معرفی
Professor Margaret Ashcroft is a Principal Investigator at the University of Cambridge, Department of Medicine, and affiliated with the Cambridge Immunology Network. Her research focuses on hypoxia signaling, mitochondrial biology, and their roles in cancer, angiogenesis, ischemia, and metabolism.
- Institution: University of Cambridge
- Department: Department of Medicine
Research Trends: Her recent work explores mitochondrial gene regulation (e.g., CHCHD4) in tumour growth, hypoxia-induced metabolic adaptations, and HIF signaling in both cancer and viral contexts. Studies include ischemic tolerance mechanisms and mitochondrial disulfide relay systems.
Scientific Focus: Key subfields include tumour cell viability under hypoxia, epithelial-mesenchymal transition, and hypoxia's role in viral replication (e.g., HIV). Her publications emphasize translational immunology and metabolic homeostasis.
