MARCOS FERNANDEZ FONDEVILA

Marcos Fernandez Fondevila is a researcher specializing in Physiology at the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) within the University of Santiago de Compostela. He is affiliated with the GIBIOMED Biomedical Research Group, focusing on liver diseases and metabolic disorders.

• Education: PhD in Medicine from the University of Santiago de Compostela (2021), with a thesis on the role of the L-α-lysophosphatidylinositol/GPR55 system in non-alcoholic steatosis and steatohepatitis.

Research Interests center on:

• Molecular mechanisms of steatotic liver disease (NASH/MASLD)
• Gut microbiota-liver axis interactions
• Role of protein modifications (e.g., NEDDylation, O-GlcNAcylation) in metabolic regulation
• Intestinal barrier function in alcohol-related liver disease
• Signaling pathways in hepatic fibrosis (p63, TLR4, HER2)
• Neutrophil-mediated inflammation in hepatitis

Research Trends from recent publications reveal a focus on alcohol-associated liver disease, metabolic dysregulation, and gut-liver axis dynamics. His work explores NEDDylation in aging, intestinal retroviruses in liver pathology, and microbial metabolites as disease drivers.