Jessica J. Wang

Dr. Jessica J. Wang is an Hs Associate Clinical Professor in the Department of Medicine at the University of California, Los Angeles (UCLA). She serves as Director of the UCLA Cardiovascular Genetics Clinic and Principal Investigator of the UCLA Inherited Cardiovascular Disease Registry. Her research focuses on understanding genetic contributions to cardiovascular health, particularly in cardiac remodeling and inherited cardiomyopathies using mouse models. Dr. Wang holds dual MD and PhD degrees from the University of Pennsylvania and UCLA, respectively, and has received NIH funding for her work on MYH14 and stress-induced cardiac remodeling.

Education

• BS in Biology, Massachusetts Institute of Technology (2000)
• MD in Medicine, University of Pennsylvania (2004)
• PhD in Human Genetics, UCLA (2014)

Research Interests

Dr. Wang’s research integrates clinical cardiology with genetic analysis to identify novel genes and pathways involved in cardiovascular diseases. Key areas include:

• Genetic basis of cardiac hypertrophy and heart failure
• Mouse model systems for studying cardiomyopathies
• Translational approaches for inherited cardiovascular disorders

Grants & Funding

• NIH R03HL157012 (2022–2024): Investigating MYH14’s role in cardiomyocyte hypertrophy
• NIH K08HL133491 (2017–2022): Functional validation of Myh14 in cardiac remodeling

Labs & Collaborations

As PI of the UCLA Inherited Cardiovascular Disease Registry, she leads efforts to archive clinical and genetic data for novel gene discovery. Collaborators include Aldons Lusis and Thomas Vondriska, focusing on systems genetics and precision medicine.