معرفی
Professor Zeger Debyser is a Full Professor at the Faculty of Medicine, KU Leuven, where he serves as Head of the ADVANTAGE research unit (Advanced Disease Modelling, Targeted Drug Discovery and Gene Therapy), Head of the Division of Molecular Medicine, and Head of both the Subdivision Molecular Virology & Drug Discovery and Subdivision Viral Vector Core. He is also a member of the Leuven.IRD - KU Leuven Institute for Rare Diseases and the LKI - KU Leuven Cancer Institute.
Prof. Debyser's research focuses on several key areas in molecular medicine. His primary interests include Lentiviral vector technology, Molecular virology of HIV, Molecular Imaging, Drug discovery, and Gene Therapy. His work has significant implications for understanding and treating HIV infection, rare genetic disorders, and cancer.
Analysis of Prof. Debyser's recent publications reveals a strong focus on HIV cure strategies, particularly the "block-and-lock" approach, as well as research on LEDGF/p75 protein interactions in various disease contexts including HIV, cancer, and neurological disorders like Rett Syndrome. His team is also making significant contributions to gene editing technologies for cystic fibrosis and other genetic diseases.
Prof. Debyser has secured numerous research grants as Promotor or Co-promotor for projects running from 2022 through 2029. These include studies on HIV cure strategies, LEDGF in health and disease, LINE-1 retrotransposition, and gene editing for cystic fibrosis. He actively supervises PhD students and Master's students in his research group.
Prof. Debyser leads the ADVANTAGE research unit within the Center for Molecular Medicine at KU Leuven. The center houses multiple laboratories including the Laboratory of Advanced Disease Modelling, Targeted Drug Discovery and Gene Therapy (ADVANTAGE), the Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), and the Laboratory for Neurobiology and Gene Therapy. The center also includes the Leuven Viral Vector Core facility, which supports gene therapy research across multiple laboratories.