

استاد

• Statistical Methods for Biological Data
• Transcriptomics (RNA-seq, Microarrays)
• Genome-Wide Association Studies
• +۵ مورد دیگر

Dan Nettleton is a Professor at Iowa State University 's Department of Statistics , where he serves as the Laurence H. Baker Endowed Chair and Department Chair . His academic career focuses on statistical methods for high-dimensional biological datasets, including transcriptomic data (microarrays, RNA-seq), microbiome data, and genome-wide association studies, with applications in plant and animal sciences. He also contributes to statistical learning methodology and sports analytics. PhD , Statistics, University of Iowa (1996) MS , Statistics, University of Iowa (1993) BA , Mathematics, Wartburg College (1991) Nettleton's research addresses statistical challenges in analyzing complex biological datasets, including methods for genome-wide association studies, RNA-seq analysis, and genotype-by-environment interactions. He applies these methods to problems in plant genetics, microbiome studies, and sports prediction models. His work on random forests and predictive analytics has broad implications in both life sciences and sports statistics. His recent publications highlight interdisciplinary applications of statistics, including RNA-seq methodology, plant phenotyping with CNN models, and sports analytics using conformal prediction. Collaborations with plant and animal scientists underscore his impact on agricultural research and biological systems analysis. Advising : Nettleton actively advises graduate students, serves on doctoral committees, and contributes to student education in statistics and interdisciplinary research. No explicit grants are listed in the provided text. Labs/Teams : Affiliated with the Laurence H. Baker Center for Bioinformatics and Biological Statistics at Iowa State University, integrating computational and biological research.

• Clinical Pharmacology
• Pharmacokinetics
• Drug Interactions
• +۵ مورد دیگر

Staffan Rosenborg is an Adjunct Lecturer and Docent at Karolinska Institutet's Department of Laboratory Medicine, specializing in the Division of Clinical Pharmacology. His work focuses on drug interactions, pharmacokinetics, and therapeutic drug monitoring, with particular expertise in renal pharmacology and clinical laboratory medicine. His educational background includes: Docent (2022) from Karolinska Institutet PhD in Laboratory Medicine (2010) from Karolinska Institutet Medical Degree (1996) from Karolinska Institutet Dr. Rosenborg's research spans multiple areas of clinical pharmacology with a strong emphasis on drug metabolism, therapeutic drug monitoring, and pharmacokinetics. His work frequently examines drug interactions, particularly those involving cytochrome P450 enzymes, and investigates appropriate dosing strategies for patients with renal impairment. He has conducted significant research on antibiotic effects on microbiota, methylphenidate pharmacokinetics in various populations, and ketone body metabolism in older adults. His expertise bridges clinical practice with laboratory medicine, focusing on translating pharmacological research into practical clinical applications. Analysis of his recent publications reveals a consistent focus on pharmacokinetic studies, drug safety, and therapeutic drug monitoring. His work often involves innovative sampling techniques including exhaled breath and oral fluid analysis as alternatives to traditional blood sampling. A significant portion of his research addresses challenges in renal pharmacology, including drug dosing adjustments for patients with kidney impairment. His studies frequently employ crossover trial designs and utilize advanced analytical methods such as LC-MS/MS for precise drug quantification. Dr. Rosenborg has been involved in the development and evaluation of clinical decision support systems like Janusmed Renal Function, which aids in appropriate drug dosing for patients with renal impairment. His work demonstrates a strong commitment to improving medication safety and optimizing pharmacotherapy through evidence-based approaches.

Isabelle R. Miousseمشاهده پروفایل

استادیار

• Cancer Metabolism
• Cancer Epigenetics
• Folate Metabolism
• +۵ مورد دیگر

Isabelle R. Miousse is an Assistant Professor at the University of Arkansas for Medical Sciences (UAMS), affiliated with the College of Medicine and the Department of Biochemistry and Molecular Biology. She is also a member of the Winthrop P. Rockefeller Cancer Institute. Her research focuses on cancer metabolism and epigenetics, particularly the role of methionine in DNA/histone methylation in tumors. She earned her Ph.D. at McGill University, Canada. Research Interests: Cancer metabolism with emphasis on methyl donor pathways (folate, vitamin B12, methionine) Differential methionine utilization in cancer vs. normal cells Methionine restriction as a therapeutic strategy KRAS-mutant rectal cancer interactions Immunocompetent murine cancer models Molecular mechanisms of methionine dependence Scientific Awards: NIH/NIGMS COBRE (P20) grant for metabolic research Arkansas Bioscience Institute/UAMS funding for cachexia studies Team Science Award from UAMS Cancer Institute KL2 Mentored Research Career Development Scholar Pilot Award from UAMS College of Medicine Advising & Grants: Dr. Miousse has mentored students like Clai Morehead (MD/PhD candidate) and received funding for projects on methionine restriction with immune checkpoint inhibitors in melanoma, radiation therapy synergy with methionine restriction in rectal cancer, and proteomics studies on melanoma metabolism. Labs & Teams: She works from the Biomedical Research Center 1, B421E office and B410 lab. Her team includes Staff Scientist Sarita Garg and has hosted summer students and research technologists.

Katherine Amatoمشاهده پروفایل

دانشیار

• Gut microbiota
• Primate ecology
• Human evolution
• +۳ مورد دیگر

Katherine Amato is an Associate Professor in the Department of Anthropology at Northwestern University's Weinberg College of Arts & Sciences. Her research focuses on the role of gut microbiota in host ecology and evolution, using non-human primates as models to understand microbial contributions to nutrition, energetics, and health. She holds a Ph.D. in Ecology, Evolution & Conservation Biology from the University of Illinois Urbana-Champaign (2013) and completed postdoctoral work at the University of Colorado Boulder. Dr. Amato is affiliated with the Interdisciplinary Biological Sciences Graduate Program and the Northwestern Institute on Complex Systems. Professional roles include President of the Midwest Primate Interest Group, Associate Editor at Microbiome , and Editorial Board member at Folia Primatologica . Her key research areas include microbiome adaptation to environmental stress, host genetics-microbiome interactions, and the evolutionary origins of human fermented food consumption. Education: A.B., Biology (Dartmouth College); Ph.D., Ecology, Evolution & Conservation Biology (UIUC) Affiliations: CIFAR Fellow (Humans & Microbiome Program) Her work bridges biological anthropology and microbial ecology, exploring how microbiomes buffer hosts against nutritional challenges and shape inter-specific metabolic differences. Recent studies investigate global human microbiome variation and its links to local adaptation. She teaches courses such as Primate Behavior and Ecology , Human Microbiome and Health , and Microbiome Analysis . Notable contributions include identifying fermented food consumption in wild primates and its ecological drivers, and highlighting microbiome disparities linked to health inequities. Her lab employs multi-omics approaches to study microbiome dynamics across species and environments.

Raquel Diasمشاهده پروفایل

استادیار

• Bioinformatics
• Genomics
• Machine Learning in Agriculture
• +۴ مورد دیگر

Raquel Dias is an Assistant Professor in the Department of Microbiology & Cell Science at the University of Florida. Her research focuses on integrating computational biology, genomics, and machine learning to address challenges in agriculture, microbial ecology, and human health. Key areas include genomic sequence analysis, protein structure-function relationships, and the application of AI in clinical diagnostics. Education details are not explicitly provided in the text, but her publications suggest advanced training in computational biology, bioinformatics, and microbiology. Her work spans diverse topics such as soil microbiome dynamics in agricultural systems, genetic risk prediction for hearing disorders, and developing novel machine learning models for genotype imputation. Research interests emphasize interdisciplinary approaches, including: Machine learning applications in genomics and proteomics Microbial community analysis in environmental and clinical contexts Development of predictive models for disease progression and genetic associations Her recent publications highlight trends in AI-driven genomic analyses, polygenic risk scoring, and the functional characterization of uncharacterized proteins. Notable projects include the STICI and InteracTor tools for genomic and protein analysis. No scientific awards or grants are explicitly listed in the provided text. She maintains an active lab focused on computational biology and microbial genomics, collaborating with institutions in Brazil and the U.S. on projects related to crop improvement, soil health, and human health informatics.

• Cystic Fibrosis
• Alpha-1 Antitrypsin Deficiency
• Lung Inflammation
• +۳ مورد دیگر

Prof. Noel G McElvaney is Head of the School of Medicine and Professor of Medicine at the Royal College of Surgeons in Ireland (RCSI). He holds a medical degree from University College Dublin (1982). His research focuses on cystic fibrosis (CF), alpha-1 antitrypsin deficiency (AATD), lung inflammation, and protease regulation. He has led translational research initiatives, including early clinical trials of therapies like Lomucin and AAT augmentation. In 2001, he founded the Alpha One Foundation of Ireland and established Europe’s first AATD detection program. Prof. McElvaney has secured extensive funding from organizations like HRB, SFI, and industry partners. His work bridges clinical practice and research, emphasizing gene therapy, lung defense mechanisms, and drug development. He has been awarded the HRB Impact Award (2021-2022) and holds leadership roles in medical councils and societies. His lab collaborations include Beaumont Hospital and global networks like the European Alpha-1 Research Collaboration (EARCO). Research interests include: protease-antiprotease balance in lungs, bronchial epithelium signaling, innate immunity, and CF/AATD therapies. He has supervised multiple research projects and mentored students in areas like CF microbiota and estrogen effects. His recent grants fund studies on COPD microbiome diversity, circadian rhythms in lung disease, and longitudinal biomarker analyses in AATD.