معرفی
Thomas Vondriska is a Professor in the Departments of Anesthesiology & Perioperative Medicine and Physiology at the David Geffen School of Medicine, UCLA. His research focuses on epigenomic mechanisms driving cardiovascular disease and heart failure. He leads interdisciplinary teams investigating chromatin structure, gene expression dynamics, and environmental-genetic interactions in disease susceptibility.
Research Interests: Epigenomic regulation of heart failure, chromatin architecture, cardiac hypertrophy, and translational epigenetic medicine. Active NIH grants include studies on small molecule therapies targeting chromatin, epigenomic resilience, and non-coding RNA mechanisms.
Publications emphasize systems biology approaches to cardiac epigenomics, including single-cell transcriptomics and chromatin conformation analysis. Key topics include fibrotic remodeling, nuclear mechanics, and circadian histone turnover in heart development.
- Funding: Principal Investigator on multiple NIH grants (R01, R21) totaling over $10M since 2012
- Labs: Epigenomic Cardiac Biology Lab at UCLA
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