جست‌وجوی استاد و پژوهشگر

Andre Frankeمشاهده پروفایل

استاد

• Genetics
• Genomics
• Immunogenetics
• +۷ مورد دیگر

Prof. Dr. Andre Franke is a Full Professor of Molecular Medicine at the Christian-Albrechts-University of Kiel (CAU) and Managing Director of the Institute of Clinical Molecular Biology (IKMB). He leads the Genetics and Bioinformatics group and oversees high-throughput facilities at the Centre for Molecular Biosciences. Franke serves as the speaker for the DFG Research Training Group 1743 and the research unit miTarget. Education: Diploma in Biology (2003), Christian-Albrechts-University of Kiel Dr. rer. nat. in Genetics (2006), Christian-Albrechts-University of Kiel His research integrates high-throughput technologies and bioinformatics to investigate genetic and epigenetic mechanisms of chronic inflammatory diseases. Key interests include: Genome-wide association studies (GWAS) for Crohn's disease and ulcerative colitis Host-microbiome interactions and microbial genomics Immunogenetics of psoriasis and autoimmune disorders SARS-CoV-2 genetic susceptibility and COVID-19 severity factors Recent publications (2022-2024) demonstrate a focus on immunopeptidomics, T-cell receptor dynamics, gut microbiome ecology , and inflammatory disease mechanisms . His work frequently combines multi-omics approaches with large-scale clinical cohorts to identify therapeutic targets. Scientific Awards: Thannhauser Prize (2017) - German Society for Digestive and Metabolic Diseases Schleswig-Holstein Excellence Chair (2017) Ludwig-Demling Research Prize (2012) Janssen Prize (2011) Hensel Prize (2008) Franke leads interdisciplinary teams managing genomic data infrastructure, biobanking, and high-throughput sequencing platforms. His collaborations include international consortia like the IBD Genetics Consortium.

Carol Kumamotoمشاهده پروفایل

استاد

• Candida albicans
• Opportunistic Fungal Pathogenesis
• Host-Pathogen Interactions
• +۵ مورد دیگر

Carol Kumamoto is a Professor at Tufts University School of Medicine in the Department of Molecular Biology and Microbiology. Her research focuses on Candida albicans pathogenesis, host-fungal interactions, and gut microbiome dynamics. Doctor of Philosophy, University of California, 1980 Artium Baccalaureatus, University of California, 1975 Dr. Kumamoto investigates environmental cues triggering C. albicans filamentous growth, virulence mechanisms, and how host colonization impacts disease progression. Her work spans molecular biology, microbial ecology, and translational studies in immunocompromised populations. Recent publications highlight cross-kingdom interactions between Candida and gut bacteria, ethanol tolerance in fungi, and gut-brain axis modulation. Key journals include PLOS Pathogens , Cell Host & Microbe , and Gastroenterology . Elected Fellow, American Academy of Microbiology (2019) Elected Fellow, AAAS (2014) Outstanding Tufts Lecturer (2015-2017) She teaches Intro to Microbiology and has led NIH-funded projects on fungal virulence, probiotics, and enteric disease models. Grants include NIH R01 and U19 awards (2003-2022).

• Gut Microbiota
• Microbiota-Gut-Brain Axis
• Irritable Bowel Syndrome (IBS)
• +۸ مورد دیگر

Premysl Bercik is a Professor in the Department of Medicine at McMaster University's Faculty of Health Sciences. His research focuses on the interaction between gut microbiota and the host's nervous and immune systems, particularly in disorders like irritable bowel syndrome (IBS), celiac disease, and inflammatory bowel disease (IBD). He has led studies on dietary interventions, microbial metabolites (e.g., histamine, phospholipids), and their impact on visceral pain and behavioral changes using humanized and gnotobiotic mouse models. Institution: McMaster University School: Faculty of Health Sciences Department: Department of Medicine Academic Rank: Professor Research Interests: Bercik's work explores the microbiota-gut-brain axis, emphasizing how gut bacteria influence chronic gastrointestinal disorders, mood, and immune responses. Key areas include gluten/wheat effects on IBS, tryptophan metabolism via the aryl hydrocarbon receptor, proteolytic microbiota in Crohn's disease, and stress-induced bacterial translocation. His studies often bridge microbiology, immunology, and neuroscience to uncover mechanisms linking gut health to systemic and psychological conditions. Recent Research Trends: His 2025-2024 publications highlight microbial phospholipids (LPC/LPA) as pain triggers in IBS, TRPC5/LPAR1-3 signaling in visceral hypersensitivity, and microbiota-mediated CGRP regulation. He investigates dietary interventions (low-FODMAP, tryptophan supplementation) and microbial metabolites' role in schizophrenia, Crohn's disease, and post-infectious IBS. His team also examines how rodent diet variability affects experimental reproducibility in microbiome research. Collaborations: Bercik collaborates with institutions like Queen's University and leverages McMaster Experts for scholarly activity. His work spans clinical trials (e.g., gluten-free diet efficacy), mechanistic studies on receptors like PAR2 and AHR, and translational models of stress and dysbiosis.

Michael Wesselsمشاهده پروفایل

استاد

• Infectious Diseases
• Microbiology
• Bacteriology
• +۳ مورد دیگر

Roles and Affiliations Michael Wessels is a Senior Physician in the Division of Infectious Diseases at Boston Children’s Hospital, the John F. Enders Professor of Pediatrics, and a Professor of Medicine (Microbiology) at Harvard Medical School. He has held leadership roles, including Chief of the Division of Infectious Diseases at Boston Children’s Hospital from 2000 to 2018. His clinical and research expertise focuses on streptococcal infections, particularly Group A and B Streptococcus, and their pathogenic mechanisms. Education Bachelor’s degree from Oberlin College M.D. from Duke University School of Medicine (1979) Residencies and fellowships at Beth Israel Deaconess Medical Center and Brigham & Women’s Hospital Research Focus Dr. Wessels’ research investigates molecular interactions between pathogens and hosts, with emphasis on Streptococcus pyogenes (Group A Streptococcus) virulence factors such as streptolysin O, NAD-glycohydrolase, and the CsrRS regulatory system. Key areas include: Host-pathogen signaling and immune evasion mechanisms Role of human antimicrobial peptides in modulating bacterial virulence Pathogen survival strategies in host cells (macrophages, epithelial cells) Neuronal signaling impacts on immune responses during infections Articles Overview Recent work highlights interactions between bacterial toxins and host immune pathways, including NADase’s role in inflammasome inhibition, and the dual effects of bacterial sphingolipids in colitis. Studies also explore regulatory networks like CsrRS and their environmental triggers (e.g., LL-37 peptide). Awards and Memberships Member: American Society for Clinical Investigation, Association of American Physicians, American Pediatric Society Fellow: Infectious Diseases Society of America, American Academy of Microbiology Grants and Teams Collaborations include work with Isaac Chiu on neuronal signaling in infections. His lab has contributed to vaccine development and understanding pathogen survival mechanisms in host cells. Labs/Teams Research conducted in the Division of Infectious Diseases at Boston Children’s Hospital, focusing on streptococcal pathogenesis, toxin biology, and host immune responses.

• Microbiome Research
• Autoimmune Diseases
• Rheumatology
• +۳ مورد دیگر

Renuka Nayak, MD, PhD, is an Associate Professor of Medicine at the University of California, San Francisco (UCSF) School of Medicine . She holds dual appointments in Medicine and Rheumatology following her clinical training . Her work bridges Biology Computer Science Clinical Rheumatology to investigate the gut microbiome in autoimmune conditions. Her research on rheumatoid arthritis integrates Patient specimen analysis Microbiology Next-generation sequencing Gnotobiotic mouse models to understand the microbiome as a "second genome." Recent publications focus on microbiome-driven therapeutic resistance and metabolite-microbiome interactions in autoimmunity. Key grants include NIH K08AR073930 (2018-2023): Gut microbiome in RA treatment NIH F30ES017584 (2010-2012): Gene networks under radiation stress She collaborates with top researchers in microbiome science including Peter Turnbaugh and Katie Pollard, with datasets accessible through ORCID 0000-0002-1123-4668 . Current projects include developing microbial therapeutics for inflammatory arthritis and exploring pharmacomicrobiomics applications.

• Inflammatory Bowel Disease
• Crohn's Disease
• Ulcerative Colitis
• +۴ مورد دیگر

Noortje Festen is an Associate Professor at the University of Groningen, Faculty of Medical Sciences, working within the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI). She has established herself as a prominent researcher in inflammatory bowel disease (IBD) with significant contributions to understanding the genetic and environmental factors influencing gastrointestinal disorders. Her educational background isn't explicitly detailed in the provided text, but her research leadership position suggests advanced medical and scientific training. Dr. Festen's research focuses primarily on inflammatory bowel disease, with specific expertise in Crohn's disease, ulcerative colitis, gut microbiome interactions, and genetic factors influencing disease progression. Her work spans from fundamental genetic research to clinical applications, particularly examining how diet, environment, and genetics interact in IBD pathogenesis. She has been instrumental in large-scale collaborative projects like the 1000IBD project, which provides multi-omics data from 1000 inflammatory bowel disease patients. Analysis of her recent publications (2025) reveals a strong focus on translational research, with studies examining diet-flare relationships in IBD, gene-environment interactions, and applications of genomic analysis in transplantation medicine. Her work demonstrates interdisciplinary approaches combining genetics, microbiome analysis, and clinical outcomes. Dr. Festen has contributed to significant research outputs including 128 publications, with recent work appearing in high-impact journals such as Journal of Crohn's & Colitis, Hepatology Communications, and Journal of Thrombosis and Haemostasis. Her research has garnered citations and captures readers across multiple platforms. She actively supervises graduate students, having served as co-supervisor for PhD research on gut mucosal gene expression in inflammatory bowel disease. Her collaborative network extends across multiple institutions, as evidenced by her involvement in the TransplantLines Investigators consortium and other multi-center studies. Dr. Festen leads research in the 3GI institute, focusing on the intersection of genetics, immunology, and gastrointestinal diseases. Her team contributes to both clinical research and fundamental science, with particular emphasis on personalized medicine approaches for inflammatory bowel disease patients.

Hang Xiaoمشاهده پروفایل

استاد

• Food-based health strategies
• Gut microbiome
• Plant-based diet
• +۳ مورد دیگر

Hang Xiao is a Professor and Graduate Program Director in the Department of Food Science at the University of Massachusetts Amherst . His research focuses on food components' impacts on health, particularly through interactions with gut microbiome, plant-based diets, and bioavailability enhancement via food processing. Key research areas: Food-microbiome interactions, plant-based health strategies, bioavailability modulation, food toxicology Develops nanoemulsion delivery systems for nutraceuticals He has published over 240 peer-reviewed articles and received numerous awards from the Institute of Food Technologies (IFT), American Chemical Society (ACS), and American Society for Nutrition (ASN). Notable recognitions: IFT Fellow (2020), Babcock-Hart Award (2019), ACS Agricultural/Food Chemistry Fellow (2017) His recent work explores microbiota-mediated metabolism of food bioactives, dietary interventions for colitis, and novel nanostructured delivery systems for enhanced bioavailability.

• Gut Microbiota
• Dietary Fiber
• Immune System Regulation
• +۳ مورد دیگر

Dr. Jian Tan is a Research Fellow at the School of Medical Sciences , part of the Faculty of Medicine and Health at the University of Sydney. His work focuses on the intersection of gut microbiota, dietary metabolites, and immune system regulation. Institution: University of Sydney School: School of Medical Sciences Academic Rank: Research Fellow Dr. Tan's research explores how dietary components like fiber, fatty acids, and macronutrients modulate immune homeostasis through microbiota-derived metabolites. Key themes include: Role of short-chain fatty acids (SCFAs) in mucosal immunity Maternal microbiome effects on offspring immune development Dietary interventions for autoimmune and allergic diseases Metabolic programming of immune cells Recent publications highlight his contributions to understanding: Antibiotic-induced gut dysbiosis and inflammation Protective effects of high-fat diets in CNS autoimmunity Maternal microbiota's impact on infant metabolic health SCFA-mediated regulatory B and T cell differentiation Dr. Tan is a member of the Charles Perkins Centre , a multidisciplinary research hub addressing metabolic diseases, and supervises PhD student Camille POTIER on maternal microbiota-offspring immunity connections.

Chu Yaoمشاهده پروفایل

پژوهشگر ارشد

• Gastroenterology
• Dietary Therapy
• Inflammatory Bowel Disease
• +۴ مورد دیگر

Chu Yao is an **Adjunct Senior Research Fellow** at Monash University's Department of Gastroenterology and an Advanced Practising Gastroenterology Dietitian at Eastern Health. She holds a PhD (2017) focused on gut microbial function and gaseous biomarkers in gastrointestinal diseases. Her research emphasizes dietary therapies for ulcerative colitis, pouch-related symptoms, and the role of protein fermentation in gut health. Awarded finalist for the Gastroenterological Society of Australia Young Investigator Award (2016) Presenter at major conferences like ECCO, IOIBD, and GastroDiet Peer reviewer for journals such as *The Lancet Gastroenterology & Hepatology* and grant reviewer for Swiss National Science Foundation Her work contributes to UN Sustainable Development Goals related to health and well-being. Yao leads initiatives like the Consortium for Research into Eating Disorders (CORED) and chairs the GastroDiet 2024 Conference Organising Committee. Teaching includes guest lectures at Monash University and development of online courses like the Low FODMAP Diet for IBS . She currently supervises 2 PhD students and mentors dietitians at various career stages.

• Gut-Brain Axis
• Microbiome Research
• Neuroinflammation
• +۳ مورد دیگر

Stephen Michael Collins is a distinguished Professor in the Department of Medicine at McMaster University , where he has been a faculty member since 1981. He has held leadership roles including Director of the Intestinal Diseases Research Unit (1983-2017), Chief of Gastroenterology (1993-2006), and Associate Dean for Research (2006-2017). He currently serves as Director of the Farncombe Family Digestive Health Research Institute , which he founded. Medical training: University College & Westminster Hospital, London Specialization: Gastroenterology, Neurogastroenterology His research focuses on the gut-brain axis , particularly how intestinal microbiota modulates neuroinflammation and behavior in health and disease. His work bridges gastroenterology , immunology , and neuroscience , with over 300 publications. Recent studies investigate microbial phospholipids in visceral hypersensitivity, dietary interventions for IBS, and stress-microbiota interactions. Scientific honors include: Fellow of the Royal Society of Canada President of the Canadian Association of Gastroenterology His 15 most recent articles (2014-2025) reveal trends in microbiota-gut-brain axis research, with specific emphasis on lysophospholipid signaling , histamine metabolism , visceral pain mechanisms , and stress-induced microbial translocation . Collaborative work with Canadian Institutes of Health Research and Crohn's Colitis Canada highlights clinical translation.

• Nutrition
• Gastrointestinal Function
• Carbohydrate Metabolism
• +۷ مورد دیگر

Jane Muir is Associate Professor (Research) and Head of Translational Nutrition Science in the Department of Gastroenterology, School of Translational Medicine at Monash University. She is a trained dietitian with a PhD in biochemistry and has over two decades of experience in nutrition research, particularly in the role of fermentable carbohydrates in gastrointestinal health. University: Monash University School: School of Translational Medicine Department: Department of Gastroenterology Position: Associate Professor (Research), Head of Translational Nutrition Science Email: Jane.Muir@monash.edu Her research focuses on the physiological effects of fermentable carbohydrates such as FODMAPs and resistant starch. She developed a key assay for measuring resistant starch in food and has led the creation of comprehensive FODMAP food composition tables. These tools have been foundational in advancing dietary therapies for functional gut disorders, particularly irritable bowel syndrome (IBS). Recent publications highlight her work on the low FODMAP diet’s applications in IBS, prediabetes, pediatric care, endometriosis, and pouch diets. Her research also explores ingestible electronic devices for gut monitoring and the role of dietary fiber in hypertension. Her scientific output shows a strong trend toward translational and clinical nutrition, with increasing interdisciplinary collaboration. Carbohydrate Metabolism Gastrointestinal Function FODMAPs Resistant Starch Clinical Dietetics Translational Nutrition Jane Muir has received no explicitly mentioned scientific awards in the provided text. However, her leadership in major research projects and high-impact publications indicates significant recognition in her field. She has served as Primary Chief Investigator on multiple funded studies, including those investigating dietary therapies for endometriosis and diabetic kidney disease. She collaborates extensively with Prof Peter Gibson and other researchers across gastroenterology, nutrition, and medical technology. While specific students are not named, her role as a senior research leader implies mentorship of junior researchers and students. She is actively involved in research labs and teams focused on gut health, food composition analysis, and clinical dietary interventions. Her work contributes to UN Sustainable Development Goals related to health and well-being.

Sara Dannمشاهده پروفایل

دانشیار

• Enteric Pathogens
• Intestinal Inflammation
• Innate Immunity
• +۷ مورد دیگر

Dr. Sara Dann is an Associate Professor in Internal Medicine and Microbiology & Immunology at the University of Texas Medical Branch (UTMB). She directs the Postdoctoral Certificate Program and holds a joint appointment in the Center for Tropical Diseases. Her research focuses on understanding host-microbe interactions, particularly how enteric pathogens like Giardia and Cryptosporidium trigger intestinal inflammation and how innate immune responses regulate this process. She investigates mechanisms linking dendritic cells, Th17 cells, and cytokines (e.g., IL-10 and IL-22) to intestinal tolerance and colitis. Education: B.S., University of California, Riverside (1995) M.S. & Ph.D., University of Texas School of Public Health, Houston (1999–2005) Postdoctoral Training, University of California, San Diego (2008) Research Interests: Dr. Dann’s work spans infectious diseases, immunology, and inflammatory bowel disease. Key areas include: - Pathogenesis of microbial-triggered colitis - Role of microbiota-derived metabolites (e.g., propionate) - Host defenses against protozoan parasites - Age-related susceptibility to Clostridium difficile infection Grants/Projects: She leads the Scientific Communication Advances Research Excellence (SCOARE) project (2022–2025), funded by the University of Texas MD Anderson Cancer Center, aimed at enhancing research communication. Labs/Teams: Affiliated with UTMB’s Center for Tropical Diseases and collaborates on translational projects involving host-directed therapies for infectious diseases.

• Inflammatory Bowel Disease (IBD)
• Gastroenterology
• Stem Cell Biology
• +۵ مورد دیگر

Torunn Bruland is a top-level researcher and leader in gastroenterology and inflammatory bowel disease (IBD) research at the Norwegian University of Science and Technology (NTNU). She holds leadership roles as Co-Leader of CAG-IBD (Precision Medicine in IBD) and Unit Leader for Gastroenterology, Inflammation, and Clinic-Based Research within the Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences. Her research focuses on IBD mechanisms, organoid-based drug testing, epithelial biology, and microbiota interactions. She has authored/co-authored over 50 peer-reviewed publications since 2001, with recent work emphasizing stem cell behavior, chemokine regulation, and biomarker discovery in IBD. Collaborations include international teams studying fungal microbiota in IBD and hypoxia’s role in organoid differentiation. Key contributions include developing protocols for culturing patient-derived colon organoids and identifying NGAL as a potential biomarker for collagenous colitis. Her work bridges basic science and clinical translation, with a focus on precision medicine for IBD. Awards and grants are not explicitly listed, but her leadership roles suggest sustained institutional and collaborative support. Research interests span IBD pathogenesis, epithelial-immune interactions, and therapeutic innovation. She advises graduate students and collaborates with researchers like Drs. Ingunn Bakke, Shreya Gopalakrishnan, and Atle van Beelen Granlund. Her lab’s work is published in journals like Scientific Reports , Frontiers in Immunology , and Inflammatory Bowel Diseases .

Claudio Fiocchiمشاهده پروفایل

استاد

• Inflammatory Bowel Disease (IBD)
• Immune Regulation
• Gut Inflammation Mechanisms
• +۳ مورد دیگر

Claudio Fiocchi is a Professor in the Department of Molecular Medicine and the Department of Inflammation and Immunity at the School of Medicine, Case Western Reserve University. He is also a Member of the Immune Oncology Program at the Case Comprehensive Cancer Center. Research Interests : His work focuses on the pathogenesis of inflammatory bowel disease (IBD), specifically investigating immune mechanisms in gut inflammation, T-cell survival and tolerance, interactions between immune cells and stromal components, and immune-driven angiogenesis. Recent advancements include the development of intestinal epithelial organoid models to study luminal influences on epithelial differentiation. Publications : Over 150 publications, with recent trends emphasizing fibrosis mechanisms in IBD, multi-omics approaches, environmental triggers, and therapeutic innovation. Key areas include MFGE8's role in fibrosis inhibition, single-cell RNA sequencing of Crohn's disease fibroblasts, and anti-IL-6R antibody trials. Grants & Labs : Research supported by NIH/NIDDK grants. Leads a lab studying mucosal immunology, epithelial cell dynamics, and translational IBD therapies. Collaborates with the Lerner Research Institute (Cleveland Clinic) and the Case Comprehensive Cancer Center.

Jim Gonzalez Castellanosمشاهده پروفایل

استادیار

• Immunology
• Gastroenterology
• Microbiome
• +۳ مورد دیگر

Jim Gonzalez Castellanos serves as Assistant Professor of Anesthesiology at Weill Cornell Medical College, Cornell University, and Assistant Attending Anesthesiologist at NewYork-Presbyterian Hospital. His dual expertise spans clinical anesthesiology and translational immunology research, with a focus on gut-immune axis mechanisms in inflammatory diseases. His educational credentials include: M.D., Ph.D. from Weill Cornell Medical College, Cornell University (2020) M.F.A. from University of Arizona (2011) B.A. from Claremont McKenna College (2009) Dr. Castellanos' research investigates innate lymphoid cell dynamics in mucosal immunity, with particular emphasis on microbiome-dysbiosis interactions driving conditions like Crohn's disease and colitis. His work bridges anesthesiology with immunological mechanisms of tissue repair and inflammation, exploring how bacterial strains (notably IgA-coated E. coli) trigger TH17-dependent pathways in autoimmune disorders. This translational approach extends to infection control methodologies including UV-C sterilization systems. Analysis of his 10 publications (2010-2022) reveals consistent focus on gut-immune crosstalk, with landmark studies in Nature Medicine (496 citations) and Science Translational Medicine (249 citations) establishing fundamental mechanisms in inflammatory disease pathogenesis. His work demonstrates progressive specialization from T-cell immunology toward microbiome-mediated inflammatory pathways. Dr. Castellanos currently leads the Howard Hughes Medical Institute-funded project "Molecular Dynamics of Tissue Repair in Burns" (2025-2029) as Principal Investigator, indicating active expansion into burn injury repair mechanisms while maintaining his core focus on inflammation-microbiome interactions. His research program operates at the intersection of anesthesiology, immunology, and gastrointestinal pathophysiology.