جست‌وجوی استاد و پژوهشگر

Alice Dentonمشاهده پروفایل

مدرس

• Immunology
• Inflammation
• Vaccinology
• +۳ مورد دیگر

Dr Alice Denton is a Lecturer in the Centre for Inflammatory Disease at Imperial College London, where she has worked since January 2020. Her research focuses on understanding how fibroblasts influence immune responses during vaccination and aging. She leads a small lab team and has secured significant funding, including an MRC Career Development Award and a Dunhill Medical Trust Seed Award. Education: PhD, University of Melbourne (2006-2010) Postdoc, University of Cambridge (2010-2015) BBSRC FL Fellowship, Babraham Institute (2016-2019) Alice's research explores the interplay between fibroblasts and immune cells in lymph nodes, particularly how inflammation and aging affect fibroblast function. Her work aims to improve vaccine efficacy through better understanding of stromal-immune crosstalk. Key themes include germinal center immunology , lymph node stromal cells , aging immunity , and inflammatory microenvironment . Her recent publications emphasize fibroblast-immune interactions in tertiary lymphoid structures, podoplanin signaling , and TLR4 targeting for vaccine enhancement. She also investigates spatial organization of immune cells during aging and the role of lymphoid stromal cells in supporting macrophages and germinal centers. Scientific Awards: MRC Career Development Award Dunhill Medical Trust Seed Award Alice collaborates with colleagues at Imperial College London and manages multiple responsibilities including teaching, supervision, and lab work. Outside academia, she enjoys baking (especially sourdough bread), creating cat-themed art, and distilling experimental flavors like pea-flavored gin.

Asolina Braunمشاهده پروفایل

پژوهشگر ارشد

• Skin Immunology
• Autoimmunity
• Psoriasis
• +۷ مورد دیگر

Dr. Asolina Braun is a Senior Research Fellow at the Department of Biochemistry & Molecular Biology, Monash University. She actively supervises PhD students and contributes to research in Skin Immunology Psoriasis Pathogenesis Immunopeptidomics Tissue-Resident Memory T Cells . Education : Biology, Hannover Medical School Doctoral Degree in Immunology (Hannover Medical School, Germany, 2011–2014) Postdoctoral Fellowship with Francis Carbone and Thomas Gebhardt (Germany, 2014–2018) Research Focus : Her work explores HLA-Cw6-dependent antigen presentation and TRM cell survival factors in psoriasis, aiming to develop tolerization strategies for autoinflammatory skin diseases. She also pioneered tactile science communication methods for psoriasis outreach. Key Projects : Leading Psoriasis Antigen Triggers (2023–2025) Investigating Influenza Immune Cross-Protection (2024–2027) Validating HLA-Cw6 Antigen Presentation (2020–2022) Awards & Roles : DFG Fellowship Treasurer, Australian and New Zealand Society for Immunology (2018–2022) Executive Committee Member Collaborations span institutions in Australia, Germany, and Denmark, with expertise in flow cytometry , mass spectrometry , and MHC-peptide interactions .

Bill Faquinمشاهده پروفایل

استاد

• Cytopathology
• Head and Neck Pathology
• Thyroid Pathology
• +۵ مورد دیگر

Bill Faquin, MD, PhD is a Professor of Pathology at Harvard Medical School and serves as a Pathologist at Massachusetts General Hospital with subspecialty expertise in Head and Neck Pathology & Cytopathology. He is a key member of the Head & Neck and Endocrine Pathology Division at Massachusetts General Hospital, which handles over 10,000 surgical cases annually and accounts for more than 10% of the MGH Pathology Service case volume. Dr. Faquin is also affiliated with the Center for Head and Neck Cancers at the Massachusetts General Hospital Cancer Center. Dr. Faquin completed his medical education at Harvard Medical School, followed by residency and fellowship training at Brigham and Women's Hospital. He is board certified in Cytopathology and Anatomic Pathology by the American Board of Pathology. His clinical practice focuses on cytopathology (particularly fine-needle aspiration cytology) and head and neck pathology, with special expertise in thyroid and salivary gland neoplasms. Dr. Faquin's research combines expertise in cytopathology and head and neck pathology to investigate key issues in the carcinogenesis of head and neck and thyroid neoplasia. His translational research focuses on the detection, diagnosis, and prognostication of cancers involving the thyroid and salivary glands, squamous cell carcinomas of the oropharynx, and tumors of the jaws and oral cavity. Recent publications demonstrate his leadership in genomic analysis of thyroid carcinoma, molecular diagnostics, and consensus guidelines for mutational testing in thyroid cancer. His work shows a consistent trajectory toward integrating molecular pathology with traditional diagnostic approaches to improve cancer classification and treatment. Among his notable achievements, Dr. Faquin serves as Editor-in-Chief of Cancer Cytopathology, the premier cytology journal, and is the primary author of the Milan System for Reporting of Salivary Gland Cytopathology, which has become a standard reference in the field. These contributions represent significant recognition of his expertise and leadership in cytopathology. As an educator, Dr. Faquin participates in the training of pathology residents and fellows at Harvard Medical School and Massachusetts General Hospital. He is involved in the Head & Neck and Endocrine Fellowship program, which prepares pathologists for academic and clinical leadership roles. His mentorship has contributed to the development of pathologists who have gone on to faculty positions at leading institutions worldwide including the University of Chicago, Mayo Clinic, UCLA, and Harvard Medical School. Dr. Faquin collaborates extensively with the Head & Neck and Endocrine Pathology Division, which includes weekly Head & Neck Pathology Staff Conferences, Head & Neck Tumor Boards, and participation in Endocrine Oncology Conferences. His work bridges clinical practice, research, and education in head and neck pathology, contributing significantly to advances in diagnostic approaches and cancer management.

Miglena K. Komfortiمشاهده پروفایل

پزشک-پژوهشگر

• Breast Pathology
• Gynecologic Pathology
• Diagnostic Pathology
• +۳ مورد دیگر

Miglena K. Komforti, D.O. is a Physician Scientist in the Department of Laboratory Medicine and Pathology at the Mayo Clinic in Jacksonville, Florida. With expertise in breast pathology , gynecologic pathology , and diagnostic precision , she bridges clinical practice and research. Education: Medical degree (Nova Southeastern University), Fellowship (Montefiore Medical Center, Duke University) Professional Memberships: Florida Society of Pathologists, United States and Canadian Academy of Pathology Research Interests focus on breast cancer diagnostics, HER2 testing, and rare pathologies. Her work addresses challenges in surgical pathology, including acinar/tubule formation in carcinomas and metastatic differentiation. She contributes to immunohistochemistry standardization and multimodal imaging correlation . Scientific Awards : Above and Beyond Teamwork Award (2024) Above and Beyond Recognition Program (2024) Employee Recognition Program (2023) Mentorship includes guiding a Phlebotomy student toward anatomic pathology and contributing to educational case studies (e.g., Ductal Carcinoma In Situ). Her publications span breast tumor biology , endometrial cancer , and rare clinical-pathological phenomena .

• Head and Neck Oncology
• Cancer Surgery
• Microvascular Reconstruction
• +۱۲ مورد دیگر

Baran D. Sumer, M.D., is a Professor and Chief of the Division of Head and Neck Oncology in the Department of Otolaryngology – Head and Neck Surgery at UT Southwestern Medical Center, where he has served since 2007. He is also Director of the Head and Neck Oncology Disease Oriented Team at the Simmons Comprehensive Cancer Center and holds the T.C. Lupton Family Professorship in Patient Care. His clinical work spans UT Southwestern Medical Center, Parkland Health & Hospital System, Children’s Medical Center of Dallas, and the North Texas VA Medical Center. Dr. Sumer earned his medical degree from Case Western Reserve University and completed an internship in general surgery, residency in otolaryngology, and fellowship in head and neck oncologic surgery at Washington University in St. Louis School of Medicine, with a focus on transoral laser surgery and microvascular reconstruction. His research focuses on advancing diagnostic and therapeutic technologies for head and neck cancer, including fluorescent imaging, biosensing, photodynamic therapy, and nano-immune-engineering. He is particularly known for developing pH-sensitive nanoparticles for tumor imaging and immunotherapy. His recent publications reveal a strong trend in immunotherapy, tumor microenvironment modulation, fluorescence-guided surgery, and nanoparticle-based drug delivery, often in collaboration with Dr. Jinming Gao. Among his recognitions are being named a top otolaryngologist by D Magazine and receiving the Texas Instruments Corporate Award for Research, the Triological Society Francis Lederer Award, the FUSION Grant for Nanotechnology Research, and the SEBM Best Paper Award. Dr. Sumer is principal investigator on multiple NIH R01 and CPRIT-funded research projects and co-PI on the UT Southwestern Immuno-Oncology Translational Network (IOTN) i3 Center under the Cancer Moonshot. He co-founded OncoNano Medicine Inc. and leads a lab focused on nano-immune-engineering for cancer immunotherapy. He serves as an editor for Annals of Surgical Oncology and reviewer for journals including Nature Biomedical Engineering and Laryngoscope . His lab, located at https://www.utsouthwestern.edu/labs/sumer/ , drives translational research from bench to bedside, with technologies like pegsitacianine in Phase 2 clinical trials and PC7A nanovaccines advancing toward human studies.

Farhat Dinمشاهده پروفایل

پژوهشگر ارشد

• Colorectal Cancer
• mTOR Signaling
• Chemoprevention
• +۳ مورد دیگر

Farhat Din is a Principal Investigator and Honorary Consultant Colorectal Surgeon at the Institute of Genetics and Cancer, University of Edinburgh. Her research focuses on metabolism and energy signaling in colorectal cancer, targeting the mTOR pathway to develop chemopreventive agents like aspirin. Doctor of Medicine (University of Edinburgh, 2007) Bachelor of Medicine and Surgery (University of Manchester, 1996) Bachelor of Science (University of St Andrews, 1993) Her research explores: mTOR signaling in cancer cell survival and metabolism Molecular mechanisms of aspirin's anti-tumor effects Epigenetic regulation and genetic risk factors in colorectal cancer Role of colonic tuft cells and metastasis Recent studies investigate methylation QTLs, early-onset trends in Scotland, and R1 margin impacts in stage III colon cancer. Her work emphasizes pathway-targeted therapies and translational research. Cancer Research UK Clinician Scientist fellowship Projects funded by CRUK, Bowel Cancer UK, and Royal College of Surgeons She leads the Metabolism & Energy Signalling in Colorectal Cancer group and collaborates with researchers like Malcolm Dunlop and Susan Farrington. Her clinical practice integrates with her translational research program.

Neha Goelمشاهده پروفایل

پزشک-پژوهشگر

• Breast Cancer Research
• Health Disparities
• Surgical Oncology
• +۳ مورد دیگر

Dr. Neha Goel is a physician-scientist at Memorial Sloan Kettering Cancer Center, where she serves as Chief of Disparities in the Department of Surgery and holds the Jeanne A. Petrek Junior Faculty Chair. She specializes in breast cancer surgery, including oncoplastic and nipple-sparing procedures, while leading research on neighborhood-level social determinants of health and their biological impact on cancer outcomes. Education: BS from Northwestern University, MD from University of Illinois, and MPH from Harvard T.H. Chan School of Public Health Her research, funded by the National Institutes of Health, investigates how socioeconomic environments ('ZIP code') interact with genomic factors ('Genomic code') to influence breast cancer biology. This work addresses disparities in triple-negative breast cancer incidence and outcomes among underserved populations. Dr. Goel’s publications highlight connections between neighborhood disadvantage, tumor aggressiveness, and survival rates. Her clinical practice at Evelyn H. Lauder Breast Center and Josie Robertson Surgery Center emphasizes patient-centered care, as reflected in her high patient satisfaction scores and recognition in the Gold Humanism Honor Society. Scientific Awards: NIH Cancer Moonshot R37 Funding (2024) Breast Cancer Research Foundation Researcher (2023) Association of Women Surgeons '40 under 40' (2022) ASCO Career Development Award (2021) Marlins Honorary 'Bat Girl' (2021) Arnold P. Gold Humanism in Medicine Award (2010) The Goel lab’s work aims to develop interventions that address environmental drivers of cancer disparities. Her clinical expertise includes lumpectomy, sentinel lymph node biopsy, and axillary dissection procedures.

Deni S. Galileoمشاهده پروفایل

استاد

• Cell Migration
• Neurobiology
• Developmental Biology
• +۳ مورد دیگر

Deni S. Galileo is a Professor in the Department of Biological Sciences at the University of Delaware. His research focuses on cell migration mechanisms in the developing brain and malignant gliomas, utilizing chick embryo models and retroviral gene transfer technologies. His work explores how integrins, extracellular matrix molecules, and adhesion proteins like L1CAM regulate normal and abnormal cell migration. Key projects include developing novel models for studying glioma invasiveness and breast cancer brain metastases, and investigating the role of QSOX1 and PMCA4 in tumor progression. Education: B.A., New College of Florida Ph.D., University of Florida College of Medicine and Whitney Laboratory Postdoctoral Research, Washington University School of Medicine (St. Louis) Research interests span developmental neurobiology, tumor biology, and gene therapy. Current projects include: Control of glioma invasiveness via L1CAM Integrins' roles in neuronal migration and survival Ex vivo analysis of glioblastoma behavior using chick embryos His lab has pioneered the use of replication-competent retroviral vectors and in ovo electroporation for widespread protein misexpression in developing brains. Collaborations with Dr. John Koh (Chemistry and Biochemistry) explore axon outgrowth on gene-patterned cell monolayers. Lab Resources: Office 232 Wolf Hall, Lab 248 Wolf Hall Teaching: Courses include Cell Biology (BISC 305), Developmental Neurobiology (BISC 439/639), and Special Topics in Modern Biological Microscopy (BISC 400). Notable contributions include establishing chick embryo models for studying glioma and breast cancer metastasis to the brain, and discovering roles for integrin α6β1 and α8β1 in cell migration and survival.

• Cell Biology
• Immunology
• Biophysics
• +۳ مورد دیگر

Pablo J. Sáez is a researcher at the University of Hamburg's Medical School, affiliated with the Department of Cell Biology and Immunology. His work focuses on cellular mechanisms of migration, signaling, and structural dynamics in immune and kidney-related cells. He explores processes like dendritic cell migration, podocyte dysfunction in nephropathy, and the role of calcium channels in cellular behavior. His research integrates biophysical and immunological approaches to understand how cell shape, cytoskeletal dynamics, and microenvironment interactions regulate immune responses and disease progression. Notable contributions include studies on membrane blebbing, SPARC-driven tumor progression, and the development of imaging tools for cellular analysis. Key areas of investigation include: cell shape sensing, actomyosin regulation, and the role of septins in immune cell motility. His articles highlight interdisciplinary methods, combining live-cell imaging, molecular biology, and computational modeling to dissect cellular decision-making processes during migration and disease. Scientific achievements include foundational work on exopher-formation in kidney disease and guidelines for functional assays in dendritic cells. His research bridges basic science and clinical applications, aiming to uncover therapeutic targets in immune and renal disorders.

Alain Algaziمشاهده پروفایل

استاد بالینی

• Head and Neck Cancer Treatment
• Immunotherapy
• Clinical Trials
• +۴ مورد دیگر

Dr. Alain Algazi is a Clinical Professor of Medicine at the University of California, San Francisco (UCSF), specializing in medical oncology for head and neck cancers, thyroid cancers, and salivary gland cancers. He leads UCSF's medical therapy program for head and neck cancers and chairs the head and neck cancer research committee. His research focuses on clinical trials evaluating novel immunotherapies and strategies to improve long-term remission in incurable cancers. Dr. Algazi earned his medical degree from the David Geffen School of Medicine at UCLA, completed internal medicine residency at Ronald Reagan UCLA Medical Center, and a hematology-oncology fellowship at UCSF. He is a member of the American Society of Clinical Oncology, Society for Immunotherapy of Cancer, and American Association for Cancer Research. His research encompasses immunotherapy mechanisms, including PD-1/PD-L1 inhibitors, combination therapies, and biomarker studies. Notable contributions include trials investigating durvalumab, tremelimumab, and pembrolizumab in head and neck cancers, as well as studies on tumor immune profiling and regional lymph node dynamics. Dr. Algazi has authored over 150 peer-reviewed publications, focusing on clinical trials, immunotherapy advancements, and molecular mechanisms in oncology. He has led national studies to improve access to experimental therapies and optimize treatment efficacy.

• CRISPR Technology
• Immunotherapy
• Cancer Research
• +۳ مورد دیگر

Xiao Zhou is a Research Fellow at the Yale School of Medicine, where he focuses on advancing CRISPR-based technologies, immunotherapy, and cancer research. He holds a PhD from Boston University (2022) and contributes to interdisciplinary studies at the intersection of genetics, immunology, and virology. His work emphasizes multiplexed gene editing in immune cells, tumor immunology, and vaccine development against pathogens like SARS-CoV-2. Research Interests: Dr. Zhou’s research explores CRISPR applications in cellular engineering, immunotherapy strategies for cancer resistance, and the design of variant-specific vaccines. His studies often involve in vivo CRISPR screens to uncover therapeutic targets in CD8 T cells and regulatory T cell dynamics. Publications: His work spans CRISPR-mediated genome editing, CAR-T cell enhancements, and heterotypic vaccine responses. Recent studies highlight breakthroughs in Cas12a knock-in mice models and mechanisms of tumor immunity. Professional Background: As a Research Fellow, Zhou collaborates with teams advancing translational medicine and viral immunology. His contributions bridge basic science and clinical applications, with a focus on precision interventions in oncology and infectious diseases.

Shariat Shahrokhمشاهده پروفایل

استاد

• Urologic Oncology
• Molecular Mechanisms
• Molecular Markers
• +۵ مورد دیگر

Professor Shahrokh Shariat is the Chair of Urology at the Medical University of Vienna and holds adjunct professorships at Weill Cornell Medical Center (USA), UT Southwestern Medical Center (USA), Charles University (CZ), and Sechenov University (RU). His research focuses on urologic oncology, molecular markers in prostate and bladder cancers, and translational research. He leads international collaborations such as the Bladder Cancer Research Consortium and has pioneered studies on biomarker-driven treatment strategies. With an H-index of 113 (Scopus) and over 15,700 publications, he holds 4 patents and has received prestigious awards including the Matula Award (2014) and multiple honorary doctorates. He serves as Editor-in-Chief of Current Opinion in Urology and is on editorial boards of 26 journals. His work includes clinical trials, outcomes research, and molecular genomics of urothelial carcinoma. Key Positions: Chair of Urology (Vienna), Adjunct Professors at 5+ institutions Research Themes: Molecular oncology, biomarker discovery, personalized therapy He chairs global initiatives like the Upper Tract Urothelial Carcinoma Collaboration and is actively involved in charity work focusing on refugee healthcare.

• Physiology
• Cancer biology
• pH regulation
• +۵ مورد دیگر

Pawel Swietach is Professor of Physiology at the University of Oxford, Head of the Proton Transport Group (DPAG), and Handa Tutorial Fellow at Corpus Christi College. His work bridges cardiac physiology , cancer pH biology , and blood oxygen transport , with a focus on acid-base regulation and its therapeutic implications. PhD in Physiology (Oxford, 2004) First Class BA in Physiological Sciences (Oxford, 2001) His research uncovers how pH gradients govern cell function in heart and cancer, including: Proton-calcium crosstalk in cardiomyocytes Metabolic adaptation to acidosis in tumors Biochemical control of oxygen release in stored blood His 15 most recent publications (2020-2025) span Nature Reviews Cancer , Nature Cardiovascular Research , and Cell Reports , focusing on acid-driven oncogenesis, histone modifications from propionate metabolism, and novel methods for imaging oxygen transport. Key findings include tumor-stroma acid exchange via gap junctions and nuclear pH's role in cardiac gene expression. Honors include: ERC Consolidator Grant (2017) Royal Society University Research Fellowship (2008-2016) CRUK-U.S. Fulbright Scholar (2018) Academia Europaea membership (2024) He leads cross-disciplinary projects funded by British Heart Foundation, ERC, MRC, and industry partners, translating pH biology into clinical tools like FlowScore for blood storage quality assessment.

Lucie Pedutoمشاهده پروفایل

پژوهشگر

• Cancer biology
• Immunology
• Stromal microenvironment
• +۱۱ مورد دیگر

Lucie Peduto is a Principal Investigator and Structure Manager at the Institut Pasteur in Paris, where she leads a research team investigating the role of stromal and perivascular cells in immunity, inflammation, regeneration, and cancer. Her work focuses on understanding how the stromal microenvironment regulates intestinal homeostasis, tumor progression, and immune responses. Her research interests include: Cancer biology and tumor microenvironment Intestinal immunity and barrier function Mesenchymal and perivascular stromal cells Inflammation and fibrosis Regenerative mechanisms and tissue repair Immune cell-stromal cell crosstalk The recent publications highlight a strong focus on stromal regulation in immunity and cancer, with particular emphasis on PDGFRα+ mesenchymal cells, intestinal barrier integrity, and macrophage interactions. Her work integrates genetic models, organoid systems, and immunological assays to dissect molecular and cellular mechanisms in vivo. Scientific awards and recognitions: ERC Proof of Concept Grant 2023 Dr. Peduto supervises several postdoctoral fellows and PhD students, indicating an active mentoring and training role. She leads multiple funded projects, including ERC-CoG-PERIF on perivascular cells in inflammation and regeneration. Her research is supported by major initiatives at the Institut Pasteur, including the Cancer Initiative and stem cell programs. She collaborates with other leading immunologists and cell biologists at the institute and internationally.

Caius Raduمشاهده پروفایل

استاد

• Cancer metabolism
• Nucleotide metabolism
• Molecular imaging
• +۴ مورد دیگر

Caius Radu, M.D., is a full Professor in the Departments of Molecular and Medical Pharmacology and Surgery at the University of California, Los Angeles (UCLA). He also serves as Vice-Chairman of the Department of Molecular and Medical Pharmacology and as Co-Director of the Cancer Molecular Imaging, Nanotechnology, and Theranostics Research Program (CMINT) within the Jonsson Comprehensive Cancer Center. Education: M.D., University of Medicine, Craiova, Romania Postdoctoral training in immunology and cancer biology, University of Texas Southwestern Medical Center (Dallas) Postdoctoral training at UCLA under the mentorship of Dr. Owen Witte Research Interests: Dr. Radu's laboratory investigates the intersection of metabolic signaling , nucleotide metabolism , and immune networks in cancer, with a translational focus on molecular imaging and theranostic applications. Key efforts include elucidating novel mechanisms regulating nucleotide metabolism in pancreatic and prostate cancers, identifying actionable co-dependencies, and developing non-invasive imaging probes that predict therapeutic response. The group integrates rigorous pre-clinical mouse models with cutting-edge PET imaging to accelerate bench-to-bedside translation. Current projects revolve around STING pathway activation , PSMA-targeted radioligand therapy , CD73 adenosine blockade , mutant KRAS inhibition , and mRNA cancer vaccines . These multi-pronged strategies aim to overcome tumor immune evasion, enhance cytotoxic therapies, and personalize treatment selection. Recent Publication Trends: From 2020-2025, the Radu group has published extensively on synergistic combination therapies that pair immune checkpoint modulation with targeted metabolic inhibition. A dominant theme is leveraging nucleoside analog PET tracers (e.g., 18F-FAC, 18F-CFA) to visualize immune activation and metabolic stress in real time. Parallel studies dissect resistance mechanisms to PSMA-targeted alpha therapy and explore STING agonism as a strategy to sensitize otherwise refractory pancreatic and prostate tumors. Scientific Awards & Honors: While the provided text does not enumerate specific awards, Dr. Radu’s leadership roles at UCLA and the Jonsson Comprehensive Cancer Center, along with continuous high-impact publications, attest to sustained recognition in cancer research. Advising & Team: Dr. Radu mentors an active bench-to-bedside team comprising: Graduate Students: Amanda Creech, Hailey Lee Postdoctoral Scholar: Khalid Rashid Staff Research Associate: Weihang Zhao Lab Manager: Nanping Wu Laboratory & Core Affiliations: The Radu laboratory operates within the CMINT program at the Jonsson Comprehensive Cancer Center, with ready access to UCLA’s preclinical imaging cores, flow cytometry facilities, and translational pathology resources. Collaborative ties span the departments of Molecular and Medical Pharmacology, Surgery, Radiological Sciences, and the Institute for Molecular Medicine.