جست‌وجوی استاد و پژوهشگر

Semra Kocabıyıkمشاهده پروفایل

استاد

• Molecular Mechanisms of Protein Thermostability
• Molecular Chaperones
• Proteasome Function
• +۳ مورد دیگر

Semra Kocabıyık is a Professor in the Department of Biological Sciences at Middle East Technical University (METU). Her research focuses on molecular mechanisms of protein stability, molecular chaperones (e.g., small heat-shock proteins), proteasome function, and stress responses in thermoacidophilic archaea, particularly Thermoplasma volcanium. She has contributed to improving enzyme stability and recovery under stress conditions using molecular chaperones. Education: B.Sc. in Agriculture, Ankara University (1972–1977) M.Sc. in Biological Sciences, METU (1980–1982) Ph.D. in Biology, METU (1982–1986) Postdoc, Department of Biology, University of Louisville, USA (1990–1992) Research Interests: Her work integrates biochemistry, molecular biology, and structural biology to study protein stability, stress adaptation in archaea, and enzyme engineering. Key areas include small heat-shock proteins, proteasome regulation, and applications of molecular chaperones in biotechnology. Publications: Recent articles highlight advancements in protein engineering, archaeal stress responses, and structural dynamics of chaperones, reflecting her expertise in extremophile biology and protein function. Achievements: With 95 publications, 139 WoS citations, and 44 thesis advisories, her contributions span academia and biotech applications. Labs & Collaborations: Her lab focuses on archaeal molecular machines and employs techniques like microarray analysis, surface-enhanced Raman spectroscopy (SERS), and molecular cloning.

Brett J. Theelerمشاهده پروفایل

استاد

• Neuro-Oncology
• Rare Primary CNS Neoplasms
• Brain Tumor Research
• +۳ مورد دیگر

Brett J. Theeler is a Professor and Chair of the Department of Neurology at the Uniformed Services University of the Health Sciences (USUHS) School of Medicine. He maintains an active Neuro-Oncology practice at the John P. Murtha Cancer Center within Walter Reed National Military Medical Center and serves as a Clinical Collaborator with the National Institutes of Health, National Cancer Institute, Neuro-Oncology Branch in Bethesda, MD. Dr. Theeler earned his B.S. from Black Hills State University (1996-2001), M.D. from Uniformed Services University (2001-2005), completed Neurology residency at Madigan Army Medical Center (2005-2009), and a Neuro-Oncology fellowship at MD Anderson Cancer Center (2010-2012). His research focuses on rare primary central nervous system neoplasms including pilocytic astrocytomas, pleomorphic xanthoastrocytomas, diffuse midline gliomas and other brain cancers with increased incidence in adolescent and young adult populations. Dr. Theeler has been instrumental in advancing molecular classification of brain tumors and developing targeted therapies for rare CNS tumors through his leadership in the NCI-CONNECT program. His work bridges clinical practice with translational research, emphasizing both patient care and scientific advancement in neuro-oncology. Dr. Theeler's recent publications demonstrate a strong focus on rare CNS tumors, quality of life issues, molecular classification of gliomas, and innovative therapeutic approaches, with significant contributions to understanding tumor biology and improving clinical outcomes. Dean's Award for Academic Excellence, 2001-02 (USUHS) Malcolm B. Carpenter Award, Excellence in Fundamentals of Neuroscience, 2001-02 (USUHS) Captain Calvin B. Early Award for Excellence in Teaching, 2018 Honorary Doctorate of Science from Black Hills State University, 2019 'A' Proficiency Designator by US Army Medical Command, 2019 Inducted into Order of Military Medical Merit (O2M3), 2020 Master Clinician, Neuro-Oncology, 2023 Dr. Theeler has held significant leadership roles including Associate Residency Program Director, Deputy Chief, and Chief of Neurology at Walter Reed National Military Medical Center before becoming Chair of Neurology at USUHS in 2021. He served as Theater Neurologist in Afghanistan (2013) and currently chairs the Programmatic Review Panel for the Rare Cancers Research Program (FY2024-FY2026). His military service as a Colonel in the Army Medical Corps complements his academic and clinical work. As an active participant in the NCI-CONNECT program, Dr. Theeler has co-chaired workshops on rare CNS tumors, particularly focusing on histone mutated midline gliomas. His clinical work at the Murtha Cancer Center provides specialized neuro-oncology care to military personnel and their families, integrating military medicine with cutting-edge academic research.

Cory Hirschمشاهده پروفایل

دانشیار

• Plant Stress Resistance
• Abiotic Stress Biology
• Biotic Stress Responses
• +۳ مورد دیگر

Cory Hirsch is an Associate Professor & Interim Department Head in the Department of Plant Pathology at the University of Minnesota , located in the College of Food, Agriculture and Natural Resource Sciences (CFANS) . His lab focuses on Plant Stress Resistance Biology , leveraging genomic, transcriptomic, and phenomic approaches to understand plant responses to abiotic (e.g., extreme temperatures, salinity) and biotic (e.g., pathogens) stresses. Key research areas include microbiome interactions, pathogen resistance mechanisms, and precision phenotyping. He leads or collaborates on grants from USDA, Minnesota Soybean Council, and the University of Minnesota. Education: PhD and BS in Plant Breeding/Genetics and Biochemistry from the University of Wisconsin-Madison. The Hirsch Lab is based in Stakman Hall , with a focus on translational research bridging basic science and agricultural applications. Research Themes: The lab uses cutting-edge technologies to dissect genomic variation and gene expression dynamics in crops like maize, wheat, and sugar beet. Recent work includes transposable element roles in stress responses, hyperspectral imaging for disease detection, and machine learning for phenotyping. Projects emphasize understanding stress biology to enhance crop resilience. Grants & Collaborations: Notable projects include USDA-funded studies on transposable elements in maize abiotic stress, Minnesota Soybean Council support for soybean disease phenotyping, and collaboration with the Microbial and Plant Genomics Institute. These efforts aim to improve crop productivity and sustainability. Labs & Infrastructure: The lab is equipped with advanced phenotyping tools, including RGB/hyperspectral imaging systems and drone-based platforms. It collaborates with multiple departments and external institutions to advance integrative plant science.

Francesco Iorioمشاهده پروفایل

پژوهشگر

• Computational Biology
• Pharmacogenomics
• Cancer Biology
• +۳ مورد دیگر

Francesco Iorio is a Research Group Leader in Computational Biology at Human Technopole (Milan, Italy), leading research in computational cancer pharmacogenomics and therapeutic target discovery. He holds a PhD from the University of Salerno and TIGEM (Naples), focusing on computational methods for drug discovery. Previously, he was a Senior Bioinformatician at EBI, leading CRISPR-Cas9 screen analyses across cancer cell lines to identify synthetic lethalities and therapeutic targets. He led the Cancer Dependency Map Analytics team at Wellcome Sanger Institute, developing algorithms for integrating large-scale cancer datasets. Since 2019, he serves as a Scientific Advisor to the Cancer Research Horizon–AstraZeneca Functional Genomics Centre. His research integrates computational methods with experimental data to uncover cancer dependencies, drug mechanisms, and biomarkers. Key contributions include tools like CRISPRcleanR for bias correction in CRISPR screens, and CELLector for selecting cancer cell line models. His work spans pharmacogenomics, functional genomics, and CRISPR technologies, with a focus on translating findings into clinical applications. Publications highlight advancements in CRISPR screen analysis, cancer dependency mapping, and drug repositioning. Current projects aim to advance precision medicine through computational frameworks for understanding tumor heterogeneity and therapeutic vulnerabilities.

Erin Heinzenمشاهده پروفایل

دانشیار

• Epilepsy Genetics
• Neurodevelopmental Disorders
• Genomics
• +۳ مورد دیگر

Erin Heinzen is an Associate Professor at the UNC Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, with a joint appointment in the UNC Department of Genetics. She holds a Pharm.D. and Ph.D. from the University of North Carolina at Chapel Hill, followed by postdoctoral training at Duke University. Her research focuses on the genetic and genomic basis of epilepsy disorders, particularly somatic mutations and transcriptomic regulation in neurological diseases. Education: Pharm.D., University of North Carolina at Chapel Hill (2001) Ph.D., Pharmaceutical Sciences, University of North Carolina Chapel Hill (2004) Research Interests: Dr. Heinzen’s lab investigates somatic mutations in epilepsy and brain malformations, using induced pluripotent stem cells and advanced sequencing technologies. Key projects include studying SLC35A2 variants in intractable epilepsy and analyzing transcriptomic changes in brain tissue. Her work has identified 15 epilepsy genes, including the gene for Alternating Hemiplegia of Childhood. Grants & Awards: NIH-funded research, including $7M in collaborative grants to study genetic variants in epilepsy. Active in consortia like Epi4K and ILAE. Labs & Teams: The Heinzen Lab collaborates with neurology, neuropathology, and neurosurgery groups globally, advancing neurogenetics and treatment approaches for intractable seizures.

Julie Sneddonمشاهده پروفایل

دانشیار

• Stem Cell Biology
• Developmental Biology
• Genomics
• +۳ مورد دیگر

Julie Sneddon, PhD, is an Associate Professor in the Department of Cell and Tissue Biology at the University of California San Francisco (UCSF). Her research focuses on pancreatic development and Type I Diabetes, employing stem cell biology, developmental biology, genomics, and tissue engineering to understand cellular microenvironment dynamics. Her laboratory investigates non-epithelial 'niche' cell types in the pancreas to advance regenerative medicine approaches for replacing lost cell and organ function. Research Interests: Dr. Sneddon’s work centers on the cellular and molecular mechanisms underlying pancreatic organogenesis, adult organ function, and disease. Key areas include stem cell niche biology, single-cell analysis of developing tissues, and bioengineering strategies for cell encapsulation and transplantation. Her studies aim to bridge basic science with clinical applications in diabetes treatment and regenerative medicine. Articles Overview: Dr. Sneddon’s publications span topics such as pancreatic developmental genetics, stem cell differentiation, and engineered biomaterials for cell-based therapies. Her work emphasizes multi-omics approaches (e.g., chromatin accessibility, single-cell transcriptomics) to map cell state transitions and gene regulatory networks in developing organs. Labs/Teams: The Sneddon Lab integrates molecular biology, genomics, and bioengineering to address pancreatic biology challenges. Collaborations span UCSF’s Diabetes Center, Tissue Engineering groups, and industry partners in regenerative medicine.

• Microbial Genetics
• Genomics
• Bioinformatics
• +۴ مورد دیگر

Dr. Madhusudan Choudhary is a Professor in the Department of Biological Sciences at Sam Houston State University. He holds a Ph.D. from McMaster University and completed post-doctoral training at Duke University. His research laboratory focuses on microbial genetics, genomics, and bioinformatics using Rhodobacter sphaeroides as a model organism to study bacterial cell-cycle regulation, metabolic innovations through gene duplication, and the evolution of genomic complexity in prokaryotes. Key investigations include chromosome replication origins, duplicate gene expression patterns, and the functional specialization of multipartite genomes. Dr. Choudhary's research spans diverse areas including bacterial responses to microgravity, CRISPR-Cas systems, heavy metal resistance mechanisms, and nanoparticle interactions. He directs studies on transcriptomics under stress conditions and develops computational methods for genome analysis. His work has significant implications for understanding microbial evolution and environmental adaptation.

Yehuda Ben-Shaharمشاهده پروفایل

استاد

• Behavioral Genetics
• Neurogenetics
• Insect Behavior
• +۴ مورد دیگر

Yehuda Ben-Shahar is a Professor of Biology at Washington University in St. Louis, where he has served since 2008. His research integrates behavioral, genetic, genomic, and molecular approaches to investigate the genetic architectures underlying animal behavior, primarily using Drosophila melanogaster and honey bees as model systems. He maintains laboratory facilities at the Bayer Laboratory (Room 406) and conducts field research at the Tyson Research Center. Ben-Shahar earned his PhD from the University of Illinois at Urbana-Champaign. His research focuses on how specific genes in neuronal circuits govern behaviors like feeding and mating decisions, with significant contributions to understanding honey bee social behavior evolution. Recent work centers on the gut microbiome's role in nestmate recognition and developing genetic tools for non-model insects. His publication record reveals consistent innovation in behavioral genetics, with recent emphasis shifting toward microbial influences on social behavior and neural circuit analysis. Early work established foundational insights into gene-behavior relationships, while current research explores chemosensory mechanisms across insect and mammalian systems. Scientific recognition includes: Multiple Faculty of 1000 'Must read' designations (2002, 2007, 2009) Cover features in Science (2009) and Journal of Experimental Biology (2002) 'Mutant of the Month' in Nature Genetics (2006) Extensive media coverage including NPR, CBC Radio, and major newspapers Ben-Shahar mentors graduate students including Cassie Vernier (whose 2020 Science Advances paper defined gut microbiome roles in hive membership) and has supervised numerous undergraduates. His lab operates through collaborative grants supporting research at the intersection of genetics, neuroscience, and social behavior. The Ben-Shahar Lab maintains active research teams at the Bayer Laboratory for molecular work and the Tyson Research Center for honey bee studies, with recent projects involving cyborg locust development and odor-guided navigation research.

• Database Management Systems
• Query Processing and Optimization
• Approximate Query Processing
• +۶ مورد دیگر

Dr. Feng (George) Yu is an Associate Professor of Computer Science and Information Systems at Youngstown State University in Youngstown, Ohio. He serves as the Campus Champion of NSF Extreme Science and Engineering Discovery Environment (XSEDE) at YSU and has been collaborating with XSEDE and Pittsburgh Supercomputing Center since 2014 to bring national workshop series on High-Performance Computing to YSU. Ph.D. in Computer Science, Southern Illinois University (2013) M.S. in Pure Mathematics, Shandong University (2008) B.S. in Information and Computation Science, Northeastern University (2005) Dr. Yu's primary research focuses on database management systems, particularly Approximate Query Processing (AQP) for big data analytics. His work spans multiple areas including Cloud Computing , Blockchain , NoSQL Databases , and Bioinformatics . His recent research has centered on error assessment for AQP using bootstrap sampling techniques, as evidenced by his 2024 publications AQPrius and Error Assessment for Multi-Join AQP . He has also made significant contributions to plant genomics through alternative splicing analysis in various crops. His publication trends show a consistent focus on query processing and optimization, with a recent shift toward more sophisticated error estimation techniques in approximate query processing. His work bridges theoretical database research with practical applications in bioinformatics and educational technology, as seen in his 2024 paper on computing curriculum accessibility for students with ASD. Best of QUEST 2024 Finalist (Faculty Advisor) Research Professorship (2023, 2022, 2019, 2018) Distinguished Professor in Scholarship (2020) Best Paper Award at International Conference on Software Engineering and Data Engineering (2019) Faculty Membership in The Honor Society of Phi Kappa Phi (2022) Dr. Yu actively mentors undergraduate researchers, having advised students including Govardhan Gula for the BEST of QUEST project on accelerating bootstrap resampling, and led a CREU-funded project on recommender systems with undergraduate researchers Alyssa Adams, Olivia Bindas, Maddie Cope, and Elizabeth Durflinger. His research has been supported by external funding sources including Amazon Inc. and the Computer Research Association. He directs the YSU Data Lab , which focuses on data-oriented sciences and operates multiple high-performance research clouds including Sarah Cloud and YSU STEM Cloud. The lab conducts cutting-edge research in approximate query processing, blockchain, and heterogeneous cloud infrastructure.

LIU Boxiangمشاهده پروفایل

استادیار

• Genomics
• Bioinformatics
• Machine Learning
• +۳ مورد دیگر

Asst Prof LIU Boxiang holds the position of Assistant Professor and NUS Presidential Young Professorship at the Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore (NUS), within the Faculty of Science. His research focuses on integrating multi-omics approaches with computational methods to study complex diseases such as coronary artery disease and age-related macular degeneration. He specializes in developing statistical and machine learning tools for genomic analysis, including eQTL mapping and deep learning architectures for gene expression regulation. Education: BA in Biophysics (Illinois Wesleyan University), MS and PhD in Bioinformatics (Stanford University). He contributed to the GTEx consortium and is part of the Asian Immune Diversity Atlas (AIDA) initiative. His lab develops methods like ANTseq for ancestry determination and scPrediXcan for cell-type-specific transcriptome studies. Research Interests: Functional genomics, eQTL analysis, deep learning in biomedicine, and computational tools for omics data integration. His work bridges disciplines such as natural language processing and computer vision with biological questions. Scientific Awards: NUS Presidential Young Professorship (2021). His lab's innovations include ParaMed, a biomedical translation dataset, and LinearDesign for optimized mRNA stability. Advising and Grants: Leads the Liu Lab (boxiangliulab.com), focusing on single-cell genomics, mitochondrial dynamics, and computational biomedicine. Collaborates on projects like the RESET cohort study for cardiovascular disease prevention.

Yongjin Parkمشاهده پروفایل

استادیار

• Single-cell Analysis
• Immunology
• Epigenomics
• +۳ مورد دیگر

Yongjin Park Yongjin Park is an Assistant Professor in the Department of Statistics at the University of British Columbia (UBC) . He is affiliated with the Causal Path Lab , focusing on computational biology and genomics. His research integrates statistical methods with large-scale genomic data to understand complex diseases like multiple sclerosis (MS) and Alzheimer’s, particularly through single-cell analysis and epigenomic studies. Affiliations: Faculty of Science, UBC; BC Cancer Research Research Interests: Single-cell RNA sequencing, immune cell dynamics, epigenomics, and regulatory genomics in disease contexts. Key projects include analyzing T-cell subtypes in MS patients and developing scalable computational tools for genomic data (e.g., CoCoA-diff, pseudobulk projection methods). His lab emphasizes translating genomic insights into clinical applications. Awards & Honors Data Science Award Dr. John and Barbara Petkau Scholarship Killam Graduate Teaching Assistant Award Margaret Wylie Memorial Scholarship in Statistics Lab & Collaborations The Causal Path Lab collaborates on projects involving Alzheimer’s disease progression, placental methylation, and cancer genomics. Recent work includes single-nucleus transcriptomic analysis of brain vasculature and epigenetic drivers of disease.

Ashley Wolfمشاهده پروفایل

استادیار

• Gut microbiome composition
• Microbial metabolism
• Bacterial competition
• +۳ مورد دیگر

Ashley Wolf is an Assistant Professor at the University of California, Berkeley, holding a joint appointment in the School of Public Health and the Center for Computational Biology. Her research focuses on understanding gut microbiome composition and its roles in mammalian health, particularly exploring diet, microbial competition, and host factors influencing microbiome structure. Education: PhD in Systems Biology from Harvard University (2010s), AB in Molecular Biology from Princeton University (2000s) Her lab integrates human microbiome data, laboratory models, and computational methods to design microbial therapeutics. Key research areas include microbial metabolism of dietary components, bacterial competition dynamics, and microbiome impacts on host physiology. Selected publications highlight work on microbiome bioremediation, bile acid-glucose metabolism links, and mitochondrial RNA processing in human and model organisms. No awards explicitly listed, though her work aligns with emerging trends in systems biology and public health.

Thomas Vondriskaمشاهده پروفایل

استاد

• Epigenomics
• Cardiovascular Disease
• Heart Failure Mechanisms
• +۴ مورد دیگر

Thomas Vondriska is a Professor in the Departments of Anesthesiology & Perioperative Medicine and Physiology at the David Geffen School of Medicine, UCLA. His research focuses on epigenomic mechanisms driving cardiovascular disease and heart failure. He leads interdisciplinary teams investigating chromatin structure, gene expression dynamics, and environmental-genetic interactions in disease susceptibility. Research Interests: Epigenomic regulation of heart failure, chromatin architecture, cardiac hypertrophy, and translational epigenetic medicine. Active NIH grants include studies on small molecule therapies targeting chromatin, epigenomic resilience, and non-coding RNA mechanisms. Publications emphasize systems biology approaches to cardiac epigenomics, including single-cell transcriptomics and chromatin conformation analysis. Key topics include fibrotic remodeling, nuclear mechanics, and circadian histone turnover in heart development. Funding: Principal Investigator on multiple NIH grants (R01, R21) totaling over $10M since 2012 Labs: Epigenomic Cardiac Biology Lab at UCLA

Ellis Patrickمشاهده پروفایل

دانشیار

• Bioinformatics
• Biomedical Data Science
• Statistical Bioinformatics
• +۶ مورد دیگر

Associate Professor Ellis Patrick is an applied statistician and bioinformatician affiliated with the University of Sydney's School of Mathematics and Statistics, the Westmead Institute for Medical Research, and the Sydney Precision Data Science Centre. His research focuses on developing bioinformatics tools to analyze high-dimensional biomedical data, with applications in disease treatment, precision medicine, and understanding molecular drivers of conditions like Alzheimer’s, MS, and cancer. He holds a PhD from the University of Sydney and postdoctoral experience at Harvard Medical School and The Broad Institute. Education: PhD in statistical bioinformatics from the University of Sydney. Postdoctoral training included joint appointments at Brigham and Women’s Hospital, Harvard Medical School, and The Broad Institute of MIT and Harvard. Research Interests: Specializes in statistical bioinformatics, spatial omics, and high-dimensional data analysis, with emphasis on translational research in infectious diseases, organ transplantation, cardiovascular disorders, neurodegeneration, and oncology. His work combines computational methods with clinical data to uncover disease mechanisms and improve therapeutic strategies. Grants & Collaborations: Recent grants include PrecisionGO (MRFF-funded), White matter lesion transcriptomics (National MS Society), and studies on coronary artery disease and graft failure prediction. Collaborates widely with medical researchers, leveraging interdisciplinary teams to tackle complex health challenges. Labs & Teams: Leads the Bioinformatics Cluster at the Sydney Precision Data Science Centre, integrating computational and experimental approaches to advance precision health initiatives.

Jun Allardمشاهده پروفایل

استاد

• Mathematical Biology
• Computational Biology
• Cell Mechanics
• +۴ مورد دیگر

Jun Allard is a Professor at the University of California, Irvine, with joint appointments in the Department of Mathematics and Department of Physics and Astronomy. He is affiliated with the Center for Complex Biological Systems and the NSF-Simons Center for Multiscale Cell Fate Research. Education includes: Ph.D. Applied Mathematics, University of British Columbia (2011) M.Sc. Physics, Dalhousie University (2007) B.Sc. Mathematical Physics, Queen's University (2005) His research specializes in mathematical and computational modeling of cellular and biomolecular mechanics. Key interests include how cells utilize force, space, and time to solve problems, with applications in immune cell signaling, cytoskeletal dynamics, and intracellular transport. His work combines theoretical models with experimental collaborations to uncover fundamental biological mechanisms. Recent publications (2021-2025) predominantly focus on computational approaches to cellular processes, including molecular transport mechanisms, immune receptor dynamics, and cytoskeletal organization. These studies employ advanced stochastic modeling, biophysical simulations, and quantitative experimental methods to reveal principles governing cellular behavior. Scientific awards include: UCI Chancellor's Award for Distinguished Fostering of Undergraduate Research (2015) Emerging Diversity Scholar, National Center for Institutional Diversity (2016) Honorable Mention, NSF Graduate Research Fellowship (2012) He has advised over 12 doctoral students and leads the Allard Lab, which develops computational models for cell mechanics. Major grants include NSF awards for research on molecular-tether reactions (DMS-2052668), nanoparticle adhesion (CBET-1929565), and multiscale cell fate (DMS-1763272). The lab collaborates internationally with experimental groups and participates in interdisciplinary initiatives including the Chemical and Materials Physics program.