Julie Sneddon

Julie Sneddon, PhD, is an Associate Professor in the Department of Cell and Tissue Biology at the University of California San Francisco (UCSF). Her research focuses on pancreatic development and Type I Diabetes, employing stem cell biology, developmental biology, genomics, and tissue engineering to understand cellular microenvironment dynamics. Her laboratory investigates non-epithelial 'niche' cell types in the pancreas to advance regenerative medicine approaches for replacing lost cell and organ function.

Research Interests:
Dr. Sneddon’s work centers on the cellular and molecular mechanisms underlying pancreatic organogenesis, adult organ function, and disease. Key areas include stem cell niche biology, single-cell analysis of developing tissues, and bioengineering strategies for cell encapsulation and transplantation. Her studies aim to bridge basic science with clinical applications in diabetes treatment and regenerative medicine.

Articles Overview:
Dr. Sneddon’s publications span topics such as pancreatic developmental genetics, stem cell differentiation, and engineered biomaterials for cell-based therapies. Her work emphasizes multi-omics approaches (e.g., chromatin accessibility, single-cell transcriptomics) to map cell state transitions and gene regulatory networks in developing organs.

Labs/Teams:
The Sneddon Lab integrates molecular biology, genomics, and bioengineering to address pancreatic biology challenges. Collaborations span UCSF’s Diabetes Center, Tissue Engineering groups, and industry partners in regenerative medicine.