جست‌وجوی استاد و پژوهشگر

• Protein Folding
• Neurodegenerative Diseases
• Biochemistry
• +۵ مورد دیگر

Jill Zitzewitz is an Associate Professor at UMass Chan Medical School , with affiliations in the Department of Radiology , Biochemistry and Molecular Biotechnology , Neurology , and NeuroNexus Institute . She also holds positions in graduate programs including the Morningside Graduate School of Biomedical Sciences in Biochemistry and Molecular Biotechnology , Neuroscience , and Translational Science . Education : B.A. in Chemistry from Carthage College (1986) PhD in Bioorganic Chemistry from Washington University in St. Louis (1991) Postdoctoral training in Protein Folding at Pennsylvania State University with an NIH Fellowship Research interests focus on protein misfolding and its role in neurodegenerative diseases , particularly amyotrophic lateral sclerosis (ALS) . Her work investigates molecular interactions stabilizing native protein conformations and develops biophysical methods to probe folding, misfolding, and aggregation of ALS-linked proteins like SOD1 and TDP-43 . This includes thermodynamic analyses and applications of mass spectrometry and fluorescence anisotropy to study structural rearrangements and stability cores. Publications highlight trends in protein folding dynamics , ALS pathogenesis , and structural biology . Key subfields include conformational transitions , hydrophobic interactions , RNA-binding proteins , and therapeutic development for neurodegenerative disorders. Collaborative Networks include co-authors such as Francesca Massi , Daryl Bosco , and John Landers . She is part of teams in Translational Anatomy and NeuroNexus Institute , with physical neighbors like Andreas Bergmann and Daniel Caffrey .

• Cancer Pharmacology
• Enzyme Activity Imaging
• Drug Response Modeling
• +۳ مورد دیگر

Sampreeti Jena is a Researcher in the Department of Experimental and Clinical Pharmacology at the University of Minnesota. Her work focuses on cancer pharmacology, enzyme activity imaging, and computational drug discovery, particularly for castration-resistant prostate cancer and pediatric central nervous system tumors. Institution: University of Minnesota Department: Experimental and Clinical Pharmacology Her research interests include: Using single-cell transcriptomics and pan-cancer analysis to identify therapeutic vulnerabilities in heterogeneous tumors Developing fluorescence lifetime imaging (FLIM) probes for kinase activity measurement Investigating protein stability in pharmaceutical formulations Creating computational models for drug response prediction Recent publications highlight her contributions to precision oncology through: Digital tumor modeling for therapeutic inference Identification of pan-histology immunomodulatory targets Advancements in FLIM probe technology Excipient interaction studies affecting protein stability Current projects include: Dynamic Digital Tumors for Precision Oncology (University of California San Diego, 2024-2025) Genetic mechanisms underlying sexual dimorphism in cancer (University of Colorado & NIH, 2024-2026)

Markita Landryمشاهده پروفایل

دانشیار

• Nanomaterials
• Fluorescence Microscopy
• Sensors
• +۳ مورد دیگر

Markita Landry is an Associate Professor of Chemical and Biomolecular Engineering at the University of California, Berkeley, affiliated with the College of Engineering. Her research spans interdisciplinary applications of nanotechnology in neuroscience and plant engineering. 2022: Chan-Zuckerberg Biohub Young Investigator, Vilcek Prize for Creative Promise 2021: National Academies Committee member, Dreyfus Teacher-Scholar Award 2020: NSF CAREER Award, CZI Deep Tissue Imaging Award 2019: Bakar Fellow, Sloan Foundation Fellow Research Interests: The Landry Lab focuses on synthetic bio-mimetic nanocomposites for Molecular Imaging and Targeted Bio-Delivery . In neuroscience, they engineer optical probes for neuromodulators like dopamine and serotonin to study disorders such as addiction, Huntington's, and Parkinson's. In plant engineering, they develop nanoparticle platforms for DNA/RNA delivery to crops (e.g., wheat, cotton) without transgene integration, aiming to enhance yield, stress tolerance, and regulatory compliance for GMO alternatives. Publication Trends: Her recent work highlights nanomaterials in in vivo neurotransmitter monitoring and plant genetic engineering. Key themes include CRISPR-compatible delivery systems, non-invasive RNA/DNA vectors, and infrared fluorescence for disease modeling. Scientific Awards: 2022 Vilcek Prize for Creative Promise in Biomedical Science 2020 NSF CAREER Award 2019 Bakar Fellow 2018 DARPA Young Faculty Award 2017 Kavli Fellow (National Academies of Engineering) Labs & Teams: The Landry Lab at UC Berkeley pioneers synthetic nanocomposites for biomedical and agricultural applications. Their collaborative work bridges the interface of materials science, neuroscience, and plant biotechnology, supported by grants from organizations like the Chan-Zuckerberg Biohub and the Dreyfus Foundation.

Yamuna Krishnanمشاهده پروفایل

استاد

• Biochemistry
• Molecular Biology
• Cellular Biology
• +۴ مورد دیگر

Yamuna Krishnan is a Professor in the Department of Chemistry at the University of Chicago. Her research focuses on developing DNA nanodevices for quantitative chemical imaging of organelles , particularly mapping ion dynamics in lysosomes and acidic organelles. Key Contributions: Solved a 30-year problem in molecular sensing by quantifying lumenal calcium in acidic organelles, identifying the first human lysosomal Ca²⁺ importer . Publications highlight her work in DNA-based fluorescent probes , lysosomal function , and tumor targeting via macrophage modulation . Her technology enables studies in live multicellular organisms and human patient cells . Recent articles: Acc. Chem. Res. (2024), Nat. Methods (2019), Nat. Nanotechnol. (2021), Sci. Adv. (2024). She actively collaborates with institutions like the Institut Pasteur, delivering seminars on Intracellular Electrophysiology in 2025.

• Regenerative Medicine
• Tissue Repair
• Skeletal System
• +۵ مورد دیگر

Meriem Lamghari is a full Professor at the Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal. She leads the NeuroSkeletal Circuits (NESK) research group at INEB/i3S, focusing on neuro-skeletal interactions, tissue engineering, and regenerative medicine. She received her Ph.D. in Osteoarticular Biology, Biomechanics and Biomaterials from Université Jussieu Paris 7 in 1999. Established research line on neuro-skeletal interactions in 2009 Coordinated H2020 RESTORE project on smart nanobiomaterials Partner in FLAMIN-GO, sinPain, PREMUROSA, and BonePain EU projects Her research bridges neuroscience and skeletal biology, using microfluidic platforms to study neuro-immune interactions in osteoarthritis, bone metastasis, and tissue regeneration. She has secured extensive national and international funding, including multiple Horizon 2020 and MSCA grants. Recent publications highlight her work on neuro-immune interplay in joint pain, 4D bioprinting for cartilage repair, and metastasis-on-chip systems. Her lab develops innovative approaches to bone regeneration involving nanobiomaterials and sympathetic nervous system modulation .

Kirsten Knoxمشاهده پروفایل

مدرس

• Plant Transport Mechanisms
• Molecular Biology
• Cell Biology
• +۴ مورد دیگر

Kirsten Knox is a Lecturer in Molecular Biosciences at the School of Life Sciences, University of Glasgow. She received her BSc in Genetics and Immunology from the University of Aberdeen and a PhD from the University of York under Dame Professor Ottoline Leyser. Education: BSc (Aberdeen), PhD (York) Research Focus: Plant transport mechanisms, plasmodesmata dynamics, phloem function, and circadian regulation Teaching: Course Coordinator for Level 2 Genes, Molecules and Cells and Level 3 Biochemistry

Jacques Luxمشاهده پروفایل

پژوهشگر

• Theranostics
• Nanomedicine
• Ultrasound Imaging
• +۱۲ مورد دیگر

Jacques Lux is a researcher in the Department of Radiology at the University of Texas Southwestern Medical Center, where he contributes to the Translational Research in Ultrasound Theranostics (TRUST) program. His work bridges chemistry, materials science, and biomedical imaging, with a focus on developing next-generation diagnostic and therapeutic agents. Education: PhD in Chemistry, University of Strasbourg, under Nobel laureate Jean-Pierre Sauvage Postdoctoral training at Faculty of Pharmacy, Strasbourg Postdoctoral research at Scripps Research Institute (La Jolla, CA) Postdoctoral and Research Scientist roles at UCSD Dr. Lux's research focuses on theranostics , particularly the design of activatable ultrasound agents that enable both cancer detection and targeted therapy through drug release or high-intensity focused ultrasound. His work also encompasses stimuli-responsive nanomaterials , including light- and enzyme-activatable systems, and the development of high-relaxivity MRI contrast agents using nanogel platforms. These efforts aim to improve imaging specificity, reduce toxicity, and enable image-guided interventions. The 15 most recent publications highlight a strong trend in multimodal imaging , nanoparticle engineering , and translational biomedical applications . Key themes include ultrasound-triggered therapies, oxygen-generating nanoparticles for hypoxia relief, biosensors for infection detection, and light-responsive drug delivery systems. The research integrates supramolecular chemistry, polymer science, and clinical imaging to create smart, responsive platforms for precision medicine. Scientific Awards: No awards explicitly mentioned in the provided text. Dr. Lux has been actively involved in research grants and collaborative projects, particularly in the development of nanoparticle-based theranostic systems and image-guided cancer therapies . His collaborations span chemistry, radiology, and bioengineering, often involving translational studies aimed at clinical application. He has contributed to the design of novel contrast agents, enzyme-loaded nanoparticles, and activatable probes, suggesting sustained funding from biomedical research agencies. He is a key member of the TRUST program at UT Southwestern, a multidisciplinary team focused on advancing ultrasound theranostics. His lab likely involves a team of postdoctoral researchers, graduate students, and engineers working on nanoparticle synthesis, in vivo imaging, and preclinical validation of novel agents. The emphasis on translational research indicates strong institutional and possibly industry partnerships.

Ian Lipscombمشاهده پروفایل

مدرس ارشد

• Medical Applications
• Biomechanics
• Prion Research
• +۴ مورد دیگر

Ian Lipscomb is the Head of Engineering and Computing at the University of Chichester, with a PhD in mathematical modeling of knee joint injuries from Cardiff University. He has over 10 years of teaching experience across Higher, Further, and Private educational institutions, including leadership roles in two Colleges. His research spans biomedical applications of shape memory metals, prion contamination prevention on surgical instruments, and flipped learning methodologies in education. BEng (Hons), PhD, DTLLS, QTLS Fellow of the Institute of Mathematics and its Applications (FIMA) Fellow of the Royal Statistical Society (FRSS) Fellow of the Higher Education Academy (FHEA) His work focuses on prion research , piezoelectric materials , and biomedical engineering , with a recent book on shape memory metals in medicine. Publications include collaborations with Southampton and Keevil on surgical steel contamination and ceramic breakdown mechanisms. Scientific awards include fellowships in FIMA, FRSS, and FHEA, reflecting his contributions to mathematics, statistics, and education. He has developed protocols for protein contamination detection and investigated electrical breakdown in ceramics under environmental stressors. Ian's research on flipped learning and surgical hygiene has led to 10+ publications, emphasizing interdisciplinary applications in medical physics and materials science. His academic journey includes postdoctoral research on human prion diseases and engineering education innovation.

• Cell Biology
• Biochemistry
• Chemistry
• +۷ مورد دیگر

Hyunil Jo, PhD is a Specialist in the School of Pharmacy at the University of California, San Francisco (UCSF) . His research focuses on integrin signaling, protein design, and therapeutic targeting of disease mechanisms such as hepatic fibrosis and neurodegenerative disorders. Education: BS (2001) and MS (2003) in Pharmacy, Seoul National University PhD (2008) in Chemistry, University of Pennsylvania Research Interests: Integrin biology dominates his work, with studies on α2β1 and α5β1 integrins in airway disease, renal fibrosis, and vascular smooth muscle function. He also pioneers de novo protein design for drug-binding specificity and uses biophysical probes (e.g., fluorescent amino acids, infrared spectroscopy) to study protein structure and dynamics. His virology work includes SARS-CoV-2 envelope protein analysis, while earlier projects explored malaria and amyloid fibril formation. Publications (2025-2010): His 35+ publications span integrin-mediated diseases, custom protein engineering, and structural studies of amyloid and viral proteins. Key journals include Science , Nature Chemical Biology , PNAS , and Cell . Awards: Department of Defense Predoctoral Training Award for Prostate Cancer (2005-2008) Grants: Principal Investigator, NIH/NIDDK R01DK137892 (2023-2028) - Targeting Acid Ceramidase for Hepatic Fibrogenesis Co-Principal Investigator, NIH R61HL163725 (2022-2024) - Mitigation of Smooth Muscle Force via Integrin Alpha2Beta1 Inhibitors Collaborations: Work with William DeGrado (UCSF) on protein engineering Collaborations with Dean Sheppard (UCSF) in integrin research Partnerships in vaccine development and virology projects

Hans Sennمشاهده پروفایل

مدرس

• Computational Chemistry
• Quantum Mechanics/Molecular Mechanics
• Enzymatic Reactions
• +۶ مورد دیگر

Hans Senn is a Lecturer in Theoretical & Computational Chemistry at the School of Chemistry, University of Glasgow. His research focuses on computational approaches to chemical reactions, particularly through combined quantum mechanics/molecular mechanics (QM/MM) methods. He leads a research group dedicated to understanding enzymatic reactions, transition-metal chemistry, and catalytic systems through advanced computational techniques. His research interests encompass computational studies of enzymatic reactions using QM/MM, computational transition-metal and organometallic chemistry including homogeneous catalysis, first-principles and QM/MM molecular dynamics, sampling techniques and free-energy calculations, and modeling of solvation effects. His work bridges theoretical chemistry with practical applications in biochemistry and materials science, with recent publications showing increased interdisciplinary collaboration across physical chemistry, biochemistry, and materials science domains. His recent publication trend reveals a strong focus on multiscale modeling approaches, with significant contributions to understanding enzymatic mechanisms, molecular vibrations in complex systems, and the development of computational tools for spectroscopic prediction. His work spans both fundamental theoretical developments and applications to biological and materials systems. Dr sc nat (ETH Zurich) MRSC As an educator, Senn serves as Head of Chemistry-1 and teaches advanced courses including Symmetry and Bonding (Chem-3) and Theoretical and Computational Chemistry (Chem-4). His research group actively collaborates across disciplines, with recent work involving teams in biophysics, materials science, and medicinal chemistry. He has presented at major conferences including Gordon Research Conferences and ACS National Meetings, demonstrating his active engagement with the international computational chemistry community.

Steven Magennisمشاهده پروفایل

استاد

• Physical Chemistry
• Single-Molecule Fluorescence Spectroscopy
• DNA Structure & Dynamics
• +۳ مورد دیگر

Dr. Steven Magennis is a Professor in Physical Chemistry at the School of Chemistry , University of Glasgow. His research focuses on single-molecule fluorescence techniques to study DNA structure, dynamics, and reactivity. Key Research Areas : Physical Chemistry, Biochemistry, DNA Structural Biology Institution : University of Glasgow, UK His work leverages fluorescent nucleobase analogs , two-photon excitation , and single-molecule FRET to unravel DNA conformational changes and interactions. Recent studies include metallation effects on DNA dynamics and trinucleotide repeat behavior . Selected trends from 15 most recent articles highlight expertise in fluorescent probe development , DNA junction analysis , and optical detection methods . Collaborations span institutions in the UK and beyond.

• Optical Gas Sensing
• Porphyrin-Based Materials
• Langmuir-Blodgett Films
• +۴ مورد دیگر

José María Pedrosa Poyato is a Professor at the Universidad Pablo de Olavide within the Department of Physical, Chemical and Natural Systems. He is affiliated with the Center for Nanoscience and Sustainable Technologies (CNATS) and previously contributed to the research group QUIFICON (Physical Chemistry of Condensed Phases and Interfaces). Email: jmpedpoy@upo.es Research Interests: His work focuses on optical gas sensing using advanced materials like porphyrin-based composites , metal-organic frameworks (MOFs) , and Langmuir-Blodgett films . Key areas include molecular aggregation behavior, sensor fabrication, and detection of volatile organic compounds (VOCs) and toxic gases such as NO2, H2S, and amines. He also explores applications in electronic olfactory systems for food quality analysis (e.g., olive oil) and environmental monitoring. Publication Trends: Recent studies highlight the integration of MOFs into transparent films, cross-responsive sensor arrays, and enhanced fluorescence techniques for multi-analyte detection. His work spans materials synthesis, surface characterization, and practical sensor development using spectroscopic and nanofabrication methods.

Gail Carlsonمشاهده پروفایل

دانشیار

• Environmental health
• Toxicology
• Climate change
• +۵ مورد دیگر

Gail Carlson is an Associate Professor of Environmental Studies at Colby College, with a focus on environmental health impacts and policy. Her work bridges scientific research and advocacy, particularly in the context of Maine's environmental challenges. Education: B.A. in Chemistry from St. Olaf College (1988) Ph.D. in Biochemistry from the University of Wisconsin (1994) Her research explores the intersection of environmental contaminants, climate change, and human health. Key areas include chemical pollution in Maine ecosystems, environmental justice, and legislative strategies to mitigate ecological harm. She mentors students in advocacy campaigns and policy analysis. Recent publications highlight her dual expertise in environmental toxicology and policy analysis, ranging from PFAS contamination studies to climate change adaptation frameworks in vulnerable regions like the Caribbean.

Barbara A. Bairdمشاهده پروفایل

استاد

• Biophysical Chemistry
• Chemical Biology
• Signal Transduction
• +۴ مورد دیگر

Barbara A. Baird is the Horace White Professor in the Department of Chemistry and Chemical Biology at Cornell University, affiliated with the College of Arts and Sciences. She directs the Baird-Holowka research group investigating receptor-mediated signaling mechanisms using advanced biophysical methods. Her educational background includes a BS from Knox College, PhD from Cornell University, and Damon Runyon Postdoctoral Fellowship at the National Cancer Institute, NIH. Research Focus: Professor Baird's work integrates quantitative microscopy and biophysical approaches to study membrane receptor dynamics, particularly focusing on: IgE-FcεRI signaling in mast cells for allergic/inflammatory responses Lipid membrane organization and phase behavior in signal transduction Alpha-synuclein mechanisms in neurodegenerative diseases Nanoparticle applications for biomedicine and imaging Publication Trends: Recent articles (2018-2025) demonstrate: Advanced imaging techniques (FCS, super-resolution microscopy) Membrane biophysics and lipid-protein interactions Neurodegenerative disease mechanisms (Parkinson's-focused) Nanotechnology development for drug delivery and diagnostics Awards & Recognition: Distinguished Women in Chemistry (2021) Academic Activities: Professor Baird teaches graduate and undergraduate courses including Basics of Biophysical Chemistry and Introduction to Chemical Biology Research . She mentors students through the Baird-Holowka research group, which develops innovative approaches to study cellular signaling and membrane dynamics.

Claudio Vinegoniمشاهده پروفایل

استادیار

• Optical Imaging
• Biomedical Imaging
• Machine Learning
• +۵ مورد دیگر

Claudio Vinegoni is an Assistant Professor of Radiology at Harvard Medical School and Massachusetts General Hospital, with over three decades of expertise in optical imaging modalities and biomedical data analysis. His research focuses on system-level biological interactions in disease states like cancer and cardiovascular disorders, combining advanced microscopy with machine learning techniques. His lab develops novel optical imaging systems for in vivo and ex vivo applications, including fluorescence anisotropy , two-photon microscopy , and tensor imaging for whole-organ analysis. Recent work emphasizes deep learning integration with fluorescence data processing. Publications span Nature and Science journals, covering Drug-target engagement quantification Cardiac microstructure visualization High-resolution atherosclerosis imaging GAN-based microscopy enhancement His academic background includes a PhD and MS in Physics from University of Geneva and Universita di Trento, with thesis work on Raman spectroscopy and telecom fiber metrology.