Joachim Fandrey

Prof. Joachim Fandrey serves as the Director of the Institute of Physiology at the University Hospital Essen, affiliated with the University of Duisburg-Essen. His research group investigates oxygen-dependent gene expression, focusing on hypoxia-inducible factors (HIF), cellular oxygen sensing mechanisms, and their roles in inflammation, angiogenesis, and tissue regeneration.

• Institution: University of Duisburg-Essen, Institute of Physiology
• Contact: Joachim.Fandrey@uni-due.de

Research Themes: The group explores how HIF complexes regulate gene expression under hypoxia, mechanisms of inflammatory reactions, cross-talk between hypoxia and cytokine signaling, and artificial oxygen carriers for clinical applications. Recent work includes studies on HHT (hereditary hemorrhagic telangiectasia) and DFG-funded projects.

Scientific Trends: Analysis of 15 recent publications reveals a focus on hypoxia signaling in immune cells, artificial oxygen carriers, neurogenesis after ischemia, and HIF's role in cancer, inflammation, and retinal metabolism. Key subfields include ciliary oxygen sensing, NK cell hypoxia adaptation, and erythropoietin regulation.

Training & Collaboration: The group includes postdocs, doctoral students, and technical staff (e.g., Anna Wrobeln, Tristan Leu, Sandra Winning, Yves Schild). They collaborate with institutions like the German Research Foundation (DFG) and participate in international symposia (e.g., Young Physiologists' Symposium).