جست‌وجوی استاد و پژوهشگر

Emily Goldbergمشاهده پروفایل

پژوهشگر

• Immunometabolism
• Aging
• Inflammation
• +۳ مورد دیگر

Emily Goldberg is a leading researcher at the University of California San Francisco, focusing on immune-metabolic interactions in aging. Her work explores mechanisms underlying age-related inflammation (inflammaging) and its role in chronic diseases such as insulin resistance, cardiovascular disorders, and Alzheimer’s disease. B.S., Biochemistry & Molecular Biology, University of Arizona (2008) Ph.D., Nutritional Science & Immunology, University of Arizona (2014) Postdoc, Immunometabolism, Yale University (2020) Her research integrates immunology and metabolism to identify strategies for healthspan extension, emphasizing ketone bodies, inflammasome regulation, and immune cell function in adipose tissue. She has pioneered studies on how metabolic pathways influence inflammatory responses during aging. Goldberg’s recent publications highlight her focus on epigenetic mechanisms, lipid metabolism, and immunometabolic countermeasures against infections and atherosclerosis. These works span disciplines including immunology, gerontology, and metabolic disease research. 2020 Chan Zuckerberg Investigator Award 2018 Society for Leukocyte Biology Trainee Award 2016 American Heart Association Postdoctoral Fellowship 2015 American Federation for Aging Research Postdoctoral Fellowship She has secured significant NIH funding (R00AG058801, K99AG058801) for projects on ketone bodies and age-related inflammation. Her collaborative work spans institutions and disciplines, addressing neurodegenerative diseases, diabetes, and immune senescence.

Erik Ullianمشاهده پروفایل

استاد

• Astrocyte Biology
• Neurodegenerative Diseases
• Synaptic Plasticity
• +۷ مورد دیگر

Erik Ullian is a Professor at the University of California San Francisco (UCSF), with a focus on neuroscience. His research spans astrocyte biology, synaptic plasticity, and neurodegenerative diseases, supported by prestigious awards such as the NIH New Innovator Award and Allen Distinguished Investigator Award. Education: BA in Biological Science (University of Chicago, 1991), PhD in Neuroscience (UCSF, 1997), Postdoc in Neurobiology (Stanford, 2004) His work explores astrocyte-neuron interactions, neuroinflammation, and mechanisms in Alzheimer's disease, ALS, and glioblastoma. Key methodologies include CRISPRi screening, brain organoids, and transcriptomic analysis. Recent publications highlight TDP-43 pathology in ALS, glucose metabolism restoration in Alzheimer's, and astrocyte roles in cancer suppression. Earlier contributions include neurodevelopmental studies on synaptic mapping and SARS-CoV-2 tropism for astrocytes. Scientific Awards Epilepsy training grant award (2001) Zaffaroni research fellowship in addiction research (2002) Sandler Award (2004) Alfred P. Sloan Fellowship (2005) March of Dimes Basil O’Connor Award (2006) Research to Prevent Blindness- New Investigator Award (2009) NIH New Innovator Award (2014) Walt and Lilly Disney Award for Amblyopia Research (2015) Allen Distinguished Investigator Award (2015)

Lucas Changمشاهده پروفایل

استادیار

• Immunometabolism
• T Cell Biology
• Cancer Immunology
• +۷ مورد دیگر

Lucas Chang is an Assistant Professor affiliated with the Jackson Laboratory (JAX) and the Graduate School of Biomedical Science and Engineering (GSBSE) at the University of Maine. His research is centered on immunometabolism, with a focus on understanding how metabolic pathways regulate immune cell behavior in disease contexts such as cancer and autoimmunity. He leads a laboratory investigating T cell reprogramming within the tumor microenvironment, bridging immunology, metabolism, oncology, and bioinformatics. Dr. Chang earned his D.Phil. (Ph.D.) from the University of Oxford in 2010. His work has consistently explored the metabolic regulation of immune cells, particularly T cells, and its implications for therapeutic interventions. His research interests lie at the intersection of immunology and metabolism, with specific emphasis on T cell metabolic reprogramming , immune cell fate , and metabolic competition in the tumor microenvironment . His lab investigates how cellular and molecular metabolic events control immune responses during disease progression, aiming to develop novel strategies for immunotherapy, drug development, and disease prognosis. His work has significant implications for cancer treatment and autoimmune disorders like lupus. His recent publications (2023–2025) demonstrate a sustained and impactful research trajectory, with primary research articles and reviews appearing in top-tier journals such as Cell , Immunity , and Nature Immunology . The articles reveal a consistent theme of dissecting the metabolic dependencies of immune cells—T cells, B cells, and dendritic cells—under stress conditions like glucose restriction or chronic activation, and how these pathways can be therapeutically targeted in cancer and autoimmune diseases. Dr. Chang has not been mentioned to have received specific scientific awards in the provided text. He is actively involved in research and mentorship, as evidenced by his primary authorship on recent publications and his role as a principal investigator. His lab develops and publishes detailed protocols, indicating a commitment to methodological rigor and scientific sharing. He collaborates with a broad network of researchers across institutions. His laboratory, referred to as the 'Chang Bio' lab, is actively engaged in research on immune cell metabolism, utilizing advanced techniques like the Seahorse Extracellular Flux Analyzer for bioenergetic profiling and transcriptomic analysis to understand metabolic pathways in health and disease.

Caroline Nordenvallمشاهده پروفایل

دانشیار

• Surgical Treatment of Inflammatory Bowel Disease (IBD)
• Colorectal Cancer
• Translational Research
• +۱۲ مورد دیگر

Caroline Nordenvall is an Associate Professor and clinically active colorectal surgeon at Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. She leads the Colorectal Surgery research group and focuses on epidemiological and clinical studies related to inflammatory bowel disease (IBD) and colorectal cancer. Nordenvall heads the Swedish quality register for IBD patients and is a board member of the National Working Group for IBD (NAG-IBD). Board-certified surgeon (2016) Associate Professor of Surgery (2016) PhD in Medical Epidemiology and Biostatistics (2010) Medical Degree (2006) Her research includes the CRUISE study (Colectomy and Reconstruction in Ulcerative colitis in Sweden and England) and the CIM-IBD study (immunological analyses of IBD resectates). She also works on registry-based studies through CRCBaSe and Megalinking , and clinical trials like Stockholm III and ALASCCA . She supervises 11 PhD students and 3 postdocs. Nordenvall has received research funding from the Swedish Society for Medical Research (SSMF), Ihre Fellowship, and Region Stockholm. Recent awards include the Regional Prize of Stora Forskarpriset and the Bengt Ihre Scholarship 2024 , recognizing her contributions to IBD surgery and colorectal research.

Susanne Schlisioمشاهده پروفایل

مدرس ارشد

• Oxygen Sensing
• Cancer Biology
• Neuroblastoma
• +۵ مورد دیگر

Susanne Schlisio is a Senior Lecturer (Docent) at the Department of Oncology-Pathology, Karolinska Institutet , where she has been faculty since 2017 and Senior Lecturer since 2023. Her research focuses on oxygen-sensing pathways in cancer, particularly neuroblastoma and pheochromocytoma of the sympathoadrenal lineage, intratumor heterogeneity, and mitochondrial metabolism. Education: PhD in Cancer Research (2002, Duke University); Postdoctoral Researcher (2008, Dana-Farber Cancer Institute/Harvard Medical School). Research Highlights: She investigates how oxygen deprivation (hypoxia) drives cancer via altered oxygen-sensing mechanisms, utilizing single-nuclei transcriptomics, spatial sequencing, and novel mouse models to dissect tumor heterogeneity and identify differentiation strategies for therapy. Her work links hypoxia to mitochondrial dysfunction in VHL syndrome and defines cellular identities correlating with neuroblastoma clinical outcomes. Awards and Grants: Recipient of the ERC Synergy Grant (2019) , senior funding from the Swedish Cancer Foundation (2017), Ludwig Cancer Institute (2008), and multiple postdoctoral fellowships. Her lab collaborates with SciLifeLab and Mats Nilson’s group for spatial transcriptomics. Scientific Impact: Work on oxygen-sensing pathways in Kaelin’s lab contributed to the Nobel Prize in Physiology or Medicine .

• Neurodegenerative Diseases
• Motor Neuron Biology
• Genetic Disorders
• +۵ مورد دیگر

Dr. James Orengo, Associate Professor at Baylor College of Medicine and Director of the Multi-disciplinary ALS Clinic at Michael E. DeBakey VA Medical Center, focuses his research on motor neuron degeneration in neurodegenerative diseases like Spinocerebellar Ataxia Type 1 (SCA1) and ALS . His lab employs mouse models , transgenic zebrafish lines , and human iNeurons to investigate disease mechanisms. Key research areas include: Pathogenic drivers of bulbar dysfunction in SCA1 Transcriptomics of motor neuron degeneration Cross-species modeling (Human, Mouse, Zebrafish) Collaborations with the Undiagnosed Diseases Network (UDN) Dr. Orengo also contributes to clinical care through the BCM ALS Clinic and co-leads multidisciplinary teams at the Michael E. DeBakey VA Medical Center . His lab develops tools for CRISPRi screens and live imaging in zebrafish to accelerate therapeutic discovery.

Steve N. Georasمشاهده پروفایل

استاد

• Pulmonary and Critical Care Medicine
• Asthma
• Immune Cell Activation in the Lung
• +۱۱ مورد دیگر

Steve N. Georas, M.D., is a Professor at the University of Rochester Medical Center (URMC) in the School of Medicine and Dentistry, with primary appointments in the Department of Medicine (Pulmonary Diseases and Critical Care), and joint appointments in Environmental Medicine and Microbiology and Immunology. He is a board-certified specialist in Pulmonary and Critical Care Medicine, actively practicing at the Mary Parkes Center for Asthma, Allergy & Pulmonary Care, and serving as an attending physician in the Medical Intensive Care Units at Strong Memorial and Highland Hospitals. His research is centered on the immunological mechanisms of asthma and lung inflammation. Key areas include epithelial barrier dysfunction , type 2 immune responses , the role of lysophosphatidic acid (LPA) and autotaxin , and the impact of air pollution and environmental exposures on lung health. He leads the Study of Asthma in Rochester (SOAR2) and is involved in the national PrecISE asthma network. His recent publications highlight a strong focus on asthma pathogenesis, the use and de-escalation of biologic therapies, the effects of environmental factors like air pollution and climate change on asthma, and the critical issue of race-based interpretation of pulmonary function tests, advocating for more equitable diagnostic practices. His work spans basic science, translational research, and clinical trials. Scientific Awards: Walter & Carmina Mary Parkes Family Distinguished Professorship Research and Mentoring: Dr. Georas directs an active research laboratory investigating immune cell activation in the lung. He mentors postdoctoral fellows (Maggie Connolly, Patrick Donohue), research staff (Kyle Norton), and graduate students (Traci Pressley). His lab is involved in multiple clinical trials and has received significant grant funding for research on lung disease and environmental health. Research Lab: The Georas Lab at URMC is dedicated to understanding airway inflammation and lung function in asthma, with specific projects on epithelial barrier dysfunction, airway oscillometry, and the implications of race in pulmonary function testing.

Ryan A Harrisمشاهده پروفایل

دانشیار

• Vascular Physiology
• Exercise Physiology
• Cardiovascular Disease
• +۵ مورد دیگر

Ryan A Harris serves as Associate Professor at Augusta University's Medical College of Georgia with appointments across the Department of Medicine, Population Health Science, Pediatrics, and Physiology. He directs the Laboratory of Integrative Vascular and Exercise Physiology (LIVEP) and holds the title of Associate Director within the Georgia Prevention Institute. Education: Ph.D. in Exercise Physiology, Indiana University (2007) M.S. in Kinesiology and Exercise Science, California State University (2002) B.S. in Kinesiology and Exercise Science, San Diego State University (1999) Harris's research centers on vascular dysfunction mechanisms in clinical populations including cystic fibrosis, COPD, diabetes, and hypertension. His work investigates endothelial dysfunction through flow-mediated dilation measurements, oxidative stress pathways, and sex-specific responses to vascular stressors. Current projects explore estrogen's cardioprotective role, endothelin receptor function, and vascular impacts of cancer therapies. His most recent publications reveal emerging trends in cardio-oncology (particularly prostate/breast cancer vascular complications), racial disparities in microvascular function, and novel exercise interventions for cystic fibrosis. Key themes include endothelial dysfunction as a cross-cutting mechanism in chronic diseases, the role of oxidative stress in exercise intolerance, and precision approaches to vascular assessment. Scientific Awards: ACSM Fellowship (2012) NIH Loan Repayment Award (2010) Exemplary Teaching Awards (2015, 2017) Emerging Scientist Award (2014) Outstanding Young Faculty Award (2014) Harris leads multiple NIH-funded projects including R01 mechanisms studying vascular dysfunction in cystic fibrosis and COPD. He mentors graduate students within LIVEP while serving on university committees including the Faculty Senate Executive Committee and NIH PRIDE Mentorship program. His editorial roles span Journal of Applied Physiology and Medicine & Science in Sports & Exercise. The LIVEP laboratory (600 sq ft) houses advanced equipment including GE Logiq ultrasound systems, metabolic carts, and arterial stiffness measurement devices. Current research teams focus on cystic fibrosis vascular function, cancer-related cardiovascular complications, and hypertension mechanisms through the Stress Related Mechanisms of Hypertension Risk program (P01HL069999).

• Obstetrics
• Maternal and Fetal Medicine
• Reproductive Medicine
• +۶ مورد دیگر

Dr. Sara Hillman is an Associate Professor and Honorary Consultant in Obstetrics and Maternal and Fetal Medicine at University College London. Her work bridges clinical practice with research in reproductive health, genetics, and maternal-fetal interactions. University: University College London Emails: sara.hillman@ucl.ac.uk, sara.hillman@nhs.net Research Interests: Her research spans obstetrics, placental biology, maternal-fetal medicine, and global health disparities. Key areas include: Preeclampsia and fetal growth restriction Genomic and proteomic profiling in pregnancy complications Diabetes and metabolic disorders during gestation Health policy impacts on maternal care equity Digital health tools for prenatal monitoring Recent Publications: Highlighting placental dysfunction, maternal immunity, and the impact of public policies on vulnerable populations. Her work integrates molecular biology with clinical and social determinants of maternal-fetal health.

• Hypermobility Spectrum Disorders
• Ehlers-Danlos Syndromes
• Dysautonomia
• +۵ مورد دیگر

Jane Simmonds is a Teaching Professor in the Infection, Immunity & Inflammation Department at University College London's Institute of Child Health. She serves as Director of Education at Great Ormond Street Institute of Child Health and leads the MSc Advanced Paediatric Physiotherapy program. Her clinical role includes being physiotherapy clinical lead at Central Health Physiotherapy's London Hypermobility Unit. Her research focuses on hypermobility spectrum disorders, Ehlers-Danlos syndromes, dysautonomia, and pediatric physiotherapy. She has developed assessment tools like The Spider questionnaire and led the PULSE study on postural tachycardia syndrome rehabilitation. Her work emphasizes multisystemic approaches to hypermobility-related disorders across the lifespan. Recent publications demonstrate a strong trend in developing and validating clinical assessment tools, investigating exercise rehabilitation protocols for dysautonomia, and establishing international consensus guidelines. Her work bridges clinical practice with research through co-creation methodologies involving patients and multidisciplinary teams. Community Champion Award (Ehlers-Danlos Society, 2023) Pioneer in EDS and HSD Clinical Care (Ehlers Danlos Society, 2022) Vice Chancellors Education Award (UCL, 2019) Research Facilitation Award (Musculoskeletal Association, 2012) Professor Simmonds has secured over £400,000 in research and education grants, supervising more than 100 MSc projects and several PhD students. She chairs the AHP International Ehlers Danlos Consortium working group and serves as physiotherapy representative on the international Ehlers Danlos Syndrome Society medical board. Her educational leadership includes developing international courses through the Ehlers Danlos Society ECHO program and serving as an external examiner. She leads collaborative research teams focused on hypermobility disorders, working with institutions across the UK, Australia, and internationally. Current initiatives include the PULSE study implementation and expanding The Spider assessment tool for global clinical use.

• Regenerative Medicine
• Immunogenicity
• Stem Cell Research
• +۵ مورد دیگر

Dr. Sandra Petrus-Reurer is a Research Fellow at the University of Cambridge affiliated with Darwin College. Her work focuses on the immunogenicity of stem cell-derived cellular therapies, particularly in regenerative medicine applications for liver and retinal diseases. University: University of Cambridge Academic Rank: Research Fellow Research Interests: Dr. Petrus-Reurer specializes in evaluating immune responses to stem cell-based therapies. Her studies address challenges in organoid technology , HLA engineering , and preclinical modeling for treating cholangiopathies and age-related macular degeneration (AMD). Key areas include gene editing to reduce immunogenicity, differentiation protocols for retinal pigment epithelial cells, and vascular tissue engineering . Publication Trends: Her 15 most recent articles (2012–2025) demonstrate expertise in stem cell immunogenicity , retinal repair , and liver organoid development . She has pioneered HLA-mismatched therapies , Xeno-free differentiation protocols , and large animal models for preclinical validation. Notable work includes studies on complement factor H in AMD and endothelial-pericyte co-differentiation . Advising and Grants: No explicit information is available about students, advising roles, or grant funding in the provided texts. Labs and Teams: No specific details about labs, teams, or collaborative networks are mentioned.

• Cellular Neurophysiology
• Glial Physiology
• Neurodegenerative Diseases
• +۶ مورد دیگر

Professor Alexej Verkhratsky is a leading scholar at the University of Manchester , holding the Professor of Neurophysiology position in the Division of Neuroscience. With over 400 peer-reviewed publications and an H-index of 86, he is a globally recognized expert in glial physiology and neurodegenerative diseases. Member of Academia Europaea (Vice-President, Life Sciences) Elected to German National Academy of Sciences Leopoldina (2013) Highly Cited Researcher (2023) His research focuses on neuroglial communication , pioneering discoveries in calcium and sodium signaling in astrocytes and microglia. Key contributions include: Foundational work on glial excitability via Ca²⁺/Na⁺ dynamics Development of the astroglial cradle concept for synaptic regulation Identification of astroglial atrophy as an early marker in Alzheimer's disease Characterization of glial paralysis in neurodegeneration Caffeine-induced Ca²⁺ release mechanisms Role of P2X receptors in gliotransmission Recent publications (2025-2026) highlight his work on: Mitochondrial responses in Alzheimer's and tauopathies Glial regulation of cerebrospinal fluid dynamics Neurodegenerative mechanisms in white matter pathology Scientific Awards include: Copernicus Gold Medal (2017) Dana Alliance for Brain Initiatives (2012) Multiple academy memberships (Slovenian Academy of Sciences, Real Academia Nacional de Farmacia, Poland National Academy of Sciences) As Editor-in-Chief of Cell Calcium and Deputy Editor of Cell Death and Disease , he shapes discourse in glial physiology and neurodegeneration research. His work contributes to UN Sustainable Development Goals for brain health research.

Scott Nicholas Furlanمشاهده پروفایل

استادیار

• Graft-versus-host disease
• Hematopoietic cell transplantation
• T-cell therapy
• +۳ مورد دیگر

Dr. Scott Nicholas Furlan is an Assistant Professor in the Translational Science and Therapeutics Division at Fred Hutchinson Cancer Center, with a secondary appointment as Assistant Professor in the Department of Pediatrics at the University of Washington School of Medicine. He is a member of the Immunotherapy Integrated Research Center (IIRC) and Translational Data Science Integrated Research Center (TDS IRC) at Fred Hutch. His clinical expertise includes hematopoietic cell transplantation, pediatric oncology, and acute myelogenous leukemia. Education: Post-doctoral Fellowship in Transplant Immunology, Seattle Children’s Research Institute (2012-2015) Fellowship in Pediatric Hematology Oncology, UT Southwestern Medical Center (2009-2012) Residency in Pediatrics, UT Southwestern Medical Center (2006-2009) MD, Keck School of Medicine at USC (2002-2006) Bachelor of Arts, Macalester College (1994-1998) Research Focus: Dr. Furlan employs single-cell genomics to study immune reconstitution after hematopoietic cell transplantation and cellular immunotherapies for pediatric cancers. His lab investigates graft-versus-host disease mechanisms, T-cell dysfunction, leukemia biology, and tumor microenvironments, with emphasis on translational applications for improving clinical outcomes. Publication Trends: Recent work (2023-2025) focuses on immunogenomics of transplantation, cellular therapies, and tumor biology. Key themes include T-cell exhaustion, microbiota-immune interactions, epigenetic profiling, and novel immunotherapy targets. Studies frequently integrate computational biology with translational models. Clinical & Lab Leadership: Dr. Furlan leads the Furlan Lab at Fred Hutch, which develops computational tools for single-cell analysis and conducts research in pediatric malignancies. He oversees clinical trials investigating tumor heterogeneity in leukemia and Ewing sarcoma.

Jeremy Bornigerمشاهده پروفایل

استادیار

• Cancer Neuroscience
• Brain-Body Communication
• Neuroimmunology
• +۴ مورد دیگر

Jeremy Borniger is an Assistant Professor at Cold Spring Harbor Laboratory (CSHL) and leads the Borniger Laboratory , a member of the Cancer Center . His research pioneers the emerging field of cancer neuroscience , focusing on bidirectional communication between the brain and tumors, particularly how cancer disrupts sleep, metabolism, and immune function. Education : Ph.D. in Neuroscience (The Ohio State University, 2017), B.A. in Biological Anthropology (Indiana University, 2011). Postdoctoral Training : Stanford University (2017-2019) under Luis de Lecea. His work employs systems neuroscience techniques (optogenetics, calcium imaging, behavioral assays) to dissect tumor-brain interactions. Recent studies highlight hypocretin/orexin neurons as mediators of cancer-associated sleep disruption and glucose metabolism. He also explores bioelectronic medicine to manipulate neural circuits for tumor control. His 15 most recent publications (2025-2020) span neuroimmunology , circadian biology , and tumor physiology , with a focus on sensory nerve reprogramming, sleep fragmentation, and hypothalamic-pituitary-adrenal (HPA) axis dysfunction in cancer. Awards : NARSAD Young Investigator Award (2019), W.C. Young Recent Graduate Award (2018), Pelotonia Fellowship (2015). Professional Activities : Scientific consultant (Acuta Capital LLC, 2019-2020), founder of NeuroPhDee Twitch stream, and contributor to public science education via Skype a Scientist and Knowingneurons.com .

• Cardiovascular Physiology
• Molecular Endocrinology
• Neuroimmunology
• +۳ مورد دیگر

Dr. Michael Madziva serves as a Lecturer in the Department of Physiology at the University of the Witwatersrand (Wits), Johannesburg. Holding a PhD from the University of Cambridge alongside BSc and MSc qualifications, he maintains an active research program utilizing rodent and avian models to investigate physiological mechanisms across multiple systems. His academic credentials include: Bachelor of Science (BSc) Master of Science (MSc) Doctor of Philosophy (PhD) from the University of Cambridge Dr. Madziva's research spans cardiovascular physiology, molecular endocrinology, neuroimmunology, and nanomedicine. He investigates cardiac function under pharmacological interventions (e.g., metformin in heart failure models), GnRH receptor structure and signaling pathways, fever induction mechanisms in the brain, and dietary impacts on bone health and erythrocyte integrity. His nanomedicine work develops curdlan-conjugated PLGA nanoparticles for macrophage activation and drug delivery applications, demonstrating translational potential. Analysis of his publication trajectory reveals sustained focus on G protein-coupled receptor (GPCR) biology since 2000, with increasing emphasis on cardiovascular and metabolic disorders in recent years. His 2022 work on metformin's cardioprotective effects exemplifies his translational approach, while earlier studies established foundational knowledge of receptor internalization mechanisms. This progression highlights integration of molecular techniques with whole-animal physiology. No scientific awards were documented in the source material. The available information contains no details regarding graduate students supervised by Dr. Madziva or specific research grants secured for his laboratory.