Jacques Lux

Jacques Lux is a researcher in the Department of Radiology at the University of Texas Southwestern Medical Center, where he contributes to the Translational Research in Ultrasound Theranostics (TRUST) program. His work bridges chemistry, materials science, and biomedical imaging, with a focus on developing next-generation diagnostic and therapeutic agents.

Education:

• PhD in Chemistry, University of Strasbourg, under Nobel laureate Jean-Pierre Sauvage
• Postdoctoral training at Faculty of Pharmacy, Strasbourg
• Postdoctoral research at Scripps Research Institute (La Jolla, CA)
• Postdoctoral and Research Scientist roles at UCSD

Dr. Lux's research focuses on theranostics, particularly the design of activatable ultrasound agents that enable both cancer detection and targeted therapy through drug release or high-intensity focused ultrasound. His work also encompasses stimuli-responsive nanomaterials, including light- and enzyme-activatable systems, and the development of high-relaxivity MRI contrast agents using nanogel platforms. These efforts aim to improve imaging specificity, reduce toxicity, and enable image-guided interventions.

The 15 most recent publications highlight a strong trend in multimodal imaging, nanoparticle engineering, and translational biomedical applications. Key themes include ultrasound-triggered therapies, oxygen-generating nanoparticles for hypoxia relief, biosensors for infection detection, and light-responsive drug delivery systems. The research integrates supramolecular chemistry, polymer science, and clinical imaging to create smart, responsive platforms for precision medicine.

Scientific Awards:

• No awards explicitly mentioned in the provided text.

Dr. Lux has been actively involved in research grants and collaborative projects, particularly in the development of nanoparticle-based theranostic systems and image-guided cancer therapies. His collaborations span chemistry, radiology, and bioengineering, often involving translational studies aimed at clinical application. He has contributed to the design of novel contrast agents, enzyme-loaded nanoparticles, and activatable probes, suggesting sustained funding from biomedical research agencies.

He is a key member of the TRUST program at UT Southwestern, a multidisciplinary team focused on advancing ultrasound theranostics. His lab likely involves a team of postdoctoral researchers, graduate students, and engineers working on nanoparticle synthesis, in vivo imaging, and preclinical validation of novel agents. The emphasis on translational research indicates strong institutional and possibly industry partnerships.