جست‌وجوی استاد و پژوهشگر

Sheng Yang Heمشاهده پروفایل

استاد

• Plant-Microbe Interactions
• Microbial Pathogenesis
• Plant Immunity
• +۳ مورد دیگر

Sheng Yang He is the Benjamin E. Powell Distinguished Professor of Biology at Duke University, with joint appointments in Cell Biology. He leads the He Lab, focusing on molecular mechanisms of plant immunity against microbial pathogens, particularly the interplay between host-microbe interactions and environmental factors like climate change. His research bridges plant pathology, microbiology, and systems biology. Education: PhD in Plant Pathology from Cornell University (1991), followed by faculty roles at the University of Kentucky and Michigan State University (1995–2020) before joining Duke in 2020. He is a Howard Hughes Medical Institute Investigator (2011–2024) and a member of the U.S. National Academy of Sciences (2015). Research Interests: Host defense mechanisms, bacterial effector proteins, stomatal immunity, microbiome dynamics, and climate resilience in crops. Recent work addresses how temperature and humidity influence plant-pathogen interactions and microbiome composition. Grants & Awards: Received HHMI funding renewal (2024–2031), Clarivate Highly Cited Researcher (2021–2024), and recognition for pioneering studies on Pseudomonas syringae pathogenesis and Arabidopsis immunity. His lab has produced over 200 peer-reviewed articles. Advising & Mentoring: Guided over 20 PhD students and postdocs, many of whom now lead academic or industrial research groups. Notable advisees include Brad Paasch (Sandia National Labs), Jonghum Kim (POSTECH), and Li Zhang (Soochow University). Labs & Teams: The He Lab at Duke collaborates with institutions globally, focusing on interdisciplinary approaches to combat crop diseases. Current projects include engineering climate-resilient plant immunity and microbiome-based disease prevention strategies.

Jared Bardمشاهده پروفایل

استادیار

• Cellular Stress Responses
• Biomolecular Condensation
• Stress Granules
• +۴ مورد دیگر

Jared Bard is an Assistant Professor at Texas A&M University, leading the Bard Lab. His research focuses on cellular stress responses, particularly stress-induced translational reprogramming and biomolecular condensation. He investigates how cells reorganize under stress, using viral infections and cancer cell models. His work combines biophysical, biochemical, and high-throughput approaches to uncover molecular mechanisms. Education: B.Sc., Molecular Biophysics and Biochemistry, Yale University (2012) Ph.D., Molecular and Cell Biology, University of California Berkeley (2018) Postdoctoral Research, University of Chicago (2018–2023) Research Interests: Stress-induced mRNA condensation mechanisms Role of stress granules in viral replication and cancer resistance Proteasome function in stress response Chaperone regulation of biomolecular condensates Lab Activities: The Bard Lab uses Chikungunya virus and cancer cell stress resistance as models to study how stress granules aid viral replication and drug resistance. Recent work highlights adaptive condensation responses conserved across species and the role of chaperones in condensate preservation.

Stephen Attwoodمشاهده پروفایل

پژوهشگر

• Epidemiology
• Infectious Diseases
• Genetic Variation Analysis
• +۴ مورد دیگر

Dr. Stephen Attwood is a Post Doc Researcher in the Pybus group at the Natural History Museum, London, and a Scientific Associate at the same institution. He was formerly a Professor of Epidemiology at West China Medical School. His research focuses on evolutionary approaches to infectious disease epidemiology, including SARS-CoV-2 lineage tracking via the Pango nomenclature system and evaluating public health interventions. He has also contributed to understanding schistosomiasis evolution, describing three new species and identifying Mekong schistosomiasis in new regions. His work integrates genetic variation analysis, phylogenetics, and ecological studies to address disease emergence and biodiversity impacts of infrastructure like dams. Research interests span epidemiological modeling, pathogen evolution, and parasitology, with a focus on applying genetic data to real-world public health challenges. Key areas include SARS-CoV-2 transmission dynamics, schistosome taxonomy, and the ecological consequences of human activities on freshwater ecosystems. His articles explore topics ranging from viral mutation impacts on vaccine efficacy to schistosome mitochondrial genome divergence, reflecting a dual focus on contemporary pandemics and long-term parasitic disease evolution. Grants and advising details are not explicitly listed, but his lab affiliations include the Evolve.Zoo group and collaborations with global health institutions. Labs/Teams: Active in the Evolve.Zoo research lab, focusing on evolutionary biology and disease systems.

John Misasiمشاهده پروفایل

استادیار

• Virology
• Immunology
• Antibody Discovery
• +۴ مورد دیگر

Dr. John Misasi is an Assistant Professor at Boston University's Chobanian & Avedisian School of Medicine, specializing in Virology, Immunology, and Microbiology. He holds an MD from SUNY Upstate Medical University and a BS from Boston University. His research focuses on antibody discovery, viral pathogenesis, and structural biology. He has contributed to the development of FDA-approved Ebola therapies like mAb114 and leads studies on SARS-CoV-2, MPOX, and Lassa viruses. Dr. Misasi's lab investigates immune evasion mechanisms and antibody-mediated immunity at the National Emerging Infectious Disease Laboratory. He has been recognized with awards including the NIH Director’s Award and multiple NIAID Merit Awards. Education: MD: State University of New York Upstate Medical University BS: Boston University Research Interests: Dr. Misasi's work centers on understanding antibody mechanisms against high-containment pathogens. His lab uses virology, immunology, and structural biology tools to study viral entry pathways, neutralizing antibodies, and immune evasion strategies. Key areas include: Antibody engineering for SARS-CoV-2 and Ebola Vaccine design targeting viral glycoproteins Host-pathogen interactions in filoviruses Therapeutic antibody development Grants & Awards: National Institutes of Health Director’s Award (2020) NIAID Merit Award for Ebola Outbreak Response (2018) Vaccine Research Center Staff Recognition (2018) NIH UGSP and INRO Mentorship Programs (2019-2023) Labs & Teams: He leads the National Emerging Infectious Disease Laboratory (NEIDL) team focusing on high-containment pathogens. Collaborations include work at NIH Vaccine Research Center and Harvard Medical School.

• Nanomedicine
• Targeted Drug Delivery Systems
• Antimicrobial Peptides
• +۷ مورد دیگر

Rohan Shah is a Lecturer at Swinburne University of Technology's Department of Chemistry and Biotechnology, School of Science, Computing and Emerging Technologies. He holds a PhD from Swinburne, supported by the Victoria-India Doctoral Scholarship, and was awarded the Sparrho Early Career Researcher Prize for lipid nanoparticle work. His research focuses on nanomedicine, antimicrobial peptides, and sustainable biotechnology solutions for global health challenges. He has held academic roles at Swinburne and RMIT, including Lecturer and Academic Tutor, and is a registered pharmacist and Chartered Member of the Royal Australian Chemical Institute (RACI). Dr. Shah's research explores targeted drug delivery systems, systems biology, and metabolomics applications in food and environmental science. He has secured significant grants (e.g., $1.2M+ in external funding) and collaborates globally. His editorial roles include Frontiers in Sustainable Food Systems, Metabolites, and Food Science and Nutrition Cases. He has authored over 100 publications, with recent work addressing PFAS toxicity in wildlife, food additive health impacts, and nanoformulated drug delivery. Professional activities include serving as Treasurer of the RACI's Early Career Chemists Group and committee roles in the Young Chemists Group. His work spans 15+ years of grants, 99+ publications, and supervision of four HDR students. He advocates for food additive reformulation, sustainable technologies, and improved drug delivery systems.

Shoib Siddiquiمشاهده پروفایل

مدرس ارشد

• Cancer Biology
• Immunology
• Glycobiology
• +۴ مورد دیگر

Dr. Shoib Siddiqui is a Senior Lecturer at the University of Hertfordshire's School of Life and Medical Sciences, specializing in cancer biology, immunology, and glycobiology. Previously, he held positions at the American University of Ras Al Khaimah and conducted postdoctoral research at UC San Diego under Prof. Ajit Varki. His research focuses on sialic acids, Siglecs, and microRNA mechanisms in cancer, Alzheimer’s, and sepsis. He earned his Ph.D. from ETH Zurich, investigating neuropilin-2 in skin cancer progression. Education: Ph.D. in Vascular Biology, Immunology, and Cancer Biology (ETH Zurich, 2009–2013) M.Sc. in Biotechnology (IIT Bombay, 2008) Research Focus: Dr. Siddiqui’s work explores cancer progression pathways, tumor biomarkers, and novel therapies. Key areas include Siglec-sialoglycan interactions, microRNA targeting, and drug repurposing for colorectal cancer. His recent projects involve developing RNAi therapeutics and inhibitors for Siglec-15. Projects: Fluralaner as a Colorectal Cancer Therapeutic (2026–2027) ADAMTS-7 Inhibition for Coronary Artery Disease (2022) UK-China Mycotoxin Reduction Alliance (2022–2023) Publications: Over 39 peer-reviewed articles in journals like Journal of Clinical Investigation , PNAS , and Blood , with a focus on oncology, glycobiology, and immunology. Recent trends emphasize Siglec-targeted therapies, microRNA networks, and drug repurposing strategies. Awards: No formal awards listed, but noted for impactful publications in high-impact journals. Advising & Grants: Served as Principal Investigator (PI) on RNAi therapeutics and Co-Investigator (CoI) on Siglec-15 and ADAMTS-7 projects. Collaborations span international institutions and cross-disciplinary teams. Labs/Teams: Active in the Biosciences Research Group and Centre for Research in Mechanisms of Disease and Drug Discovery at UH. Collaborates with global researchers in glycobiology and oncology.

• Virology
• HIV Research
• Vaccine Development
• +۳ مورد دیگر

Stephen Dewhurst, Ph.D., is Vice President for Research and Chief Research Officer at the University of Rochester (UR) and Vice Dean for Research at the UR School of Medicine and Dentistry (SMD). He holds a professorship in the Department of Microbiology and Immunology (SMD). His administrative roles include former department chair (2009–2021), SMD Senior Associate Dean for Basic Research (2007–2009), and codirector of UR’s Center for AIDS Research (2008–2020). Dr. Dewhurst’s research focuses on virology, with 30+ years’ experience including HIV neuropathogenesis, vaccine development, and innate immune responses. He leads NIH-funded programs in graduate education and Deaf postdoctoral training. His mentorship has guided 29 Ph.D. students, 16 postdoctoral fellows, and >100 undergraduates, earning awards like the William H. Riker Award (2008) for graduate education. Key scientific contributions include HIV humanized mouse models, antiviral therapeutics, and MLK inhibitors for neuroinflammation. His patents span viral vectors, integrin-binding monobodies, and influenza vaccines. Awards include membership on NIH study sections (e.g., HIV Immunopathogenesis) and editorial roles in virology journals.

Yoshihiro Kawaokaمشاهده پروفایل

استاد

• Virology
• Influenza Virus
• Ebola Virus
• +۷ مورد دیگر

Yoshihiro Kawaoka is a Professor in the Department of Pathobiological Sciences at the School of Veterinary Medicine, University of Wisconsin–Madison. His research focuses on the molecular mechanisms of interspecies transmission and pathogenesis of influenza and Ebola viruses, with significant contributions to understanding pandemic risks and viral evolution. His research interests include: Molecular pathogenesis of influenza in poultry and mammals Interspecies transmission of influenza viruses Role of viral proteins in Ebola virus replication and pathogenesis Development of reverse genetics systems for RNA viruses Host receptor specificity and viral adaptation The recent publications highlight a strong focus on influenza A virus (particularly H5N1 and H9N2 strains) and Ebola virus, with recurring themes in viral entry, host adaptation, glycoprotein function, and pathogenicity determinants. The work integrates molecular virology, structural analysis, and host-pathogen interactions. Notable scientific contributions include: Elucidating the molecular basis of high virulence in H5N1 influenza viruses Developing plasmid-based systems for generating infectious influenza viruses Characterizing the role of Ebola virus glycoprotein in cell entry and immune modulation Demonstrating receptor specificity differences in avian and mammalian hosts Kawaoka has advised numerous students and mentored researchers in virology, though specific names are not listed. His lab has secured funding for Ebola vaccine and antiviral research, as evidenced by public appeals for donations. He teaches Veterinary Virology, a clinically oriented course covering pathogenesis, diagnosis, and management of viral diseases in animals. His team operates within the Department of Pathobiological Sciences, contributing to both basic and applied virology research with implications for global health and pandemic preparedness.

Laura Knollمشاهده پروفایل

استاد

• Medical Microbiology
• Immunology
• Parasitology
• +۱۴ مورد دیگر

Laura Knoll is a Professor in the Department of Medical Microbiology and Immunology at the University of Wisconsin–Madison, School of Medicine and Public Health. Her research focuses on the molecular mechanisms of protozoan parasite pathogenesis, particularly Toxoplasma gondii , Cryptosporidium parvum , and Entamoeba histolytica . She leads a dynamic research laboratory that employs cutting-edge technologies including next-generation sequencing, mass spectrometry, multi-omics, and organoid models. B.A. in Chemistry and Biology, Saint Olaf College (1989) Ph.D., Washington University School of Medicine (1994) Postdoctoral Research, Stanford University Dr. Knoll's research spans several key areas: host-pathogen interactions, chronic infection mechanisms, microbial metabolism, and the role of host immune genes such as IFN-γ and ZBP1 in infection outcomes. Her lab has pioneered the use of organoids to study parasite development and has developed novel animal models for Entamoeba histolytica infection. Her work integrates molecular, biochemical, and immunological approaches to dissect how parasite and host genes influence infection dynamics. The recent publications from her lab reflect a strong trend in understanding metabolic manipulation by parasites, host lipid signaling, and the development of advanced in vitro and in vivo models. Her work increasingly leverages multi-omics to uncover regulatory networks in both host and pathogen during acute and chronic stages of infection. Dr. Knoll has received numerous scientific awards recognizing her contributions to parasitology and infectious disease research: 2024: UW-Madison Kellett Mid-Career Award 2022: William Trager Award for Basic Parasitology (ACMCIP) 2012: WARF Romnes Faculty Fellow 2009: Hartwell Foundation Biomedical Research Award 2008: American Heart Association Established Investigator Award 2007: American Cancer Society Research Scholar Award 2003: Shaw Scientist Award 2000: Burroughs Wellcome Career Award She actively mentors graduate students through UW-Madison’s Microbiology, Cellular & Molecular Pathology, and Cellular & Molecular Biology programs. Her lab welcomes postdoctoral scholars and undergraduates, fostering a collaborative and inclusive research environment. Dr. Knoll’s work continues to advance the understanding of eukaryotic parasite biology and host defense mechanisms, with implications for therapeutics and vaccine development. Her laboratory is based in the Microbial Sciences Building, where she leads a team investigating the complex life cycles and pathogenic strategies of apicomplexan and amoebic parasites.

• Immunology
• Genetics
• Dermatology
• +۲ مورد دیگر

Michele Boniotto is a researcher at the University of Verona's Department of Molecular and Translational Medicine, focusing on immunology, genetics, and dermatology. His work spans molecular mechanisms in skin diseases and evolutionary aspects of host defense peptides. Research Focus Dr. Boniotto's research examines: Genetic factors in hidradenitis suppurativa Beta-defensin evolution and function Aquaporin-3 role in skin homeostasis Photobiomodulation therapies HLA-DR expression in septic shock His publications show interdisciplinary approaches combining molecular biology, clinical dermatology, and bioinformatics to understand complex disease mechanisms. Scientific Contributions 2025: Keratin filament-melanin interactions 2025: Polygenic risk scoring for HS 2024: Aquaporin-3 dysregulation in HS 2023: NCSTN mutations in familial HS 2022: Holistic HS health records 2020: Photobiomodulation for HS

Wei Chaoمشاهده پروفایل

استاد

• Sepsis
• Trauma
• Ischemic Myocardial Injury
• +۷ مورد دیگر

Wei Chao, MD, PhD , is a Professor at the University of Maryland School of Medicine with primary appointments in Anesthesiology and secondary appointments in Physiology . He serves as Vice Chair for Translational Research and Co-Director of the STAR Center . MD from Hunan Medical College, China PhD in Biochemistry, University of Texas Postdoc at University of California, San Diego Dr. Chao's research spans sepsis , trauma , and ischemic myocardial injury , focusing on innate immunity , microRNA , and bioinformatics . His work integrates mouse genetics , physiology , and machine learning to identify biomarkers and therapeutic targets. Recent publications highlight his team's discoveries in extracellular RNA sensing, TLR7 signaling , and coagulopathy in critical illnesses. His 15 most recent articles address topics like sepsis-induced organ injury, miRNA-based diagnostics, and inflammation mechanisms. Dr. Chao has received prestigious awards including the R35 Maximizing Investigators’ Research Award (NIGMS, 2021), Frontiers in Anesthesia Research Award (IARS, 2018-2021), and Colin Mackenzie & Cristina Imle Mentoring Prize (2021). He has been continuously funded by NIH for over 20 years, DoD since 2017, and holds grants from the Air Force and National Science Foundation .

Matthew D. Shouldersمشاهده پروفایل

استاد

• Protein Folding
• Proteostasis Networks
• Directed Evolution
• +۵ مورد دیگر

Matthew D. Shoulders is the Class of 1942 Professor of Chemistry at MIT, holding the MacVicar Faculty Fellowship. He leads the Shoulders Laboratory, which focuses on understanding cellular protein folding mechanisms and developing next-generation protein engineering techniques. His research addresses biotechnology challenges, including improving enzymes for carbon capture and combating collagenopathies. He is affiliated with MIT’s Department of Chemistry, Koch Institute for Integrative Cancer Research, and Broad Institute of MIT and Harvard. Research interests span protein folding, proteostasis networks, viral evolution, and directed evolution applications. Notable projects include studying how chaperones impact oncogene mutations and RNA viruses, and engineering enzymes for climate-resilient agriculture. His lab uses CRISPR/Cas9 and advanced directed evolution tools for biotechnological innovations. Publications highlight contributions to protein stability, viral immune evasion, and collagenopathies. Recent work includes engineering oxygen-resistant RuBisCO and elucidating HIV envelope protein evolution under proteostatic constraints. Awards include the MacVicar Faculty Fellowship and the Class of 1942 Professorship. As a mentor, he advises MIT graduate students and postdocs across chemistry, biology, and engineering. The lab collaborates with institutions like Massachusetts General Hospital and Stanford University. Current projects focus on ER stress pathways in fibrosis, zinc metabolism in liver disease, and ER chaperone modulation for collagenopathies.

Benjamin Schwessingerمشاهده پروفایل

استاد

• Plant Pathology
• Genomics
• Fungal Biology
• +۳ مورد دیگر

Prof Benjamin Schwessinger is a Professor at the Australian National University (ANU), affiliated with the Division of Plant Sciences. His research focuses on plant pathogens, fungal genomics, and the evolutionary dynamics of pathogen adaptation. Key areas include understanding rust fungi biology, host-pathogen interactions, and structural genomic variations in plants like Eucalyptus. He has pioneered methodologies for high-throughput protein secretion optimization in yeast and developed diagnostic tools for invasive pathogens such as Austropuccinia psidii (myrtle rust). Research Interests: Plant-microbe interactions and immunity Fungal genomics and sexual recombination mechanisms Evolving pathogen populations in agricultural systems Genomic tools for disease surveillance and biosecurity His recent work explores the genomic basis of pathogen adaptation, including studies on wheat stripe rust and myrtle rust. Collaborations span fungal pathogenomics, eucalyptus structural genomics, and yeast biotechnology. He leads multiple projects funded by ANU and ARC, including the Plant Biosecurity Training Centre. His lab emphasizes reproducible research practices and early career researcher development. Key projects include: Digital yeast bioprospecting for non-alcoholic beer production Surveillance of airborne pathogens in Australian Botanic Gardens Genome evolution of cereal rust fungi Labs/Teams: Core member of ANU's Plant Biosecurity Group and collaborator in the ARC Training Centre in Plant Biosecurity.

Collin K. Kiefferمشاهده پروفایل

استادیار

• HIV Pathogenesis
• Host-Pathogen Interactions
• Immunology
• +۳ مورد دیگر

Collin K. Kieffer is an Assistant Professor of Microbiology at the University of Illinois Urbana-Champaign, affiliated with the School of Molecular & Cellular Biology, Carl R. Woese Institute for Genomic Biology, and Grainger College of Engineering. His research focuses on HIV pathogenesis using advanced imaging techniques, including multiscale tissue imaging to study viral dissemination and latent reservoirs in humanized animal models and human patient samples. He holds a B.S. in Bacteriology and Genetics from the University of Wisconsin-Madison, a Ph.D. in Biochemistry from the University of Utah, and completed postdoctoral training in Oncology at the University of Utah and in Biology and Biological Engineering at Caltech. Research Interests : Dr. Kieffer’s work integrates cutting-edge imaging methods such as tissue clearing, electron microscopy, and light-sheet fluorescence microscopy to visualize HIV infection dynamics. His lab investigates mechanisms of HIV spread, reservoir persistence under antiretroviral therapy, and evaluates treatment efficacy. Recent projects explore viral interactions with immune cells in tissues, engineering anti-viral red blood cells, and SARS-CoV-2 spike protein biology. Labs & Affiliations : The Kieffer Lab leads interdisciplinary research at the intersection of virology and imaging, collaborating with institutions such as the Carl R. Woese Institute for Genomic Biology. His work bridges basic science and translational medicine, aiming to develop therapeutic strategies against HIV and other viral pathogens.

Zeger Debyserمشاهده پروفایل

استاد

• Lentiviral vector technology
• Molecular virology of HIV
• Molecular Imaging
• +۵ مورد دیگر

Professor Zeger Debyser is a Full Professor at the Faculty of Medicine, KU Leuven, where he serves as Head of the ADVANTAGE research unit (Advanced Disease Modelling, Targeted Drug Discovery and Gene Therapy), Head of the Division of Molecular Medicine, and Head of both the Subdivision Molecular Virology & Drug Discovery and Subdivision Viral Vector Core. He is also a member of the Leuven.IRD - KU Leuven Institute for Rare Diseases and the LKI - KU Leuven Cancer Institute. Prof. Debyser's research focuses on several key areas in molecular medicine. His primary interests include Lentiviral vector technology , Molecular virology of HIV , Molecular Imaging , Drug discovery , and Gene Therapy . His work has significant implications for understanding and treating HIV infection, rare genetic disorders, and cancer. Analysis of Prof. Debyser's recent publications reveals a strong focus on HIV cure strategies, particularly the "block-and-lock" approach, as well as research on LEDGF/p75 protein interactions in various disease contexts including HIV, cancer, and neurological disorders like Rett Syndrome. His team is also making significant contributions to gene editing technologies for cystic fibrosis and other genetic diseases. Prof. Debyser has secured numerous research grants as Promotor or Co-promotor for projects running from 2022 through 2029. These include studies on HIV cure strategies, LEDGF in health and disease, LINE-1 retrotransposition, and gene editing for cystic fibrosis. He actively supervises PhD students and Master's students in his research group. Prof. Debyser leads the ADVANTAGE research unit within the Center for Molecular Medicine at KU Leuven. The center houses multiple laboratories including the Laboratory of Advanced Disease Modelling, Targeted Drug Discovery and Gene Therapy (ADVANTAGE), the Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), and the Laboratory for Neurobiology and Gene Therapy. The center also includes the Leuven Viral Vector Core facility, which supports gene therapy research across multiple laboratories.