معرفی
Dr. John Misasi is an Assistant Professor at Boston University's Chobanian & Avedisian School of Medicine, specializing in Virology, Immunology, and Microbiology. He holds an MD from SUNY Upstate Medical University and a BS from Boston University. His research focuses on antibody discovery, viral pathogenesis, and structural biology. He has contributed to the development of FDA-approved Ebola therapies like mAb114 and leads studies on SARS-CoV-2, MPOX, and Lassa viruses. Dr. Misasi's lab investigates immune evasion mechanisms and antibody-mediated immunity at the National Emerging Infectious Disease Laboratory. He has been recognized with awards including the NIH Director’s Award and multiple NIAID Merit Awards.
Education:
- MD: State University of New York Upstate Medical University
- BS: Boston University
Research Interests:
Dr. Misasi's work centers on understanding antibody mechanisms against high-containment pathogens. His lab uses virology, immunology, and structural biology tools to study viral entry pathways, neutralizing antibodies, and immune evasion strategies. Key areas include:
- Antibody engineering for SARS-CoV-2 and Ebola
- Vaccine design targeting viral glycoproteins
- Host-pathogen interactions in filoviruses
- Therapeutic antibody development
Grants & Awards:
- National Institutes of Health Director’s Award (2020)
- NIAID Merit Award for Ebola Outbreak Response (2018)
- Vaccine Research Center Staff Recognition (2018)
- NIH UGSP and INRO Mentorship Programs (2019-2023)
Labs & Teams:
He leads the National Emerging Infectious Disease Laboratory (NEIDL) team focusing on high-containment pathogens. Collaborations include work at NIH Vaccine Research Center and Harvard Medical School.
