جستجوی استاد راهنمای دانشگاهی

Professor Chris Thiemermann is a leading pharmacologist at Queen Mary University of London, serving as Centre Lead for Translational Medicine & Therapeutics at the William Harvey Research Institute since 2007. With 40 years of expertise in sepsis, traumatic shock, and ischaemia research, he co-leads the Organ Dysfunction and Protection Research Theme alongside Professor Karim Brohi, focusing on: Excessive inflammation and ischaemia in critical illness Gender-specific disease responses Aging-related tissue injury mechanisms Translatable interventions for organ protection Immuno-metabolic dysregulation in sepsis/diabetes/CKD His work bridges target discovery in animal models with clinical translation. As CEO of William Harvey Research Limited and trustee of multiple institutions, he maintains active academic and administrative roles. Current contact: c.thiemermann@qmul.ac.uk Scientific Recognition Academy of Medical Sciences Fellow Royal College of Physicians Fellow Foreign Fellow, Academia de Sciences de Lisboa

• Pathophysiology of shock (sepsis/trauma/ischaemia-reperfusion injury)
• Immuno-metabolic alterations in critical illness
• Organ dysfunction and protection mechanisms
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Professor Margaret Ashcroft is a Principal Investigator at the University of Cambridge, Department of Medicine, and affiliated with the Cambridge Immunology Network. Her research focuses on hypoxia signaling, mitochondrial biology, and their roles in cancer, angiogenesis, ischemia, and metabolism. Institution: University of Cambridge Department: Department of Medicine Research Trends: Her recent work explores mitochondrial gene regulation (e.g., CHCHD4) in tumour growth, hypoxia-induced metabolic adaptations, and HIF signaling in both cancer and viral contexts. Studies include ischemic tolerance mechanisms and mitochondrial disulfide relay systems. Scientific Focus: Key subfields include tumour cell viability under hypoxia, epithelial-mesenchymal transition, and hypoxia's role in viral replication (e.g., HIV). Her publications emphasize translational immunology and metabolic homeostasis.

• Angiogenesis
• Hypoxia
• Ischaemia
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Professor Martin Richards holds a Research Chair in the Department of Physical and Life Sciences at the University of Huddersfield, where he directs the Evolutionary Genomics Research Centre. Previously, he has held academic roles at UCL, Huddersfield, and Leeds University, focusing on human evolution and bioinformatics. His research expertise centers on archaeogenetics, particularly applying mitochondrial DNA (mtDNA) analysis to understand human migration patterns, including the settlement of Europe, Southeast Asia, and the Pacific. Key contributions include influential models on prehistoric dispersals and the use of mtDNA networks in phylogenetic analysis. Richards' educational background includes genetics studies at the Universities of Sheffield, Manchester, and Oxford. His work has coalesced around mtDNA genome variation, addressing questions such as the out-of-Africa dispersal routes and the genetic history of European populations. He co-edited *Mitochondrial DNA and the Evolution of Homo Sapiens* (2006) and has contributed to over 120 peer-reviewed publications, with a h-index of 62. Research interests span archaeogenetics, human evolution, and molecular evolution, with a focus on resolving debates around European settlement and Pacific colonization. Collaborations include the ACROSS project investigating Australasian colonization. Awards and recognitions include a Google Scholar h-index of 79 from 26,574 citations. Supervised PhD projects explore archaeogenetic topics, and he actively accepts new students in these areas. Richards' work contributes to UN Sustainable Development Goals, particularly through insights into human migration and genetic diversity. His lab, the Evolutionary Genomics Research Centre, serves as a hub for advanced genetic studies, integrating archaeological and genomic data to trace human prehistory.

• Genetics
• Archeogenetics
• Human Evolution
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Mark Crabtree is a University Research Lecturer and British Heart Foundation Intermediate Basic Science Research Fellow at the University of Oxford, leading the Channon Group focused on cardiovascular functional genomics and redox signaling. His research integrates metabolomic and proteomic approaches to study nitric oxide mechanisms in cardiovascular disease models. Education: BSc (Hons) from the University of Surrey (2001), followed by a collaborative PhD at the University of Surrey and Weill Medical College of Cornell University. Postdoctoral training under Professor Keith Channon began in 2006, supported by a BHF Centre of Research Excellence Transition Fellowship (2012–2015). Research interests include nitric oxide delivery systems for cardiovascular therapies, redox signaling in cardiac injury, and tetrahydrobiopterin's role in metabolic regulation. His work bridges nanomaterials development (e.g., graphene-based NO-releasing coatings) with clinical applications in ischemia-reperfusion injury and atherosclerosis. Notable contributions include advancements in pH-sensitive NO delivery systems and mechanistic insights into myocardial nitroso-redox imbalance post-cardiac surgery. He chairs the 2018 International Nitric Oxide Society Conference and serves on the society's council. Scientific awards: British Heart Foundation Intermediate Basic Science Research Fellowship. Active grants include BHF funding for redox signaling studies. His lab collaborates internationally, with recent publications spanning NO-based therapies, metabolic reprogramming in macrophages, and vascular biology.

• Cardiovascular Disease
• Nitric Oxide Signaling
• Redox Biology
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Dewar Finlay is a Professor of Electronic Systems and Head of the School of Engineering at Ulster University . He previously served as Research Director for the School of Engineering and Interim Associate Dean for Research & Impact within the Faculty of Computing, Engineering and the Built Environment. His work bridges healthcare technology and computational engineering. Education: BEng in Electronic Systems, Ulster University PhD in Computing, Ulster University Research Interests: His research focuses on healthcare technology with emphasis on computerised ECG analysis and deep learning applications in cardiology . He explores AI-driven diagnostics , signal processing , and medical device validation through projects like DTNet+ Digital Twin Network and IoT-Driven Cybersecurity Framework for Intrusion Detection in Drones . Scientific Awards: Best Poster (2024) - Calibrated Uncertainty AI in ECG Analysis Early Career Investigators Award (2022) - British Society for Heart Failure Grants & Collaborations: He has secured funding from EU Horizon 2020 , RCUK , DEL , and InvestNI . Current projects include AI-assisted echocardiography for congenital heart defects in Sub-Saharan Africa and federated learning frameworks for cardiac healthcare.

• Healthcare Technology
• Artificial Intelligence
• Digital Signal Processing
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Jesse Kigozi is an Associate Professor in the Health Economics Unit of the School of Applied Health Sciences, specializing in health economic evaluations within clinical trials for chronic disease management and primary care interventions. His core research domains include: Cost-effectiveness analysis of vascular revascularization strategies Opioid stewardship programs in primary care settings Optimal timing interventions for hypertensive disorders in pregnancy Musculoskeletal pain management and injection therapies Recent publications (2023-2025) reveal a concentrated focus on embedded health economic analyses within major multicenter trials like BASIL-2 (vascular surgery), PROMPPT (opioid management), and WILL (obstetric hypertension), emphasizing real-world resource allocation and patient-centered outcomes. Dr. Kigozi actively secures and manages research funding through the UK's National Institute for Health Research: Principal Investigator : TREADON trial (NIHR, 2022-2026) on plantar heel pain treatments Co-Investigator : COMBINER trial (bipolar disorder, 2024-2030), Medal Trial (low back pain, 2023-2028), PTABIT (thyroid tumors, 2022-2027) He collaborates extensively with interdisciplinary consortia including the BASIL-2 Investigators, PROMPPT Team, and HIT trial team, driving evidence-based practice through methodologically rigorous health services research.

• Health Economics
• Primary Care
• Randomized Controlled Trials
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Dr. Yalei Yang is an Honorary Research Associate at the School of Mathematics & Statistics, University of Glasgow. Their research focuses on medical imaging and statistical modeling, particularly in cardiovascular applications. They collaborate with experts in cardiology and biomedical engineering to develop advanced analytical frameworks for diagnostic imaging. Key research interests include Bayesian hierarchical modeling, spatio-temporal analysis of medical imaging data, and machine learning applications in cardiology. Their work integrates statistical methodologies with clinical challenges to improve diagnostic accuracy for conditions like myocardial ischaemia. Publications highlight contributions to DCE-MRI analysis for ischemia detection and myocardial perfusion classification using Markov Random Fields. These studies emphasize generalizable statistical models with clinical relevance. No grants or awards are explicitly listed, though their collaborative projects suggest active research engagement. No lab affiliations are specified in the provided text.

• Medical Imaging
• Bayesian Statistics
• Biomedical Engineering
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Robert J Hinchliffe serves as Clinical Professor of Vascular Surgery at Bristol Medical School, University of Bristol, and is affiliated with the Bristol Population Health Science Institute. His clinical and research expertise centers on vascular pathologies including abdominal aortic aneurysms, chronic limb-threatening ischaemia, and diabetic foot complications. His educational credentials include: MB ChB from University of Bristol MD from University of Nottingham Fellowship of the Royal College of Surgeons (FRCS) Hinchliffe's research program pioneers evidence-based vascular surgery through high-impact systematic reviews and randomized controlled trials. He investigates critical areas such as limb salvage strategies in critical ischaemia, diabetes-related foot disease management, and surgical oncology outcomes. His methodological rigor in clinical trial design and health economic analyses significantly influences vascular surgery guidelines and practice. Recent publication trends reveal growing emphasis on health economic evaluations of revascularization techniques and real-world adherence to diabetic foot care pathways. His work bridges clinical practice with health policy implementation, particularly through NICE guideline assessments. As active supervisor of graduate researchers, he contributes to vascular surgery education while leading three major funded projects: CAMELOT: Continuous rectus sheath analgesia in emergency laparotomy PROTECTOR: Perioperative tobacco cessation in vascular/cardiothoracic surgery Reporting frameworks for anaesthesia interventions in RCTs His laboratory work integrates with multidisciplinary vascular teams across Bristol's teaching hospitals, focusing on perioperative optimization and translational research in limb preservation.

• Vascular Surgery
• Abdominal Aortic Aneurysm
• Chronic Limb-Threatening Ischaemia
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Dr. Peter McCartney is an Honorary Clinical Fellow at the School of Cardiovascular & Metabolic Health, University of Glasgow. His research focuses on coronary artery disease, myocardial infarction, and interventional cardiology, with particular expertise in coronary microvascular function and percutaneous coronary intervention (PCI) optimization. He has contributed to landmark trials like CorMicA and T-TIME, investigating stratified medical therapy and adjunctive therapies in cardiovascular conditions. His work spans clinical trials, systematic reviews, and meta-analyses, addressing topics such as coronary perforation management, stent optimization, and microvascular injury assessment. McCartney collaborates widely, including with colleagues at the University of Glasgow and international institutions, to advance diagnostic and therapeutic strategies in cardiovascular medicine. No scientific awards are explicitly mentioned in the provided materials. His publications emphasize patient outcomes, procedural improvements, and invasive coronary function testing. He has been involved in designing trials evaluating therapies like mineralocorticoid receptor antagonists and low-dose intracoronary alteplase. No specific grants or lab affiliations are detailed in the text.

• Cardiology
• Cardiovascular Disease
• Interventional Cardiology
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Craig Lygate is an Associate Professor of Cardiovascular Physiology at the University of Oxford's Division of Cardiovascular Medicine, leading the 'Cardiac Energetics and Integrative Physiology' research group funded by the British Heart Foundation. His work focuses on understanding cardiac energy metabolism's role in health and disease, particularly exploring therapies for ischaemia and heart failure. He heads the Murine Cardiac Phenotyping Laboratory, using clinical techniques like echocardiography and MRI to assess genetically modified models. Education includes a BSc (Hons), MRes in Biological Sciences (University of Manchester), and a PhD in Cardiovascular Physiology (University of Glasgow). His research combines biochemical assays, cell culture, and collaborative approaches such as genomics and metabolomics, with a current emphasis on the creatine transporter and homoarginine's therapeutic potential. Recent articles highlight advancements in nitric oxide delivery systems for cardiovascular applications and the creatine kinase system's role in cardiac energy provision. Collaborations with Chemistry departments target novel treatments for ischaemia-reperfusion injury. No scientific awards are explicitly listed, but his work has been published in high-impact journals like Circulation and Clinical Science . He advises postgraduate researchers (e.g., Hannah Lake) and oversees grants focused on cardiac energetics. His lab integrates translational research, bridging molecular biology with clinical applications, aiming to translate findings into therapeutic strategies for cardiovascular diseases.

• Cardiac Physiology
• Cardiovascular Metabolism
• Heart Failure
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Lisa Heather is an Associate Professor and British Heart Foundation (BHF) Intermediate Fellow at the University of Oxford's Department of Physiology, Anatomy, and Genetics (DPAG) within the Medical Sciences Division. Her research focuses on cardiac metabolism in health and disease, particularly in diabetes and heart failure. She holds dual expertise in molecular mechanisms of metabolic dysfunction and translational cardiovascular research. Dr. Heather earned a Bachelor's degree in Medical Biochemistry from the University of Surrey and conducted doctoral research on cardiac hypertrophy's metabolic origins. Her postdoctoral work explored mitochondrial dysfunction in diabetic cardiomyopathy. Key career milestones include a Diabetes UK RD Lawrence Fellowship (2011) and a BHF Intermediate Fellowship (2018), supporting her investigations into lipid metabolism and hypoxia signaling in diabetic hearts. Her research interests span mitochondrial bioenergetics, fatty acid trafficking, hypoxia responses, and metabolic reprogramming in disease. She employs advanced techniques like hyperpolarized MRI and metabolomics to study real-time metabolic changes, with recent breakthroughs identifying novel roles for fatty acids in disrupting hypoxia signaling and cardiomyocyte function. Her publications (e.g., Diabetes , Physiological Reviews , JCI Insight ) highlight interdisciplinary approaches to metabolic disease. She leads the Heather Group, advancing therapies targeting metabolic pathways in heart failure and diabetes. Her work bridges basic science and clinical applications, emphasizing metabolic interventions for cardiovascular health.

• Cardiac Metabolism
• Diabetic Cardiomyopathy
• Mitochondrial Metabolism
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Professor Paul Riley is a leading academic in cardiovascular development and regenerative medicine. He holds roles as Professorial Fellow in Medicine at Jesus College, British Heart Foundation Professor of Regenerative Medicine, and Chair of Development and Cell Biology at the University of Oxford's Department of Physiology, Anatomy and Genetics. He also directs the Institute of Developmental & Regenerative Medicine. His research focuses on cardiac regeneration, lymphatic vasculature, and macrophage biology, with a particular interest in translating developmental mechanisms to adult heart repair. Paul has received prestigious awards, including the European Society of Cardiology's Outstanding Achievement Award (2008) and Fellowship of the Academy of Medical Sciences (2014). Education: BSc Zoology (Leeds, 1987-1990); PhD Zoology (UCL, 1992-1995) Positions: Postdoctoral training at Mount Sinai Hospital (Toronto) and Oxford, followed by roles at UCL-Institute of Child Health before moving to Oxford in 2011. His research interests include transcriptional control of heart development, congenital heart disease modeling, and stem cell-derived cardiac repair. He teaches undergraduate and postgraduate courses at Oxford and UCL, covering topics like cardiovascular development and stem cell biology. His lab investigates epicardial progenitor cells, cardiac lymphatics, and macrophage interactions in regeneration. Scientific achievements include discovering epicardial cell potential for heart regeneration and elucidating lymphatic roles in post-injury repair. His work bridges basic science and clinical applications, aiming to develop novel regenerative therapies for heart disease.

• Cardiovascular Development
• Regenerative Medicine
• Stem Cell Biology
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Professor Adam Timmis is a Professor of Clinical Cardiology at Queen Mary University of London's William Harvey Research Institute within the Faculty of Medicine and Dentistry. His academic roles include leadership positions at the National Institute for Cardiovascular Outcomes Research (NICOR), Myocardial Ischaemia National Audit Process (MINAP), and the Farr Institute. He pioneered the rapid access chest pain clinic model, influencing UK clinical practice, and chaired NICE guideline groups for stable chest pain and angina management. He holds an ORCID iD: 0000-0003-1419-112X. His research focuses on healthcare delivery systems and cardiovascular outcomes, utilizing national electronic health records. His collaborative group spans QMUL, UCL, LSHTM, and Bristol University, emphasizing evidence-based healthcare and NHS quality initiatives. He previously edited the journal Heart and currently leads the European Society of Cardiology's Quality of Care and Clinical Outcomes . Research interests include cardiovascular risk prediction (e.g., SCORE2 models), interventional cardiology mapping, SCOT-HEART trial outcomes, and global cardiovascular epidemiology. His work bridges clinical practice and policy, addressing disparities in care access and outcomes across Europe and beyond. Notable achievements include a 2009 BMJ award nomination for his group's contributions. His research is supported by Barts Charity, MRC, and NIHR grants. Collaborators include leading figures in cardiovascular outcomes research across UK institutions and international partners. His academic contributions extend to guideline development (NICE), audit processes (MINAP), and editorial leadership, ensuring translation of research into clinical practice and policy.

• Cardiology
• Cardiovascular Medicine
• Healthcare Outcomes Research
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Yining Chen is an Associate Professor in the Department of Statistics at the London School of Economics and Political Science (LSE). He holds a PhD in Statistics from the University of Cambridge (2014). His research focuses on statistical methodology, particularly in change-point detection, nonparametric estimation, and computational aspects of statistical methods. He also explores shape-constrained estimation and time series analysis. Dr. Chen has taught courses such as ST444 Computational Data Science and ST304 Time Series and Forecasting at LSE. He has contributed to interdisciplinary research in medical statistics, including work on kidney and liver transplantation outcomes. His software contributions include R packages like 'not', 'scar', and 'Sshaped', which implement his methodological advancements in statistical computing. His research has been published in top-tier journals such as the Journal of the Royal Statistical Society and Biometrika. Key areas of application span econometrics, actuarial science, and biomedical research. He actively engages in collaborative projects addressing practical data challenges across disciplines.

• Statistical Methodology
• Change-Point Detection
• Nonparametric Estimation
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Christopher Twine is an Honorary Professor of Vascular Surgery at Bristol Medical School, University of Bristol, and a Consultant Vascular Surgeon at North Bristol NHS Trust. He holds qualifications including FRCS, MD, MB BCh (dist), and BSc. His research focuses on peripheral arterial disease , chronic limb-threatening ischaemia , and antithrombotic therapies following endovascular interventions. He leads the NIHR HTA-funded CLARITY trial and collaborates on the PLACEMENT trial. Recent publications highlight trends in revascularization strategies , endovascular device analysis , and guideline-driven vascular trauma management . His work emphasizes evidence-based changes to national and international clinical practices. Twine serves as Systematic Review Section Editor for the European Journal of Vascular and Endovascular Surgery and chairs the ESVS antithrombotic guidelines committee. He co-leads the Aneurysm, Peripheral Arterial Disease, and Stroke unit for the MSc in Translational Cardiovascular Medicine.

• Peripheral Arterial Disease
• Vascular Surgery
• Antithrombotic Therapies
• +۳ مورد دیگر