جست‌وجوی استاد و پژوهشگر

Hilary Ann Collerمشاهده پروفایل

استاد

• Cellular Quiescence
• Cancer Biology
• Metabolism
• +۴ مورد دیگر

Hilary Ann Coller is a Professor at the University of California, Los Angeles (UCLA), jointly appointed in the Department of Molecular, Cell and Developmental Biology and the Department of Biological Chemistry within the College of Letters and Science. She leads a research laboratory focusing on cellular quiescence, metabolism, and their implications in cancer and disease progression. Her research integrates molecular biology, epigenetics, and systems approaches to study: Transcriptional and epigenetic control of quiescence Metabolic adaptations in tumor microenvironments RNA biology and gene regulation networks Development of biomedical technologies (e.g., biosensors) Recent publications (2022–2025) highlight trends in: Cellular quiescence mechanisms and transcription factor dynamics Cancer epigenetics and metabolic reprogramming Innovative tools for metabolomics and drug monitoring Educational research on remote STEM training programs She directs multiple NIH-funded projects, including R01CA221296 (stromal autophagy in melanoma) and R01GM086465 (microRNA mechanisms). Her lab mentors graduate students and postdocs, and she co-leads UCLA’s Bruins-in-Genomics summer initiative for undergraduate computational biology training.

Jose M Silvaمشاهده پروفایل

استاد

• Cancer Biology
• Cancer Genetics
• Tumorigenesis
• +۵ مورد دیگر

Jose M Silva is a Professor in Pathology and Oncological Sciences at Columbia University Medical School. He holds adjunct faculty status and has prior roles including Assistant Professor at Columbia and postdoctoral training at Cold Spring Harbor Laboratory. His research focuses on cancer genomics, functional networks, and translating discoveries into clinical applications. He has pioneered integrative approaches combining genomics and systems biology to identify critical cancer cell regulators, leading to clinical trials. Education: BSc, Complutense University of Madrid PhD, Autonoma University of Madrid PostDoc & Senior Fellow, Cold Spring Harbor Laboratory Research Interests: His lab investigates breast cancer development and therapeutics, including molecular characterization of tumor networks, novel drug targets (e.g., RSF1, BIN3), and clinical translation of discoveries. Current efforts target triple-negative breast cancers and aging-cancer intersections. Grants & Trials: Initiated NCT02066532 clinical trial; ongoing work includes HDAC6/STAT3 inhibition studies and single-cell atlas projects.

Melissa Carasمشاهده پروفایل

استادیار

• Auditory Neuroscience
• Perceptual Learning
• Neuroplasticity
• +۳ مورد دیگر

Melissa Caras is an Assistant Professor in the Department of Biology at the University of Maryland, with an affiliation in the Department of Hearing and Speech Sciences. She holds a B.S. in Neuroscience and Biology from Brandeis University and a Ph.D. in Neurobiology and Behavior from the University of Washington. Her postdoctoral training at New York University focused on auditory development and perceptual learning. Her research explores neural mechanisms of auditory learning and plasticity, employing techniques like electrophysiology, optogenetics, and telemetry. Research interests include auditory neuroscience, perceptual learning, neuroplasticity, and cognitive neuroscience. Her work emphasizes top-down modulation of sensory processing and the impact of non-sensory factors on auditory learning. Recent studies investigate orbitofrontal-auditory pathways in gerbils and neural correlates of perceptual plasticity in auditory circuits. Current students include Ying, Rose and Marissa, Renee. The CarasLab website (caraslab.org) highlights her lab’s focus on sensory plasticity mechanisms. No scientific awards are explicitly mentioned, but her research has contributed to understanding developmental hearing loss and neural variability in adolescents.

• Genetics
• Bioinformatics
• Immunology
• +۳ مورد دیگر

Overview Francesc Lopez-Giraldez is a Research Scientist in Genetics at the Yale School of Medicine, with affiliations in the Yale Center for Genome Analysis (YCGA) and the Center for Biomedical Data Science. His research focuses on integrating genomics, bioinformatics, and molecular biology to address complex biological and clinical questions in areas such as cancer, neurodevelopmental disorders, and immune-related diseases. Education PhD in Evolutionary Genetics, Autonomous University of Barcelona (2006) MSc in Health and Life Sciences, Pompeu Fabra University (2004) BS in Biology, University of Girona (2000) Research Interests Lopez-Giraldez’s work spans genetics, immunology, and computational biology. Key areas include: Genetic mechanisms underlying congenital heart diseases and neurodevelopmental disorders Bioinformatic analysis of cancer genomics and immune checkpoint resistance Role of mTOR signaling in vascular and neurological pathologies Spatial transcriptomics to study tumor microenvironments and autoimmune diseases Key Contributions Recent publications highlight his interdisciplinary approach, such as: Identifying genetic contributions to congenital heart diseases Elucidating mTOR dysregulation in lissencephaly Exploring immune checkpoint inhibitors’ resistance mechanisms in lung cancer Awards & Recognition Recipient of the National Cancer Institute Research Specialist Award (R50) in 2023, recognizing his innovative contributions to biomedical data science and translational research. Collaborations Lopez-Giraldez collaborates with leading researchers, including Jeffrey Townsend (Yale), Murat Gunel (Neurology), and Kasia Politi (Oncology), to advance team science in precision medicine and genomics. Labs & Teams He contributes to the Yale Center for Genome Analysis (YCGA) and the Yale Cancer Center, focusing on genomic data integration and bioinformatics pipelines for clinical research.

Ulrike Kutayمشاهده پروفایل

استاد

• Nuclear envelope structure and biogenesis
• Nucleo-cytoplasmic transport
• Metazoan ribosome biogenesis
• +۳ مورد دیگر

Ulrike Kutay is a Full Professor of Biochemistry at ETH Zurich, Switzerland, with a research focus on nuclear biology and dynamics. Her work investigates nuclear envelope structure/function, ribosome biogenesis, and nucleo-cytoplasmic transport. Diploma in Biochemistry (Free University Berlin, 1992) PhD in Natural Sciences (Humboldt University Berlin, 1996) Research interests center on nuclear compartmentalization, including mitotic nuclear envelope breakdown and reassembly, ribosome assembly pathways, and the molecular mechanisms governing nuclear transport. Her lab explores how nuclear dysfunction contributes to diseases like ribosomopathies and cancer. Recent publications highlight her work on SUN/KASH proteins in nuclear envelope dynamics, ribosome biogenesis steps, and nuclear pore complex regulation. Collaborations with groups like the Spahn lab in Berlin underscore her interdisciplinary approach. EMBO Member (2010) Leopoldina Member (2012) ERC Advanced Grant (2012) As a mentor, she has supervised PhD students including Chiara and Roja. She actively participates in editorial boards, grant review panels (e.g., ERC, DFG), and institutional leadership roles at ETH Zurich and the Biochemistry Center Heidelberg. The Kutay Group at ETH Zurich combines proteomics, functional analyses, and structural studies to unravel nuclear processes, fostering a collaborative environment with recent achievements in mitotic nuclear disassembly and ribosome maturation research.

Haiyan Huمشاهده پروفایل

استاد

• Computational Biology
• Bioinformatics
• Machine Learning
• +۱۰ مورد دیگر

Haiyan Hu is a Professor at the Department of Computer Science, University of Central Florida (College of Engineering and Computer Science), where she leads the Data Integration and Knowledge Discovery Lab. Her work bridges computational biology, bioinformatics, and machine learning to address challenges in biomedical research, particularly in understanding gene regulation, microRNA, and long non-coding RNA mechanisms linked to diseases like cancer, Alzheimer’s, and Parkinson’s. Education Ph.D. in Computer Science, University of Southern California Research Focus : Dr. Hu’s research applies big data mining, statistical pattern recognition, and deep learning to genomic and epigenetic data analysis. She develops computational methods for knowledge discovery in complex biological systems, with emphasis on disease mechanisms and regulatory networks. Scientific Recognition : NSF CAREER Award, 2012-2019 UCF Research Incentive Awards (2014, 2019) UCF Reach for the Stars Award (2015) Labs and Collaborations : Dr. Hu directs the Data Integration and Knowledge Discovery Lab, fostering interdisciplinary research that integrates computational approaches with biomedical applications.

Armina Kaziمشاهده پروفایل

دانشیار

• Cancer Biology
• Drug Resistance
• Breast Cancer
• +۴ مورد دیگر

Armina Kazi serves as an Associate Professor in the Department of Biology at Loyola University Maryland, Baltimore. Contact details: Office: Dorothy Day 051 Email: aakazi@loyola.edu Phone: 410-617-2319 Dr. Kazi's research program centers on breast cancer drug resistance mechanisms and novel therapeutic development. Her work investigates biomarkers and therapeutic targets in resistant cancer, explores the relationship between drug resistance and cancer stem cells, and evaluates microRNAs as diagnostic predictors for treatment resistance. This multifaceted approach addresses critical challenges in oncology treatment failure. Analysis of her 2012-2015 publications reveals consistent thematic focus on overcoming aromatase inhibitor resistance and triple-negative breast cancer through epigenetic modifiers (particularly histone deacetylase inhibitors like entinostat), HER2 signaling modulation, and cancer stem cell targeting. Her research demonstrates strong translational emphasis on combination therapies and biomarker discovery to improve clinical outcomes in resistant disease.

Nancy Papalopuluمشاهده پروفایل

استاد

• Developmental Neuroscience
• Cell State Transitions
• Gene Expression Dynamics
• +۳ مورد دیگر

Nancy Papalopulu is Professor of Developmental Neuroscience in the Faculty of Life Sciences at the University of Manchester, where she leads research on cell state transitions and gene expression dynamics during development. Currently holding a Wellcome Trust Investigator Award (2022-2027), she has been a prominent figure in developmental neuroscience for over two decades, previously serving as a Wellcome Trust Senior Research Fellow from 2006-2022 and at the Wellcome Trust/Cancer Research UK Gurdon Institute in Cambridge from 2000-2006. Her research focuses on understanding how cells transition from progenitor states to differentiation with precise timing, or enter quiescence from which they may be reactivated. Using single cell quantitative approaches, live imaging, multiple experimental model systems (including Xenopus, zebrafish, and stem cell cultures), and mathematical modeling, her lab investigates the dynamics of gene expression that underlie cell fate decisions. A key contribution has been the hypothesis that the mutually antagonistic interaction between the neural progenitor transcription factor Hes1 and microRNA miR-9 generates pulsatile gene expression at the single cell level, which can transition to stable states in a time-controlled manner. Analysis of her recent publications reveals a strong focus on oscillatory gene expression patterns, neural development mechanisms, and the role of dynamics in cell fate determination. Her work spans developmental neuroscience, cancer biology (particularly glioblastoma), and pancreatic development, demonstrating the broad applicability of her research on gene expression dynamics. Scientific Awards and Recognition: Wellcome Trust Investigator Award (2022-2027) Wellcome Trust Senior Research Fellow (2006-2022) Wellcome Trust Senior Research Fellow (2000-2006) Wellcome Trust Career Development Fellow (1997-2000) Post-doctoral Fellow, Human Frontier Science Program Organization (1991-1996) Professor Papalopulu supervises multiple PhD students and postdoctoral researchers through various funding mechanisms including Wellcome Trust, MRC, and CRUK. Her current projects include 'A quantitative and dynamical approach to understanding cell state transitions' (2022-2027), 'Decoding Pulsing Proteins in the Pancreas' (2018-2022), and participation in the Centre for Biological Timing. Her laboratory team consists of postdocs, PhD students, and technicians working collaboratively on multiple aspects of developmental dynamics. The Papalopulu Lab maintains a strong presence in the field with 88 research outputs and active collaborations across multiple institutions. Her work contributes to UN Sustainable Development Goals related to good health and well-being through advancing fundamental understanding of developmental processes that underlie tissue formation, maintenance, and disease.

Lukas Edward Dowمشاهده پروفایل

استاد

• Cancer Biology
• Genetics
• Molecular Biology
• +۵ مورد دیگر

Lukas Edward Dow is a Professor of Biochemistry and Biophysics at Weill Cornell Medical College (2025-present) and holds a secondary appointment in Medicine. His research spans genetic and non-genetic resistance mechanisms in KRAS-driven cancers, WNT signaling, and CRISPR-based cancer modeling. Ph.D. and B.Sc. from University of Melbourne Focus on CRC, pancreatic, breast, and prostate cancers Research interests include genetic resistance mechanisms , CRISPR applications , WNT pathway dependencies , and tumor microenvironment dynamics . Key publications reveal trends in mutant-specific therapies , epithelial plasticity , and precision genome editing . Current research projects funded by National Cancer Institute and Department of Defense investigate KRAS allelic imbalance, R-Spondin sensitization, and WNT pathway alterations. External collaborations include scientific advisory roles at Mirimus, Inc. and consulting at Revolution Medicines, Inc. His lab develops genetically engineered mouse models and organoid systems for studying cancer progression, with emphasis on metastasis , drug resistance , and epigenetic adaptations . The work has significant implications for improving cancer therapies through context-dependent targeting .

• Cell Adhesion
• Epithelial Cell Biology
• Desmosomes
• +۷ مورد دیگر

Kathleen J. Green, PhD, is the Joseph L. Mayberry, Sr. Professor of Pathology and Toxicology and Professor of Dermatology at Northwestern University's Feinberg School of Medicine . She serves as Associate Director for Basic Sciences at the Robert H. Lurie Comprehensive Cancer Center and is affiliated with the Skin Biology and Diseases Resource-Based Center and Center for Genetic Medicine . Education: PhD in Cell and Developmental Biology (Washington University, 1982), Postdoctoral Training in Cell Biology (Northwestern, 1987) Green's research focuses on desmosomes —cell-cell adhesion structures—and their roles in epithelial tissue morphogenesis, cancer progression, and genetic skin diseases . Her work bridges basic science with translational applications , particularly for inflammatory skin diseases, melanoma, and heart disease . Recent publications highlight her lab's exploration of desmosome-mediated signaling pathways in skin stratification, melanoma growth, and inflammatory responses. Key themes include mechanotransduction, polarity regulation, and endosomal trafficking of adhesion proteins. Scientific Awards: Elected, German National Academy of Sciences (2016) Humboldt Research Award (2015) Tripartite Legacy Faculty Prize (2019) Feinberg Distinguished Woman in Medicine and Science (2011) Kligman Frost Leadership Award (2015) Green has mentored over 30 years, with former trainees now faculty at institutions like Emory, Yale, and Penn State. Her lab fosters collaborative, interdisciplinary research using human disease models, proteomics, and biophysical approaches to study epithelial mechanics.

C. Brooks Mobleyمشاهده پروفایل

استادیار بالینی

• Skeletal Muscle Physiology
• Molecular Mechanisms of Exercise Training
• Sports Supplements
• +۳ مورد دیگر

Dr. C. Brooks Mobley is an Assistant Clinical Professor at the School of Kinesiology, Auburn University. He directs the TigerFit Health & Fitness Laboratory and serves as Associate Director of the Nutrabolt Applied and Molecular Physiology Lab. With a Ph.D. in Kinesiology from Auburn University and postdoctoral training at the University of Kentucky, he specializes in skeletal muscle physiology and sports nutrition research. B.S. in Animal & Dairy Sciences (Auburn University) M.Ed. in Exercise Physiology (Auburn University) Ph.D. in Kinesiology (Auburn University) Postdoctoral Fellowship at University of Kentucky's College of Medicine His research explores molecular mechanisms of muscle plasticity, focusing on: Cellular adaptations to exercise training Ergogenic effects of sports supplements Muscle atrophy prevention strategies Mechanisms of skeletal muscle hypertrophy Angiogenesis in recovery scenarios Muscle-bone interaction dynamics Recent publications demonstrate expertise in: Mitochondrial adaptations to resistance training Epigenetic regulation of muscle growth Microbiome-exercise interactions Proteomic responses to disuse atrophy Firefighting occupational physiology Supplement efficacy studies Laboratory Leadership: TigerFit Health & Fitness Laboratory Nutrabolt Applied and Molecular Physiology Lab

• Pulmonary Fibrosis
• Lung Aging
• Single-Cell Profiling
• +۳ مورد دیگر

Taylor Adams is a Researcher at the Yale School of Medicine's Internal Medicine Department, affiliated with the Kaminski Lab. Their work focuses on pulmonary fibrosis mechanisms, lung aging, and single-cell profiling, with a particular emphasis on epigenetic and immunological pathways. Adams collaborates closely with senior investigators like Naftali Kaminski, contributing to studies on fibrogenesis, drug development, and cellular dynamics in lung diseases. Research interests include understanding how epigenetic changes, microRNA regulation, and immune-cell interactions drive fibrotic processes. Recent work explores novel biomarkers for disease progression and non-invasive diagnostic methods. Adams' publications highlight advancements in spatial transcriptomics, somatic mutation analysis in aging lungs, and the role of GPR87 and CD103+ dendritic cells in fibrosis. Key contributions include identifying aberrant basaloid cells in IPF and developing computational tools like SDePER for deconvolving spatial transcriptomic data. Their lab's interdisciplinary approach integrates genomics, bioinformatics, and experimental models to translate findings into therapeutic strategies.

Syed Hashshamمشاهده پروفایل

استاد

• Environmental Biotechnology
• Microbial Ecology
• Bioremediation
• +۴ مورد دیگر

Syed Hashsham is a Professor in the Department of Civil and Environmental Engineering at Michigan State University (MSU), with an adjunct appointment in the Center for Microbial Ecology and Plant, Soil, and Microbial Sciences. His research focuses on microbial community dynamics, field-deployable genetic testing tools, and environmental biotechnology processes. He leads the NIEHS Superfund Research Center’s Project 4 on dioxin remediation and has pioneered innovations like the Gene-Z handheld genetic analyzer and antimicrobial resistance gene screening chips. Education: Ph.D. in Environmental Engineering (University of Illinois, 1996), M.S. in Environmental Science (IIT Bombay, 1986), B.S. in Civil Engineering (Aligarh Muslim University, 1984). Research interests include microbial community stability, bioremediation of chlorinated solvents, and development of low-cost diagnostic tools. His work bridges environmental engineering and microbiology, with applications in water safety, soil remediation, and public health. Over 150 peer-reviewed publications and numerous grants from NIH, EPA, and other agencies highlight his impact. Notable awards include the MSU Distinguished Faculty Award (2011) and the Withrow Distinguished Scholar Award (2007). He teaches courses like Biological Processes in Environmental Engineering (ENE804) and advises on capstone projects. His lab has produced pioneering technologies for real-time microbial detection and environmental monitoring. Grants and collaborations span multi-million-dollar projects with the NIEHS, USDA, and U.S. Army. His team includes postdocs, PhD students, and visiting scholars working on topics like gut microbiome-host interactions and ARG dissemination via biofilms.

• Plant-Pathogen Interactions
• Postharvest Physiology
• Plant Disease Management
• +۴ مورد دیگر

Professor Amanda Able is a Professor in Plant Science at the University of Adelaide, affiliated with the School of Agriculture, Food and Wine within the Faculty of Sciences, Engineering and Technology. She leads research on plant-pathogen interactions, postharvest physiology, and climate stress resilience in crops. With over $9M in competitive grants since 2001, her work focuses on durum wheat stress responses, miRNA regulation, and transgenerational epigenetic effects. She has supervised 18 PhD and 1 MSc graduates since 2002. Awards include the 2006 Tall Poppy of the Year and 2015 USQ Research Alumnus of the Year. Teaching contributions include Deputy Dean (Learning & Teaching) roles (2019–2022), ASPS Teaching Award (2009), and leadership in national education initiatives like the Agriculture Learning and Teaching Academic Standards project. Her Get into Genes program for secondary students won awards for promoting plant science education. Research spans plant disease mechanisms, capsicum ripening, and inquiry-based learning scaffolding. Her 15 most recent articles (2020–2025) emphasize transgenerational stress memory in crops, microRNA networks, and career readiness in science graduates. Collaborations include the Molecular Plant Breeding CRC and ACDA Learning and Teaching Academy. Labs focus on integrative omics approaches to stress biology and agricultural innovation.

James R. Greenمشاهده پروفایل

استاد

• Machine Learning
• Biomedical Informatics
• Computational Biology
• +۹ مورد دیگر

James R. Green is a Professor in the Department of Systems and Computer Engineering at Carleton University , where he has been a faculty member since 2005. He holds a PhD from Queen's University and is a licensed Professional Engineer (P.Eng.) and Senior Member of IEEE. His work integrates machine learning, biomedical informatics, and high-performance computing. His educational background includes: B.A.Sc. in Systems Design Engineering, University of Waterloo (1998) M.Sc.(Eng.), Queen's University (2000) PhD, Queen's University (2005) Dr. Green's research focuses on machine learning challenges in biomedical informatics , particularly class imbalance and rare event prediction. Key areas include protein structure, function, and interaction prediction; microRNA detection in unique species; non-contact neonatal monitoring; and accelerating scientific computing via parallel architectures like the Cell BE processor. His lab has developed several widely used bioinformatics tools such as PIPE, ProtDCal, and PCI-SUMO. His recent publications reflect a strong trend in computational biology and machine learning , with applications in proteomics, genomics, and medical diagnostics. He has published over 100 peer-reviewed papers and secured funding from NSERC, CIHR, CFI, ORF, OCE, MITACS, and IBM. Scientific and teaching recognitions include: Three teaching awards NSERC Best Project Award (twice: 2006-2007 and 2007-2008) Multiple student projects resulting in conference papers (e.g., CMBEC) He has supervised numerous undergraduate capstone projects in areas such as assistive technologies, robotic systems, and bioinformatics. His teaching portfolio includes courses in Pattern Classification, Machine Learning, Computer Architecture, and Biomedical Engineering. He leads an active research group that bridges computer engineering and life sciences, fostering interdisciplinary collaboration. Lab and research team initiatives include: Development of open-access web servers for protein analysis Collaborations with biologists and clinicians Integration of hardware and software for medical applications